Searching for up to 100 curated homologs for AO353_24335 FitnessBrowser__pseudo3_N2E3:AO353_24335 (494 a.a.)
Found high-coverage hits (≥70%) to 55 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 2.A.3.1.8 / P40812 Asparagine permease (AnsP) of 497 aas and 12 TMSs from Salmonella typhimurium (see 2 papers)
ansP / AAA80001.1 L-asparagine permease from Salmonella enterica (see paper)
66% identity, 96% coverage of query (635 bits)
YncF / b1453 L-asparagine transporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
ANSP_ECOLI / P77610 L-asparagine permease; L-asparagine transport protein from Escherichia coli (strain K12) (see paper)
TC 2.A.3.1.24 / P77610 Asparagine transporter of 499 aas and 12 TMSs, 91% identical to the orthologue in Salmonella enterica (2.A.3.1.8) from Escherichia coli (strain K12)
67% identity, 91% coverage of query (629 bits)
ANSP2_MYCTU / P9WQM7 L-asparagine permease 2; L-asparagine transport protein 2 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
55% identity, 90% coverage of query (487 bits)
RR42_RS28305 L-threonine:H+ symporter from Cupriavidus basilensis FW507-4G11
46% identity, 85% coverage of query (389 bits)
TC 2.A.3.1.6 / P37460 Proline-specific permease (ProY) from Salmonella typhimurium (see 2 papers)
39% identity, 85% coverage of query (317 bits)
AO356_17670 L-alanine and D-alanine permease from Pseudomonas fluorescens FW300-N2C3
40% identity, 85% coverage of query (316 bits)
RR42_RS33495 L-phenylalanine:H+ symporter AroP from Cupriavidus basilensis FW507-4G11
38% identity, 96% coverage of query (312 bits)
H281DRAFT_04042 phenylacetate transporter from Paraburkholderia bryophila 376MFSha3.1
39% identity, 87% coverage of query (311 bits)
AO353_16120 D-alanine and L-alanine transporter from Pseudomonas fluorescens FW300-N2E3
41% identity, 85% coverage of query (309 bits)
AroR / b0112 aromatic amino acid:H+ symporter AroP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
aroP / P15993 aromatic amino acid:H+ symporter AroP from Escherichia coli (strain K12) (see 6 papers)
AROP_ECOLI / P15993 Aromatic amino acid transport protein AroP; Aromatic amino acid:H(+) symporter AroP; General aromatic amino acid permease; General aromatic transport system from Escherichia coli (strain K12) (see 8 papers)
TC 2.A.3.1.3 / P15993 Aromatic amino acid:H+ symporter, AroP of 457 aas and 12 TMSs (Cosgriff and Pittard 1997). Transports phenylalanine, tyrosine and tryptophan from Escherichia coli (see 6 papers)
38% identity, 88% coverage of query (308 bits)
PheP / b0576 phenylalanine:H+ symporter PheP from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pheP / P24207 phenylalanine:H+ symporter PheP from Escherichia coli (strain K12) (see 3 papers)
PHEP_ECOLI / P24207 Phenylalanine-specific permease; Phenylalanine:H(+) symporter PheP from Escherichia coli (strain K12) (see 6 papers)
TC 2.A.3.1.1 / P24207 Phenylalanine:H+ symporter, PheP of 458 aas and 12 established TMSs from Escherichia coli (see 6 papers)
39% identity, 85% coverage of query (306 bits)
PS417_05405 L-alanine and D-alanine permease from Pseudomonas simiae WCS417
41% identity, 85% coverage of query (304 bits)
YajM / b0402 putative transporter ProY from Escherichia coli K-12 substr. MG1655 (see 6 papers)
TC 2.A.3.1.23 / P0AAE2 ProY of 457 aas and 12 TMSs from Escherichia coli (strain K12)
38% identity, 92% coverage of query (302 bits)
AO356_18530 L-tyrosine transporter from Pseudomonas fluorescens FW300-N2C3
36% identity, 88% coverage of query (298 bits)
PfGW456L13_4291 L-tryptophan transporter from Pseudomonas fluorescens GW456-L13
37% identity, 87% coverage of query (295 bits)
GABP_BACSU / P46349 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate permease; Gamma-aminobutyrate permease; Proline transporter GabP from Bacillus subtilis (strain 168) (see 3 papers)
TC 2.A.3.1.5 / P46349 β-alanine/γ-aminobutyrate/proline/3,4-dehydroproline:H+ symporter, GabP from Bacillus subtilis (see 4 papers)
gabP / AAC44641.1 gamma-aminobutyrate permease from Bacillus subtilis (see 2 papers)
37% identity, 94% coverage of query (292 bits)
gabP / AAB62306.1 GabP from Bacillus subtilis (see 4 papers)
37% identity, 94% coverage of query (291 bits)
YBXG_BACSU / P54425 Probable threonine/serine transporter YbxG from Bacillus subtilis (strain 168) (see paper)
39% identity, 84% coverage of query (290 bits)
DagA / b4208 D-serine/alanine/glycine/:H+symporter from Escherichia coli K-12 substr. MG1655 (see 13 papers)
cycA / P0AAE0 D-serine/alanine/glycine:H+symporter from Escherichia coli (strain K12) (see 15 papers)
CYCA_ECOLI / P0AAE0 D-serine/D-alanine/glycine transporter; Amino acid carrier CycA from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.7 / P0AAE0 D-Serine/D-alanine/glycine/D-cycloserine:H+ symporter from Escherichia coli (see 4 papers)
37% identity, 90% coverage of query (288 bits)
AO353_12275 histidine permease from Pseudomonas fluorescens FW300-N2E3
36% identity, 94% coverage of query (287 bits)
TC 2.A.3.1.17 / M1IW84 D-serine/L-alanine/D-alanine/glycine/D-cycloserine uptake porter of 556 aas, CycA from Mycobacterium bovis BCG str. Korea 1168P
40% identity, 83% coverage of query (282 bits)
CYCA_ECOL6 / A0A0H2VDI7 D-serine/D-alanine/glycine transporter from Escherichia coli O6:H1 (strain CFT073 / ATCC 700928 / UPEC) (see 2 papers)
37% identity, 90% coverage of query (278 bits)
YifK / b3795 putative transporter YifK from Escherichia coli K-12 substr. MG1655 (see 5 papers)
thrP / P27837 threonine/serine:H+ symporter ThrP from Escherichia coli (strain K12) (see 5 papers)
36% identity, 86% coverage of query (276 bits)
LYSP_LACLM / A2RNZ6 Lysine-specific permease LysP; Lysine transporter LysP from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
37% identity, 87% coverage of query (263 bits)
AO353_05930 L-tryptophan transporter from Pseudomonas fluorescens FW300-N2E3
33% identity, 89% coverage of query (261 bits)
TC 2.A.3.1.18 / K7VV21 The lysine specific transporter, LysP of 488 aas and 12 TMSs from Lactococcus lactis subsp. cremoris UC509.9
37% identity, 87% coverage of query (257 bits)
MmuP / b0260 CP4-6 prophage; S-methyl-L-methionine transporter from Escherichia coli K-12 substr. MG1655 (see 3 papers)
mmuP / Q47689 CP4-6 prophage; S-methyl-L-methionine transporter from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.3.1.10 / Q47689 S-Methylmethionine permease, MmuP from Escherichia coli (see 3 papers)
33% identity, 95% coverage of query (251 bits)
ROCE_BACSU / P39137 Amino-acid permease RocE from Bacillus subtilis (strain 168) (see paper)
TC 2.A.3.1.11 / P39137 L-Arginine permease, RocE from Bacillus subtilis (see 3 papers)
35% identity, 87% coverage of query (241 bits)
CadR / b2156 lysine:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 15 papers)
lysP / P25737 lysine:H+ symporter from Escherichia coli (strain K12) (see 13 papers)
LYSP_ECOLI / P25737 Lysine-specific permease LysP; Lysine transporter LysP; Trigger transporter LysP from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.2 / P25737 Lysine:H+ symporter. Forms a stable complex with CadC to allow lysine-dependent adaptation to acidic stress (Rauschmeier et al. 2013). The Salmonella orthologue is 95% identical to the E. coli protein and is highly specific for Lysine. Residues involved in lysine binding have been identified from Escherichia coli (see 5 papers)
lysP lysine-specific permease from Escherichia coli K12 (see 5 papers)
34% identity, 86% coverage of query (238 bits)
YVBW_BACSU / O32257 Uncharacterized amino acid permease YvbW from Bacillus subtilis (strain 168)
33% identity, 85% coverage of query (237 bits)
TC 2.A.3.1.21 / F2HQ25 Serine uptake transporter, SerP1, of 259 aas and 12 TMSs (Trip et al. 2013). L-serine is the highest affinity substrate (Km = 18 μM), but SerP1 also transports L-threonine and L-cysteine (Km values = 20 - 40 μM) from Lactococcus lactis subsp. lactis (strain CV56)
36% identity, 73% coverage of query (234 bits)
AROP_CORGL / Q46065 Aromatic amino acid transport protein AroP; General aromatic amino acid permease from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
TC 2.A.3.1.12 / Q46065 Aromatic amino acid permease, AroP from Corynebacterium glutamicum (Brevibacterium flavum) (see 2 papers)
34% identity, 93% coverage of query (232 bits)
GabP / b2663 4-aminobutanoate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 11 papers)
gabP / P25527 4-aminobutanoate:H+ symporter from Escherichia coli (strain K12) (see 10 papers)
GABP_ECOLI / P25527 Gamma-aminobutyric acid permease; GABA permease; 4-aminobutyrate carrier; 4-aminobutyrate permease; Gamma-aminobutyrate permease from Escherichia coli (strain K12) (see 7 papers)
TC 2.A.3.1.4 / P25527 γ-aminobutyrate:H+ symporter, GabP. It also transports a variety of pyridine carboxylates. Phosphatidylethanolamine is required for its proper topological organization(Zhang et al. 2005) from Escherichia coli (see 5 papers)
33% identity, 89% coverage of query (231 bits)
SERP1_LACLM / A2RI87 Serine permease SerP1 from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
35% identity, 72% coverage of query (231 bits)
HISP_LACLM / A2RI97 Histidine permease HisP from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
35% identity, 82% coverage of query (226 bits)
GAP2_CANAL / A0A1D8PK89 General amino-acid permease GAP2 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 6 papers)
TC 2.A.3.10.24 / Q59YT0 General amino and permease and transceptor, GAP2. Transports all amino acids including citruline and eight tested toxic amino acid derivatives from Candida albicans (see paper)
36% identity, 78% coverage of query (217 bits)
SERP2_LACLM / A2RI86 DL-alanine permease SerP2 from Lactococcus lactis subsp. cremoris (strain MG1363) (see 2 papers)
32% identity, 83% coverage of query (215 bits)
TC 2.A.3.1.20 / F2HQ24 Serine transporter, SerP2 or YdgB, of 459 aas and 12 TMSs (Trip et al. 2013). Transports L-alanine (Km = 20 μM), D-alanine (Km = 38 μM), L-serine, D-serine (Km = 356 μM) and glycine (Noens and Lolkema 2015). The encoding gene is adjacent to the one encoding SerP1 (TC# 2.A.3.1.21) from Lactococcus lactis subsp. lactis (strain CV56)
33% identity, 82% coverage of query (215 bits)
LYP1_YEAST / P32487 Lysine-specific permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 2 papers)
TC 2.A.3.10.10 / P32487 Lysine permease of 611 aas and 13 putative TMSs, Lyp1 from Saccharomyces cerevisiae (Baker's yeast) (see 9 papers)
LYP1 / GI|1302328 lysine-specific permease from Saccharomyces cerevisiae
32% identity, 90% coverage of query (214 bits)
CAN1_CANGA / Q6FNY1 Arginine permease CAN1 from Candida glabrata (strain ATCC 2001 / BCRC 20586 / JCM 3761 / NBRC 0622 / NRRL Y-65 / CBS 138) (Yeast) (Nakaseomyces glabratus) (see paper)
34% identity, 85% coverage of query (207 bits)
BAUD_PSEAE / Q9I703 Probable GABA permease; 4-amino butyrate transport carrier; Gamma-aminobutyrate permease from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
32% identity, 89% coverage of query (207 bits)
CAN1_YEAST / P04817 Arginine permease CAN1; Canavanine resistance protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 12 papers)
TC 2.A.3.10.4 / P04817 Arginine permease from Saccharomyces cerevisiae (Baker's yeast) (see 6 papers)
CAN1 / RF|NP_010851.1 arginine permease from Saccharomyces cerevisiae
31% identity, 84% coverage of query (205 bits)
GAP1_CANAL / Q5AG77 Amino-acid permease GAP1 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 9 papers)
TC 2.A.3.10.23 / Q5AG77 Amino acid permease, GAP1. Transports Arg, Met, Leu and Phe from Candida albicans (see 2 papers)
GAP1 general amino acid permease from Candida albicans (see 3 papers)
36% identity, 81% coverage of query (204 bits)
GAP3_CANAL / A0A1D8PN88 Amino-acid permease GAP3 from Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast) (see 5 papers)
30% identity, 85% coverage of query (194 bits)
YQD2_SCHPO / Q9C0V0 Probable amino-acid permease PB1C11.02 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
30% identity, 91% coverage of query (193 bits)
AAT1_SCHPO / Q9P5N2 Amino acid transporter 1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
33% identity, 78% coverage of query (192 bits)
TC 2.A.3.10.28 / O60170 Probable amino-acid permease Meu22 (Meiotic expression up-regulated protein 22) from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (see 2 papers)
32% identity, 79% coverage of query (190 bits)
GAP1_YEAST / P19145 General amino-acid permease GAP1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 19 papers)
TC 2.A.3.10.2 / P19145 General amino acid permease (all L-amino acids and some D-amino acids as well as β-alanine, polyamines and GABA) from Saccharomyces cerevisiae (Baker's yeast) (see 8 papers)
GAP1 / RF|NP_012965.1 general amino-acid permease GAP1 from Saccharomyces cerevisiae
32% identity, 88% coverage of query (189 bits)
YI26_SCHPO / Q9P768 Uncharacterized amino-acid permease P7G5.06 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
per1 plasma membrane amino acid permease Per1 from Schizosaccharomyces pombe (see 2 papers)
31% identity, 83% coverage of query (188 bits)
CAT1_SCHPO / Q9URZ4 Cationic amino acid transporter 1 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
32% identity, 77% coverage of query (187 bits)
Build an alignment for AO353_24335 and 50 homologs with ≥ 30% identity
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GNP1_YEAST / P48813 High-affinity glutamine permease from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
TC 2.A.3.10.5 / P48813 High affinity glutamine permease from Saccharomyces cerevisiae (Baker's yeast) (see 12 papers)
GNP1 / GI|927778 high-affinity glutamine permease from Saccharomyces cerevisiae
28% identity, 82% coverage of query (154 bits)
SSY1_YEAST / Q03770 SPS-sensor component SSY1; Amino-acid permease homolog SSY1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 9 papers)
TC 2.A.3.10.12 / Q03770 Leucine sensor/transcription factor. Mutants hyper- and hyposensitive to inducer (Poulsen et al., 2008) suggest a sensor mechanism involving outward and inward facing conformations from Saccharomyces cerevisiae (Baker's yeast) (see 12 papers)
SSY1 / RF|NP_010444.1 amino-acid permease SSY1 from Saccharomyces cerevisiae (see paper)
22% identity, 90% coverage of query (79.0 bits)
CTR1_HUMAN / P30825 High affinity cationic amino acid transporter 1; CAT-1; CAT1; Ecotropic retroviral leukemia receptor homolog; Ecotropic retrovirus receptor homolog; Solute carrier family 7 member 1; System Y+ basic amino acid transporter from Homo sapiens (Human) (see 4 papers)
TC 2.A.3.3.9 / P30825 High affinity cationic amino acid transporter 1 (CAT-1) (CAT1) (Ecotropic retroviral leukemia receptor homologue) (Ecotropic retrovirus receptor homologue) (ERR) (Solute carrier family 7 member 1) (System Y+ basic amino acid transporter) from Homo sapiens (see 6 papers)
21% identity, 76% coverage of query (55.1 bits)
6f34A / Q5L1G5 Crystal structure of a bacterial cationic amino acid transporter (cat) homologue bound to arginine. (see paper)
22% identity, 76% coverage of query (49.7 bits)
5oqtA Crystal structure of a bacterial cationic amino acid transporter (cat) homologue
23% identity, 76% coverage of query (48.9 bits)
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Lawrence Berkeley National Laboratory