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Searching for up to 100 curated homologs for AO356_11540 FitnessBrowser__pseudo5_N2C3_1:AO356_11540 (231 a.a.)

Found high-coverage hits (≥70%) to 89 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

GTT2 / Q12390 glutathione transferase 2 monomer (EC 2.5.1.18) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 13 papers)
GST2_YEAST / Q12390 Glutathione S-transferase 2; GST-II; EC 2.5.1.18 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
    73% identity, 89% coverage of query (329 bits)

3ergA / Q12390 Crystal structure of gtt2 from saccharomyces cerevisiae in complex with glutathione sulfnate (see paper)
    73% identity, 89% coverage of query (328 bits)

3ibhA Crystal structure of saccharomyces cerevisiae gtt2 in complex with glutathione
    73% identity, 89% coverage of query (328 bits)

Build an alignment

Build an alignment for AO356_11540 and 3 homologs with ≥ 30% identity

Select sequences

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Change minimum %identity:

Additional hits (identity < 30%)

GSTF1_ARATH / P42769 Glutathione S-transferase PM239X14; GST class-phi; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
    29% identity, 76% coverage of query (67.4 bits)

Pf6N2E2_5292 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2E2
    28% identity, 87% coverage of query (65.1 bits)

AO356_16835 Maleylacetoacetate isomerase (EC 5.2.1.2) from Pseudomonas fluorescens FW300-N2C3
    29% identity, 87% coverage of query (63.5 bits)

3touA / Q8XVV6 Crystal structure of glutathione transferase (target efi-501058) from ralstonia solanacearum gmi1000 with gsh bound
    27% identity, 88% coverage of query (62.0 bits)

5f06A / U5GTL0 Crystal structure of glutathione transferase f7 from populus trichocarpa (see paper)
    29% identity, 84% coverage of query (62.0 bits)

Q59721 4-chlorobenzoate dehalogenase (EC 3.8.1.6) from Burkholderia sp. (see paper)
bphK / CAA54033.1 glutathione S-transferase from Paraburkholderia xenovorans LB400 (see paper)
    29% identity, 89% coverage of query (61.6 bits)

GSTF_HYOMU / P46423 Glutathione S-transferase; 25 kDa auxin-binding protein; GST class-phi; EC 2.5.1.18 from Hyoscyamus muticus (Egyptian henbane) (see paper)
    30% identity, 73% coverage of query (61.2 bits)

4g9hA / Q8D0L3 Crystal structure of glutahtione s-transferase homolog from yersinia pestis, target efi-501894, with bound glutathione
    29% identity, 82% coverage of query (60.8 bits)

2gdrA / Q59721 Crystal structure of a bacterial glutathione transferase (see paper)
    28% identity, 89% coverage of query (60.8 bits)

2dsaA Ternary complex of bphk, a bacterial gst
    28% identity, 89% coverage of query (60.8 bits)

Q56AY1 glutathione transferase (EC 2.5.1.18) from Vitis vinifera (see paper)
    27% identity, 94% coverage of query (60.5 bits)

1pmtA / P15214 Glutathione transferase from proteus mirabilis (see paper)
    28% identity, 93% coverage of query (59.7 bits)

GST_PROMI / P15214 Glutathione S-transferase GST-6.0; GST B1-1; EC 2.5.1.18 from Proteus mirabilis (see paper)
    28% identity, 93% coverage of query (59.7 bits)

GSTF3_MAIZE / P04907 Glutathione S-transferase 3; GST class-phi member 3; GST-III; EC 2.5.1.18 from Zea mays (Maize) (see 2 papers)
    29% identity, 91% coverage of query (59.3 bits)

Q8RW02 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    29% identity, 87% coverage of query (58.9 bits)

4e8hB / O61996 Structural of bombyx mori glutathione transferase bmgstd1 complex with gtt
    25% identity, 75% coverage of query (58.5 bits)

Q8GTB9 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    28% identity, 89% coverage of query (58.5 bits)

Q9WVL0 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Mus musculus (Mouse)
    27% identity, 73% coverage of query (58.5 bits)

Q8RW03 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    29% identity, 87% coverage of query (58.2 bits)

2cz2A / Q9WVL0 Crystal structure of glutathione transferase zeta 1-1 (maleylacetoacetate isomerase) from mus musculus (form-1 crystal)
    27% identity, 73% coverage of query (58.2 bits)

MAAI_RAT / P57113 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Rattus norvegicus (Rat) (see paper)
    28% identity, 73% coverage of query (57.8 bits)

Q8RW04 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    28% identity, 87% coverage of query (57.4 bits)

4zb6D / A0A0R4I980 Crystal structure of glutathione transferase ure2p4 from phanerochaete chrysosporium in complex with oxidized glutathione. (see paper)
    27% identity, 92% coverage of query (57.4 bits)

7rhpA / A0A7M7GUY7 Crystal structure of honeybee (apis mellifera) glutathione s- transferase amgstd1 (see paper)
    28% identity, 71% coverage of query (56.6 bits)

GSTD7_DROME / Q9VG93 Glutathione S-transferase D7; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    28% identity, 73% coverage of query (56.2 bits)

1jlvA / Q7KIF2 Anopheles dirus species b glutathione s-transferases 1-3 (see paper)
    28% identity, 72% coverage of query (56.2 bits)

4i97A / R4S8C5 The crystal structure of glutathione s-transferase sniggstd1a from scaptomyza nigrita in complex with glutathione
    29% identity, 72% coverage of query (56.2 bits)

MAIA_ASPFU / Q4WHT7 Maleylacetoacetate isomerase maiA; EC 5.2.1.2 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 3 papers)
    26% identity, 77% coverage of query (55.8 bits)

GST27 / CAA56047.1 glutathione transferase from Zea mays (see paper)
    29% identity, 74% coverage of query (55.8 bits)

A4LAG9 glutathione transferase (EC 2.5.1.18) from Vitis vinifera (see paper)
    24% identity, 82% coverage of query (55.8 bits)

B2ZHM6 glutathione dehydrogenase (ascorbate) (EC 1.8.5.1) from Pinus bungeana (see paper)
    27% identity, 88% coverage of query (55.8 bits)

4mk3A / Q1LJ46 Crystal structure of a glutathione transferase family member from cupriavidus metallidurans ch34, target efi-507362, with bound glutathione sulfinic acid (gso2h)
    25% identity, 76% coverage of query (55.5 bits)

FZLA_CAUVN / A0A0H3CDY2 FtsZ-localized protein A; FtsZ-binding protein FzlA from Caulobacter vibrioides (strain NA1000 / CB15N) (Caulobacter crescentus) (see 3 papers)
    25% identity, 85% coverage of query (55.5 bits)

Q8GTC0 glutathione transferase (EC 2.5.1.18) from Triticum aestivum (see paper)
    29% identity, 74% coverage of query (55.1 bits)

gst3b / CAB38119.1 Glutathione transferase III(b) from Zea mays (see paper)
    30% identity, 72% coverage of query (55.1 bits)

Q3MUP2 glutathione transferase (EC 2.5.1.18) from Hordeum vulgare (see paper)
    28% identity, 87% coverage of query (54.3 bits)

6ezyB / O80852 Arabidopsis thaliana gstf9, gsh and gsoh bound (see paper)
    25% identity, 90% coverage of query (54.3 bits)

GSTF9_ARATH / O80852 Glutathione S-transferase F9; AtGSTF9; AtGSTF7; GST class-phi member 9; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
    25% identity, 90% coverage of query (54.3 bits)

6f01B Arabidopsis thaliana gstf9, gso3 and gsoh bound
    25% identity, 90% coverage of query (54.3 bits)

3zmkB / G0XSZ1 Anopheles funestus glutathione-s-transferase epsilon 2 (gste2) protein structure from different alelles: a single amino acid change confers high level of ddt resistance and cross resistance to permethrin in a major malaria vector in africa (see paper)
    30% identity, 71% coverage of query (53.9 bits)

3m3mA / Q4K8I0 Crystal structure of glutathione s-transferase from pseudomonas fluorescens [pf-5]
    25% identity, 73% coverage of query (53.5 bits)

GSTFA_ARATH / P42761 Glutathione S-transferase F10; AtGSTF10; AtGSTF4; GST class-phi member 10; Protein EARLY RESPONSE TO DEHYDRATION 13; EC 2.5.1.18 from Arabidopsis thaliana (Mouse-ear cress) (see 3 papers)
    27% identity, 88% coverage of query (53.1 bits)

GSTZ1 / O43708 maleylacetoacetate isomerase/glutathione transferase ζ monomer (EC 2.5.1.18; EC 5.2.1.2) from Homo sapiens (see 11 papers)
MAAI_HUMAN / O43708 Maleylacetoacetate isomerase; MAAI; GSTZ1-1; Glutathione S-transferase zeta 1; EC 5.2.1.2; EC 2.5.1.18 from Homo sapiens (Human) (see 3 papers)
O43708 glutathione transferase (EC 2.5.1.18); maleylacetoacetate isomerase (EC 5.2.1.2) from Homo sapiens (see 8 papers)
    25% identity, 73% coverage of query (53.1 bits)

P42860 glutathione transferase (EC 2.5.1.18) from Lucilia cuprina (see paper)
    27% identity, 72% coverage of query (53.1 bits)

gst3a / CAB38118.1 Glutathione transferase III(a) from Zea mays (see paper)
    29% identity, 72% coverage of query (53.1 bits)

GSTD4_DROME / Q9VG96 Glutathione S-transferase D4; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    23% identity, 90% coverage of query (52.4 bits)

1fw1A / O43708 Glutathione transferase zeta/maleylacetoacetate isomerase (see paper)
    25% identity, 73% coverage of query (52.0 bits)

4zbdA Crystal structure of the glutathione transferase ure2p6 from phanerochaete chrysosporium in complex with glutathione reduced by x- ray irradiation at 100k
    27% identity, 85% coverage of query (52.0 bits)

4zb8A / A0A0R4I981 Crystal structure of the glutathione transferase ure2p6 from phanerochaete chrysosporium in complex with oxidized glutathione. (see paper)
    27% identity, 85% coverage of query (51.6 bits)

4pxoA / C5ATQ9 Crystal structure of maleylacetoacetate isomerase from methylobacteriu extorquens am1 with bound malonate and gsh (target efi-507068)
    30% identity, 74% coverage of query (51.6 bits)

GSTD5_DROME / Q9VG95 Glutathione S-transferase D5; EC 2.5.1.18 from Drosophila melanogaster (Fruit fly) (see paper)
    23% identity, 90% coverage of query (51.2 bits)

4is0A Structural insights into omega-class glutathione transferases: a snapshot of enzyme reduction and identification of the non-catalytic ligandin site.
    26% identity, 92% coverage of query (50.8 bits)

3vlnA Human glutathione transferase o1-1 c32s mutant in complex with ascorbic acid
    26% identity, 92% coverage of query (50.8 bits)

GSTd1-5 / CAB03592.1 GSTD1-5 protein from Anopheles gambiae (see 2 papers)
    26% identity, 72% coverage of query (50.4 bits)

GST1C_ANOGA / Q93112 Glutathione S-transferase 1, isoform C; AgGst1-alpha; Aggst1-5; DDT-dehydrochlorinase; GST class-theta; EC 2.5.1.18; EC 4.5.1.1 from Anopheles gambiae (African malaria mosquito) (see paper)
    26% identity, 72% coverage of query (50.4 bits)

Gst / b1635 glutathione S-transferase GstA (EC 2.5.1.18) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
gstA / P0A9D2 glutathione S-transferase GstA (EC 2.5.1.18) from Escherichia coli (strain K12) (see 8 papers)
GSTA_ECOLI / P0A9D2 Glutathione S-transferase GstA; GST B1-1; EC 2.5.1.18 from Escherichia coli (strain K12) (see 6 papers)
GST / BAA07509.1 glutathione transferase from Escherichia coli (see paper)
    30% identity, 70% coverage of query (50.1 bits)

6mhcA / P78417 Glutathione s-transferase omega 1 bound to covalent inhibitor 37 (see paper)
    26% identity, 92% coverage of query (50.1 bits)

GSTO1 / P78417 glutathione transferase, Ω class subunit (EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2) from Homo sapiens (see 2 papers)
GSTO1_HUMAN / P78417 Glutathione S-transferase omega-1; GSTO-1; Glutathione S-transferase omega 1-1; GSTO 1-1; Glutathione-dependent dehydroascorbate reductase; Monomethylarsonic acid reductase; MMA(V) reductase; S-(Phenacyl)glutathione reductase; SPG-R; EC 2.5.1.18; EC 1.8.5.1; EC 1.20.4.2 from Homo sapiens (Human) (see 5 papers)
P78417 methylarsonate reductase (EC 1.20.4.2); glutathione dehydrogenase (ascorbate) (EC 1.8.5.1); glutathione transferase (EC 2.5.1.18) from Homo sapiens (see 7 papers)
    26% identity, 92% coverage of query (50.1 bits)

4gltA / Q1GZF4 Crystal structure of glutathione s-transferase mfla_2116 (target efi- 507160) from methylobacillus flagellatus kt with gsh bound
    28% identity, 76% coverage of query (50.1 bits)

4yqvA Glutathione s-transferase omega 1 bound to covalent inhibitor c4-10
    26% identity, 92% coverage of query (50.1 bits)

4yqmA Glutathione s-transferase omega 1 bound to covalent inhibitor c1-27
    26% identity, 92% coverage of query (50.1 bits)

1eemA Glutathione transferase from homo sapiens
    26% identity, 92% coverage of query (50.1 bits)

6pnnA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n-(2- methoxyethyl)-n-methylsulfamoyl)phenyl)acetamide
    26% identity, 92% coverage of query (50.1 bits)

6pnoA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3-(n- isopropylsulfamoyl)phenyl)acetamide
    26% identity, 92% coverage of query (50.1 bits)

6pnmA Human gsto1-1 complexed with 2-chloro-n-(4-chloro-3- (morpholinosulfonyl)phenyl)acetamide
    26% identity, 92% coverage of query (50.1 bits)

5v3qA Human gsto1-1 complexed with ml175
    26% identity, 92% coverage of query (50.1 bits)

5uehA Structure of gsto1 covalently conjugated to quinolinic acid fluorosulfate
    26% identity, 92% coverage of query (50.1 bits)

1a0fA Crystal structure of glutathione s-transferase from escherichia coli complexed with glutathionesulfonic acid
    30% identity, 70% coverage of query (50.1 bits)

6mhdA Glutathione s-transferase omega 1 bound to covalent inhibitor 44
    26% identity, 92% coverage of query (50.1 bits)

XYLK / AAC44159.1 glutathione S-transferase from Cycloclasticus oligotrophus (see paper)
    26% identity, 94% coverage of query (49.7 bits)

4kgiC Crystal structure of a glutathione transferase family member from shigella flexneri, target efi-507258, bound gsh, tev-his-tag linker in active site
    29% identity, 70% coverage of query (48.9 bits)

Q5K5T6 glutathione transferase subunit (EC 2.5.1.18) from Escherichia coli (see 8 papers)
    25% identity, 74% coverage of query (48.9 bits)

3pr8A / Q88RE7 Structure of glutathione s-transferase(pp0183) from pseudomonas putida in complex with gsh
    26% identity, 73% coverage of query (48.9 bits)

5f8bA / Q4WB03 Crystallographic structure of psoe with co (see paper)
    26% identity, 74% coverage of query (48.1 bits)

PSOE_ASPFU / Q4WB03 Glutathione S-transferase psoE; Pseurotin biosynthesis protein E; EC 2.5.1.- from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 4 papers)
    26% identity, 74% coverage of query (47.8 bits)

1byeA / P12653 Glutathione s-transferase i from mais in complex with atrazine glutathione conjugate (see paper)
    25% identity, 93% coverage of query (47.8 bits)

4qq7A / B4E6Q3 Crystal structure of putative stringent starvation protein a from burkholderia cenocepacia with bound glutathione
    26% identity, 74% coverage of query (47.4 bits)

4hojA / O33374 Crystal structure of glutathione transferase homolog from neisseria gonorrhoeae, target efi-501841, with bound glutathione
    27% identity, 74% coverage of query (47.0 bits)

1axdA Structure of glutathione s-transferase-i bound with the ligand lactoylglutathione
    25% identity, 91% coverage of query (47.0 bits)

3g7iB Crystal structure of a delta class gst (adgstd4-4) from anopheles dirus, with glutathione complexed in one subunit
    26% identity, 72% coverage of query (46.6 bits)

4nhwD Crystal structure of glutathione transferase smc00097 from sinorhizobium meliloti, target efi-507275, with one glutathione bound per one protein subunit
    30% identity, 74% coverage of query (46.6 bits)

5g5aA / Q9SHH7 Glutathione transferase u25 from arabidopsis thaliana in complex with glutathione disulfide
    25% identity, 87% coverage of query (46.2 bits)

3f63A / Q9GN60 Crystal structure of a delta class gst (adgstd4-4) from anopheles dirus, in complex with s-hexyl glutathione (see paper)
    27% identity, 72% coverage of query (45.4 bits)

4ri6A / A9PHH6 Crystal structure of poplar glutathione transferase f1 (see paper)
    25% identity, 87% coverage of query (44.7 bits)

1f2eA / O33705 Structure of sphingomonad, glutathione s-transferase complexed with glutathione
GST / AAC46031.1 glutathione S-transferase from Sphingomonas paucimobilis (see paper)
    29% identity, 82% coverage of query (43.9 bits)

7rkaA / A0A1P8PEY0 Crystal structure analysis of colorado potato beetle glutathione-s transferase ldgstu1 (see paper)
    26% identity, 74% coverage of query (43.9 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory