Searching for up to 100 curated homologs for AO353_05965 AO353_05965 aromatic amino acid transporter (466 a.a.)
Found high-coverage hits (≥70%) to 65 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PfGW456L13_4291 L-tryptophan transporter from Pseudomonas fluorescens GW456-L13
90% identity, 100% coverage of query (846 bits)
AO356_18530 L-tyrosine transporter from Pseudomonas fluorescens FW300-N2C3
73% identity, 100% coverage of query (709 bits)
RR42_RS33495 L-phenylalanine:H+ symporter AroP from Cupriavidus basilensis FW507-4G11
68% identity, 98% coverage of query (630 bits)
AroR / b0112 aromatic amino acid:H+ symporter AroP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
aroP / P15993 aromatic amino acid:H+ symporter AroP from Escherichia coli (strain K12) (see 6 papers)
AROP_ECOLI / P15993 Aromatic amino acid transport protein AroP; Aromatic amino acid:H(+) symporter AroP; General aromatic amino acid permease; General aromatic transport system from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli (see 6 papers)
66% identity, 100% coverage of query (615 bits)
H281DRAFT_04042 phenylacetate transporter from Paraburkholderia bryophila 376MFSha3.1
70% identity, 93% coverage of query (610 bits)
PheP / b0576 phenylalanine:H+ symporter PheP from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pheP / P24207 phenylalanine:H+ symporter PheP from Escherichia coli (strain K12) (see 3 papers)
PHEP_ECOLI / P24207 Phenylalanine-specific permease; Phenylalanine:H(+) symporter PheP from Escherichia coli (strain K12) (see 6 papers)
TC 2.A.3.1.1 / P24207 Phenylalanine:H+ symporter, PheP of 458 aas and 12 established TMSs from Escherichia coli (see 6 papers)
59% identity, 96% coverage of query (552 bits)
RR42_RS28305 L-threonine:H+ symporter from Cupriavidus basilensis FW507-4G11
44% identity, 99% coverage of query (395 bits)
AO356_17670 L-alanine and D-alanine permease from Pseudomonas fluorescens FW300-N2C3
45% identity, 98% coverage of query (373 bits)
AO353_16120 D-alanine and L-alanine transporter from Pseudomonas fluorescens FW300-N2E3
46% identity, 98% coverage of query (372 bits)
PS417_05405 L-alanine and D-alanine permease from Pseudomonas simiae WCS417
44% identity, 98% coverage of query (359 bits)
YifK / b3795 putative transporter YifK from Escherichia coli K-12 substr. MG1655 (see 5 papers)
thrP / P27837 threonine/serine:H+ symporter ThrP from Escherichia coli (strain K12) (see 5 papers)
42% identity, 98% coverage of query (351 bits)
DagA / b4208 D-serine/alanine/glycine/:H+symporter from Escherichia coli K-12 substr. MG1655 (see 13 papers)
cycA / P0AAE0 D-serine/alanine/glycine:H+symporter from Escherichia coli (strain K12) (see 15 papers)
CYCA_ECOLI / P0AAE0 D-serine/D-alanine/glycine transporter; Amino acid carrier CycA from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.7 / P0AAE0 D-Serine/D-alanine/glycine/D-cycloserine:H+ symporter from Escherichia coli (see 4 papers)
40% identity, 96% coverage of query (346 bits)
AO353_12275 histidine permease from Pseudomonas fluorescens FW300-N2E3
43% identity, 95% coverage of query (345 bits)
TC 2.A.3.1.6 / P37460 Proline-specific permease (ProY) from Salmonella typhimurium (see 2 papers)
42% identity, 98% coverage of query (344 bits)
CYCA_ECOL6 / A0A0H2VDI7 D-serine/D-alanine/glycine transporter from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see 2 papers)
40% identity, 96% coverage of query (335 bits)
YBXG_BACSU / P54425 Probable threonine/serine transporter YbxG from Bacillus subtilis (strain 168) (see paper)
44% identity, 94% coverage of query (328 bits)
YajM / b0402 putative transporter ProY from Escherichia coli K-12 substr. MG1655 (see 6 papers)
TC 2.A.3.1.23 / P0AAE2 ProY of 457 aas and 12 TMSs from Escherichia coli (strain K12)
41% identity, 98% coverage of query (324 bits)
GABP_BACSU / P46349 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate permease; Gamma-aminobutyrate permease; Proline transporter GabP from Bacillus subtilis (strain 168) (see 3 papers)
TC 2.A.3.1.5 / P46349 β-alanine/γ-aminobutyrate/proline/3,4-dehydroproline:H+ symporter, GabP from Bacillus subtilis (see 4 papers)
gabP / AAC44641.1 gamma-aminobutyrate permease from Bacillus subtilis (see 2 papers)
38% identity, 98% coverage of query (315 bits)
gabP / AAB62306.1 GabP from Bacillus subtilis (see 4 papers)
38% identity, 98% coverage of query (313 bits)
TC 2.A.3.1.17 / M1IW84 D-serine/L-alanine/D-alanine/glycine/D-cycloserine uptake porter of 556 aas, CycA from Mycobacterium bovis BCG str. Korea 1168P
40% identity, 97% coverage of query (307 bits)
AO353_05930 L-tryptophan transporter from Pseudomonas fluorescens FW300-N2E3
37% identity, 97% coverage of query (293 bits)
SERP2_LACLM / A2RI86 DL-alanine permease SerP2 from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
37% identity, 97% coverage of query (291 bits)
ANSP2_MYCTU / P9WQM7 L-asparagine permease 2; L-asparagine transport protein 2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
36% identity, 92% coverage of query (289 bits)
TC 2.A.3.1.21 / F2HQ25 Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM) from Lactococcus lactis subsp. lactis (strain CV56)
39% identity, 84% coverage of query (289 bits)
TC 2.A.3.1.20 / F2HQ24 Serine transporter, SerP2 or YdgB, of 459 aas and 12 TMSs (Trip et al. 2013). Transports L-alanine (Km = 20 μM), D-alanine (Km = 38 μM), L-serine, D-serine (Km = 356 μM) and glycine (Noens and Lolkema 2015). The encoding gene is adjacent to the one encoding SerP1 (TC# 2.A.3.1.21) from Lactococcus lactis subsp. lactis (strain CV56)
37% identity, 98% coverage of query (284 bits)
SERP1_LACLM / A2RI87 Serine permease SerP1 from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
40% identity, 78% coverage of query (284 bits)
YncF / b1453 L-asparagine transporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
ANSP_ECOLI / P77610 L-asparagine permease; L-asparagine transport protein from Escherichia coli (strain K12) (see paper)
TC 2.A.3.1.24 / P77610 Asparagine transporter of 499 aas and 12 TMSs, 91% identical to the orthologue in Salmonella enterica (2.A.3.1.8) from Escherichia coli (strain K12)
35% identity, 97% coverage of query (278 bits)
TC 2.A.3.1.8 / P40812 Asparagine permease (AnsP) of 497 aas and 12 TMSs from Salmonella typhimurium (see 2 papers)
ansP / AAA80001.1 L-asparagine permease from Salmonella enterica (see paper)
37% identity, 87% coverage of query (276 bits)
YVBW_BACSU / O32257 Uncharacterized amino acid permease YvbW from Bacillus subtilis (strain 168)
36% identity, 93% coverage of query (266 bits)
ROCE_BACSU / P39137 Amino-acid permease RocE from Bacillus subtilis (strain 168) (see paper)
TC 2.A.3.1.11 / P39137 L-Arginine permease, RocE from Bacillus subtilis (see 3 papers)
34% identity, 99% coverage of query (266 bits)
GabP / b2663 4-aminobutanoate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 11 papers)
gabP / P25527 4-aminobutanoate:H+ symporter from Escherichia coli (strain K12) (see 10 papers)
GABP_ECOLI / P25527 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate carrier; 4-aminobutyrate permease; Gamma-aminobutyrate permease from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.4 / P25527 γ-aminobutyrate:H+ symporter, GabP. It also transports a variety of pyridine carboxylates. Phosphatidylethanolamine is required for its proper topological organization(Zhang et al. 2005) from Escherichia coli (see 5 papers)
35% identity, 94% coverage of query (259 bits)
MmuP / b0260 CP4-6 prophage; S-methyl-L-methionine transporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
mmuP / Q47689 CP4-6 prophage; S-methyl-L-methionine transporter from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.3.1.10 / Q47689 S-Methylmethionine permease, MmuP from Escherichia coli (see 3 papers)
37% identity, 85% coverage of query (259 bits)
LYSP_LACLM / A2RNZ6 Lysine-specific permease LysP; Lysine transporter LysP from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
37% identity, 86% coverage of query (259 bits)
TC 2.A.3.1.18 / K7VV21 The lysine specific transporter, LysP of 488 aas and 12 TMSs from Lactococcus lactis subsp. cremoris UC509.9
38% identity, 84% coverage of query (258 bits)
AROP_CORGL / Q46065 Aromatic amino acid transport protein AroP; General aromatic amino acid permease from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 2.A.3.1.12 / Q46065 Aromatic amino acid permease, AroP from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
34% identity, 93% coverage of query (256 bits)
BAUD_PSEAE / Q9I703 Probable GABA permease; 4-amino butyrate transport carrier; Gamma-aminobutyrate permease from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
37% identity, 93% coverage of query (252 bits)
HISP_LACLM / A2RI97 Histidine permease HisP from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
36% identity, 87% coverage of query (247 bits)
GAP3_CANAL / A0A1D8PN88 Amino-acid permease GAP3 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 5 papers)
38% identity, 85% coverage of query (247 bits)
CAN1_YEAST / P04817 Arginine permease CAN1; Canavanine resistance protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 12 papers)
TC 2.A.3.10.4 / P04817 Arginine permease from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
CAN1 / RF|NP_010851.1 arginine permease from Saccharomyces cerevisiae
36% identity, 92% coverage of query (245 bits)
CadR / b2156 lysine:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 15 papers)
lysP / P25737 lysine:H+ symporter from Escherichia coli (strain K12) (see 13 papers)
LYSP_ECOLI / P25737 Lysine-specific permease LysP; Lysine transporter LysP; Trigger transporter LysP from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.2 / P25737 Lysine:H+ symporter. Forms a stable complex with CadC to allow lysine-dependent adaptation to acidic stress (Rauschmeier et al. 2013). The Salmonella orthologue is 95% identical to the E. coli protein and is highly specific for Lysine. Residues involved in lysine binding have been identified from Escherichia coli (see 5 papers)
lysP lysine-specific permease from Escherichia coli K12 (see 5 papers)
36% identity, 83% coverage of query (245 bits)
GAP1_CANAL / Q5AG77 Amino-acid permease GAP1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 9 papers)
TC 2.A.3.10.23 / Q5AG77 Amino acid permease, GAP1. Transports Arg, Met, Leu and Phe from Candida albicans (see 2 papers)
GAP1 general amino acid permease from Candida albicans (see 3 papers)
36% identity, 83% coverage of query (234 bits)
CAN1_CANAL / A0A1D8PPI5 Lysine/arginine permease CAN1; Basic amino acids permease CAN1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 7 papers)
35% identity, 91% coverage of query (233 bits)
TC 2.A.3.10.20 / P43059 The high affinity basic amino acid (Arg, Lys, His) transporter, Can1 from Candida albicans (Yeast) (see paper)
34% identity, 95% coverage of query (233 bits)
CAN2_CANAL / Q59WU0 Probable lysine/arginine permease CAN2; Basic amino acids permease CAN2 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 7 papers)
36% identity, 87% coverage of query (232 bits)
LYP1_YEAST / P32487 Lysine-specific permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
TC 2.A.3.10.10 / P32487 Lysine permease of 611 aas and 13 putative TMSs, Lyp1 from Saccharomyces cerevisiae (Baker's yeast) (see 9 papers)
LYP1 / GI|1302328 lysine-specific permease from Saccharomyces cerevisiae
34% identity, 92% coverage of query (232 bits)
agtA amino acid transporter from Emericella nidulans (see 2 papers)
35% identity, 88% coverage of query (231 bits)
CAN1_CANGA / Q6FNY1 Arginine permease CAN1 from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus) (see paper)
35% identity, 91% coverage of query (229 bits)
GAP2_CANAL / A0A1D8PK89 General amino-acid permease GAP2 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 6 papers)
TC 2.A.3.10.24 / Q59YT0 General amino and permease and transceptor, GAP2. Transports all amino acids including citruline and eight tested toxic amino acid derivatives from Candida albicans (see paper)
35% identity, 88% coverage of query (228 bits)
PUT4_SCHPO / Q9URZ3 Probable proline-specific permease put4 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
35% identity, 91% coverage of query (225 bits)
CAN3_CANAL / A0A1D8PPG4 Probable lysine/arginine permease CAN3; Basic amino acids permease CAN3 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 2 papers)
35% identity, 92% coverage of query (224 bits)
PUT4_YEAST / P15380 Proline-specific permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
TC 2.A.3.10.3 / P15380 Proline permease from Saccharomyces cerevisiae (Baker's yeast) (see 4 papers)
PUT4 / RF|NP_014993.1 proline-specific permease from Saccharomyces cerevisiae
34% identity, 91% coverage of query (214 bits)
FYWP_LACLM / A2RMP5 Aromatic amino acid permease FywP from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
38% identity, 76% coverage of query (213 bits)
TC 2.A.3.1.22 / F2HN33 Transporter for phenylalainine, tyrosine and tryptophan of 449 aas and 12 TMSs, FywP or YsjA from Lactococcus lactis subsp. lactis (strain CV56)
37% identity, 76% coverage of query (212 bits)
GAP1_YEAST / P19145 General amino-acid permease GAP1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 19 papers)
TC 2.A.3.10.2 / P19145 General amino acid permease (all L-amino acids and some D-amino acids as well as β-alanine, polyamines and GABA) from Saccharomyces cerevisiae (Baker's yeast) (see 8 papers)
GAP1 / RF|NP_012965.1 general amino-acid permease GAP1 from Saccharomyces cerevisiae
33% identity, 90% coverage of query (209 bits)
GNP1_YEAST / P48813 High-affinity glutamine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
TC 2.A.3.10.5 / P48813 High affinity glutamine permease from Saccharomyces cerevisiae (Baker's yeast) (see 12 papers)
GNP1 / GI|927778 high-affinity glutamine permease from Saccharomyces cerevisiae
32% identity, 86% coverage of query (205 bits)
CAT1_SCHPO / Q9URZ4 Cationic amino acid transporter 1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
33% identity, 88% coverage of query (194 bits)
Build an alignment for AO353_05965 and 56 homologs with ≥ 30% identity
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SSY1_YEAST / Q03770 SPS-sensor component SSY1; Amino-acid permease homolog SSY1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 9 papers)
TC 2.A.3.10.12 / Q03770 Leucine sensor/transcription factor. Mutants hyper- and hyposensitive to inducer (Poulsen et al., 2008) suggest a sensor mechanism involving outward and inward facing conformations from Saccharomyces cerevisiae (Baker's yeast) (see 12 papers)
SSY1 / RF|NP_010444.1 amino-acid permease SSY1 from Saccharomyces cerevisiae (see paper)
26% identity, 88% coverage of query (114 bits)
5j4nA / P60061 Crystal structure of the l-arginine/agmatine antiporter adic in complex with agmatine at 2.6 angstroem resolution (see paper)
23% identity, 81% coverage of query (54.3 bits)
YjdD / b4115 arginine:agmatine antiporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
adiC / P60061 arginine:agmatine antiporter from Escherichia coli (strain K12) (see 2 papers)
ADIC_ECOLI / P60061 Arginine/agmatine antiporter from Escherichia coli (strain K12) (see 6 papers)
ADIC_ECO57 / P60063 Arginine/agmatine antiporter from Escherichia coli O157:H7 (see 3 papers)
TC 2.A.3.2.5 / P60061 Homodimeric electrogenic arginine (Km=80μM):agmatine antiporter, AdiC, involved in extreme acid resistance (Fang et al., 2007; Gong et al., 2003; Iyer et al., 2003). A projection structure at 6.5 Å resolution has been published (Casagrande et al., 2008), and the 3.2 Å resolution X-ray structure was determined by Fang et al., 2009 and Gao et al., 2009 from Escherichia coli (see 6 papers)
adiC / GB|AAN45533.1 arginine/agmatine antiporter from Shigella flexneri (see 6 papers)
23% identity, 81% coverage of query (53.9 bits)
3l1lA Structure of arg-bound escherichia coli adic
22% identity, 81% coverage of query (50.4 bits)
7b00A Human lat2-4f2hc complex in the apo-state
24% identity, 73% coverage of query (50.1 bits)
7cmiB The lat2-4f2hc complex in complex with leucine
24% identity, 73% coverage of query (49.7 bits)
7cmhB / Q9UHI5 The lat2-4f2hc complex in complex with tryptophan (see paper)
24% identity, 73% coverage of query (49.7 bits)
SLC7A8 / Q9UHI5 large neutral amino acids transporter small subunit 2 from Homo sapiens (see 4 papers)
LAT2_HUMAN / Q9UHI5 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; hLAT2; Solute carrier family 7 member 8 from Homo sapiens (Human) (see 14 papers)
TC 2.A.3.8.20 / Q9UHI5 Large neutral amino acids transporter small subunit 2 (L-type amino acid transporter 2) (hLAT2) (Solute carrier family 7 member 8). Certain detergents stabilize and allow purification of the 4F2hc-LAT2 complex, allowing the measurement of substrate binding. In addition, an improved 3D map could be obtained from Homo sapiens (see 12 papers)
24% identity, 73% coverage of query (48.9 bits)
LAT2_MOUSE / Q9QXW9 Large neutral amino acids transporter small subunit 2; L-type amino acid transporter 2; mLAT2; Solute carrier family 7 member 8 from Mus musculus (Mouse) (see 6 papers)
24% identity, 73% coverage of query (47.4 bits)
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Lawrence Berkeley National Laboratory