Searching for up to 100 curated homologs for AO356_16855 FitnessBrowser__pseudo5_N2C3_1:AO356_16855 (417 a.a.)
Found high-coverage hits (≥70%) to 35 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
THRC_METAC / Q8TQD4 Threonine synthase; TS; EC 4.2.3.1 from Methanosarcina acetivorans (strain ATCC 35395 / DSM 2834 / JCM 12185 / C2A) (see paper)
GB|AAM05023.1 threonine synthase; EC 4.2.3.1 from Methanosarcina acetivorans C2A (see paper)
33% identity, 97% coverage of query (211 bits)
6cgqA Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
34% identity, 82% coverage of query (167 bits)
6nmxA / A8HUA2 Threonine synthase from bacillus subtilis atcc 6633 with plp and appa (see paper)
34% identity, 82% coverage of query (165 bits)
6cgqB Threonine synthase from bacillus subtilis atcc 6633 with plp and plp- ala
34% identity, 82% coverage of query (165 bits)
thrC / CAA82669.1 threonine synthase from Bacillus sp. (see paper)
33% identity, 80% coverage of query (161 bits)
O66740 threonine synthase (EC 4.2.3.1) from Aquifex aeolicus (see paper)
33% identity, 83% coverage of query (160 bits)
2zsjA / O66740 Crystal structure of threonine synthase from aquifex aeolicus vf5
33% identity, 83% coverage of query (160 bits)
THRC_MYCTU / P9WG59 Threonine synthase; TS; EC 4.2.3.1 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WG59 threonine synthase (EC 4.2.3.1) from Mycobacterium tuberculosis (see 2 papers)
33% identity, 79% coverage of query (145 bits)
2d1fA / P9WG59 Structure of mycobacterium tuberculosis threonine synthase (see paper)
33% identity, 79% coverage of query (145 bits)
P83823 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see paper)
Q5SL02 threonine synthase (EC 4.2.3.1) from Thermus thermophilus (see 2 papers)
3aexA / Q5SL02 Catalytic intermediate analogue of threonine synthase from thermus thermophilus hb8 (see paper)
34% identity, 78% coverage of query (143 bits)
1uimA Crystal structure of threonine synthase from thermus thermophilus hb8, orthorhombic crystal form
34% identity, 78% coverage of query (143 bits)
1v7cA Crystal structure of threonine synthase from thermus thermophilus hb8 in complex with a substrate analogue
34% identity, 78% coverage of query (143 bits)
3aeyA Apo form of threonine synthase from thermus thermophilus hb8
34% identity, 78% coverage of query (143 bits)
A0R220 Threonine synthase; TS; EC 4.2.3.1 from Mycolicibacterium smegmatis (strain ATCC 700084 / mc(2)155) (Mycobacterium smegmatis)
33% identity, 81% coverage of query (142 bits)
Build an alignment for AO356_16855 and 14 homologs with ≥ 30% identity
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THRC2_ARATH / Q9SSP5 Threonine synthase 2, chloroplastic; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
28% identity, 87% coverage of query (117 bits)
THRC1_ARATH / Q9S7B5 Threonine synthase 1, chloroplastic; Protein METHIONINE OVER-ACCUMULATOR 2; EC 4.2.3.1 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
27% identity, 95% coverage of query (114 bits)
2c2bA Crystallographic structure of arabidopsis thaliana threonine synthase complexed with pyridoxal phosphate and s-adenosylmethionine
27% identity, 95% coverage of query (114 bits)
DvMF_1945 threonine synthase (EC 4.2.3.1) from Desulfovibrio vulgaris Miyazaki F
30% identity, 77% coverage of query (109 bits)
2c2gA / Q9S7B5 Crystal structure of threonine synthase from arabidopsis thaliana in complex with its cofactor pyridoxal phosphate (see paper)
28% identity, 76% coverage of query (102 bits)
ILV / CAA10977.1 threonine deaminase from Blastobotrys adeninivorans (see paper)
27% identity, 71% coverage of query (85.1 bits)
ILV1 putative uncharacterized protein ILV1 from Candida albicans (see paper)
24% identity, 70% coverage of query (80.5 bits)
B1N2N4 L-serine ammonia-lyase (EC 4.3.1.17) from Entamoeba histolytica (see paper)
27% identity, 71% coverage of query (70.5 bits)
1tdjA / P04968 Threonine deaminase (biosynthetic) from e. Coli (see paper)
27% identity, 72% coverage of query (68.9 bits)
Ile / b3772 threonine deaminase (EC 4.3.1.19) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
ilvA / P04968 threonine deaminase (EC 4.3.1.19) from Escherichia coli (strain K12) (see 21 papers)
ILVA_ECOLI / P04968 L-threonine dehydratase biosynthetic IlvA; Threonine deaminase; EC 4.3.1.19 from Escherichia coli (strain K12) (see 4 papers)
P04968 threonine ammonia-lyase (EC 4.3.1.19) from Escherichia coli (see paper)
27% identity, 72% coverage of query (68.9 bits)
THDH_YEAST / P00927 Threonine dehydratase, mitochondrial; Threonine deaminase; EC 4.3.1.19 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 5 papers)
26% identity, 78% coverage of query (65.9 bits)
CysM / b2421 cysteine synthase B (EC 2.5.1.47; EC 2.5.1.144; EC 4.4.1.1; EC 4.4.1.28) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
cysM / P16703 cysteine synthase B (EC 2.5.1.47; EC 2.5.1.144; EC 4.4.1.1) from Escherichia coli (strain K12) (see 15 papers)
CYSM_ECOLI / P16703 Cysteine synthase B; CSase B; O-acetylserine (thiol)-lyase B; OAS-TL B; O-acetylserine sulfhydrylase B; EC 2.5.1.47 from Escherichia coli (strain K12) (see paper)
26% identity, 74% coverage of query (64.7 bits)
2bhtA / P16703 Crystal structure of o-acetylserine sulfhydrylase b (see paper)
25% identity, 74% coverage of query (62.8 bits)
4pcuA Crystal structure of delta516-525 e201s human cystathionine beta- synthase with adomet
24% identity, 78% coverage of query (54.7 bits)
7qgtB Crystal structure of human cystathionine beta-synthase (delta516-525) in complex with aoaa.
24% identity, 78% coverage of query (51.6 bits)
7qgtA / P35520 Crystal structure of human cystathionine beta-synthase (delta516-525) in complex with aoaa. (see paper)
24% identity, 78% coverage of query (51.6 bits)
CBS / P35520 cystathionine β-synthase monomer (EC 4.2.1.22) from Homo sapiens (see 12 papers)
CBS_HUMAN / P35520 Cystathionine beta-synthase; Beta-thionase; Serine sulfhydrase; EC 4.2.1.22 from Homo sapiens (Human) (see 43 papers)
P35520 cystathionine beta-synthase (EC 4.2.1.22) from Homo sapiens (see 18 papers)
24% identity, 78% coverage of query (51.2 bits)
3x43A Crystal structure of o-ureido-l-serine synthase
25% identity, 75% coverage of query (50.8 bits)
dcsD / D2Z027 O-ureido-L-serine synthase (EC 2.5.1.47; EC 2.6.99.3) from Streptomyces lavendulae (see 2 papers)
DCSD_STRLA / D2Z027 O-ureido-L-serine synthase; Cysteine synthase homolog DscD; O-acetylserine sulfhydrylase; EC 2.6.99.3; EC 2.5.1.47 from Streptomyces lavendulae (see 3 papers)
D2Z027 cysteine synthase (EC 2.5.1.47); O-ureido-L-serine synthase (EC 2.6.99.3) from Streptomyces lavendulae (see 4 papers)
25% identity, 75% coverage of query (50.8 bits)
3x44A / D2Z027 Crystal structure of o-ureido-l-serine-bound k43a mutant of o-ureido- l-serine synthase (see paper)
24% identity, 75% coverage of query (48.5 bits)
P0A879 Tryptophan synthase beta chain; EC 4.2.1.20 from Escherichia coli (strain K12)
25% identity, 72% coverage of query (46.6 bits)
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Lawrence Berkeley National Laboratory