Searching for up to 100 curated homologs for AO353_09960 FitnessBrowser__pseudo3_N2E3:AO353_09960 (334 a.a.)
Found high-coverage hits (≥70%) to 44 curated proteins.
Removed hits that are identical to the query, leaving 43
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PfGW456L13_740 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens GW456-L13
88% identity, 100% coverage of query (601 bits)
Pf1N1B4_2023 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N1B4
87% identity, 100% coverage of query (598 bits)
AO356_11100 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N2C3
86% identity, 100% coverage of query (583 bits)
Pf6N2E2_4087 L-asparaginase (EC 3.5.1.1) from Pseudomonas fluorescens FW300-N2E2
85% identity, 100% coverage of query (582 bits)
A0A1I0U0N3 asparaginase (EC 3.5.1.1) from Pseudomonas otitidis (see paper)
56% identity, 97% coverage of query (316 bits)
AnsA / b1767 L-asparaginase 1 (EC 3.5.1.38; EC 3.5.1.1) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ansA / P0A962 L-asparaginase 1 (EC 3.5.1.38) from Escherichia coli (strain K12) (see 11 papers)
ASPG1_ECOLI / P0A962 L-asparaginase 1; L-asparaginase I; L-ASNase I; L-asparagine amidohydrolase I; EC 3.5.1.1 from Escherichia coli (strain K12) (see paper)
35% identity, 97% coverage of query (184 bits)
6nxcB / P0A962 Ecai(t162a) mutant in complex with citrate at ph 4 (see paper)
35% identity, 97% coverage of query (174 bits)
2himA Crystal structure and allosteric regulation of the cytoplasmic escherichia coli l-asparaginase i
35% identity, 97% coverage of query (171 bits)
7r6bB / A0A3N4B0Q2 Crystal structure of mutant r43d/l124d/r125a/c273s of l-asparaginase i from yersinia pestis (see paper)
34% identity, 97% coverage of query (165 bits)
CA265_RS25090 L-asparaginase (EC 3.5.1.1) from Pedobacter sp. GW460-11-11-14-LB5
32% identity, 97% coverage of query (164 bits)
W0G253 asparaginase (EC 3.5.1.1) from Rhizomucor miehei (see paper)
35% identity, 98% coverage of query (157 bits)
LPP60_RAT / O88202 60 kDa lysophospholipase; Lysophospholipase-transacylase; EC 3.1.1.5; EC 3.5.1.1; EC 3.1.1.47 from Rattus norvegicus (Rat) (see 3 papers)
32% identity, 100% coverage of query (155 bits)
A0JNU3 1-alkyl-2-acetylglycerophosphocholine esterase (subunit 3/3) (EC 3.1.1.47) from Mus musculus (see paper)
32% identity, 97% coverage of query (154 bits)
ASPG_DIRIM / Q9U518 L-asparaginase; DiAsp; L-asparagine amidohydrolase; EC 3.5.1.1 from Dirofilaria immitis (Canine heartworm) (see paper)
31% identity, 97% coverage of query (150 bits)
ASPG / Q86U10 60 kDa lysophospholipase (EC 3.1.1.47; EC 3.5.1.38) from Homo sapiens (see 4 papers)
34% identity, 97% coverage of query (149 bits)
4r8lA Crystal structure of the asp-bound guinea pig l-asparaginase 1 catalytic domain
33% identity, 97% coverage of query (148 bits)
H0W0T5 asparaginase (EC 3.5.1.1) from Cavia porcellus (see paper)
33% identity, 98% coverage of query (147 bits)
5dndD / H0W0T5 Crystal structure of the asn-bound guinea pig l-asparaginase 1 catalytic domain active site mutant t116a (see paper)
33% identity, 97% coverage of query (146 bits)
ASPG1_BACSU / P26900 L-asparaginase 1; L-ASNase 1; L-asparagine amidohydrolase 1; EC 3.5.1.1 from Bacillus subtilis (strain 168) (see paper)
32% identity, 95% coverage of query (144 bits)
5ot0A / Q5JIW4 The thermostable l-asparaginase from thermococcus kodakarensis (see paper)
34% identity, 81% coverage of query (129 bits)
Build an alignment for AO353_09960 and 20 homologs with ≥ 30% identity
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1zq1A / Q9V0T9 Structure of gatde tRNA-dependent amidotransferase from pyrococcus abyssi (see paper)
29% identity, 98% coverage of query (124 bits)
ASPG_PYRFU / Q8TZE8 L-asparaginase; EC 3.5.1.1 from Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) (see 5 papers)
Q8TZE8 asparaginase (EC 3.5.1.1) from Pyrococcus furiosus (see 2 papers)
30% identity, 81% coverage of query (121 bits)
4q0mA / Q8TZE8 Crystal structure of pyrococcus furiosus l-asparaginase (see paper)
30% identity, 81% coverage of query (121 bits)
gatD / O26802 glutamyl-tRNA(Gln) amidotransferase subunit D (EC 6.3.5.7) from Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H) (see paper)
29% identity, 99% coverage of query (115 bits)
BPHYT_RS08815 L-asparaginase (EC 3.5.1.1) from Burkholderia phytofirmans PsJN
27% identity, 81% coverage of query (68.6 bits)
1hg1A X-ray structure of the complex between erwinia chrysanthemi l-asparaginase and d-aspartate
25% identity, 81% coverage of query (51.6 bits)
ASPG_DICCH / P06608 L-asparaginase; L-ASNase; L-asparagine amidohydrolase; EC 3.5.1.1 from Dickeya chrysanthemi (Pectobacterium chrysanthemi) (Erwinia chrysanthemi) (see 3 papers)
24% identity, 81% coverage of query (50.8 bits)
1jsrA Crystal structure of erwinia chrysanthemi l-asparaginase complexed with 6-hydroxy-l-norleucine
25% identity, 81% coverage of query (49.7 bits)
1jslA Crystal structure of erwinia chrysanthemi l-asparaginase complexed with 6-hydroxy-d-norleucine
25% identity, 81% coverage of query (49.7 bits)
1hg0A X-ray structure of the complex between erwinia chrysanthemi l- asparaginase and succinic acid
25% identity, 81% coverage of query (49.7 bits)
1hfwA X-ray structure of the complex between erwinia chrysanthemi l-asparaginase and l-glutamate
25% identity, 81% coverage of query (49.3 bits)
5k3oA / P50286 Wolinella succinogenes l-asparaginase p121 and l-aspartic acid (see paper)
23% identity, 77% coverage of query (48.9 bits)
5k45A Wolinella succinogenes l-asparaginase p121 + l-glutamic acid
23% identity, 77% coverage of query (48.9 bits)
fraE / Q8ZLD3 N-(1-deoxy-D-fructos-1-yl)-L-asparaginase (EC 3.5.1.1) from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
24% identity, 81% coverage of query (48.5 bits)
A0A2X5A091 asparaginase (EC 3.5.1.1); glutaminase (EC 3.5.1.2) from Helicobacter pylori (see paper)
25% identity, 80% coverage of query (48.5 bits)
7u6mC / P06608 Albumin binding domain fused to a mutant of the erwinia asparaginase (see paper)
24% identity, 81% coverage of query (48.1 bits)
B6ZCD8 asparaginase (EC 3.5.1.1) from Helicobacter pylori (see paper)
I0ZIE0 asparaginase (EC 3.5.1.1) from Helicobacter pylori (see paper)
24% identity, 80% coverage of query (47.0 bits)
2gvnA / I1SBD9 L-asparaginase from erwinia carotovora in complex with aspartic acid (see paper)
23% identity, 82% coverage of query (46.6 bits)
P50286 asparaginase (EC 3.5.1.1) from Wolinella succinogenes (see paper)
23% identity, 78% coverage of query (45.8 bits)
7c8qA Blasnase-t13a with d-asn
24% identity, 91% coverage of query (45.8 bits)
7cbuA Blasnase-t13a with l-asp
25% identity, 75% coverage of query (45.8 bits)
8h4aB / A0A6I7U6Y2 Blasnase-t13a/m57p
25% identity, 75% coverage of query (45.4 bits)
7c8xA Blasnase-t13a with l-asn
25% identity, 75% coverage of query (45.4 bits)
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Lawrence Berkeley National Laboratory