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Searching for up to 100 curated homologs for 8501746 FitnessBrowser__Miya:8501746 (175 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

B1Y931 fumarate hydratase (subunit 2/2) (EC 4.2.1.2) from Pyrobaculum neutrophilum (see paper)
    44% identity, 99% coverage of query (133 bits)

Q141Z6 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Paraburkholderia xenovorans (see paper)
    44% identity, 94% coverage of query (131 bits)

6unzA / E9AE57 Crystal structure of cytosolic fumarate hydratase from leishmania major (see paper)
    40% identity, 93% coverage of query (122 bits)

FUM2_LEIMA / E9AE57 Fumarate hydratase 2; Fumarase 2; LmFH-2; EC 4.2.1.2 from Leishmania major (see 3 papers)
    40% identity, 93% coverage of query (122 bits)

6uqnB Crystal structure of r173a variant of cytosolic fumarate hydratase from leishmania major in a complex with fumarate and s-malate
    40% identity, 93% coverage of query (122 bits)

6msnA Crystal structure of cytosolic fumarate hydratase from leishmania major in a complex with inhibitor thiomalate
    40% identity, 93% coverage of query (122 bits)

6uoiA Crystal structure of cytosolic fumarate hydratase from leishmania major in a complex with malonate
    40% identity, 93% coverage of query (122 bits)

FumA / b1612 fumarase A (EC 4.2.1.2; EC 5.3.2.2) from Escherichia coli K-12 substr. MG1655 (see 16 papers)
fumA / P0AC33 fumarase A (EC 4.2.1.2; EC 5.3.2.2) from Escherichia coli (strain K12) (see 15 papers)
FUMA_ECOLI / P0AC33 Fumarate hydratase class I, aerobic; Fumarase A; Oxaloacetate keto--enol-isomerase; OAAKE isomerase; Oxaloacetate tautomerase; EC 4.2.1.2; EC 5.3.2.2 from Escherichia coli (strain K12) (see 4 papers)
P0AC33 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Escherichia coli (see paper)
fumA fumarate hydratase class I, aerobic; EC 4.2.1.2 from Escherichia coli K12 (see 8 papers)
    41% identity, 97% coverage of query (119 bits)

FumB / b4122 fumarase B (EC 4.2.1.2; EC 4.2.1.81) from Escherichia coli K-12 substr. MG1655 (see 20 papers)
fumB / P14407 fumarase B (EC 4.2.1.2; EC 4.2.1.81) from Escherichia coli (strain K12) (see 21 papers)
FUMB_ECOLI / P14407 Fumarate hydratase class I, anaerobic; D-tartrate dehydratase; Fumarase B; EC 4.2.1.2; EC 4.2.1.81 from Escherichia coli (strain K12) (see 3 papers)
P14407 fumarate hydratase (EC 4.2.1.2); (S)-2-methylmalate dehydratase (EC 4.2.1.34) from Escherichia coli (see paper)
fumB / GB|AAC77083.1 fumarate hydratase class I, anaerobic; EC 4.2.1.2 from Escherichia coli K12 (see 5 papers)
FumB / EW|b4122 anaerobic class I fumarate hydratase (fumarase B) from Escherichia coli K12 (see 3 papers)
    40% identity, 97% coverage of query (116 bits)

Q8U063 fumarate hydratase (subunit 1/2) (EC 4.2.1.2) from Pyrococcus furiosus (see paper)
    44% identity, 97% coverage of query (115 bits)

Q8X999 fumarate hydratase (EC 4.2.1.2) from Escherichia coli (see paper)
    38% identity, 97% coverage of query (107 bits)

6msoA / Q4QAU9 Crystal structure of mitochondrial fumarate hydratase from leishmania major in a complex with inhibitor thiomalate (see paper)
    36% identity, 85% coverage of query (100 bits)

FUM1_LEIMA / Q4QAU9 Fumarate hydratase 1, mitochondrial; Fumarase 1; LmFH-1; EC 4.2.1.2 from Leishmania major (see 2 papers)
    36% identity, 85% coverage of query (100 bits)

YgjB / b3062 L(+)-tartrate dehydratase subunit β (EC 4.2.1.32) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
ttdB / P0AC35 L(+)-tartrate dehydratase subunit β (EC 4.2.1.32) from Escherichia coli (strain K12) (see 4 papers)
TTDB_ECOLI / P0AC35 L(+)-tartrate dehydratase subunit beta; L-TTD beta; EC 4.2.1.32 from Escherichia coli (strain K12) (see 2 papers)
ttdB L(+)-tartrate dehydratase subunit beta; EC 4.2.1.32 from Escherichia coli K12 (see paper)
    35% identity, 96% coverage of query (91.3 bits)

Build an alignment

Build an alignment for 8501746 and 14 homologs with ≥ 30% identity

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory