Searching for up to 100 curated homologs for AO356_27160 FitnessBrowser__pseudo5_N2C3_1:AO356_27160 (297 a.a.)
Found high-coverage hits (≥70%) to 82 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
Q7D0E8 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
46% identity, 99% coverage of query (214 bits)
3na8A / Q9I6R5 Crystal structure of a putative dihydrodipicolinate synthetase from pseudomonas aeruginosa
31% identity, 98% coverage of query (106 bits)
Build an alignment for AO356_27160 and 2 homologs with ≥ 30% identity
Or download the sequences
4dxvA / D0CFC3 Crystal structure of dihydrodipicolinate synthase from acinetobacter baumannii complexed with mg and cl ions at 1.80 a resolution
28% identity, 79% coverage of query (88.2 bits)
3u8gA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with oxalic acid at 1.80 a resolution
28% identity, 79% coverage of query (88.2 bits)
3tdfA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 2-ketobutanoic acid at 1.99 a resolution
28% identity, 79% coverage of query (88.2 bits)
3tceA Crystal structure of the complex of dihydrodipicolinate synthase from acinetobacter baumannii with 5-hydroxylysine at 2.6 a resolution
28% identity, 79% coverage of query (88.2 bits)
3rk8A Crystal structure of the chloride inhibited dihydrodipicolinate synthase from acinetobacter baumannii complexed with pyruvate at 1.8 a resolution
28% identity, 79% coverage of query (88.2 bits)
3pueB Crystal structure of the complex of dhydrodipicolinate synthase from acinetobacter baumannii with lysine at 2.6a resolution
28% identity, 79% coverage of query (88.2 bits)
DAPA_RHIML / Q07607 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; Protein MosA; EC 4.3.3.7 from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see 2 papers)
Q07607 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Sinorhizobium meliloti (see 2 papers)
27% identity, 97% coverage of query (87.0 bits)
4i7wA / F0L8Z6 Agrobacterium tumefaciens dhdps with lysine and pyruvate
31% identity, 85% coverage of query (86.3 bits)
DAPA_AGRFC / Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Agrobacterium fabrum (strain C58 / ATCC 33970) (Agrobacterium tumefaciens (strain C58)) (see paper)
Q8UGL3 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see 2 papers)
30% identity, 85% coverage of query (85.1 bits)
7kg2A Dihydrodipicolinate synthase (dhdps) from c.Jejuni, h59k mutant with pyruvate bound in the active site and l-histidine bound at the allosteric site
27% identity, 97% coverage of query (84.7 bits)
7kkdB / Q9PPB4 Dihydrodipicolinate synthase (dhdps) from c.Jejuni, n84a mutant with pyruvate bound in the active site and r,r-bislysine bound at the allosteric site
27% identity, 97% coverage of query (84.3 bits)
DAPA_NEIMB / Q9JZR4 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Neisseria meningitidis serogroup B (strain MC58) (see paper)
Q9JZR4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Neisseria meningitidis (see paper)
28% identity, 96% coverage of query (84.0 bits)
4m19A Dihydrodipicolinate synthase from c. Jejuni with pyruvate bound to the active site and lysine bound to allosteric site
27% identity, 97% coverage of query (83.6 bits)
6u01B Dihydrodipicolinate synthase (dhdps) from c.Jejuni, n84d mutant with pyruvate bound in the active site
27% identity, 97% coverage of query (83.2 bits)
4pfmA / A9DKW4 Shewanella benthica dhdps with lysine and pyruvate
27% identity, 95% coverage of query (82.4 bits)
dapA / Q65JG7 dihydrodipicolinate synthase subunit (EC 4.3.3.7) from Bacillus licheniformis (strain ATCC 14580 / DSM 13 / JCM 2505 / CCUG 7422 / NBRC 12200 / NCIMB 9375 / NCTC 10341 / NRRL NRS-1264 / Gibson 46) (see paper)
25% identity, 99% coverage of query (80.1 bits)
5t25A / B7M7I1 Kinetic, spectral and structural characterization of the slow binding inhibitor acetopyruvate with dihydrodipicolinate synthase from escherichia coli.
