Searching for up to 100 curated homologs for AO356_00615 FitnessBrowser__pseudo5_N2C3_1:AO356_00615 (407 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO356_13805 ABC transporter for Carnitine, ATPase component from Pseudomonas fluorescens FW300-N2C3
    78% identity, 97% coverage of query (622 bits)

Pf6N2E2_4681 ABC transporter for Carnitine, ATPase component from Pseudomonas fluorescens FW300-N2E2
    78% identity, 97% coverage of query (619 bits)

AO353_07790 ABC transporter for Carnitine, ATPase component from Pseudomonas fluorescens FW300-N2E3
    76% identity, 97% coverage of query (608 bits)

TC 3.A.1.12.12 / Q9HTI8 Probable ATP-binding component of ABC transporter, component of The CbcWV/CbcX (choline)/CaiX (carnitine)/BetX (betaine) transporter with 3 binding receptors for distinct quaternary ammonium compounds. Only the ligand-bound receptor binds to the transporter with high affinity from Pseudomonas aeruginosa (see paper)
    69% identity, 97% coverage of query (561 bits)

TC 3.A.1.12.5 / Q9RQ06 BusAA, component of Uptake system for glycine-betaine (high affinity) and proline (low affinity) (OpuAA-OpuABC) or BusAA-ABC of Lactococcus lactis). BusAA, the ATPase subunit, has a C-terminal tandem cystathionine β-synthase (CBS) domain which is the cytoplasmic K+ sensor for osmotic stress (osmotic strength)while the BusABC subunit has the membrane and receptor domains fused to each other (Biemans-Oldehinkel et al., 2006; Mahmood et al., 2006; Gul et al. 2012). An N-terminal amphipathic α-helix of OpuA is necessary for high activity but is not critical for biogenesis or the ionic regulation of transport from Lactococcus lactis (see paper)
    44% identity, 94% coverage of query (300 bits)

OPUAA_BACSU / P46920 Glycine betaine transport ATP-binding protein OpuAA; Quaternary-amine-transporting ATPase; EC 7.6.2.9 from Bacillus subtilis (strain 168) (see 2 papers)
P46920 ABC-type quaternary amine transporter (EC 7.6.2.9) from Bacillus subtilis (see paper)
TC 3.A.1.12.2 / P46920 OPAA aka OpuAA, component of Glycine betaine OpuAA/AB/AC porter (also transports dimethylsulfonioacetate and dimethylsulfoniopropionate) from Bacillus subtilis (see 4 papers)
    43% identity, 95% coverage of query (299 bits)

7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
    44% identity, 94% coverage of query (295 bits)

7ahhC Opua inhibited inward-facing, sbd docked
    44% identity, 94% coverage of query (295 bits)

TC 3.A.1.12.9 / Q8U4S5 OtaA, component of The salt-induced glycine betaine OtaABC transporter from Methanosarcina mazei (see 2 papers)
    43% identity, 94% coverage of query (289 bits)

OUSV_DICD3 / E0SCY1 Glycine betaine/choline transport system ATP-binding protein OusV from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    42% identity, 92% coverage of query (278 bits)

GBUA_LISM4 / Q9RR46 Glycine betaine/carnitine transport ATP-binding protein GbuA; EC 7.6.2.9 from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
    39% identity, 97% coverage of query (273 bits)

TC 3.A.1.12.11 / Q8Q041 Glycine betaine transporter, ATP-binding protein, component of The glycine betaine uptake porter, GbpABCD from Methanosarcina mazei (see paper)
    40% identity, 74% coverage of query (203 bits)

OPUCA_LISM4 / G2JZ44 Carnitine transport ATP-binding protein OpuCA; EC 7.6.2.9 from Listeria monocytogenes serotype 1/2a (strain 10403S) (see 4 papers)
OPUCA_LISMN / Q9KHT9 Carnitine transport ATP-binding protein OpuCA; EC 7.6.2.9 from Listeria monocytogenes (see paper)
    35% identity, 83% coverage of query (195 bits)

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Build an alignment for AO356_00615 and 13 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

4fwiB / Q8RDH4 Crystal structure of the nucleotide-binding domain of a dipeptide abc transporter (see paper)
    29% identity, 70% coverage of query (103 bits)

DPPD_CALS4 / Q8RDH4 Dipeptide transport ATP-binding protein DppD; EC 7.4.2.9 from Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM 11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis) (see paper)
    29% identity, 70% coverage of query (103 bits)

ABCAC_MOUSE / E9Q876 Glucosylceramide transporter ABCA12; ATP-binding cassette sub-family A member 12; EC 7.6.2.1 from Mus musculus (Mouse) (see 9 papers)
    25% identity, 74% coverage of query (92.8 bits)

6msmA / P13569 Phosphorylated, atp-bound human cystic fibrosis transmembrane conductance regulator (cftr) (see paper)
    28% identity, 72% coverage of query (79.0 bits)

6o2pA Complex of ivacaftor with cystic fibrosis transmembrane conductance regulator (cftr)
    28% identity, 72% coverage of query (79.0 bits)

6o1vA Complex of human cystic fibrosis transmembrane conductance regulator (cftr) and glpg1837
    28% identity, 72% coverage of query (79.0 bits)

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