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Searching for up to 100 curated homologs for AO353_17200 FitnessBrowser__pseudo3_N2E3:AO353_17200 (259 a.a.)

Found high-coverage hits (≥70%) to 16 curated proteins.

Removed hits that are identical to the query, leaving 15

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PS417_06705 3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6) from Pseudomonas simiae WCS417
    96% identity, 100% coverage of query (507 bits)

PfGW456L13_4591 3-oxoadipate CoA-transferase subunit B (EC 2.8.3.6) from Pseudomonas fluorescens GW456-L13
    95% identity, 100% coverage of query (501 bits)

CATJ_PSEKB / Q8VPF2 3-oxoadipate CoA-transferase subunit B; 3-oxoadipate:succinyl-CoA transferase subunit B; Beta-ketoadipate:succinyl-CoA transferase subunit B; EC 2.8.3.6 from Pseudomonas knackmussii (strain DSM 6978 / LMG 23759 / B13) (see paper)
Q8VPF2 3-oxoadipate CoA-transferase (subunit 1/2) (EC 2.8.3.6) from Pseudomonas knackmussii (see 2 papers)
    89% identity, 99% coverage of query (468 bits)

gctB / Q59112 GctB (EC 2.8.3.12) from Acidaminococcus fermentans (strain ATCC 25085 / DSM 20731 / CCUG 9996 / CIP 106432 / VR4) (see paper)
Q59112 glutaconate CoA-transferase (subunit 1/2) (EC 2.8.3.12) from Acidaminococcus fermentans (see paper)
    36% identity, 99% coverage of query (154 bits)

Build an alignment

Build an alignment for AO353_17200 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

5mzyB / Q1D4I3 Crystal structure of the decarboxylase aiba/aibb in complex with a possible transition state analog (see paper)
    29% identity, 92% coverage of query (82.0 bits)

5mzzB Crystal structure of the decarboxylase aiba/aibb in complex with 3- methylglutaconate
    29% identity, 92% coverage of query (81.6 bits)

5mzxB Crystal structure of the decarboxylase aiba/aibb in complex with 4'- diphospho pantetheine
    29% identity, 92% coverage of query (81.6 bits)

6cojB / Q0S7Q0 Crystal structure of rhodococcus jostii rha1 ipdab e105a cochea-coa complex (see paper)
    28% identity, 83% coverage of query (69.7 bits)

IPDB_RHOJR / Q0S7Q0 Cholesterol ring-cleaving hydrolase IpdB subunit; (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase beta subunit; COCHEA-CoA hydrolase beta subunit; EC 4.1.99.- from Rhodococcus jostii (strain RHA1) (see 2 papers)
    28% identity, 83% coverage of query (69.7 bits)

ipdB / P9WPV9 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoyl-CoA ligase β subunit from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 6 papers)
IPDB_MYCTU / P9WPV9 Cholesterol ring-cleaving hydrolase IpdB subunit; (3E)-2-(2-carboxylatoethyl)-3-methyl-6-oxocyclohex-1-ene-1-carboxyl-CoA hydrolase beta subunit; COCHEA-CoA hydrolase beta subunit; EC 4.1.99.- from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
    26% identity, 93% coverage of query (68.9 bits)

Pf6N2E2_2112 Dehydrocarnitine CoA-transferase and acetoacetate CoA-transferase, subunit B from Pseudomonas fluorescens FW300-N2E2
    28% identity, 86% coverage of query (63.9 bits)

scoB / P56007 succinyl-CoA-transferase subunit B (EC 2.8.3.5) from Helicobacter pylori (strain ATCC 700392 / 26695) (see paper)
    30% identity, 79% coverage of query (63.2 bits)

Psest_1077 acetyl-CoA:acetoacetate CoA transferase, B subunit (EC 2.8.3.8) from Pseudomonas stutzeri RCH2
    29% identity, 84% coverage of query (53.5 bits)

Sama_1356 3-oxoacid CoA-transferase (EC 2.8.3.5), subunit B from Shewanella amazonensis SB2B
    26% identity, 82% coverage of query (52.8 bits)

pct / G0VND6 propanoyl-CoA transferase monomer (EC 2.8.3.1) from Megasphaera elsdenii DSM 20460 (see 3 papers)
A0A140JTF0 propionate CoA-transferase (EC 2.8.3.1) from Megasphaera elsdenii (see paper)
    25% identity, 82% coverage of query (45.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory