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Searching for up to 100 curated homologs for AO356_00055 FitnessBrowser__pseudo5_N2C3_1:AO356_00055 (433 a.a.)

Found high-coverage hits (≥70%) to 38 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO356_21495 gamma-glutamylputrescine oxidase (EC 1.4.3.-) from Pseudomonas fluorescens FW300-N2C3
    32% identity, 100% coverage of query (206 bits)

YcjA / b1301 γ-glutamylputrescine oxidase from Escherichia coli K-12 substr. MG1655 (see 6 papers)
puuB / P37906 γ-glutamylputrescine oxidase from Escherichia coli (strain K12) (see 4 papers)
PUUB_ECOLI / P37906 Gamma-glutamylputrescine oxidoreductase; Gamma-Glu-Put oxidase; Gamma-glutamylputrescine oxidase; EC 1.4.3.- from Escherichia coli (strain K12) (see paper)
puuB / BAD88709.1 gamma-glutamylputrescine oxidase from Escherichia coli K-12 (see paper)
    32% identity, 97% coverage of query (205 bits)

Pf6N2E2_80 gamma-glutamylputrescine oxidase (EC 1.4.3.-) from Pseudomonas fluorescens FW300-N2E2
    32% identity, 91% coverage of query (188 bits)

amaA / Q88CC4 pipecolate oxidase (EC 1.5.3.7) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
    30% identity, 88% coverage of query (152 bits)

Build an alignment

Build an alignment for AO356_00055 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

Q6RH53 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus pantotrophus (see paper)
    29% identity, 97% coverage of query (143 bits)

Q1XEP4 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus versutus (see paper)
    28% identity, 96% coverage of query (136 bits)

Q6RH61 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus denitrificans (see paper)
    29% identity, 96% coverage of query (129 bits)

Q6RH44 taurine dehydrogenase (EC 1.4.99.2) from Paracoccus pantotrophus (see paper)
    28% identity, 96% coverage of query (122 bits)

nmpC / A0A222FYP8 4-methylaminobutanoate oxidase (EC 1.5.3.21) from Alicycliphilus sp. (see paper)
    27% identity, 91% coverage of query (118 bits)

O59445 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus horikoshii (see paper)
    23% identity, 82% coverage of query (80.9 bits)

Q8U022 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus furiosus (see paper)
    21% identity, 82% coverage of query (79.7 bits)

Dmgdh / Q63342 dimethylglycine dehydrogenase, mitochondrial (EC 1.5.8.4) from Rattus norvegicus (see 9 papers)
M2GD_RAT / Q63342 Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; EC 1.5.8.4 from Rattus norvegicus (Rat) (see 3 papers)
Q63342 dimethylglycine dehydrogenase (EC 1.5.8.4) from Rattus norvegicus (see 3 papers)
    24% identity, 89% coverage of query (77.4 bits)

3if9A / O31616 Crystal structure of glycine oxidase g51s/a54r/h244a mutant in complex with inhibitor glycolate (see paper)
    24% identity, 87% coverage of query (76.6 bits)

thiO / O31616 glycine oxidase monomer (EC 1.4.3.19; EC 1.4.3.3) from Bacillus subtilis (strain 168) (see 3 papers)
GLYOX_BACSU / O31616 Glycine oxidase; GO; EC 1.4.3.19 from Bacillus subtilis (strain 168) (see 5 papers)
    22% identity, 83% coverage of query (75.1 bits)

Q9DBT9 dimethylglycine dehydrogenase (EC 1.5.8.4) from Mus musculus (see paper)
    23% identity, 89% coverage of query (75.1 bits)

1ng3A Complex of thio (glycine oxidase) with acetyl-glycine
    23% identity, 87% coverage of query (75.1 bits)

4pabB / Q63342 Crystal structure of the precursor form of rat dmgdh complexed with tetrahydrofolate (see paper)
    24% identity, 87% coverage of query (74.3 bits)

2gagB Heteroteterameric sarcosine: structure of a diflavin metaloenzyme at 1.85 a resolution
    27% identity, 80% coverage of query (73.2 bits)

Q5RKL4 dimethylglycine dehydrogenase (EC 1.5.8.4) from Rattus norvegicus (see paper)
    23% identity, 89% coverage of query (72.8 bits)

GLYOX_BACLI / S5FMM4 Glycine oxidase; GO; BliGO; EC 1.4.3.19 from Bacillus licheniformis (see paper)
S5FMM4 glycine oxidase (EC 1.4.3.19) from Bacillus licheniformis (see paper)
    23% identity, 84% coverage of query (71.6 bits)

DMGDH / Q9UI17 dimethylglycine dehydrogenase (EC 1.5.8.4) from Homo sapiens (see 6 papers)
M2GD_HUMAN / Q9UI17 Dimethylglycine dehydrogenase, mitochondrial; ME2GLYDH; EC 1.5.8.4 from Homo sapiens (Human) (see 2 papers)
Q9UI17 dimethylglycine dehydrogenase (EC 1.5.8.4) from Homo sapiens (see 2 papers)
    23% identity, 87% coverage of query (70.9 bits)

7cyxA / Q81HQ7 Crystal strcuture of glycine oxidase from bacillus cereus atcc 14579 (see paper)
    24% identity, 84% coverage of query (70.5 bits)

Q5JFG2 proline dehydrogenase (EC 1.5.5.2) from Thermococcus kodakarensis (see paper)
    24% identity, 84% coverage of query (69.7 bits)

1y56B / O59089 Crystal structure of l-proline dehydrogenase from p.Horikoshii (see paper)
    22% identity, 83% coverage of query (69.3 bits)

O59089 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus horikoshii (see paper)
    22% identity, 83% coverage of query (68.9 bits)

L7T8Y9 glycine oxidase (EC 1.4.3.19) from Bacillus cereus (see 2 papers)
    24% identity, 84% coverage of query (68.2 bits)

SARDH / Q9UL12 sarcosine dehydrogenase (EC 1.5.8.3) from Homo sapiens (see 5 papers)
SARDH_HUMAN / Q9UL12 Sarcosine dehydrogenase, mitochondrial; SarDH; BPR-2; EC 1.5.8.3 from Homo sapiens (Human) (see 2 papers)
    25% identity, 87% coverage of query (67.0 bits)

Q5JFG7 proline dehydrogenase (EC 1.5.5.2) from Thermococcus kodakarensis (see paper)
    24% identity, 83% coverage of query (65.9 bits)

Q8U1G2 proline dehydrogenase (EC 1.5.5.2) from Pyrococcus furiosus (see paper)
    23% identity, 83% coverage of query (65.9 bits)

SarDH / Q64380 sarcosine dehydrogenase (EC 1.5.8.3) from Rattus norvegicus (see 10 papers)
SARDH_RAT / Q64380 Sarcosine dehydrogenase, mitochondrial; SarDH; EC 1.5.8.3 from Rattus norvegicus (Rat) (see 2 papers)
    25% identity, 93% coverage of query (60.8 bits)

Q76M73 proline dehydrogenase (EC 1.5.5.2) from Thermococcus profundus (see 2 papers)
    22% identity, 84% coverage of query (60.1 bits)

TSOXB_ARTSP / Q9AGP3 Sarcosine oxidase subunit beta; Sarcosine oxidase subunit B; Sarcosine oxidase (5,10-methylenetetrahydrofolate-forming) subunit beta; Tetrameric sarcosine oxidase subunit beta; TSOX subunit beta; EC 1.5.3.24 from Arthrobacter sp.
    27% identity, 80% coverage of query (59.3 bits)

soxB / P40875 sarcosine oxidase β subunit (EC 1.5.3.24) from Corynebacterium sp. (strain P-1) (see 3 papers)
TSOXB_CORS1 / P40875 Sarcosine oxidase subunit beta; Sarcosine oxidase subunit B; Sarcosine oxidase (5,10-methylenetetrahydrofolate-forming) subunit beta; Tetrameric sarcosine oxidase subunit beta; TSOX subunit beta; EC 1.5.3.24 from Corynebacterium sp. (strain P-1) (see 7 papers)
    27% identity, 80% coverage of query (58.9 bits)

TSOXB_CORS9 / Q50LF2 Sarcosine oxidase subunit beta; Sarcosine oxidase subunit B; Sarcosine oxidase (5,10-methylenetetrahydrofolate-forming) subunit beta; Tetrameric sarcosine oxidase subunit beta; TSOX subunit beta; EC 1.5.3.24 from Corynebacterium sp. (strain U-96) (see 9 papers)
Q50LF2 sarcosine oxidase (subunit 3/4) (EC 1.5.3.1) from Corynebacterium sp. U-96 (see paper)
    26% identity, 80% coverage of query (55.1 bits)

1vrqB Crystal structure of heterotetrameric sarcosine oxidase from corynebacterium sp. U-96 in complex with folinic acid
    26% identity, 80% coverage of query (55.1 bits)

3ad7B / Q50LF2 Heterotetrameric sarcosine oxidase from corynebacterium sp. U-96 in complex with methylthio acetate (see paper)
    26% identity, 80% coverage of query (54.7 bits)

3ad8B Heterotetrameric sarcosine oxidase from corynebacterium sp. U-96 in complex with pyrrole 2-carboxylate
    26% identity, 80% coverage of query (54.7 bits)

mabO / Q8GAI3 4-methylaminobutyrate oxidase (demethylating) (EC 1.5.3.19) from Paenarthrobacter nicotinovorans (see 2 papers)
MABO1_PAENI / Q8GAI3 4-methylaminobutanoate oxidase (formaldehyde-forming); MABO; Demethylating gamma-N-methylaminobutyrate oxidase; Gamma-N-methylaminobutyrate oxidase 1; EC 1.5.3.19 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see 2 papers)
    26% identity, 83% coverage of query (53.5 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory