Sites on a Tree

 

Searching for up to 100 curated homologs for AO353_29315 FitnessBrowser__pseudo3_N2E3:AO353_29315 (304 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PotH / b0856 putrescine ABC transporter membrane subunit PotH (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
PotH / P31135 putrescine ABC transporter membrane subunit PotH (EC 7.6.2.11) from Escherichia coli (strain K12) (see paper)
POTH_ECOLI / P31135 Putrescine transport system permease protein PotH from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.11.2 / P31135 PotH aka B0856, component of Putrescine porter from Escherichia coli (see 5 papers)
potH putrescine transport system permease protein PotH from Escherichia coli K12 (see 5 papers)
    60% identity, 96% coverage of query (348 bits)

PotB / b1125 spermidine preferential ABC transporter membrane subunit PotB (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
PotB / P0AFK4 spermidine preferential ABC transporter membrane subunit PotB (EC 7.6.2.11) from Escherichia coli (strain K12) (see 2 papers)
TC 3.A.1.11.1 / P0AFK4 Spermidine/putrescine transport system permease protein PotB aka B1125, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 5 papers)
potB spermidine/putrescine ABC transporter, permease protein PotB from Escherichia coli K12 (see 5 papers)
    41% identity, 89% coverage of query (198 bits)

Q8YM94 ABC-type polyamine transporter (subunit 1/3) (EC 7.6.2.11) from Nostoc sp. PCC 7120 = FACHB-418 (see paper)
    44% identity, 70% coverage of query (166 bits)

TC 3.A.1.11.3 / Q44382 MotC, component of Mannopine porter from Agrobacterium tumefaciens (see paper)
    33% identity, 77% coverage of query (142 bits)

Build an alignment

Build an alignment for AO353_29315 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

TC 3.A.1.11.4 / O70110 ChtI aka ChtJ, component of Chrysopine porter (see paper)
    29% identity, 88% coverage of query (133 bits)

A0A0K2E5X6 ABC-type polyamine transporter (subunit 3/4) (EC 7.6.2.11) from Streptococcus suis (see paper)
    30% identity, 88% coverage of query (124 bits)

TC 3.A.1.11.7 / Q97Q43 Spermidine/putrescine ABC transporter, permease protein, component of The spermidine/putrescine uptake porter, PotABCD from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4)
    28% identity, 88% coverage of query (121 bits)

GGTC_SYNY3 / Q55472 Osmoprotective compounds uptake permease protein GgtC from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
TC 3.A.1.1.32 / Q55472 Membrane bound sugar transport protein, component of The glucosylglycerol uptake transporter (functions in osmoprotection and also transports sucrose and trehalose (Mikkat and Hagemann, 2000) (most similar to 3.A.1.1.8) from Synechocystis sp. (strain PCC 6803) (see paper)
    26% identity, 85% coverage of query (68.2 bits)

TC 3.A.1.1.25 / Q72H67 Maltose transport system permease protein malF aka TT_C1628, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    25% identity, 76% coverage of query (63.9 bits)

PHNU_SALTY / P96064 Putative 2-aminoethylphosphonate transport system permease protein PhnU from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
TC 3.A.1.11.5 / P96064 PhnU aka STM0427, component of 2-aminoethyl phosphonate porter from Salmonella typhimurium (see 2 papers)
    25% identity, 70% coverage of query (59.7 bits)

WTPB_ARCFU / O30143 Molybdate/tungstate transport system permease protein WtpB from Archaeoglobus fulgidus (strain ATCC 49558 / DSM 4304 / JCM 9628 / NBRC 100126 / VC-16) (see paper)
TC 3.A.1.6.8 / O30143 Molybdate/tungstate transport system permease protein WtpB, component of Molybdate/tungstate transport system, ModABC (WtpABC) (ModA binds to ModBC with high affinity (0.11%u03BCM) and dissociates slowly; the complex is destabilized by nucleotide and substrate binding from Archaeoglobus fulgidus (strain ATCC 49558 / VC-16 / DSM 4304 / JCM 9628 / NBRC 100126)
    24% identity, 78% coverage of query (55.5 bits)

TC 3.A.1.1.44 / Q9KZ07 Putative maltose permease, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    23% identity, 71% coverage of query (52.0 bits)

TC 3.A.1.1.39 / Q9WYR1 Alpha-1,4-digalacturonate porter (Nanavati et al., 2006). Regulated by pectin utilization regulon UxaR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    23% identity, 91% coverage of query (48.5 bits)

YdcV / b1443 putative ABC transporter membrane subunit YdcV from Escherichia coli K-12 substr. MG1655 (see 4 papers)
ydcV / P0AFR9 putative ABC transporter membrane subunit YdcV from Escherichia coli (strain K12) (see 4 papers)
YDCV_ECOLI / P0AFR9 Inner membrane ABC transporter permease protein YdcV from Escherichia coli (strain K12) (see 2 papers)
    23% identity, 87% coverage of query (48.5 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory