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Searching for up to 100 curated homologs for AO356_09620 FitnessBrowser__pseudo5_N2C3_1:AO356_09620 (322 a.a.)

Found high-coverage hits (≥70%) to 14 curated proteins.

Removed hits that are identical to the query, leaving 13

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TC 3.A.1.12.6 / Q9KKE3 HutX aka HISX, component of Uptake system for hisitidine, proline, proline-betaine and glycine-betaine from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
    48% identity, 99% coverage of query (336 bits)

Build an alignment

Build an alignment for AO356_09620 and 1 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

7yleA / A3SME7 Rndmpx in complex with dmsp (see paper)
    25% identity, 89% coverage of query (98.6 bits)

A0A077T7U5 ABC-type quaternary amine transporter (subunit 2/3) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
    27% identity, 97% coverage of query (68.6 bits)

TC 3.A.1.12.12 / Q9HTI6 Putative uncharacterized protein, component of The CbcWV/CbcX (choline)/CaiX (carnitine)/BetX (betaine) transporter with 3 binding receptors for distinct quaternary ammonium compounds. Only the ligand-bound receptor binds to the transporter with high affinity from Pseudomonas aeruginosa (see paper)
    24% identity, 93% coverage of query (64.7 bits)

A0A077T7R8 ABC-type quaternary amine transporter (subunit 1/2) (EC 7.6.2.9) from Vibrio anguillarum serotype O1 (see paper)
    23% identity, 96% coverage of query (58.9 bits)

TMOX_RUEPO / Q5LT66 Trimethylamine N-oxide-binding protein; TMAO-binding protein from Ruegeria pomeroyi (strain ATCC 700808 / DSM 15171 / DSS-3) (Silicibacter pomeroyi) (see 2 papers)
    22% identity, 97% coverage of query (54.7 bits)

AO356_13815 ABC transporter for Carnitine, periplasmic substrate-binding component 1 from Pseudomonas fluorescens FW300-N2C3
    23% identity, 97% coverage of query (52.8 bits)

OUSX_DICD3 / E0SCY3 Glycine betaine-binding periplasmic protein OusX from Dickeya dadantii (strain 3937) (Erwinia chrysanthemi (strain 3937)) (see paper)
    24% identity, 94% coverage of query (51.2 bits)

4xz6A / Q5LT66 Tmox in complex with tmao (see paper)
    21% identity, 88% coverage of query (51.2 bits)

TMOX_PELUB / Q4FL33 Trimethylamine N-oxide-binding protein; TMAO-binding protein from Pelagibacter ubique (strain HTCC1062) (see paper)
    22% identity, 95% coverage of query (46.6 bits)

TC 3.A.1.12.7 / Q8RPR1 ChoX, component of High affinity (3 μM) choline-specific uptake system from Rhizobium meliloti (Sinorhizobium meliloti) (see paper)
    22% identity, 96% coverage of query (46.2 bits)

2regA / Q92N37 Abc-transporter choline binding protein in complex with choline (see paper)
    22% identity, 89% coverage of query (45.8 bits)

2rinA Abc-transporter choline binding protein in complex with acetylcholine
    22% identity, 89% coverage of query (45.8 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory