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Searching for up to 100 curated homologs for AO353_03400 FitnessBrowser__pseudo3_N2E3:AO353_03400 (419 a.a.)

Found high-coverage hits (≥70%) to 24 curated proteins.

Removed hits that are identical to the query, leaving 23

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO356_05200 D-mannose isomerase (EC 5.3.1.7) from Pseudomonas fluorescens FW300-N2C3
    82% identity, 99% coverage of query (654 bits)

Pf1N1B4_597 D-mannose isomerase (EC 5.3.1.7) from Pseudomonas fluorescens FW300-N1B4
    84% identity, 100% coverage of query (652 bits)

PS417_22150 D-mannose isomerase (EC 5.3.1.7) from Pseudomonas simiae WCS417
    75% identity, 99% coverage of query (596 bits)

MANI_PSEC1 / A0A0P9JFY5 D-mannose isomerase; PsMIaseA; EC 5.3.1.7 from Pseudomonas cannabina pv. alisalensis (strain ATCC BAA-566 / CFBP 6866 / ICMP 15200 / BS91) (see paper)
    69% identity, 98% coverage of query (558 bits)

SquS / b3880 sulfoquinovose isomerase (EC 5.3.1.31; EC 5.3.1.7) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yihS / P32140 sulfoquinovose isomerase (EC 5.3.1.31; EC 5.3.1.7) from Escherichia coli (strain K12) (see 6 papers)
SQUS_ECOLI / P32140 Sulfoquinovose isomerase; SQ isomerase; Sulfoquinovose-sulfofructose isomerase; SQ-SF isomerase; EC 5.3.1.31 from Escherichia coli (strain K12) (see 3 papers)
yihS / RF|NP_418316 uncharacterized sugar isomerase yihS from Escherichia coli K12 (see paper)
    47% identity, 97% coverage of query (386 bits)

SQUS_SALTY / Q8ZKT7 Sulfoquinovose isomerase; SQ isomerase; Sulfoquinovose-sulfofructose isomerase; SQ-SF isomerase; EC 5.3.1.31 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
    46% identity, 97% coverage of query (384 bits)

7ag4D / Q8ZKT7 Crystal structure of active site mutant of sq isomerase (yihs-h248a) from salmonella enterica in complex with sulfofructose (sf) (see paper)
    46% identity, 97% coverage of query (380 bits)

2zblA Functional annotation of salmonella enterica yihs-encoded protein
    46% identity, 97% coverage of query (380 bits)

MANI_THEFU / A0A077LPS9 D-mannose isomerase; EC 5.3.1.7 from Thermobifida fusca (Thermomonospora fusca)
    52% identity, 92% coverage of query (357 bits)

PGA1_c16670 D-mannose isomerase (EC 5.3.1.7) from Phaeobacter inhibens BS107
    38% identity, 92% coverage of query (224 bits)

BPHYT_RS02050 D-mannose isomerase (EC 5.3.1.7) from Burkholderia phytofirmans PsJN
    33% identity, 81% coverage of query (161 bits)

MANI_MARM1 / F2JVT6 D-mannose isomerase; MI; EC 5.3.1.7 from Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1) (see paper)
    31% identity, 88% coverage of query (160 bits)

Ac3H11_2078 D-mannose isomerase (EC 5.3.1.7) from Acidovorax sp. GW101-3H11
    34% identity, 77% coverage of query (148 bits)

HSERO_RS03650 Mannose isomerase (EC 5.3.1.7) from Herbaspirillum seropedicae SmR1
    30% identity, 84% coverage of query (126 bits)

Sama_0560 D-mannose isomerase (EC 5.3.1.7) from Shewanella amazonensis SB2B
    30% identity, 81% coverage of query (124 bits)

Build an alignment

Build an alignment for AO353_03400 and 15 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

C6VW66 cellobiose epimerase (EC 5.1.3.11) from Dyadobacter fermentans (see 2 papers)
    25% identity, 80% coverage of query (73.6 bits)

F5ITJ6 cellobiose epimerase (EC 5.1.3.11) from Dysgonomonas gadei (see paper)
    20% identity, 78% coverage of query (66.2 bits)

A5FA14 cellobiose epimerase (EC 5.1.3.11) from Flavobacterium johnsoniae (see 2 papers)
    23% identity, 79% coverage of query (63.9 bits)

C6XVU9 cellobiose epimerase (EC 5.1.3.11) from Pedobacter heparinus (see 2 papers)
    24% identity, 82% coverage of query (62.8 bits)

G0GBL0 cellobiose epimerase (EC 5.1.3.11) from Spirochaeta thermophila (see paper)
    24% identity, 76% coverage of query (60.1 bits)

D0MF61 cellobiose epimerase (EC 5.1.3.11) from Rhodothermus marinus (see paper)
    26% identity, 92% coverage of query (60.1 bits)

E0RU15 cellobiose epimerase (EC 5.1.3.11) from Spirochaeta thermophila (see 2 papers)
    25% identity, 81% coverage of query (56.6 bits)

bfce / Q5LH66 cellobiose 2-epimerase (EC 5.1.3.11) from Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) (see 3 papers)
CEEP_BACFN / Q5LH66 Cellobiose 2-epimerase; CE; Mannobiose 2-epimerase; MBE; EC 5.1.3.11 from Bacteroides fragilis (strain ATCC 25285 / DSM 2151 / CCUG 4856 / JCM 11019 / NCTC 9343 / Onslow) (see 2 papers)
Q5LH66 cellobiose epimerase (EC 5.1.3.11) from Bacteroides fragilis (see 3 papers)
    23% identity, 78% coverage of query (50.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory