Searching for up to 100 curated homologs for AO353_24515 FitnessBrowser__pseudo3_N2E3:AO353_24515 (432 a.a.)
Found high-coverage hits (≥70%) to 47 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
NICT_PSEPK / Q88FY6 Putative metabolite transport protein NicT; Nicotinate degradation protein T from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see paper)
50% identity, 96% coverage of query (413 bits)
TC 2.A.1.14.8 / Q9RPP3 Phthalate porter from Burkholderia cepacia (Pseudomonas cepacia) (see paper)
42% identity, 97% coverage of query (342 bits)
ABAQ_ACIBT / P0DPR4 Quinolone resistance transporter from Acinetobacter baumannii (strain ATCC 17978 / CIP 53.77 / LMG 1025 / NCDC KC755 / 5377) (see 2 papers)
39% identity, 95% coverage of query (307 bits)
PS417_07265 2-deoxy-D-ribonate transporter 1 from Pseudomonas simiae WCS417
39% identity, 90% coverage of query (268 bits)
YfaV / b2246 putative transporter YfaV from Escherichia coli K-12 substr. MG1655 (see 4 papers)
TC 2.A.1.14.35 / P76470 Inner membrane transport protein RhmT from Escherichia coli (strain K12) (see 4 papers)
36% identity, 100% coverage of query (257 bits)
BWI76_RS23715 2-deoxy-D-ribonate transporter 1 from Klebsiella michiganensis M5al
35% identity, 97% coverage of query (246 bits)
BPHYT_RS04765 2-deoxy-D-ribonate transporter from Burkholderia phytofirmans PsJN
36% identity, 96% coverage of query (232 bits)
H281DRAFT_00642 2-deoxy-D-ribonate transporter from Paraburkholderia bryophila 376MFSha3.1
36% identity, 96% coverage of query (228 bits)
Build an alignment for AO353_24515 and 8 homologs with ≥ 30% identity
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CH_124132 transporter of Nicotinic Acid from Magnaporthe grisea 70-15 (see paper)
29% identity, 87% coverage of query (157 bits)
CH_124029 high-affinity nicotinic acid transporter from Magnaporthe grisea 70-15 (see paper)
27% identity, 87% coverage of query (144 bits)
CH_124128 MFS transporter from Magnaporthe grisea 70-15 (see paper)
29% identity, 73% coverage of query (142 bits)
orf19.3232 putative transporter from Candida albicans (see paper)
26% identity, 90% coverage of query (141 bits)
CH_124317 phthalate transporter from Magnaporthe grisea 70-15 (see paper)
29% identity, 90% coverage of query (137 bits)
CH_124318 MFS transporter from Magnaporthe grisea 70-15 (see 2 papers)
29% identity, 86% coverage of query (130 bits)
CH_124319 high-affinity nicotinic acid transporter from Magnaporthe grisea 70-15 (see paper)
28% identity, 87% coverage of query (127 bits)
TNA1 putative nicotinic acid transporter from Candida albicans (see paper)
25% identity, 78% coverage of query (119 bits)
YIZG_SCHPO / Q9US44 Uncharacterized transporter C1002.16c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
28% identity, 75% coverage of query (114 bits)
CH_124204 putative monocarboxylate exporter from Magnaporthe grisea 70-15 (see paper)
23% identity, 87% coverage of query (103 bits)
GUDP_BACSU / P42237 Probable galactarate/D-glucarate transporter GudP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.14.1 / P42237 Glucarate porter from Bacillus subtilis (see 3 papers)
24% identity, 90% coverage of query (97.1 bits)
SAUU_CUPNH / Q0K843 Probable sulfoacetate transporter SauU from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
23% identity, 92% coverage of query (94.0 bits)
PS417_04205 D-galacturonate transporter (MFS superfamily) from Pseudomonas simiae WCS417
24% identity, 90% coverage of query (88.6 bits)
HXNP_EMENI / C8VJW1 Major facilitator-type transporter hxnP; Nicotinate catabolism cluster protein hxnP from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
26% identity, 77% coverage of query (87.4 bits)
GudP / b2789 galactarate/D-glucarate transporter GudP from Escherichia coli K-12 substr. MG1655 (see 5 papers)
gudP / Q46916 galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 5 papers)
GUDP_ECOLI / Q46916 Probable galactarate/D-glucarate transporter GudP from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.14.40 / C4ZZU4 Glucarate transporter, GudP. Encoded in an operon with GudD, a glucarate dehydratase from Escherichia coli (strain K12 / MC4100 / BW2952)
22% identity, 92% coverage of query (80.1 bits)
CH_124130 conserved hypothetical protein from Magnaporthe grisea 70-15 (see paper)
24% identity, 72% coverage of query (78.2 bits)
CH_124316 allantoate permease from Magnaporthe grisea 70-15 (see paper)
23% identity, 72% coverage of query (77.8 bits)
FEN2_YEAST / P25621 Pantothenate transporter FEN2; Fenpropimorph resistance protein 2 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 3 papers)
TC 2.A.1.14.18 / P25621 Pantothenate:H+ symporter, Fen2 from Saccharomyces cerevisiae (Baker's yeast) (see 7 papers)
FEN2 / RF|NP_009957.1 pantothenate transporter FEN2 from Saccharomyces cerevisiae
25% identity, 72% coverage of query (74.3 bits)
GarP / b3127 galactarate/D-glucarate transporter GarP from Escherichia coli K-12 substr. MG1655 (see 6 papers)
garP / P0AA80 galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 5 papers)
GARP_ECOLI / P0AA80 Probable galactarate/D-glucarate transporter GarP from Escherichia coli (strain K12) (see 2 papers)
23% identity, 92% coverage of query (72.4 bits)
LgoT / b4356 galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
lgoT / P39398 galactonate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
LGOT_ECOLI / P39398 Probable L-galactonate transporter; Galactonate:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
yjjL / RF|NP_418776 inner membrane transport protein yjjL from Escherichia coli K12 (see 2 papers)
23% identity, 94% coverage of query (72.4 bits)
TC 2.A.1.14.14 / Q8FDB7 Probable D-galactarate (glucarate?):H+ symporter, GarP or YhaU from Escherichia coli O6 (see paper)
23% identity, 92% coverage of query (72.4 bits)
YidT / b3691 D-galactonate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 9 papers)
dgoT / P0AA76 D-galactonate:H+ symporter from Escherichia coli (strain K12) (see 11 papers)
DGOT_ECOLI / P0AA76 D-galactonate transporter; D-galactonate/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.14.7 / P0AA76 Galactonate transporter from Escherichia coli (see 4 papers)
24% identity, 94% coverage of query (72.4 bits)
6e9nA / J7QAK3 E. Coli d-galactonate:proton symporter in the inward open form (see paper)
22% identity, 91% coverage of query (71.2 bits)
S17A5_HUMAN / Q9NRA2 Sialin; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; AST; Membrane glycoprotein HP59; Solute carrier family 17 member 5; Vesicular excitatory amino acid transporter; VEAT from Homo sapiens (Human) (see 10 papers)
TC 2.A.1.14.10 / Q9NRA2 Lysosomal sialate transporter (Salla disease and infantile sialate storage disease protein (Morin et al., 2004)). Also transports glucuronic acid and aspartate. Structure-function studies have identify crucial residues and substrate-induced conformational changes (Courville et al., 2010). Also called SLC17A5. The substrate binding pocket has been identified based on modeling studies (see 8 papers)
23% identity, 82% coverage of query (63.5 bits)
6e9oA E. Coli d-galactonate:proton symporter mutant e133q in the outward substrate-bound form
25% identity, 91% coverage of query (62.4 bits)
S17A5_MOUSE / Q8BN82 Sialin; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; AST; Solute carrier family 17 member 5; Vesicular excitatory amino acid transporter; VEAT from Mus musculus (Mouse) (see 3 papers)
23% identity, 76% coverage of query (57.4 bits)
6zguA Crystal structure of a mfs transporter with bound 3-(2-methylphenyl) propanoic acid at 2.41 angstroem resolution
24% identity, 77% coverage of query (55.8 bits)
6zgtA Crystal structure of a mfs transporter with bound 2-naphthoic acid at 2.39 angstroem resolution
24% identity, 77% coverage of query (55.8 bits)
6zgsA / A0LNN5 Crystal structure of a mfs transporter with bound 3-phenylpropanoic acid at 2.39 angstroem resolution
24% identity, 77% coverage of query (55.8 bits)
6g9xA Crystal structure of a mfs transporter at 2.54 angstroem resolution
23% identity, 77% coverage of query (52.0 bits)
6zgrA Crystal structure of a mfs transporter with bound 1- hydroxynaphthalene-2-carboxylic acid at 2.67 angstroem resolution
22% identity, 85% coverage of query (50.8 bits)
SFMCT_SYNFM / A0LNN5 L-lactate transporter; SfMCT from Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) (see paper)
25% identity, 77% coverage of query (50.8 bits)
S17A5_RAT / Q5Q0U0 Sialin; H(+)/nitrate cotransporter; H(+)/sialic acid cotransporter; AST; Solute carrier family 17 (Anion/sugar transporter), member 5; Vesicular excitatory amino acid transporter; VEAT from Rattus norvegicus (Rat) (see 2 papers)
23% identity, 76% coverage of query (50.4 bits)
6zgrB Crystal structure of a mfs transporter with bound 1- hydroxynaphthalene-2-carboxylic acid at 2.67 angstroem resolution
22% identity, 85% coverage of query (48.5 bits)
6g9xB / A0LNN5 Crystal structure of a mfs transporter at 2.54 angstroem resolution (see paper)
22% identity, 85% coverage of query (48.5 bits)
PCAK_PSEPU / Q51955 4-hydroxybenzoate transporter PcaK from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
TC 2.A.1.15.1 / Q51955 4-Hydroxybenzoate/protocatechuate porter from Pseudomonas putida (see paper)
pcaK / AAA85137.1 PcaK from Pseudomonas putida (see paper)
22% identity, 83% coverage of query (47.0 bits)
6zguB Crystal structure of a mfs transporter with bound 3-(2-methylphenyl) propanoic acid at 2.41 angstroem resolution
23% identity, 77% coverage of query (46.2 bits)
6zgtB Crystal structure of a mfs transporter with bound 2-naphthoic acid at 2.39 angstroem resolution
23% identity, 77% coverage of query (46.2 bits)
6zgsB Crystal structure of a mfs transporter with bound 3-phenylpropanoic acid at 2.39 angstroem resolution
23% identity, 77% coverage of query (46.2 bits)
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Lawrence Berkeley National Laboratory