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Searching for up to 100 curated homologs for 8501284 FitnessBrowser__Miya:8501284 (730 a.a.)

Found high-coverage hits (≥70%) to 38 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

7v74A Thermostabilized human prestin in complex with sulfate
    31% identity, 76% coverage of query (246 bits)

7v75A Thermostabilized human prestin in complex with salicylate (see paper)
    31% identity, 76% coverage of query (244 bits)

SUT41_ARATH / Q9FY46 Sulfate transporter 4.1, chloroplastic; AST82 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    30% identity, 75% coverage of query (242 bits)

7lhvA / Q9FY46 Structure of arabidopsis thaliana sulfate transporter atsultr4;1 (see paper)
    30% identity, 75% coverage of query (240 bits)

Build an alignment

Build an alignment for 8501284 and 4 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

TC 2.A.53.1.3 / P53391 The molybdate (high affinity)/Sulfate (lower affinity) transporter, ShsT1 from Stylosanthes hamata (see paper)
SHST1 / CAA57710.1 high affinity sulphate transporter from Stylosanthes hamata (see paper)
    27% identity, 75% coverage of query (224 bits)

ST1 / CAA65291.1 high affinity sulphate transporter from Hordeum vulgare (see paper)
    27% identity, 77% coverage of query (224 bits)

SULT2_CHLRE / A8J6J0 Proton/sulfate cotransporter 2 from Chlamydomonas reinhardtii (Chlamydomonas smithii) (see 2 papers)
TC 2.A.53.1.8 / A8J6J0 The proton:sulfate symporter, SulP from Chlamydomonas reinhardtii (see paper)
    28% identity, 76% coverage of query (223 bits)

SHST2 / CAA57711.1 high affinity sulphate transporter from Stylosanthes hamata (see paper)
    27% identity, 75% coverage of query (223 bits)

SUT11_ARATH / Q9SAY1 Sulfate transporter 1.1; AST101; High-affinity sulfate transporter 1; Hst1At from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
TC 2.A.53.1.7 / Q9SAY1 High affinity sulfate transporter, Sultr1.1 regulated differently from Sultr1.2 (2.A.53.1.6) from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    27% identity, 76% coverage of query (222 bits)

Y1739_MYCTU / P9WGF7 Probable sulfate transporter Rv1739c from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
TC 2.A.53.4.2 / P71997 Sulfate transporter, Rv1739c from Mycobacterium tuberculosis
    31% identity, 75% coverage of query (214 bits)

SUT21_ARATH / O04722 Sulfate transporter 2.1; AST68 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    29% identity, 77% coverage of query (213 bits)

SUT12_ARATH / Q9MAX3 Sulfate transporter 1.2 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
TC 2.A.53.1.6 / Q9MAX3 The sulfate transporter, Sultr1.2 with C-terminal STAS domain that is required both for activity and biogenesis/stability (Shibagaki and Grossman, 2006). It physically interacts with 0-acetylserine (thiol)lyase (cysteine synthetase) via its STAS domain. This interaction stimulates the activity of from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
SULTR1;2 / RF|NP_849899.1 sulfate transporter 1.2 from Arabidopsis thaliana (see paper)
    27% identity, 77% coverage of query (202 bits)

SUT13_ARATH / Q9FEP7 Sulfate transporter 1.3 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    28% identity, 77% coverage of query (199 bits)

SUT22_ARATH / P92946 Sulfate transporter 2.2; AST56; AtH14 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    27% identity, 76% coverage of query (197 bits)

SUT33_ARATH / Q9SXS2 Probable sulfate transporter 3.3; AST91 from Arabidopsis thaliana (Mouse-ear cress)
    28% identity, 71% coverage of query (196 bits)

TC 2.A.53.1.4 / P53393 Low-affinity sulfate:H+ symporter, Sut3 from Stylosanthes hamata (see paper)
    28% identity, 76% coverage of query (195 bits)

bst3.1 / CAE46442.1 sulphate transporter from Brassica napus (see paper)
    26% identity, 75% coverage of query (191 bits)

S2611_HUMAN / Q86WA9 Sodium-independent sulfate anion transporter; Solute carrier family 26 member 11 from Homo sapiens (Human) (see 3 papers)
    29% identity, 72% coverage of query (191 bits)

S2611_MOUSE / Q80ZD3 Sodium-independent sulfate anion transporter; Kidney brain anion transporter; KBAT; Solute carrier family 26 member 11 from Mus musculus (Mouse) (see 5 papers)
    29% identity, 73% coverage of query (189 bits)

TC 2.A.53.3.13 / Q1J2S8 Fumarate (Na+-independent anion) transporter, SLC26dg of 499 aas and 14 TMSs from Deinococcus geothermalis (strain DSM 11300)
    29% identity, 71% coverage of query (189 bits)

TC 2.A.53.1.12 / Q0P7I2 Symbiotic sulfate transporter-1, SST1 of 645 aas from Lotus japonicus
    26% identity, 75% coverage of query (188 bits)

5da0A / Q1J2S8 Structure of the the slc26 transporter slc26dg in complex with a nanobody (see paper)
    29% identity, 70% coverage of query (188 bits)

7lguA / P58743 Structure of human prestin in the presence of nacl (see paper)
    26% identity, 71% coverage of query (186 bits)

S2611_CAVPO / G3C7W6 Sodium-independent sulfate anion transporter; Solute carrier family 26 member 11 from Cavia porcellus (Guinea pig) (see paper)
TC 2.A.53.1.9 / G3C7W6 Slc26a11 Cl-/oxalate or sulfate (but not bicarbonate) exchanger from Cavia porcellus (see paper)
    29% identity, 71% coverage of query (179 bits)

TC 2.A.53.4.1 / P72770 Sulfate transporter (see paper)
    27% identity, 76% coverage of query (175 bits)

TC 2.A.53.3.1 / O07488 Sulfate permease from Yersinia enterocolitica (see paper)
    27% identity, 71% coverage of query (167 bits)

8sgwC / A0A8D0Z6H8 Pendrin in complex with chloride
    22% identity, 76% coverage of query (142 bits)

8sieC Pendrin in complex with bicarbonate
    22% identity, 76% coverage of query (142 bits)

8shcC Pendrin in complex with niflumic acid
    22% identity, 76% coverage of query (142 bits)

S26A2_MOUSE / Q62273 Sulfate transporter; Diastrophic dysplasia protein homolog; ST-OB; Solute carrier family 26 member 2 from Mus musculus (Mouse) (see 4 papers)
    23% identity, 74% coverage of query (140 bits)

SULH3_SCHPO / O59782 Probable sulfate permease C320.05 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    22% identity, 75% coverage of query (139 bits)

S26A1_HUMAN / Q9H2B4 Sulfate anion transporter 1; SAT-1; Solute carrier family 26 member 1 from Homo sapiens (Human) (see 3 papers)
TC 2.A.53.2.16 / Q9H2B4 Sulfate anion transporter 1 (SAT-1 or SAT1) (Solute carrier family 26 member 1); anion exchanger.  Transports chloride, sulfate, bicarbonate and oxalate (Regeer et al. 2003; Lee et al. 2003).  The mouse and rat orthologues have the same specificities and functions. Loss in mice  is associated with hyperoxalurea and calcium oxalate kidney stones, and specific mutations when heterozygous in humans cause urolithiasis (Dawson et al. 2013).  When homozygous, they can cause severe nephrocalcinosis from Homo sapiens (see 5 papers)
    26% identity, 74% coverage of query (138 bits)

S26A1_RAT / P45380 Sulfate anion transporter 1; SAT-1; Canalicular sulfate transporter; Solute carrier family 26 member 1; Sulfate/carbonate antiporter from Rattus norvegicus (Rat) (see 7 papers)
TC 2.A.53.2.2 / P45380 Canicular sulfate:HCO3- antiporter (Slc26a1) from Rattus norvegicus (Rat) (see paper)
    24% identity, 74% coverage of query (133 bits)

S26A1_MOUSE / P58735 Sulfate anion transporter 1; SAT-1; Solute carrier family 26 member 1 from Mus musculus (Mouse) (see 4 papers)
    24% identity, 74% coverage of query (132 bits)

SULX_YEAST / P53394 Putative sulfate transporter YPR003C from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    23% identity, 71% coverage of query (132 bits)

BICA_SYNY3 / Q55415 Bicarbonate transporter BicA from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
    26% identity, 73% coverage of query (129 bits)

S26A2_HUMAN / P50443 Sulfate transporter; Diastrophic dysplasia protein; Solute carrier family 26 member 2 from Homo sapiens (Human) (see 9 papers)
TC 2.A.53.2.1 / P50443 Sulfate/anion transporter (diastrophic dysplasia protein) (SLC26A2). It catalyzes electroneutral SO4-, OH- from Homo sapiens (Human) (see 12 papers)
    22% identity, 77% coverage of query (125 bits)

S26A2_BOVIN / Q9BEG8 Sulfate transporter; Solute carrier family 26 member 2 from Bos taurus (Bovine) (see paper)
    21% identity, 75% coverage of query (123 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory