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Searching for up to 100 curated homologs for AO356_03355 FitnessBrowser__pseudo5_N2C3_1:AO356_03355 (318 a.a.)

Found high-coverage hits (≥70%) to 55 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

wbpK / P72144 UDP-N-acetyl-α-D-fucosamine dehydrogenase from Pseudomonas aeruginosa (see 2 papers)
    47% identity, 97% coverage of query (280 bits)

wreQ / Q6TP29 UDP-N-acetyl-α-D-quinovosamine dehydrogenase (EC 1.1.1.426) from Rhizobium etli (see 2 papers)
Q6TP29 UDP-N-acetyl-alpha-D-quinovosamine dehydrogenase (EC 1.1.1.426) from Rhizobium etli (see paper)
    44% identity, 95% coverage of query (244 bits)

ORF35x7 / CAA69124.1 ORF35x7 from Vibrio cholerae (see paper)
    41% identity, 98% coverage of query (242 bits)

wbpV / Q9RHC9 UDP-N-acetyl-α-D-quinovosamine dehydrogenase (EC 1.1.1.426) from Pseudomonas aeruginosa (see paper)
    41% identity, 97% coverage of query (241 bits)

wbiG / GI|3135686 putative epimerase/dehydratase WbiG from Burkholderia pseudomallei (see paper)
    37% identity, 98% coverage of query (207 bits)

Build an alignment

Build an alignment for AO356_03355 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

cpsG polysaccharide capsule synthesis protein CpsG from Streptococcus iniae (see paper)
    29% identity, 91% coverage of query (102 bits)

gnu / Q8X7P7 N-acetyl-α-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase (EC 5.1.3.26) from Escherichia coli O157:H7 (see 2 papers)
GNU_ECO57 / Q8X7P7 N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol 4-epimerase; GlcNAc-P-P-Und 4-epimerase; EC 5.1.3.26 from Escherichia coli O157:H7 (see paper)
gne UDP-N-acetylglucosamine 4-epimerase; EC 5.1.3.7 from Escherichia coli O157:H7 (see paper)
    24% identity, 99% coverage of query (92.4 bits)

GALE_MYCS2 / A0R5C5 UDP-glucose 4-epimerase; UDP-galactose 4-epimerase; Uridine diphosphate galactose 4-epimerase; EC 5.1.3.2 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis) (see paper)
    27% identity, 95% coverage of query (73.9 bits)

6zldA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-glucuronic acid and NAD
    25% identity, 97% coverage of query (71.6 bits)

6zl6A Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp and NAD
    25% identity, 97% coverage of query (71.6 bits)

6zllA Crystal structure of udp-glucuronic acid 4-epimerase from bacillus cereus in complex with udp-galacturonic acid and NAD (see paper)
    25% identity, 97% coverage of query (71.2 bits)

6zljA Crystal structure of udp-glucuronic acid 4-epimerase y149f mutant from bacillus cereus in complex with udp-4-deoxy-4-fluoro-glucuronic acid and NAD
    25% identity, 97% coverage of query (70.1 bits)

3BHD_KLEAE / P0DX23 3-beta-hydroxysteroid dehydrogenase; 3beta-HSD; EC 1.1.1.51 from Klebsiella aerogenes (Enterobacter aerogenes) (see paper)
    23% identity, 96% coverage of query (65.5 bits)

hsdD / P9WQP7 3 β-hydroxysteroid dehydrogenase (EC 5.3.3.1; EC 1.1.1.145) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
3BHS_MYCTU / P9WQP7 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase; Cholesterol dehydrogenase; EC 1.1.1.145; EC 5.3.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WQP7 3beta-hydroxy-DELTA5-steroid dehydrogenase (EC 1.1.1.145) from Mycobacterium tuberculosis (see paper)
    25% identity, 98% coverage of query (65.1 bits)

3BHD_MYCNE / P0DX24 3-beta-hydroxysteroid dehydrogenase; 3beta-HSD; EC 1.1.1.51 from Mycolicibacterium neoaurum (Mycobacterium neoaurum) (see paper)
    24% identity, 97% coverage of query (62.8 bits)

tylA2 / Q54144 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces fradiae (see 2 papers)
    25% identity, 97% coverage of query (61.6 bits)

A7K9F4 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Acanthocystis turfacea chlorella virus 1 (see paper)
    27% identity, 77% coverage of query (61.2 bits)

Q9WYX9 UDP-glucose 4-epimerase (EC 5.1.3.2); UDP-N-acetylglucosamine 4-epimerase (EC 5.1.3.7) from Thermotoga maritima (see paper)
4zrnA / Q9WYX9 Crystal structure of udp-glucose 4-epimerase (tm0509) with udp-glucose from hyperthermophilic eubacterium thermotoga maritima (see paper)
    23% identity, 94% coverage of query (61.2 bits)

CERR_CAUVN / A0A0H3C8X7 Ceramide reductase; EC 1.-.-.- from Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus) (see 2 papers)
    28% identity, 91% coverage of query (60.5 bits)

6kv9A / A0A003 Moee5 in complex with udp-glucuronic acid and NAD (see paper)
    26% identity, 94% coverage of query (60.5 bits)

6kvcA Moee5 in complex with udp-glucose and NAD
    27% identity, 94% coverage of query (60.1 bits)

graE / AAA99939.1 dTDP-glucose dehydratase from Streptomyces violaceoruber (see paper)
    25% identity, 92% coverage of query (59.7 bits)

UGA4E_THEGP / F8C4X8 UDP-glucuronate 4-epimerase; UGA4E; TgUGAE; EC 5.1.3.6 from Thermodesulfobacterium geofontis (strain OPF15)
    22% identity, 95% coverage of query (59.3 bits)

RHM2 / Q9LPG6 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM2 (EC 4.2.1.76) from Arabidopsis thaliana (see 2 papers)
RHM2_ARATH / Q9LPG6 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM2; NDP-rhamnose synthase; Protein MUCILAGE-MODIFIED 4; Protein RHAMNOSE BIOSYNTHESIS 2; Rhamnose biosynthetic enzyme 2; AtRHM2; UDP-L-rhamnose synthase MUM4; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    25% identity, 78% coverage of query (58.9 bits)

OLED_STRMK / B2FI29 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Stenotrophomonas maltophilia (strain K279a) (see paper)
B2FI29 2-alkyl-3-oxoalkanoate reductase (EC 1.1.1.412) from Stenotrophomonas maltophilia (see 2 papers)
    28% identity, 78% coverage of query (58.5 bits)

oleD / Q8EG63 hentriaconta-3,6,9,12,19,22,25,28-octaene-16-one-15-oate reductase (EC 1.1.1.412) from Shewanella oneidensis (strain MR-1) (see paper)
OLED_SHEON / Q8EG63 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Shewanella oneidensis (strain MR-1) (see paper)
    24% identity, 96% coverage of query (58.2 bits)

mtmE / Q194R3 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Streptomyces argillaceus (see paper)
    24% identity, 96% coverage of query (57.4 bits)

jadT / Q939Q5 dTDP-glucose 4,6-dehydratase (EC 4.2.1.46) from Streptomyces venezuelae (strain ATCC 10712 / CBS 650.69 / DSM 40230 / JCM 4526 / NBRC 13096 / PD 04745) (see paper)
    24% identity, 78% coverage of query (57.0 bits)

C5XWV7 cinnamoyl-CoA reductase (EC 1.2.1.44) from Sorghum bicolor (see paper)
    25% identity, 71% coverage of query (57.0 bits)

oleD / Q8PDW5 2-alkyl-3-oxo-fatty acid reductase monomer (EC 1.1.1.412) from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 2 papers)
OLED_XANCP / Q8PDW5 2-alkyl-3-oxoalkanoate reductase; EC 1.1.1.412 from Xanthomonas campestris pv. campestris (strain ATCC 33913 / DSM 3586 / NCPPB 528 / LMG 568 / P 25) (see 2 papers)
    25% identity, 71% coverage of query (57.0 bits)

1r66A / Q9ZGH3 Crystal structure of desiv (dtdp-glucose 4,6-dehydratase) from streptomyces venezuelae with NAD and tyd bound (see paper)
    24% identity, 95% coverage of query (57.0 bits)

1r6dA Crystal structure of desiv double mutant (dtdp-glucose 4,6- dehydratase) from streptomyces venezuelae with NAD and dau bound
    24% identity, 95% coverage of query (57.0 bits)

RMLB_STRGR / P29782 dTDP-glucose 4,6-dehydratase; EC 4.2.1.46 from Streptomyces griseus (see paper)
    23% identity, 96% coverage of query (56.6 bits)

YbjS / b0868 putative epimerase YbjS from Escherichia coli K-12 substr. MG1655 (see paper)
    23% identity, 96% coverage of query (56.2 bits)

6bwlA / Q3ESA4 X-ray structure of pal from bacillus thuringiensis (see paper)
    23% identity, 95% coverage of query (56.2 bits)

rmd / AAK53475.1 putative NDP-hexose epimerase/oxydoreductase from Xanthomonas campestris pv. campestris (see 4 papers)
    27% identity, 93% coverage of query (55.8 bits)

D2IX45 cinnamoyl-CoA reductase (EC 1.2.1.44) from Panicum virgatum (see paper)
    24% identity, 71% coverage of query (55.5 bits)

desIV / Q9ZGH3 dTDP-glucose 4,6-dehydratase monomer (EC 4.2.1.46) from Streptomyces venezuelae (see paper)
    23% identity, 95% coverage of query (55.5 bits)

YKJ7_SCHPO / Q9UT59 Putative uncharacterized oxidoreductase C513.07; EC 1.1.1.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    26% identity, 86% coverage of query (55.1 bits)

A0A3G2K823 dihydroflavonol 4-reductase (EC 1.1.1.219) from Lotus japonicus (see paper)
    25% identity, 77% coverage of query (54.7 bits)

8femA / A0A8T0SQV2 Panicum vigratum dihydroflavonol 4-reductase complexed with NADP (see paper)
    27% identity, 72% coverage of query (54.3 bits)

GAL102 putative uncharacterized protein TGD99 from Candida albicans (see paper)
    22% identity, 94% coverage of query (54.3 bits)

8fenA Panicum vigratum dihydroflavonol 4-reductase complexed with NADP and dhq
    27% identity, 72% coverage of query (54.3 bits)

M4DRB9 dihydroflavonol 4-reductase (EC 1.1.1.219) from Brassica rapa subsp. pekinensis (see paper)
    25% identity, 72% coverage of query (53.5 bits)

A0A5C1IY10 dihydroflavonol 4-reductase (EC 1.1.1.219) from Muscari aucheri (see paper)
    25% identity, 75% coverage of query (53.1 bits)

Rff / b3788 dTDP-glucose 4,6-dehydratase 2 (EC 4.2.1.46) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
rffG / P27830 dTDP-glucose 4,6-dehydratase 2 (EC 4.2.1.46) from Escherichia coli (strain K12) (see 5 papers)
RMLB2_ECOLI / P27830 dTDP-glucose 4,6-dehydratase 2; EC 4.2.1.46 from Escherichia coli (strain K12) (see 3 papers)
    22% identity, 99% coverage of query (52.0 bits)

RHM1 / Q9SYM5 trifunctional UDP-glucose 4,6-dehydratase/UDP-4-dehydro-6-deoxy-D-glucose 3,5-epimerase/UDP-4-dehydro-L-rhamnose-reductase RHM1 (EC 4.2.1.76) from Arabidopsis thaliana (see 3 papers)
RHM1_ARATH / Q9SYM5 Trifunctional UDP-glucose 4,6-dehydratase/UDP-4-keto-6-deoxy-D-glucose 3,5-epimerase/UDP-4-keto-L-rhamnose-reductase RHM1; Protein REPRESSOR OF LRX1 1; Rhamnose biosynthetic enzyme 1; AtRHM1; EC 4.2.1.76; EC 1.1.1.-; EC 5.1.3.- from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
    25% identity, 78% coverage of query (51.6 bits)

DCVR_ORYSI / D5L1S4 Divinyl chlorophyllide a 8-vinyl-reductase, chloroplastic; EC 1.3.1.75 from Oryza sativa subsp. indica (Rice) (see 2 papers)
D5L1S4 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) (EC 1.3.1.75) from Oryza sativa (see paper)
Q10LH0 3,8-divinyl protochlorophyllide a 8-vinyl-reductase (NADPH) (EC 1.3.1.75) from Oryza sativa (see 2 papers)
    25% identity, 83% coverage of query (51.2 bits)

NSDHL_MOUSE / Q9R1J0 Sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating; EC 1.1.1.170 from Mus musculus (Mouse) (see 4 papers)
Q9R1J0 3beta-hydroxysteroid-4alpha-carboxylate 3-dehydrogenase (decarboxylating) (EC 1.1.1.170) from Mus musculus (see paper)
    22% identity, 98% coverage of query (50.4 bits)

2hunA / O58151 Crystal structure of hypothetical protein ph0414 from pyrococcus horikoshii ot3
    24% identity, 97% coverage of query (49.7 bits)

auaH / H1ZZB0 4-hydroxy-2-methyl-3-oxo-4-farnesyl-3,4-dihydroquinoline-1-oxide 3-reductase (EC 1.1.1.394) from Stigmatella aurantiaca (see 2 papers)
AUAH_STIAU / H1ZZB0 Aurachin B dehydrogenase; EC 1.1.1.394 from Stigmatella aurantiaca (see 2 papers)
H1ZZB0 aurachin B dehydrogenase (EC 1.1.1.394) from Stigmatella aurantiaca (see paper)
    24% identity, 82% coverage of query (49.3 bits)

1bxkB / P27830 Dtdp-glucose 4,6-dehydratase from e. Coli
    22% identity, 75% coverage of query (47.4 bits)

8vr2B / Q1QD53 Crystal structure of the pcryo_0617 oxidoreductase/decarboxylase from psychrobacter cryohalolentis k5 in the presence of NAD and udp
    25% identity, 79% coverage of query (44.3 bits)

8fipA / A0A1B6PND3 Hypothetical anthocyanidin reducatase from sorghum bicolor- NADP+ complex (see paper)
    24% identity, 91% coverage of query (43.1 bits)

8fioA Hypothetical anthocyanidin reductase from sorghum bicolor-NADP(h) and naringenin complex
    24% identity, 91% coverage of query (43.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory