Sites on a Tree

 

Searching for up to 100 curated homologs for AO356_02885 FitnessBrowser__pseudo5_N2C3_1:AO356_02885 (268 a.a.)

Found high-coverage hits (≥70%) to 93 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

No hits had 30% identity

Change minimum %identity:

Additional hits (identity < 30%)

Q13KT2 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Paraburkholderia xenovorans (see 2 papers)
    28% identity, 99% coverage of query (103 bits)

2xuaH / Q13KT2 Crystal structure of the enol-lactonase from burkholderia xenovorans lb400 (see paper)
    28% identity, 99% coverage of query (102 bits)

pcaL / AAC38246.1 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase from Rhodococcus opacus (see paper)
    34% identity, 91% coverage of query (99.8 bits)

Q0SH24 3-oxoadipate enol-lactonase (EC 3.1.1.24); 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) from Rhodococcus jostii (see paper)
    35% identity, 91% coverage of query (99.0 bits)

pcaD / AAC37150.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 11 papers)
    25% identity, 94% coverage of query (86.3 bits)

bioH / BAB39459.1 BioH from Kurthia sp. 538-KA26 (see paper)
    26% identity, 99% coverage of query (82.8 bits)

4uheA Structural studies of a thermophilic esterase from thermogutta terrifontis (malate bound)
    29% identity, 96% coverage of query (82.8 bits)

4uhfA / A0A0M3KKY6 Structural studies of a thermophilic esterase from thermogutta terrifontis (l37a mutant with butyrate bound) (see paper)
    29% identity, 96% coverage of query (82.4 bits)

4uhdA Structural studies of a thermophilic esterase from thermogutta terrifontis (acetate bound)
    29% identity, 96% coverage of query (82.4 bits)

catD / AAC46435.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 8 papers)
    26% identity, 96% coverage of query (81.3 bits)

ESTE_PSEFL / P22862 Arylesterase; Aryl-ester hydrolase; Carboxylic acid perhydrolase; PFE; Putative bromoperoxidase; EC 3.1.1.2; EC 1.-.-.- from Pseudomonas fluorescens (see 8 papers)
GI|951089 arylesterase; EC 1.-.-.-; EC 3.1.1.2 from Pseudomonas fluorescens (see 3 papers)
AAB60168.1 esterase from Pseudomonas fluorescens (see 2 papers)
    29% identity, 99% coverage of query (77.4 bits)

3ia2A Pseudomonas fluorescens esterase complexed to the r-enantiomer of a sulfonate transition state analog
    29% identity, 99% coverage of query (77.4 bits)

AO353_17230 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas fluorescens FW300-N2E3
    27% identity, 97% coverage of query (75.1 bits)

8pi1B / P22862 Bicyclic incypro pseudomonas fluorescens esterase (see paper)
    29% identity, 99% coverage of query (74.7 bits)

pcaD / AAF34270.1 beta-ketoadipate enol-lactone hydrolase from Agrobacterium tumefaciens (see 2 papers)
    29% identity, 100% coverage of query (74.7 bits)

3hi4A Switching catalysis from hydrolysis to perhydrolysis in p. Fluorescens esterase
    29% identity, 99% coverage of query (74.3 bits)

3heaA The l29p/l124i mutation of pseudomonas fluorescens esterase
    29% identity, 99% coverage of query (74.3 bits)

pcaD / Q88N36 subunit of 3-oxoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 5 papers)
Q88N36 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Pseudomonas putida (see paper)
    29% identity, 92% coverage of query (72.8 bits)

4ccwA / Q59248 Crystal structure of naproxen esterase (carboxylesterase np) from bacillus subtilis (see paper)
    24% identity, 93% coverage of query (66.2 bits)

6i8wB / Q9KJG6 Crystal structure of a membrane phospholipase a, a novel bacterial virulence factor (see paper)
    26% identity, 94% coverage of query (65.9 bits)

Q9KJG6 triacylglycerol lipase (EC 3.1.1.3) from Pseudomonas aeruginosa (see paper)
    26% identity, 94% coverage of query (65.5 bits)

NAP_BACSU / P96688 Uncharacterized carboxylesterase nap; EC 3.1.1.1 from Bacillus subtilis (strain 168)
    24% identity, 93% coverage of query (65.5 bits)

D0EPY0 carboxylesterase (EC 3.1.1.1) from Bacillus subtilis (see paper)
    24% identity, 93% coverage of query (65.1 bits)

8agsAAA / A0A1U9WZ52 8agsAAA
    26% identity, 97% coverage of query (65.1 bits)

8agnAAA Alpha/beta epoxide hydrolase
    26% identity, 97% coverage of query (65.1 bits)

8agmAAA Alpha/beta epoxide hydrolase
    26% identity, 97% coverage of query (65.1 bits)

8agpAAA Alpha/beta epoxide hydrolase
    26% identity, 97% coverage of query (65.1 bits)

5ng7B Novel epoxide hydrolases belonging to the alpha/beta hydrolases superfamily in metagenomes from hot environments
    26% identity, 97% coverage of query (65.1 bits)

estRB8 / CAE54381.1 carboxylesterase, partial from Oleispira antarctica (see paper)
estRB8 / CAE54384.1 carboxylesterase from Oleispira antarctica (see paper)
    26% identity, 90% coverage of query (64.7 bits)

TGND_ACIAD / Q6F9F4 (E)-2-((N-methylformamido)methylene)succinate hydrolase; MFMS hydrolase; EC 3.5.1.- from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
    25% identity, 98% coverage of query (64.3 bits)

6i5gA X-ray structure of human soluble epoxide hydrolasE C-terminal domain (hseh ctd)in complex with 15d-pgj2
    26% identity, 84% coverage of query (63.9 bits)

4x6yA Human soluble epoxide hydrolase in complex with a cyclopropyl urea derivative
    26% identity, 84% coverage of query (63.9 bits)

4x6xA Human soluble epoxide hydrolase in complex with a three substituted cyclopropane derivative
    26% identity, 84% coverage of query (63.9 bits)

3antA Human soluble epoxide hydrolase in complex with a synthetic inhibitor
    26% identity, 84% coverage of query (63.9 bits)

3ansA Human soluble epoxide hydrolase in complex with a synthetic inhibitor
    26% identity, 84% coverage of query (63.9 bits)

7ebaA Co-crystal of kurarinone with seh
    26% identity, 84% coverage of query (63.9 bits)

4c4zA Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with a8
    26% identity, 84% coverage of query (63.9 bits)

4jncA Soluble epoxide hydrolase complexed with a carboxamide inhibitor
    26% identity, 84% coverage of query (63.5 bits)

4c4xA Crystal structure of human bifunctional epoxide hydroxylase 2 complexed with c9
    26% identity, 84% coverage of query (63.5 bits)

acoC / AAA21950.1 FMP from Cupriavidus necator (see paper)
    30% identity, 98% coverage of query (61.6 bits)

A4Q9R7 haloalkane dehalogenase (EC 3.8.1.5) from Mycobacterium tuberculosis variant bovis (see paper)
    25% identity, 95% coverage of query (61.2 bits)

O73957 carboxylesterase (EC 3.1.1.1) from Sulfolobus acidocaldarius (see paper)
    27% identity, 92% coverage of query (60.5 bits)

RutD / b1009 putative aminoacrylate hydrolase RutD from Escherichia coli K-12 substr. MG1655 (see 2 papers)
RUTD_ECOLI / P75895 Putative carbamate hydrolase RutD; Aminohydrolase; EC 3.5.1.- from Escherichia coli (strain K12) (see 5 papers)
    26% identity, 89% coverage of query (60.5 bits)

YBFK_BACSU / O31452 Carboxylesterase YbfK; EC 3.1.1.1 from Bacillus subtilis (strain 168) (see paper)
    24% identity, 93% coverage of query (59.3 bits)

thcF / AAC45285.1 chloroperoxidase from Rhodococcus erythropolis (see 2 papers)
    30% identity, 100% coverage of query (58.5 bits)

G3KFX4 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas sp. (see paper)
    28% identity, 90% coverage of query (56.2 bits)

EstN1 / K0IAM1 pimeloyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85) from Nitrososphaera gargensis (strain Ga9.2) (see paper)
    24% identity, 97% coverage of query (55.5 bits)

5cbkA / A0A0M5I297 Crystal structure of the strigolactone receptor shhtl5 from striga hermonthica (see paper)
    26% identity, 91% coverage of query (55.5 bits)

MhpC / b0349 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpC / P77044 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (strain K12) (see 10 papers)
MHPC_ECOLI / P77044 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase; 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; EC 3.7.1.14 from Escherichia coli (strain K12) (see 4 papers)
P77044 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (see 4 papers)
    27% identity, 96% coverage of query (54.7 bits)

2d0dA Crystal structure of a meta-cleavage product hydrolase (cumd) a129v mutant
    28% identity, 93% coverage of query (54.3 bits)

8dvcA Receptor shhtl5 from striga hermonthica in complex with strigolactone agonist gr24
    26% identity, 91% coverage of query (54.3 bits)

P96965 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas fluorescens (see 2 papers)
cumD / BAA12150.1 2-hydroxy-6-oxo-7-methylocta-2,4-dienoate hydrolase from Pseudomonas fluorescens (see paper)
    28% identity, 93% coverage of query (53.5 bits)

Q84II3 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Janthinobacterium sp. J3 (see paper)
    25% identity, 99% coverage of query (52.4 bits)

1iunB / P96965 Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant hexagonal (see paper)
    28% identity, 93% coverage of query (52.4 bits)

8hgwA / Q2MHH5 Crystal structure of mehph in complex with mbp (see paper)
    26% identity, 92% coverage of query (52.4 bits)

1ukaA Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with (s)-2-methylbutyrate
    28% identity, 93% coverage of query (52.4 bits)

1uk9A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with isovalerate
    28% identity, 93% coverage of query (52.4 bits)

1uk8A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-valerate
    28% identity, 93% coverage of query (52.4 bits)

1uk7A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-butyrate
    28% identity, 93% coverage of query (52.4 bits)

1iupA Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant complexed with isobutyrates
    28% identity, 93% coverage of query (52.4 bits)

carC / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)-hexa-2,4dienoate hydrolase monomer (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
CARC_PSERE / Q9AQM4 2-hydroxy-6-oxo-6-(2'-aminophenyl)hexa-2,4-dienoic acid hydrolase; HOPDA; EC 3.7.1.13 from Pseudomonas resinovorans (see 3 papers)
Q9AQM4 2-hydroxy-6-oxo-6-(2-aminophenyl)hexa-2,4-dienoate hydrolase (EC 3.7.1.13) from Pseudomonas resinovorans (see paper)
carC / BAC41548.1 meta cleavage compound hydrolase from Pseudomonas resinovorans (see 9 papers)
    25% identity, 99% coverage of query (51.6 bits)

5z7wB / A0A0M4AV81 Crystal structure of striga hermonthica htl1 (shhtl1) (see paper)
    24% identity, 94% coverage of query (51.6 bits)

Q9F1T8 hydroxybutyrate-dimer hydrolase (EC 3.1.1.22) from Acidovorax sp. SA1 (see paper)
    30% identity, 72% coverage of query (51.6 bits)

hbpD / O06648 2-hydroxy-6-oxo-6-phenyl-2,4-hexadienoate hydrolase [multifunctional] (EC 3.7.1.8) from Pseudomonas nitroreducens (see 2 papers)
    25% identity, 96% coverage of query (51.6 bits)

aamsh1 / Q988D4 2-(acetamidomethylene)succinate hydrolase monomer (EC 3.5.1.29) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (see 7 papers)
AAMHY_RHILO / Q988D4 2-(acetamidomethylene)succinate hydrolase; alpha-(N-acetylaminomethylene)succinic acid amidohydrolase; AAMS amidohydrolase; EC 3.5.1.29 from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099)) (see 2 papers)
Q988D4 2-(acetamidomethylene)succinate hydrolase (EC 3.5.1.29) from Mesorhizobium loti (see 2 papers)
    25% identity, 96% coverage of query (50.4 bits)

4gdmC / P37355 Crystal structure of e.Coli menh (see paper)
    26% identity, 83% coverage of query (50.1 bits)

4mysB 1.4 angstrom crystal structure of 2-succinyl-6-hydroxy-2,4- cyclohexadiene-1-carboxylate synthase with shchc and pyruvate
    26% identity, 83% coverage of query (50.1 bits)

4mydA 1.37 angstrom crystal structure of e. Coli 2-succinyl-6-hydroxy-2,4- cyclohexadiene-1-carboxylate synthase (menh) in complex with shchc
    26% identity, 83% coverage of query (50.1 bits)

YfbB / b2263 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.2.99.20) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
menH / P37355 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.2.99.20) from Escherichia coli (strain K12) (see 6 papers)
MENH_ECOLI / P37355 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; SHCHC synthase; EC 4.2.99.20 from Escherichia coli (strain K12) (see 2 papers)
P37355 palmitoyl-CoA hydrolase (EC 3.1.2.2); 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase (EC 4.2.99.20) from Escherichia coli (see 3 papers)
menH / RF|NP_416766 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase; EC 4.2.99.20 from Escherichia coli K12 (see 6 papers)
    26% identity, 83% coverage of query (50.1 bits)

4jymA / Q9SZU7 Crystal structure of kai2 in complex with 3-methyl-2h-furo[2,3- c]pyran-2-one (see paper)
    24% identity, 92% coverage of query (49.3 bits)

KAI2_ARATH / Q9SZU7 Probable esterase KAI2; Protein DWARF-14-like; Protein D14-like; Protein HYPOSENSITIVE TO LIGHT; Protein KARRIKIN INSENSITIVE 2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
    25% identity, 92% coverage of query (48.9 bits)

5z7xA / A0A0M4AMQ0 Crystal structure of striga hermonthica htl4 (shhtl4) (see paper)
    23% identity, 92% coverage of query (48.1 bits)

2edaA Crystallographic and fluorescence studies of the interaction of haloalkane dehalogenase with halide ions: studies with halide compounds reveal a halide binding site in the active site
    27% identity, 94% coverage of query (48.1 bits)

2dhcA Crystallographic analysis of the catalytic mechanism of haloalkane dehalogenase
    27% identity, 94% coverage of query (48.1 bits)

P22643 Haloalkane dehalogenase; EC 3.8.1.5 from Xanthobacter autotrophicus
    27% identity, 94% coverage of query (48.1 bits)

1cijA Haloalkane dehalogenase soaked with high concentration of bromide
    27% identity, 94% coverage of query (47.8 bits)

1be0A Haloalkane dehalogenase at ph 5.0 containing acetic acid
    27% identity, 94% coverage of query (47.8 bits)

1b6gA / P22643 Haloalkane dehalogenase at ph 5.0 containing chloride (see paper)
    27% identity, 94% coverage of query (47.8 bits)

5z7yA Crystal structure of striga hermonthica htl7 (shhtl7)
    23% identity, 92% coverage of query (47.8 bits)

7c8lA Hybrid designing of potent inhibitors of striga strigolactone receptor shhtl7
    23% identity, 92% coverage of query (47.8 bits)

7snuA / A0A0M3PNA2 Crystal structure of shhtl7 from striga hermonthica in complex with strigolactone antagonist rg6 (see paper)
    23% identity, 92% coverage of query (47.8 bits)

5dnuA / A0A0M3PN85 Crystal structure of striga kai2-like protein in complex with karrikin (see paper)
    26% identity, 97% coverage of query (47.4 bits)

7k38A Crystal structure of pisum sativum kai2 in complex with gr24-ent5ds product (see paper)
    22% identity, 92% coverage of query (46.2 bits)

5z89A Structural basis for specific inhibition of highly sensitive shhtl7 receptor
    23% identity, 92% coverage of query (45.8 bits)

5zhsA Crystal structure of osd14 in complex with covalently bound kk052
    24% identity, 92% coverage of query (43.1 bits)

5zhtA Crystal structure of osd14 in complex with covalently bound kk073
    24% identity, 92% coverage of query (43.1 bits)

5zhrA Crystal structure of osd14 in complex with covalently bound kk094
    24% identity, 92% coverage of query (43.1 bits)

5yz7A Crystal structure of osd14 in complex with d-ring-opened 7'-carba-4bd
    24% identity, 92% coverage of query (43.1 bits)

4ihaA Crystal structure of rice dwarf14 (d14) in complex with a gr24 hydrolysis intermediate
    24% identity, 92% coverage of query (43.1 bits)

6ap8A Crystal structure of rice d14 bound to 2-(2-methyl-3-nitroanilino) benzoic acid
    24% identity, 92% coverage of query (42.7 bits)

5dj5A Crystal structure of rice dwarf14 in complex with synthetic strigolactone gr24
    24% identity, 92% coverage of query (42.7 bits)

D14_ORYSJ / Q10QA5 Strigolactone esterase D14; Protein DWARF 14; Protein DWARF 88; Protein HIGH-TILLERING DWARF 2; EC 3.1.-.- from Oryza sativa subsp. japonica (Rice) (see 11 papers)
    24% identity, 92% coverage of query (42.7 bits)

6brtA / A0A0D9Z3K8 F-box protein cth with hydrolase (see paper)
    24% identity, 92% coverage of query (42.4 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory