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Searching for up to 100 curated homologs for AO356_05200 FitnessBrowser__pseudo5_N2C3_1:AO356_05200 (419 a.a.)

Found high-coverage hits (≥70%) to 21 curated proteins.

Removed hits that are identical to the query, leaving 20

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AO353_03400 D-mannose isomerase (EC 5.3.1.7) from Pseudomonas fluorescens FW300-N2E3
    82% identity, 99% coverage of query (687 bits)

Pf1N1B4_597 D-mannose isomerase (EC 5.3.1.7) from Pseudomonas fluorescens FW300-N1B4
    86% identity, 100% coverage of query (680 bits)

PS417_22150 D-mannose isomerase (EC 5.3.1.7) from Pseudomonas simiae WCS417
    74% identity, 96% coverage of query (583 bits)

MANI_PSEC1 / A0A0P9JFY5 D-mannose isomerase; PsMIaseA; EC 5.3.1.7 from Pseudomonas cannabina pv. alisalensis (strain ATCC BAA-566 / CFBP 6866 / ICMP 15200 / BS91) (see paper)
    68% identity, 99% coverage of query (546 bits)

SquS / b3880 sulfoquinovose isomerase (EC 5.3.1.31; EC 5.3.1.7) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yihS / P32140 sulfoquinovose isomerase (EC 5.3.1.31; EC 5.3.1.7) from Escherichia coli (strain K12) (see 6 papers)
SQUS_ECOLI / P32140 Sulfoquinovose isomerase; SQ isomerase; Sulfoquinovose-sulfofructose isomerase; SQ-SF isomerase; EC 5.3.1.31 from Escherichia coli (strain K12) (see 3 papers)
yihS / RF|NP_418316 uncharacterized sugar isomerase yihS from Escherichia coli K12 (see paper)
    46% identity, 96% coverage of query (370 bits)

SQUS_SALTY / Q8ZKT7 Sulfoquinovose isomerase; SQ isomerase; Sulfoquinovose-sulfofructose isomerase; SQ-SF isomerase; EC 5.3.1.31 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 2 papers)
    46% identity, 96% coverage of query (369 bits)

7ag4D / Q8ZKT7 Crystal structure of active site mutant of sq isomerase (yihs-h248a) from salmonella enterica in complex with sulfofructose (sf) (see paper)
    45% identity, 96% coverage of query (365 bits)

2zblA Functional annotation of salmonella enterica yihs-encoded protein
    45% identity, 96% coverage of query (365 bits)

MANI_THEFU / A0A077LPS9 D-mannose isomerase; EC 5.3.1.7 from Thermobifida fusca (Thermomonospora fusca)
    49% identity, 93% coverage of query (337 bits)

PGA1_c16670 D-mannose isomerase (EC 5.3.1.7) from Phaeobacter inhibens BS107
    39% identity, 97% coverage of query (234 bits)

MANI_MARM1 / F2JVT6 D-mannose isomerase; MI; EC 5.3.1.7 from Marinomonas mediterranea (strain ATCC 700492 / JCM 21426 / NBRC 103028 / MMB-1) (see paper)
    30% identity, 88% coverage of query (153 bits)

BPHYT_RS02050 D-mannose isomerase (EC 5.3.1.7) from Burkholderia phytofirmans PsJN
    33% identity, 77% coverage of query (149 bits)

Ac3H11_2078 D-mannose isomerase (EC 5.3.1.7) from Acidovorax sp. GW101-3H11
    32% identity, 70% coverage of query (131 bits)

Sama_0560 D-mannose isomerase (EC 5.3.1.7) from Shewanella amazonensis SB2B
    30% identity, 81% coverage of query (121 bits)

Build an alignment

Build an alignment for AO356_05200 and 14 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

E0RU15 cellobiose epimerase (EC 5.1.3.11) from Spirochaeta thermophila (see 2 papers)
    25% identity, 81% coverage of query (72.4 bits)

G0GBL0 cellobiose epimerase (EC 5.1.3.11) from Spirochaeta thermophila (see paper)
    24% identity, 76% coverage of query (65.1 bits)

C6VW66 cellobiose epimerase (EC 5.1.3.11) from Dyadobacter fermentans (see 2 papers)
    23% identity, 80% coverage of query (63.9 bits)

D0MF61 cellobiose epimerase (EC 5.1.3.11) from Rhodothermus marinus (see paper)
    25% identity, 88% coverage of query (52.4 bits)

A5FA14 cellobiose epimerase (EC 5.1.3.11) from Flavobacterium johnsoniae (see 2 papers)
    21% identity, 79% coverage of query (52.0 bits)

Dfer_5652 / C6VWU2 mannose 2-epimerase monomer (EC 5.1.3.44) from Dyadobacter fermentans (strain ATCC 700827 / DSM 18053 / CIP 107007 / KCTC 52180 / NS114) (see paper)
C6VWU2 mannose 2-epimerase (EC 5.1.3.44) from Runella slithyformis (see paper)
    21% identity, 89% coverage of query (48.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory