Sites on a Tree

 

Searching for up to 100 curated homologs for 8501682 FitnessBrowser__Miya:8501682 (373 a.a.)

Found high-coverage hits (≥70%) to 17 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.5.40 / Q93PJ7 NikCD, component of Nickel uptake porter, NikAB(CD)E from Helicobacter hepaticus
    46% identity, 71% coverage of query (255 bits)

CNTC_STAA8 / Q2FVE9 Metal-staphylopine import system permease protein CntC from Staphylococcus aureus (strain NCTC 8325 / PS 47) (see 2 papers)
TC 3.A.1.5.43 / Q2FVE9 Nickel ABC transporter, permease protein, putative, component of The metal-staphylopine (nicotianamine-like metalophore) complex uptake system, CntABCDF from Staphylococcus aureus (strain NCTC 8325)
    39% identity, 75% coverage of query (211 bits)

CNTC_STAAM / A0A0H3JU73 Metal-staphylopine import system permease protein CntC from Staphylococcus aureus (strain Mu50 / ATCC 700699) (see paper)
    39% identity, 75% coverage of query (211 bits)

TC 3.A.1.5.20 / P42063 AppC, component of 5-6 amino acyl oligopeptide transporter AppA-F from Bacillus subtilis (see 2 papers)
appC / GB|CAB12997.1 oligopeptide ABC transporter, permease protein AppC from Bacillus subtilis (see paper)
    40% identity, 71% coverage of query (201 bits)

GsiD / b0832 glutathione ABC transporter membrane subunit GsiD (EC 7.4.2.10) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
gsiD / P75799 glutathione ABC transporter membrane subunit GsiD (EC 7.4.2.10) from Escherichia coli (strain K12) (see paper)
GSID_ECOLI / P75799 Glutathione transport system permease protein GsiD from Escherichia coli (strain K12) (see paper)
P75799 ABC-type glutathione transporter (EC 7.4.2.10) from Escherichia coli (see paper)
TC 3.A.1.5.11 / P75799 Hypothetical ABC transporter permease protein yliD, component of Glutathione porter, YliABCD or GsiABCD from Escherichia coli (see 4 papers)
    41% identity, 75% coverage of query (201 bits)

TC 3.A.1.5.2 / P26904 DppC aka DCIAC, component of Dipeptide porter. Also transports δ-aminolevulinic acid (ALA) and heme from Bacillus subtilis (see 3 papers)
    39% identity, 73% coverage of query (180 bits)

DPPC_PSEAB / A0A0H2ZFV0 Di/tripeptide transport system permease protein DppC from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
    39% identity, 76% coverage of query (175 bits)

TC 3.A.1.5.39 / W0WMS8 Dipeptide transport system permease protein dppC, component of Di- and tri-peptide transporter, DppBCDF with periplasmic substrate binding receptors, A1, A3, A5, A7 and A9, each with differing specificities for peptides from Pseudomonas aeruginosa MH38
    39% identity, 76% coverage of query (175 bits)

TC 3.A.1.5.33 / I0C487 NikC, component of The Nickel (Ni2+) uptake porter, NikABCDE from Staphylococcus aureus subsp. aureus 71193
    34% identity, 72% coverage of query (175 bits)

DdpC / b1485 putative D,D-dipeptide ABC transporter membrane subunit DdpC from Escherichia coli K-12 substr. MG1655 (see 4 papers)
DDPC_ECOLI / P77463 Probable D,D-dipeptide transport system permease protein DdpC from Escherichia coli (strain K12) (see paper)
    34% identity, 73% coverage of query (174 bits)

Q5V9S0 ABC-type oligopeptide transporter (EC 7.4.2.6) from Vibrio fluvialis (see paper)
TC 3.A.1.5.22 / Q5V9S0 OppC, component of The peptide transporter OppA,B,C,D,F (influences biofilm formation; Lee et al., 2004). Similar to 3.A.1.5.1, OppA is similar to the Vibrio furnissii OppA that provides several functions: hemolysis, antibiotic resistance, and virulence from Vibrio fluvialis (see paper)
    33% identity, 80% coverage of query (166 bits)

OppC / b1245 murein tripeptide ABC transporter / oligopeptide ABC transporter inner membrane subunit OppC (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
oppC / P0AFH6 murein tripeptide ABC transporter / oligopeptide ABC transporter inner membrane subunit OppC (EC 7.4.2.6) from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.5.41 / P0AFH6 Oligopeptide transport system permease protein OppC, component of Oligopeptide transporter, OppABCDF/MppA/YgiS from Escherichia coli (strain K12)
    37% identity, 72% coverage of query (164 bits)

TC 3.A.1.5.23 / Q9F9T5 EppC, component of The Ethylene diamine tetraacetate (EDTA) uptake porter, EppABCD (see 2 papers)
    36% identity, 77% coverage of query (161 bits)

TC 3.A.1.5.1 / P08006 OppC aka STM1744, component of Oligopeptide porter (also takes up amino glycoside antibiotics such as kanamycin, streptomycin and neomycin as well as cell wall-derived peptides such as murein tripeptide). It transports substrate peptides of 2-5 amino acids with highest affinity for tripeptides. Also transports δ-aminolevulinic acid (ALA). [May be regulated by PTS Enzyme INtr-aspartokinase.] ATP-binding to OppDF may result in donation of peptide to OppBC and simultaneous release of OppA from Salmonella typhimurium (see 3 papers)
oppC / GB|AAV77094.1 oligopeptide ABC transporter, permease protein OppC from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
    36% identity, 72% coverage of query (161 bits)

TC 3.A.1.5.37 / B1W1M0 Putative peptide ABC transporter permease protein, component of The ABC BldKA-E (SGR_2418-2414) oligopeptide transport system. It controls aerial mycelium formation on glucose media. Probably involved in extracellular peptide signalling (Akanuma et al. 2011).  Probably orthologous to 3.A.1.5.35 from Streptomyces griseus subsp. griseus (strain JCM 4626 / NBRC 13350)
    34% identity, 81% coverage of query (160 bits)

TC 3.A.1.5.4 / O30544 AccE, component of Agrocinopine (an opine)/Agrocin 84 (an antibiotic) porter from Agrobacterium radiobacter (see 3 papers)
    35% identity, 71% coverage of query (139 bits)

SapC / b1292 putrescine ABC exporter membrane protein SapC (EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
SapC / P0AGH5 putrescine ABC exporter membrane protein SapC (EC 7.6.2.16) from Escherichia coli (strain K12) (see 2 papers)
SAPC_ECOLI / P0AGH5 Putrescine export system permease protein SapC from Escherichia coli (strain K12) (see 2 papers)
    30% identity, 72% coverage of query (112 bits)

Build an alignment

Build an alignment for 8501682 and 17 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory