Searching for up to 100 curated homologs for AO356_28500 FitnessBrowser__pseudo5_N2C3_1:AO356_28500 (438 a.a.)
Found high-coverage hits (≥70%) to 81 curated proteins.
Removed hits that are identical to the query, leaving 80
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
PS417_10945 Xylose isomerase (EC 5.3.1.5) from Pseudomonas simiae WCS417
91% identity, 100% coverage of query (823 bits)
BPHYT_RS32825 Xylose isomerase (EC 5.3.1.5) from Burkholderia phytofirmans PsJN
72% identity, 100% coverage of query (667 bits)
C7G532 xylose isomerase (EC 5.3.1.5) from Vibrio sp. (see paper)
71% identity, 99% coverage of query (659 bits)
BWI76_RS27025 Xylose isomerase (EC 5.3.1.5) from Klebsiella michiganensis M5al
68% identity, 99% coverage of query (646 bits)
XylA / b3565 xylose isomerase (EC 5.3.1.5) from Escherichia coli K-12 substr. MG1655 (see 38 papers)
xylA / P00944 xylose isomerase (EC 5.3.1.5) from Escherichia coli (strain K12) (see 36 papers)
XYLA_ECOLI / P00944 Xylose isomerase; D-xylulose keto-isomerase; EC 5.3.1.5 from Escherichia coli (strain K12) (see 2 papers)
xylA / GB|AAC76589.1 xylose isomerase; EC 5.3.1.5 from Escherichia coli K12 (see 2 papers)
68% identity, 99% coverage of query (636 bits)
SMc03163 Xylose isomerase (EC 5.3.1.5) from Sinorhizobium meliloti 1021
62% identity, 99% coverage of query (561 bits)
PGA1_c14000 Xylose isomerase (EC 5.3.1.5) from Phaeobacter inhibens BS107
60% identity, 99% coverage of query (530 bits)
Echvi_1876 Xylose isomerase (EC 5.3.1.5) from Echinicola vietnamensis KMM 6221, DSM 17526
51% identity, 99% coverage of query (474 bits)
D2DK62 xylose isomerase (EC 5.3.1.5) from Thermoanaerobacter ethanolicus (see paper)
50% identity, 100% coverage of query (473 bits)
D9SR73 xylose isomerase (EC 5.3.1.5) from Clostridium cellulovorans (see paper)
51% identity, 99% coverage of query (460 bits)
xylA / AAB06798.1 xylose isomerase from Thermotoga neapolitana (see paper)
50% identity, 99% coverage of query (460 bits)
1a0eA / P45687 Xylose isomerase from thermotoga neapolitana
50% identity, 99% coverage of query (459 bits)
1a0cA / P19148 Xylose isomerase from thermoanaerobacterium thermosulfurigenes
49% identity, 99% coverage of query (458 bits)
XYLA_THESA / P30435 Xylose isomerase; EC 5.3.1.5 from Thermoanaerobacterium saccharolyticum (see paper)
AAA03088.1 xylose isomerase from Thermoanaerobacterium saccharolyticum (see paper)
48% identity, 99% coverage of query (454 bits)
B7SLY1 xylose isomerase (EC 5.3.1.5) from Orpinomyces sp. (see 2 papers)
49% identity, 99% coverage of query (450 bits)
xylA / AAC44473.1 xylose isomerase from Thermoanaerobacterium sp (see paper)
48% identity, 99% coverage of query (449 bits)
5nh4A / Q9P8C9 Crystal structure of xylose isomerase from piromyces e2 in complex with one mg2+ ions and glycerol (see paper)
49% identity, 99% coverage of query (439 bits)
Q9P8C9 xylose isomerase (EC 5.3.1.5) from Piromyces sp. E2 (see paper)
49% identity, 99% coverage of query (439 bits)
5nhcA Crystal structure of xylose isomerase from piromyces e2 in complex with two co2+ ions and xylulose
49% identity, 99% coverage of query (439 bits)
5nhaA Crystal structure of xylose isomerase from piromyces sp. E2 in complex with two mn2+ ions and sorbitol
49% identity, 99% coverage of query (439 bits)
5nh9A Crystal structure of xylose isomerase from piromyces e2 in complex with two mn2+ ions and xylose
49% identity, 99% coverage of query (439 bits)
5nh7A Crystal structure of xylose isomerase from piromyces e2 in complex with two mg2+ ions and xylose
49% identity, 99% coverage of query (439 bits)
5nh6A Crystal structure of xylose isomerase from piromyces e2 complexed with one mg2+ ion and xylitol
49% identity, 99% coverage of query (439 bits)
5nh5A Crystal structure of native xylose isomerase from piromyces e2
49% identity, 99% coverage of query (439 bits)
5yn3A Crystal structure of xylose isomerase from piromyces sp. E2
49% identity, 99% coverage of query (439 bits)
Q8A9M2 xylose isomerase (EC 5.3.1.5) from Bacteroides thetaiotaomicron (see paper)
50% identity, 99% coverage of query (435 bits)
4xkmA / Q8A9M2 Crystal structure of xylose isomerase from an human intestinal tract microbe bacteroides thetaiotaomicron
50% identity, 99% coverage of query (434 bits)
xylA / AAA99461.1 xylose isomerase from Bacillus sp. (see paper)
50% identity, 100% coverage of query (434 bits)
1a0dA / P54273 Xylose isomerase from bacillus stearothermophilus
50% identity, 99% coverage of query (431 bits)
xylA / G2TH70 xylA (EC 5.3.1.5) from Weizmannia coagulans 36D1 (see paper)
49% identity, 100% coverage of query (423 bits)
XYLA_LEVBR / P29443 Xylose isomerase; EC 5.3.1.5 from Levilactobacillus brevis (Lactobacillus brevis) (see paper)
44% identity, 99% coverage of query (399 bits)
6intA / A0A4V8H014 Xylose isomerase from paenibacillus sp. R4 (see paper)
44% identity, 99% coverage of query (390 bits)
A1A0H0 xylose isomerase (EC 5.3.1.5) from Bifidobacterium adolescentis (see paper)
43% identity, 97% coverage of query (373 bits)
Build an alignment for AO356_28500 and 33 homologs with ≥ 30% identity
Or download the sequences
1xycA X-ray crystallographic structures of d-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis
27% identity, 89% coverage of query (103 bits)
1xybA X-ray crystallographic structures of d-xylose isomerase-substrate complexes position the substrate and provide evidence for metal movement during catalysis
27% identity, 89% coverage of query (103 bits)
2gyiA Design, synthesis, and characterization of a potent xylose isomerase inhibitor, d-threonohydroxamic acid, and high-resolution x-ray crystallographic structure of the enzyme-inhibitor complex
27% identity, 89% coverage of query (102 bits)
1s5mA Xylose isomerase in substrate and inhibitor michaelis states: atomic resolution studies of a metal-mediated hydride shift
27% identity, 89% coverage of query (102 bits)
1muwA The 0.86 angstrom structure of xylose isomerase
27% identity, 89% coverage of query (102 bits)
9xiaA X-ray analysis of d-xylose isomerase at 1.9 angstroms: native enzyme in complex with substrate and with a mechanism-designed inactivator
27% identity, 77% coverage of query (102 bits)
1xieA Modes of binding substrates and their analogues to the enzyme d-xylose isomerase
27% identity, 77% coverage of query (102 bits)
1xidA Modes of binding substrates and their analogues to the enzyme d-xylose isomerase
27% identity, 77% coverage of query (102 bits)
1xiiA Modes of binding substrates and their analogues to the enzyme d-xylose isomerase
27% identity, 77% coverage of query (101 bits)
1xihA Modes of binding substrates and their analogues to the enzyme d-xylose isomerase
27% identity, 77% coverage of query (101 bits)
1xicA Modes of binding substrates and their analogues to the enzyme d-xylose isomerase
27% identity, 77% coverage of query (101 bits)
1gw9A Tri-iodide derivative of xylose isomerase from streptomyces rubiginosus
27% identity, 77% coverage of query (101 bits)
4j4kA Crystal structure of glucose isomerase
27% identity, 77% coverage of query (101 bits)
8awsA Millisecond cryo-trapping by the spitrobot crystal plunger, xylose isomerase with glucose at 50ms
27% identity, 77% coverage of query (101 bits)
3u3hA X-ray crystallographic analysis of d-xylose isomerase-catalyzed isomerization of (r)-glyceraldehyde
27% identity, 77% coverage of query (101 bits)
2g4jA Anomalous substructure of glucose isomerase
27% identity, 77% coverage of query (101 bits)
1oadA Glucose isomerase from streptomyces rubiginosus in p21212 crystal form
27% identity, 77% coverage of query (101 bits)
5y4iA Crystal structure of glucose isomerase in complex with glycerol in one metal binding mode
27% identity, 77% coverage of query (101 bits)
4e3vA Crystal structure of xylose isomerase from streptomyces rubiginosus cryoprotected in proline
27% identity, 77% coverage of query (101 bits)
3xisA A metal-mediated hydride shift mechanism for xylose isomerase based on the 1.6 angstroms streptomyces rubiginosus structures with xylitol and d-xylose
27% identity, 77% coverage of query (101 bits)
8awyA Millisecond cryo-trapping by the spitrobot crystal plunger, serial measurement xylose isomerase with 2,3-butanediol at 50ms
27% identity, 77% coverage of query (101 bits)
4zb0A A dehydrated form of glucose isomerase collected at room temperature.
27% identity, 77% coverage of query (101 bits)
P24300 xylose isomerase (EC 5.3.1.5) from Streptomyces rubiginosus (see 8 papers)
4duoA / P24300 Room-temperature x-ray structure of d-xylose isomerase in complex with 2mg2+ ions and xylitol at ph 7.7 (see paper)
27% identity, 77% coverage of query (100 bits)
4qehA Room temperature x-ray structure of d-xylose isomerase in complex with two mg2+ ions and l-ribose
27% identity, 77% coverage of query (100 bits)
4qeeA Room temperature x-ray structure of d-xylose isomerase in complex with two ni2+ ions and l-ribose
27% identity, 77% coverage of query (100 bits)
4qe4A Room temperature x-ray structure of d-xylose isomerase in complex with two ni2+ ions and l-ribulose
27% identity, 77% coverage of query (100 bits)
4qe1A Room temperature x-ray structure of d-xylose isomerase in complex with two cd2+ ions and l-ribulose
27% identity, 77% coverage of query (100 bits)
4qdwA Joint x-ray and neutron structure of streptomyces rubiginosus d-xylose isomerase in complex with two ni2+ ions and linear l-arabinose
27% identity, 77% coverage of query (100 bits)
4qdpA Joint x-ray and neutron structure of streptomyces rubiginosus d-xylose isomerase in complex with two cd2+ ions and cyclic beta-l-arabinose
27% identity, 77% coverage of query (100 bits)
3qzaA Joint neutron and x-ray structure of apo-d-xylose isomerase at ph=5.9
27% identity, 77% coverage of query (100 bits)
3kbnA Room temperature structure of d-xylose isomerase in complex with 2ni(2+) co-factors and d12-d-glucose in the linear form
27% identity, 77% coverage of query (100 bits)
3kbmA Room temperature x-ray structure of d-xylose isomerase complexed with 2cd(2+) co-factors and d12-d-alpha-glucose in the cyclic form
27% identity, 77% coverage of query (100 bits)
P26997 xylose isomerase (EC 5.3.1.5) from Thermus thermophilus (see paper)
26% identity, 78% coverage of query (99.4 bits)
1clkA Crystal structure of streptomyces diastaticus no.7 strain m1033 xylose isomerase at 1.9 a resolution with pseudo-i222 space group
26% identity, 87% coverage of query (99.0 bits)
1didA / P12070 Observations of reaction intermediates and the mechanism of aldose- ketose interconversion by d-xylose isomerase (see paper)
27% identity, 76% coverage of query (90.9 bits)
P12070 Xylose isomerase; EC 5.3.1.5 from Arthrobacter sp. (strain NRRL B3728)
27% identity, 76% coverage of query (90.9 bits)
1xllA Mechanism for aldose-ketose interconversion by d-xylose isomerase involving ring opening followed by a 1,2-hydride shift
27% identity, 76% coverage of query (90.9 bits)
1xliA Mechanism for aldose-ketose interconversion by d-xylose isomerase involving ring opening followed by a 1,2-hydride shift
27% identity, 76% coverage of query (90.9 bits)
1xlfA Mechanism for aldose-ketose interconversion by d-xylose isomerase involving ring opening followed by a 1,2-hydride shift
27% identity, 76% coverage of query (90.9 bits)
1xlcA Mechanism for aldose-ketose interconversion by d-xylose isomerase involving ring opening followed by a 1,2-hydride shift
27% identity, 76% coverage of query (90.9 bits)
1dieA Observations of reaction intermediates and the mechanism of aldose- ketose interconversion by d-xylose isomerase
27% identity, 76% coverage of query (90.9 bits)
4xiaA Structures of d-xylose isomerase from arthrobacter strain b3728 containing the inhibitors xylitol and d-sorbitol at 2.5 angstroms and 2.3 angstroms resolution, respectively
26% identity, 76% coverage of query (88.6 bits)
2xinA Protein engineering of xylose (glucose) isomerase from actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites
25% identity, 74% coverage of query (80.5 bits)
1ximA / P12851 Arginine residues as stabilizing elements in proteins (see paper)
25% identity, 74% coverage of query (78.6 bits)
9ximA Protein engineering of xylose (glucose) isomerase from actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites
25% identity, 74% coverage of query (77.4 bits)
1xinA Protein engineering of xylose (glucose) isomerase from actinoplanes missouriensis. 1. Crystallography and site-directed mutagenesis of metal binding sites
25% identity, 74% coverage of query (75.9 bits)
6n98A / A0A1K2FZ20 Xylose isomerase 1f1 variant from streptomyces sp. F-1 (see paper)
27% identity, 77% coverage of query (73.6 bits)
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