25% identity, 98% coverage of query (79.7 bits)
DAPA_THEMA / Q9X1K9 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
27% identity, 84% coverage of query (79.7 bits)
1o5kA / Q9X1K9 Crystal structure of dihydrodipicolinate synthase (tm1521) from thermotoga maritima at 1.80 a resolution
27% identity, 84% coverage of query (79.7 bits)
DapA / b2478 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli K-12 substr. MG1655 (see 24 papers)
dapA / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (strain K12) (see 23 papers)
DAPA_ECOLI / P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Escherichia coli (strain K12) (see 11 papers)
P0A6L2 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Escherichia coli (see 15 papers)
25% identity, 98% coverage of query (79.7 bits)
2atsA Dihydrodipicolinate synthase co-crystallised with (s)-lysine
25% identity, 98% coverage of query (79.7 bits)
3i7sA Dihydrodipicolinate synthase mutant - k161a - with the substrate pyruvate bound in the active site.
25% identity, 98% coverage of query (79.3 bits)
7lvlA / A0A0F4VK59 Dihydrodipicolinate synthase bound with allosteric inhibitor (s)- lysine from candidatus liberibacter solanacearum
29% identity, 80% coverage of query (78.6 bits)
7mjfA Crystal structure of candidatus liberibacter solanacearum dihydrodipicolinate synthase with pyruvate and succinic semi-aldehyde bound in active site
29% identity, 80% coverage of query (78.6 bits)
dapA / Q04796 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacillus subtilis (strain 168) (see paper)
26% identity, 99% coverage of query (78.2 bits)
O67216 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Aquifex aeolicus (see paper)
26% identity, 100% coverage of query (77.8 bits)
Q8RBI5 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Caldanaerobacter subterraneus subsp. tengcongensis (see paper)
25% identity, 98% coverage of query (76.6 bits)
dhdps / CAC50571.1 dihydrodipicolinate synthetase from Yersinia enterocolitica (see paper)
26% identity, 82% coverage of query (75.9 bits)
A9CFV4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
24% identity, 99% coverage of query (73.2 bits)
DAPAL_RHIML / O69782 Uncharacterized DapA-like lyase; EC 4.-.-.- from Rhizobium meliloti (Ensifer meliloti) (Sinorhizobium meliloti) (see paper)
27% identity, 87% coverage of query (72.8 bits)
Q6G468 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bartonella henselae (see paper)
28% identity, 82% coverage of query (69.7 bits)
dapA / P19808 dihydropicolinate synthase subunit (EC 4.3.3.7) from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
P19808 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Corynebacterium glutamicum (see paper)
dapA / CAA79714.1 dihydrodipicolinate synthase from Corynebacterium glutamicum (see paper)
28% identity, 82% coverage of query (68.2 bits)
YjhH / b4298 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
yjhH / P39359 KpLE2 phage-like element; putative 2-dehydro-3-deoxy-D-pentonate aldolase (EC 4.1.2.28) from Escherichia coli (strain K12) (see 7 papers)
YJHH_ECOLI / P39359 Probable 2-dehydro-3-deoxy-D-pentonate aldolase YjhH; EC 4.1.2.28 from Escherichia coli (strain K12) (see paper)
23% identity, 78% coverage of query (66.2 bits)
DAPA_METJA / Q57695 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see paper)
25% identity, 83% coverage of query (62.4 bits)
5ktlA / Q3M723 Dihydrodipicolinate synthase from the industrial and evolutionarily important cyanobacteria anabaena variabilis. (see paper)
27% identity, 97% coverage of query (61.2 bits)
Q3M723 4-hydroxy-tetrahydrodipicolinate reductase (EC 1.17.1.8) from Trichormus variabilis (see paper)
27% identity, 97% coverage of query (60.8 bits)
4fhaA Structure of dihydrodipicolinate synthase from streptococcus pneumoniae,bound to pyruvate and lysine
26% identity, 82% coverage of query (60.8 bits)
NSAE_SPHXE / Q9X9Q6 Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase; THBPA hydratase-aldolase; 2'-hydroxybenzalpyruvate aldolase; EC 4.1.2.45 from Sphingobium xenophagum (see 2 papers)
Q9X9Q6 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase (EC 4.1.2.45) from Sphingobium xenophagum (see paper)
29% identity, 82% coverage of query (60.8 bits)
Pf1N1B4_1110 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) from Pseudomonas fluorescens FW300-N1B4
24% identity, 98% coverage of query (58.9 bits)
PP_3599 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) from Pseudomonas putida KT2440
23% identity, 98% coverage of query (58.2 bits)
Q8NMD2 N-acetylneuraminate lyase (EC 4.1.3.3) from Corynebacterium glutamicum (see paper)
24% identity, 98% coverage of query (57.8 bits)
PS417_04195 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) from Pseudomonas simiae WCS417
24% identity, 97% coverage of query (57.4 bits)
HSERO_RS15785 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) from Herbaspirillum seropedicae SmR1
25% identity, 98% coverage of query (56.6 bits)
Q7D3Z9 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
24% identity, 75% coverage of query (56.6 bits)
5c55A / Q8NMD2 Crystal structure of the y138f mutant of c.Glutamicum n- acetylneuraminic acid lyase in complex with pyruvate
24% identity, 98% coverage of query (56.6 bits)
NAHE1_PSEPU / Q51947 Trans-O-hydroxybenzylidenepyruvate hydratase-aldolase; THBPA hydratase-aldolase; 2'-hydroxybenzalpyruvate aldolase; EC 4.1.2.45 from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 2 papers)
Q51947 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase (EC 4.1.2.45) from Pseudomonas putida (see 3 papers)
nahE / AAA66357.1 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase from Pseudomonas putida (see 2 papers)
nahE / BAE92162.1 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase NahE from Pseudomonas putida (see 2 papers)
26% identity, 75% coverage of query (55.8 bits)
8do5B / Q0KK75 Crystal structure of nahe in complex with intermediate (r)-4-hydroxy- 4-(2-hydroxyphenyl)-2-iminobutanoate (see paper)
26% identity, 75% coverage of query (55.8 bits)
8u8wA / A0A0H3FJT8 Crystal structure of n-acetylneuraminate lyase (nana) from klebsiella aerogenes (pyruvate and halides bound)
23% identity, 96% coverage of query (55.5 bits)
Npl / b3225 N-acetylneuraminate lyase (EC 4.1.3.3) from Escherichia coli K-12 substr. MG1655 (see 21 papers)
nanA / P0A6L4 N-acetylneuraminate lyase (EC 4.1.3.3) from Escherichia coli (strain K12) (see 30 papers)
NANA_ECOLI / P0A6L4 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; NALase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Escherichia coli (strain K12) (see 4 papers)
P0A6L4 N-acetylneuraminate lyase (EC 4.1.3.3) from Escherichia coli (see 4 papers)
nanA N-acetylneuraminate lyase; EC 4.1.3.3 from Escherichia coli K12 (see 6 papers)
24% identity, 98% coverage of query (54.3 bits)
2wpbA / P0A6L4 Crystal structure of the e192n mutant of e. Coli n-acetylneuraminic acid lyase in complex with pyruvate and the inhibitor (2r,3r)-2,3,4- trihydroxy-n,n-dipropylbutanamide in space group p21 crystal form i (see paper)
24% identity, 98% coverage of query (54.3 bits)
Q8A3Z0 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Bacteroides thetaiotaomicron (see paper)
25% identity, 96% coverage of query (54.3 bits)
3lbcD D-sialic acid aldolase complexed with l-arabinose
24% identity, 98% coverage of query (54.3 bits)
5j5dA / P9WP25 Crystal structure of dihydrodipicolinate synthase from mycobacterium tuberculosis in complex with alpha-ketopimelic acid (see paper)
24% identity, 82% coverage of query (53.9 bits)
3l21B The crystal structure of a dimeric mutant of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis - dhdps- a204r
24% identity, 82% coverage of query (53.9 bits)
1xxxA Crystal structure of dihydrodipicolinate synthase (dapa, rv2753c) from mycobacterium tuberculosis
24% identity, 82% coverage of query (53.9 bits)
DAPA_STAAC / Q5HG25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Staphylococcus aureus (strain COL) (see paper)
Q5HG25 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Staphylococcus aureus (see paper)
22% identity, 84% coverage of query (53.5 bits)
DAPA_MYCTU / P9WP25 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
24% identity, 82% coverage of query (53.5 bits)
3di1B / Q5HG25 Crystal structure of the staphylococcus aureus dihydrodipicolinate synthase-pyruvate complex (see paper)
22% identity, 84% coverage of query (53.5 bits)
1fdzA N-acetylneuraminate lyase in complex with pyruvate via borohydride reduction
24% identity, 98% coverage of query (53.1 bits)
1fdyA N-acetylneuraminate lyase in complex with hydroxypyruvate
24% identity, 98% coverage of query (53.1 bits)
B7WZA5 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) from Comamonas testosteroni (see paper)
24% identity, 99% coverage of query (52.4 bits)
nahE / P0A144 trans-o-hydroxybenzylidenepyruvate hydratase-aldolase (EC 4.1.2.45) from Pseudomonas putida (see 2 papers)
25% identity, 75% coverage of query (51.6 bits)
Ac3H11_603 L-2-keto-3-deoxyarabonate dehydratase (EC 4.2.1.43) from Acidovorax sp. GW101-3H11
27% identity, 82% coverage of query (51.2 bits)
1f74A / P44539 Crystal structure analysis of n-acetylneuraminate lyase from haemophilus influenzae: crystal form ii complexed with 4-deoxy-sialic acid (see paper)
23% identity, 80% coverage of query (50.8 bits)
1f7bA Crystal structure analysis of n-acetylneuraminate lyase from haemophilus influenzae: crystal form ii in complex with 4-oxo-sialic acid
23% identity, 80% coverage of query (50.8 bits)
nanA / Q9S4K9 N-acetylneuraminate lyase (EC 4.1.3.3) from Clostridium perfringens (strain 13 / Type A) (see 6 papers)
nanA / GB|CAA73375.1 N-acetylneuraminate lyase; EC 4.1.3.3 from Clostridium perfringens (see 4 papers)
25% identity, 77% coverage of query (50.4 bits)
4bwlC Structure of the y137a mutant of e. Coli n-acetylneuraminic acid lyase in complex with pyruvate, n-acetyl-d-mannosamine and n- acetylneuraminic acid
24% identity, 98% coverage of query (50.4 bits)
Q9S4K9 N-acetylneuraminate lyase; NAL; Neu5Ac lyase; N-acetylneuraminate pyruvate-lyase; N-acetylneuraminic acid aldolase; Sialate lyase; Sialic acid aldolase; Sialic acid lyase; EC 4.1.3.3 from Clostridium perfringens (strain 13 / Type A)
25% identity, 77% coverage of query (50.4 bits)
nanA sialic acid lyase from Clostridium perfringens (see paper)
25% identity, 77% coverage of query (50.1 bits)
DAPA_STAAR / Q6GH13 4-hydroxy-tetrahydrodipicolinate synthase; HTPA synthase; EC 4.3.3.7 from Staphylococcus aureus (strain MRSA252) (see paper)
Q6GH13 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Staphylococcus aureus (see 2 papers)
22% identity, 84% coverage of query (50.1 bits)
4bwlA Structure of the y137a mutant of e. Coli n-acetylneuraminic acid lyase in complex with pyruvate, n-acetyl-d-mannosamine and n- acetylneuraminic acid
24% identity, 98% coverage of query (50.1 bits)
BPHYT_RS24155 5-dehydro-4-deoxyglucarate dehydratase (EC 4.2.1.41) from Burkholderia phytofirmans PsJN
24% identity, 98% coverage of query (49.3 bits)
1f73A Crystal structure analysis of n-acetylneuraminate lyase from haemophilus influenzae: crystal form iii in complex with sialic acid alditol
23% identity, 80% coverage of query (49.3 bits)
4woqC / D5Q364 Crystal structures of cdnal from clostridium difficile in complex with ketobutyric
21% identity, 80% coverage of query (48.5 bits)
A0A2P1G7E2 N-acetylneuraminate lyase (EC 4.1.3.3) from Mycoplasma sp. (see paper)
26% identity, 79% coverage of query (48.5 bits)
4wozB Crystal structures of cdnal from clostridium difficile in complex with mannosamine
21% identity, 80% coverage of query (48.5 bits)
A9CGZ4 4-hydroxy-tetrahydrodipicolinate synthase (EC 4.3.3.7) from Agrobacterium tumefaciens (see paper)
25% identity, 84% coverage of query (48.1 bits)
2hmcA / A9CGZ4 The crystal structure of dihydrodipicolinate synthase dapa from agrobacterium tumefaciens
25% identity, 84% coverage of query (47.8 bits)
1f7bC Crystal structure analysis of n-acetylneuraminate lyase from haemophilus influenzae: crystal form ii in complex with 4-oxo-sialic acid
23% identity, 80% coverage of query (46.6 bits)
lhpC / Q88NF4 Δ1-pyrroline-4-hydroxy-2-carboxylate deaminase subunit (EC 3.5.4.22) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 2 papers)
26% identity, 84% coverage of query (45.4 bits)
Or start over
Lawrence Berkeley National Laboratory