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Searching for up to 100 curated homologs for AO353_24320 FitnessBrowser__pseudo3_N2E3:AO353_24320 (294 a.a.)

Found high-coverage hits (≥70%) to 25 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

4yskA / A5VWI3 Crystal structure of apo-form sdoa from pseudomonas putida (see paper)
    62% identity, 100% coverage of query (402 bits)

4yslA Crystal structure of sdoa from pseudomonas putida in complex with glutathione
    62% identity, 100% coverage of query (402 bits)

4efzA / Q3JRV4 Crystal structure of a hypothetical metallo-beta-lactamase from burkholderia pseudomallei
    59% identity, 98% coverage of query (376 bits)

blhA / CBY83975.1 metallo-beta-lactamase family from Serratia sp. ATCC 39006 (see paper)
    53% identity, 97% coverage of query (318 bits)

BLH_XYLFA / Q9PFB0 Beta-lactamase hydrolase-like protein; BLH; EC 3.-.-.- from Xylella fastidiosa (strain 9a5c) (see paper)
    51% identity, 97% coverage of query (295 bits)

BLH_AGRFC / Q8UAA9 Beta-lactamase hydrolase-like protein; BLH; EC 3.-.-.- from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
    50% identity, 97% coverage of query (281 bits)

ETHE1 / O95571 mitochondrial persulfide dioxygenase monomer (EC 1.13.11.18) from Homo sapiens (see 6 papers)
ETHE1_HUMAN / O95571 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Homo sapiens (Human) (see 6 papers)
    33% identity, 92% coverage of query (115 bits)

5ve5A / B2TEQ2 Crystal structure of persulfide dioxygenase rhodanese fusion protein with rhodanese domain inactivating mutation (c314s) from burkholderia phytofirmans in complex with glutathione (see paper)
    31% identity, 93% coverage of query (115 bits)

4chlB / O95571 Human ethylmalonic encephalopathy protein 1 (hethe1) (see paper)
    33% identity, 91% coverage of query (114 bits)

ETHE1_MOUSE / Q9DCM0 Persulfide dioxygenase ETHE1, mitochondrial; Ethylmalonic encephalopathy protein 1 homolog; Hepatoma subtracted clone one protein; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Mus musculus (Mouse) (see paper)
    30% identity, 94% coverage of query (113 bits)

4ysbA / Q1D4C9 Crystal structure of ethe1 from myxococcus xanthus (see paper)
    30% identity, 91% coverage of query (110 bits)

Build an alignment

Build an alignment for AO353_24320 and 11 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

sdo / B7J413 sulfur dioxygenase α subunit (EC 1.13.11.18) from Acidithiobacillus ferrooxidans (strain ATCC 23270 / DSM 14882 / CIP 104768 / NCIMB 8455) (see 4 papers)
B7J413 persulfide dioxygenase (EC 1.13.11.18) from Acidithiobacillus ferrooxidans (see paper)
    29% identity, 92% coverage of query (100 bits)

ETHE1_ARATH / Q9C8L4 Persulfide dioxygenase ETHE1 homolog, mitochondrial; Glyoxalase II; Glx II; Sulfur dioxygenase ETHE1; EC 1.13.11.18 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
Q9C8L4 persulfide dioxygenase (EC 1.13.11.18) from Arabidopsis thaliana (see paper)
    29% identity, 91% coverage of query (98.2 bits)

2gcuA / Q9C8L4 X-ray structure of gene product from arabidopsis thaliana at1g53580 (see paper)
    29% identity, 91% coverage of query (97.4 bits)

3r2uB 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
    26% identity, 94% coverage of query (79.7 bits)

3tp9A / C8WS08 Crystal structure of alicyclobacillus acidocaldarius protein with beta-lactamase and rhodanese domains
    28% identity, 82% coverage of query (78.2 bits)

3r2uA / A0A0H2X0Y8 2.1 angstrom resolution crystal structure of metallo-beta-lactamase from staphylococcus aureus subsp. Aureus col
    25% identity, 94% coverage of query (76.3 bits)

GLO2C_ARATH / O24496 Hydroxyacylglutathione hydrolase cytoplasmic; Glyoxalase II; Glx II; EC 3.1.2.6 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    26% identity, 94% coverage of query (70.1 bits)

G5ELA4 persulfide dioxygenase (EC 1.13.11.18) from Staphylococcus aureus (see paper)
    24% identity, 74% coverage of query (65.9 bits)

BAEB_BACVZ / A7Z4X7 Probable polyketide biosynthesis zinc-dependent hydrolase BaeB; EC 3.-.-.- from Bacillus velezensis (strain DSM 23117 / BGSC 10A6 / LMG 26770 / FZB42) (Bacillus amyloliquefaciens subsp. plantarum) (see paper)
    25% identity, 82% coverage of query (64.7 bits)

1qh3A / Q16775 Human glyoxalase ii with cacodylate and acetate ions present in the active site (see paper)
    25% identity, 72% coverage of query (58.5 bits)

GLO2_HUMAN / Q16775 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; EC 3.1.2.6 from Homo sapiens (Human) (see 3 papers)
Q16775 hydroxyacylglutathione hydrolase (EC 3.1.2.6) from Homo sapiens (see 8 papers)
    25% identity, 72% coverage of query (58.5 bits)

1qh5B Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione
    25% identity, 72% coverage of query (58.5 bits)

1qh5A Human glyoxalase ii with s-(n-hydroxy-n-bromophenylcarbamoyl) glutathione
    25% identity, 72% coverage of query (58.5 bits)

GLO2_RAT / O35952 Hydroxyacylglutathione hydrolase, mitochondrial; Glyoxalase II; Glx II; Round spermatid protein RSP29; EC 3.1.2.6 from Rattus norvegicus (Rat) (see 2 papers)
O35952 hydroxyacylglutathione hydrolase (EC 3.1.2.6) from Rattus norvegicus (see paper)
    24% identity, 72% coverage of query (57.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory