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Searching for up to 100 curated homologs for AO356_21845 FitnessBrowser__pseudo5_N2C3_1:AO356_21845 (249 a.a.)

Found high-coverage hits (≥70%) to 23 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ETFB_ARATH / Q9LSW8 Electron transfer flavoprotein subunit beta, mitochondrial; Beta-ETF from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    54% identity, 100% coverage of query (265 bits)

1efpB / P38975 Electron transfer flavoprotein (etf) from paracoccus denitrificans (see paper)
    59% identity, 97% coverage of query (258 bits)

ETFB_MOUSE / Q9DCW4 Electron transfer flavoprotein subunit beta; Beta-ETF from Mus musculus (Mouse) (see paper)
    52% identity, 100% coverage of query (242 bits)

ETFB_BOVIN / Q2TBV3 Electron transfer flavoprotein subunit beta; Beta-ETF from Bos taurus (Bovine) (see paper)
    51% identity, 100% coverage of query (241 bits)

ETFB_RAT / Q68FU3 Electron transfer flavoprotein subunit beta; Beta-ETF from Rattus norvegicus (Rat) (see paper)
    52% identity, 100% coverage of query (240 bits)

ETFB_HUMAN / P38117 Electron transfer flavoprotein subunit beta; Beta-ETF from Homo sapiens (Human) (see 9 papers)
    51% identity, 100% coverage of query (240 bits)

ETFB_PIG / Q6UAQ8 Electron transfer flavoprotein subunit beta; Beta-ETF from Sus scrofa (Pig) (see paper)
    51% identity, 100% coverage of query (239 bits)

2a1uB / P38117 Crystal structure of the human etf e165betaa mutant (see paper)
    51% identity, 100% coverage of query (238 bits)

ETFB_YEAST / P42940 Probable electron transfer flavoprotein subunit beta; Beta-ETF; Changed intracellular redox state protein 1 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
    42% identity, 100% coverage of query (193 bits)

ETFB_SYNWW / Q0AZ34 Electron transfer flavoprotein subunit beta from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) (see 2 papers)
    40% identity, 77% coverage of query (138 bits)

CARD_ACEWD / H6LGM7 Caffeyl-CoA reductase-Etf complex subunit CarD; Electron transfer flavoprotein small subunit; ETFSS; Electron transfer flavoprotein subunit beta; Beta-ETF; EC 1.3.1.108 from Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) (see paper)
H6LGM7 caffeoyl-CoA reductase (subunit 2/3) (EC 1.3.1.108) from Acetobacterium woodii (see paper)
6fahB / H6LGM7 Molecular basis of the flavin-based electron-bifurcating caffeyl-coa reductase reaction (see paper)
    33% identity, 84% coverage of query (107 bits)

ETFB_METME / P53570 Electron transfer flavoprotein subunit beta; Beta-ETF; Electron transfer flavoprotein small subunit; ETFSS from Methylophilus methylotrophus (Bacterium W3A1) (see 2 papers)
AAA64952.1 electron transfer flavoprotein small subunit from Methylophilus methylotrophus W3A1 (see paper)
    33% identity, 97% coverage of query (100 bits)

1o96A / P53570 Structure of electron transferring flavoprotein for methylophilus methylotrophus. (see paper)
    34% identity, 97% coverage of query (100 bits)

7koeA / Q9X1L6 Electron bifurcating flavoprotein fix/etfabcx (see paper)
    32% identity, 91% coverage of query (94.7 bits)

D2RIQ2 butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin) (subunit 3/3) (EC 1.3.1.109) from Acidaminococcus fermentans (see paper)
4kpuB / D2RIQ2 Electron transferring flavoprotein of acidaminococcus fermentans: towards a mechanism of flavin-based electron bifurcation (see paper)
    33% identity, 83% coverage of query (94.0 bits)

4l2iB Electron transferring flavoprotein of acidaminococcus fermentans: towards a mechanism of flavin-based electron bifurcation
    33% identity, 83% coverage of query (94.0 bits)

Build an alignment

Build an alignment for AO356_21845 and 16 homologs with ≥ 30% identity

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Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

acrB / G3KIM7 electron-transferring flavoprotein β subunit from Anaerotignum propionicum (see paper)
ETFB_ANAPI / G3KIM7 Acryloyl-CoA reductase electron transfer subunit gamma; Electron transfer flavoprotein small subunit; ETFSS; Electron transfer flavoprotein subunit gamma; Gamma-ETF from Anaerotignum propionicum (Clostridium propionicum) (see paper)
    28% identity, 97% coverage of query (93.2 bits)

Q18AQ6 butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin) (subunit 2/3) (EC 1.3.1.109) from Clostridioides difficile (see paper)
5ol2B / A0A125V3V6 The electron transferring flavoprotein/butyryl-coa dehydrogenase complex from clostridium difficile (see paper)
    29% identity, 78% coverage of query (83.2 bits)

ETFB_MYCBO / P64098 Electron transfer flavoprotein subunit beta; Beta-ETF; Electron transfer flavoprotein small subunit; ETFSS from Mycobacterium bovis (strain ATCC BAA-935 / AF2122/97) (see paper)
    28% identity, 78% coverage of query (82.8 bits)

YdiQ / b1697 putative electron transfer flavoprotein subunit YdiQ from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    30% identity, 76% coverage of query (62.4 bits)

LCTB_ACEWD / H6LBB0 Lactate dehydrogenase (NAD(+),ferredoxin) subunit LctB; Electron transfer flavoprotein small subunit; Electron transfer flavoprotein subunit beta; EtfB; Lactate dehydrogenase-Etf complex subunit LctB; EC 1.1.1.436 from Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) (see paper)
H6LBB0 lactate dehydrogenase (NAD+, ferredoxin) (subunit 3/3) (EC 1.3.1.110) from Acetobacterium woodii (see paper)
    25% identity, 80% coverage of query (62.4 bits)

7qh2B / H6LBB0 Cryo-em structure of ldh-etfab complex from acetobacterium woodii (see paper)
    24% identity, 79% coverage of query (60.1 bits)

YaaQ / b0041 putative electron transfer flavoprotein FixA from Escherichia coli K-12 substr. MG1655 (see 6 papers)
FIXA_ECOLI / P60566 Protein FixA from Escherichia coli (strain K12) (see paper)
    25% identity, 84% coverage of query (50.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory