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Searching for up to 100 curated homologs for 8501229 FitnessBrowser__Miya:8501229 (293 a.a.)

Found high-coverage hits (≥70%) to 33 curated proteins.

Removed hits that are identical to the query, leaving 32

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

DVU0114 ATP phosphoribosyltransferase (EC 2.4.2.17) from Desulfovibrio vulgaris Hildenborough JW710
    88% identity, 100% coverage of query (500 bits)

2vd3A / O27550 The structure of histidine inhibited hisg from methanobacterium thermoautotrophicum
    33% identity, 98% coverage of query (147 bits)

Q9Z472 ATP phosphoribosyltransferase (EC 2.4.2.17) from Corynebacterium glutamicum (see 2 papers)
    33% identity, 96% coverage of query (114 bits)

Build an alignment

Build an alignment for 8501229 and 3 homologs with ≥ 30% identity

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Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

HisG / b2019 ATP phosphoribosyltransferase (EC 2.4.2.17) from Escherichia coli K-12 substr. MG1655 (see paper)
hisG / P60757 ATP phosphoribosyltransferase (EC 2.4.2.17) from Escherichia coli (strain K12) (see 36 papers)
HIS1_ECOLI / P60757 ATP phosphoribosyltransferase; ATP-PRT; ATP-PRTase; EC 2.4.2.17 from Escherichia coli (strain K12) (see 4 papers)
hisG / RF|NP_416523 ATP phosphoribosyltransferase from Escherichia coli K12 (see paper)
    28% identity, 100% coverage of query (99.0 bits)

HIS1_MYCTU / P9WMN1 ATP phosphoribosyltransferase; ATP-PRT; ATP-PRTase; EC 2.4.2.17 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
5lhtA / P9WMN1 Atp phosphoribosyltransferase from mycobacterium tuberculosis in complex with the allosteric activator 3-(2-thienyl)-l-alanine (see paper)
    28% identity, 96% coverage of query (97.1 bits)

HIS1_SALTY / P00499 ATP phosphoribosyltransferase; ATP-PRT; ATP-PRTase; EC 2.4.2.17 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    28% identity, 100% coverage of query (97.1 bits)

1nh8A Atp phosphoribosyltransferase (atp-prtase) from mycobacterium tuberculosis in complex with amp and histidine
    29% identity, 96% coverage of query (95.5 bits)

HIS1 / GB|CAA58751.1 ATP phosphoribosyltransferase; EC 2.4.2.17 from Candida albicans (see paper)
    27% identity, 95% coverage of query (94.4 bits)

1h3dA / P60757 Structure of the e.Coli atp-phosphoribosyltransferase (see paper)
    28% identity, 98% coverage of query (92.4 bits)

1q1kA Structure of atp-phosphoribosyltransferase from e. Coli complexed with pr-atp
    28% identity, 98% coverage of query (92.4 bits)

his1 / RF|NP_594525.1 ATP phosphoribosyltransferase; EC 2.4.2.17 from Schizosaccharomyces pombe (see paper)
his1 / AAA92790.1 ATP phosphoribosyltransferase from Schizosaccharomyces pombe (see paper)
    26% identity, 95% coverage of query (90.9 bits)

5u99A Transition state analysis of adenosine triphosphate phosphoribosyltransferase
    30% identity, 96% coverage of query (90.9 bits)

7dahC / Q9KSX4 Adenosine triphosphate phosphoribosyltransferase from vibrio cholerae in complex with atp and prpp
    27% identity, 98% coverage of query (89.4 bits)

Q5HSJ4 ATP phosphoribosyltransferase (EC 2.4.2.17) from Campylobacter jejuni (see 3 papers)
Q9PM78 ATP phosphoribosyltransferase (EC 2.4.2.17) from Campylobacter jejuni (see paper)
    25% identity, 100% coverage of query (85.9 bits)

4yb6A / Q5HSJ4 Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with the inhibitors amp and histidine (see paper)
    25% identity, 99% coverage of query (84.3 bits)

4yb7A Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with atp
    25% identity, 99% coverage of query (84.3 bits)

4yb7C Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with atp
    25% identity, 99% coverage of query (84.0 bits)

1usyG / Q9X0D2 Atp phosphoribosyl transferase (hisg:hisz) complex from thermotoga maritima (see paper)
    31% identity, 74% coverage of query (82.0 bits)

Psest_3299 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas stutzeri RCH2
    28% identity, 73% coverage of query (79.3 bits)

4yb6E Adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni in complex with the inhibitors amp and histidine
    26% identity, 99% coverage of query (78.2 bits)

PP_0965 ATP phosphoribosyltransferase (EC 2.4.2.17) from Pseudomonas putida KT2440
    27% identity, 73% coverage of query (73.9 bits)

HSERO_RS20350 ATP phosphoribosyltransferase (EC 2.4.2.17) from Herbaspirillum seropedicae SmR1
    25% identity, 70% coverage of query (72.0 bits)

Q56UT2 ATP phosphoribosyltransferase (EC 2.4.2.17) from Odontarrhena lesbiaca (see paper)
    26% identity, 97% coverage of query (67.8 bits)

5ubgA Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni with bound phosphoribosyl-atp
    25% identity, 74% coverage of query (65.1 bits)

Q56US5 ATP phosphoribosyltransferase (EC 2.4.2.17) from Alyssum montanum (see paper)
    25% identity, 99% coverage of query (63.2 bits)

5ubiA Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni with bound prpp
    25% identity, 73% coverage of query (62.8 bits)

Q56UT3 ATP phosphoribosyltransferase (EC 2.4.2.17) from Odontarrhena lesbiaca (see paper)
    23% identity, 100% coverage of query (61.6 bits)

AtATP-PRT1 / Q9S762 ATP-phosphoribosyl transferase (EC 2.4.2.17) from Arabidopsis thaliana (see paper)
HIS1A_ARATH / Q9S762 ATP phosphoribosyltransferase 1, chloroplastic; ATP-PRTase 1; AtATP-PRT1; EC 2.4.2.17 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9S762 ATP phosphoribosyltransferase (EC 2.4.2.17) from Arabidopsis thaliana (see paper)
    24% identity, 96% coverage of query (60.1 bits)

G7JFL4 ATP phosphoribosyltransferase (EC 2.4.2.17) from Medicago truncatula (see paper)
    25% identity, 97% coverage of query (60.1 bits)

6czmE / G7JFL4 Crystal structure of medicago truncatula atp-phosphoribosyltransferase in tense form (see paper)
    25% identity, 95% coverage of query (59.7 bits)

AtATP-PRT2 / Q8GSJ1 ATP-phosphoribosyl transferase (EC 2.4.2.17) from Arabidopsis thaliana (see paper)
HIS1B_ARATH / Q8GSJ1 ATP phosphoribosyltransferase 2, chloroplastic; ATP-PRTase 2; AtATP-PRT2; EC 2.4.2.17 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    23% identity, 97% coverage of query (59.3 bits)

5ub9A Catalytic core domain of adenosine triphosphate phosphoribosyltransferase from campylobacter jejuni
    25% identity, 73% coverage of query (59.3 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory