Searching for up to 100 curated homologs for AO353_21365 FitnessBrowser__pseudo3_N2E3:AO353_21365 (336 a.a.)
Found high-coverage hits (≥70%) to 44 curated proteins.
Removed hits that are identical to the query, leaving 43
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
AO356_23190 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas fluorescens FW300-N2C3
97% identity, 100% coverage of query (645 bits)
PS417_11875 Inositol 2-dehydrogenase (EC 1.1.1.18) from Pseudomonas simiae WCS417
92% identity, 100% coverage of query (627 bits)
BWI76_RS03095 Inositol 2-dehydrogenase (EC 1.1.1.18) from Klebsiella michiganensis M5al
75% identity, 100% coverage of query (514 bits)
iolG / A0A0H3FQ94 myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Klebsiella aerogenes (strain ATCC 13048 / DSM 30053 / CCUG 1429 / JCM 1235 / KCTC 2190 / NBRC 13534 / NCIMB 10102 / NCTC 10006 / CDC 819-56) (see 2 papers)
73% identity, 100% coverage of query (509 bits)
iolG / P26935 inositol 2-dehydrogenase monomer (EC 1.1.1.18; EC 1.1.1.369) from Bacillus subtilis (strain 168) (see 5 papers)
IOLG_BACSU / P26935 Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; Myo-inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase; MI 2-dehydrogenase/DCI 3-dehydrogenase; EC 1.1.1.18; EC 1.1.1.369 from Bacillus subtilis (strain 168) (see 3 papers)
P26935 inositol 2-dehydrogenase (EC 1.1.1.18); D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Bacillus subtilis (see 7 papers)
60% identity, 100% coverage of query (445 bits)
3nt5A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor and product inosose
60% identity, 100% coverage of query (444 bits)
3nt4A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor nadh and inositol
60% identity, 100% coverage of query (444 bits)
3nt2B Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor
60% identity, 100% coverage of query (444 bits)
3nt2A Crystal structure of myo-inositol dehydrogenase from bacillus subtilis with bound cofactor
60% identity, 100% coverage of query (444 bits)
4l8vA / P26935 Crystal structure of a12k/d35s mutant myo-inositol dehydrogenase from bacillus subtilis with bound cofactor NADP (see paper)
60% identity, 100% coverage of query (441 bits)
3ec7A / Q8ZK57 Crystal structure of putative dehydrogenase from salmonella typhimurium lt2
51% identity, 100% coverage of query (357 bits)
E1U887 inositol 2-dehydrogenase (EC 1.1.1.18) from Lacticaseibacillus casei (see paper)
47% identity, 100% coverage of query (314 bits)
4minA / A0A0J9X1Y2 Crystal structure of myo-inositol dehydrogenase from lactobacillus casei with bound cofactor NAD
47% identity, 100% coverage of query (313 bits)
4mjlD Crystal structure of myo-inositol dehydrogenase from lactobacillus casei in complex with NAD and d-chiro-inositol
47% identity, 100% coverage of query (313 bits)
4mioD Crystal structure of myo-inositol dehydrogenase from lactobacillus casei in complex with NAD(h) and myo-inositol
47% identity, 100% coverage of query (313 bits)
4mioA Crystal structure of myo-inositol dehydrogenase from lactobacillus casei in complex with NAD(h) and myo-inositol
47% identity, 100% coverage of query (313 bits)
Q8NTY7 inositol 2-dehydrogenase (EC 1.1.1.18) from Corynebacterium glutamicum (see paper)
40% identity, 99% coverage of query (231 bits)
Build an alignment for AO353_21365 and 17 homologs with ≥ 30% identity
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4n54A / A0A0J9X1Y7 Crystal structure of scyllo-inositol dehydrogenase from lactobacillus casei with bound cofactor NAD(h) and scyllo-inositol
26% identity, 97% coverage of query (125 bits)
E1U888 inositol 2-dehydrogenase (EC 1.1.1.18) from Lacticaseibacillus casei (see paper)
26% identity, 98% coverage of query (125 bits)
3ceaA / F9ULF9 Crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from lactobacillus plantarum at 2.40 a resolution
26% identity, 97% coverage of query (120 bits)
iolG / Q9WYP5 myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
IOLG_THEMA / Q9WYP5 Myo-inositol 2-dehydrogenase; EC 1.1.1.18 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9WYP5 D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Thermotoga maritima (see paper)
27% identity, 95% coverage of query (114 bits)
iolX / P40332 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Bacillus subtilis (strain 168) (see paper)
IOLX_BACSU / P40332 scyllo-inositol 2-dehydrogenase (NAD(+)); EC 1.1.1.370 from Bacillus subtilis (strain 168) (see paper)
P40332 scyllo-inositol 2-dehydrogenase (NAD+) (EC 1.1.1.370) from Bacillus subtilis (see 2 papers)
28% identity, 88% coverage of query (107 bits)
HSERO_RS12095 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Herbaspirillum seropedicae SmR1
27% identity, 97% coverage of query (103 bits)
SM_b20899 Inositol 2-dehydrogenase (EC 1.1.1.18) from Sinorhizobium meliloti 1021
MI2D_RHIME / O68965 Inositol 2-dehydrogenase; Myo-inositol 2-dehydrogenase; MI-dehydrogenase; EC 1.1.1.18 from Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
O68965 inositol 2-dehydrogenase (EC 1.1.1.18) from Sinorhizobium meliloti (see paper)
29% identity, 90% coverage of query (101 bits)
Q9EZV8 inositol 2-dehydrogenase (EC 1.1.1.18) from Sinorhizobium fredii (see paper)
28% identity, 90% coverage of query (97.4 bits)
mocA / GB|CAA55269.1 rhizopine catabolism protein MocA from Sinorhizobium meliloti (see paper)
27% identity, 93% coverage of query (88.2 bits)
6jw7A / Q6L737 The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin a (see paper)
27% identity, 73% coverage of query (70.5 bits)
6jw6A The crystal structure of kand2 in complex with NAD
27% identity, 73% coverage of query (70.5 bits)
6jw8A The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin b
27% identity, 73% coverage of query (70.5 bits)
3e18A / Q929L3 Crystal structure of NAD-binding protein from listeria innocua
26% identity, 77% coverage of query (68.2 bits)
7x2yA / A0A076PYH9 Crystal structure of cis-4,5-dihydrodiol phthalate dehydrogenase in complex with NAD+ and 3-hydroxybenzoate (see paper)
25% identity, 73% coverage of query (61.6 bits)
DHDH_RABIT / Q9TV70 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; Ory2DD; EC 1.3.1.20; EC 1.1.1.179 from Oryctolagus cuniculus (Rabbit) (see 2 papers)
30% identity, 74% coverage of query (60.8 bits)
ntdC / O07564 glucose-6-phosphate 3-dehydrogenase (EC 1.1.1.361) from Bacillus subtilis (strain 168) (see 4 papers)
NTDC_BACSU / O07564 Glucose-6-phosphate 3-dehydrogenase; EC 1.1.1.361 from Bacillus subtilis (strain 168) (see 3 papers)
O07564 glucose-6-phosphate 3-dehydrogenase (EC 1.1.1.361) from Bacillus subtilis (see 2 papers)
23% identity, 90% coverage of query (58.9 bits)
UGNO_METMP / Q6M0B9 UDP-N-acetylglucosamine 3-dehydrogenase; UDP-GlcNAc oxidoreductase; UDP-N-acetyl-alpha-D-glucosamine:NAD(+) 3-oxidoreductase; EC 1.1.1.374 from Methanococcus maripaludis (strain S2 / LL) (see paper)
Q6M0B9 UDP-N-acetylglucosamine 3-dehydrogenase (EC 1.1.1.374) from Methanococcus maripaludis (see paper)
24% identity, 75% coverage of query (57.8 bits)
apsD / B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium radiobacter (strain K84 / ATCC BAA-868) (see paper)
APSD_RHIR8 / B9JK80 D-apiose dehydrogenase; EC 1.1.1.420 from Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter) (see paper)
B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium tumefaciens (see paper)
23% identity, 97% coverage of query (54.7 bits)
5uhwA / B9JK80 Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+ and magnesium
23% identity, 97% coverage of query (54.7 bits)
5uiaA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, r-2,3-dihydroxyisovalerate and magnesium
23% identity, 97% coverage of query (54.7 bits)
5ui9A Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, 2 -hydroxy-2-hydroxymethyl propanoic acid and magnesium
23% identity, 97% coverage of query (54.7 bits)
5uhzA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, d-apionate and magnesium
23% identity, 97% coverage of query (54.7 bits)
APSD_PARG4 / B1G894 D-apiose dehydrogenase; EC 1.1.1.420 from Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) (see paper)
24% identity, 72% coverage of query (54.3 bits)
D4GR07 L-arabinose 1-dehydrogenase [NAD(P)+] (EC 1.1.1.376) from Haloferax volcanii (see paper)
25% identity, 73% coverage of query (50.8 bits)
KIJDR_ACTKI / B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase; 3-ketoreductase; NADPH-dependent C3-ketoreductase; EC 1.1.1.384 from Actinomadura kijaniata (see paper)
B3TMR8 dTDP-3,4-didehydro-2,6-dideoxy-alpha-D-glucose 3-reductase (EC 1.1.1.384) from Actinomadura kijaniata (see paper)
23% identity, 73% coverage of query (43.1 bits)
3rc1A / B3TMR8 Crystal structure of kijd10, a 3-ketoreductase from actinomadura kijaniata incomplex with NADP and tdp-benzene (see paper)
23% identity, 73% coverage of query (43.1 bits)
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Lawrence Berkeley National Laboratory