Searching for up to 100 curated homologs for AO356_28690 FitnessBrowser__pseudo5_N2C3_1:AO356_28690 (513 a.a.)
Found high-coverage hits (≥70%) to 86 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
ILVX_MYCTU / O53554 Putative acetolactate synthase large subunit IlvX; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
O53554 acetolactate synthase (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
45% identity, 100% coverage of query (348 bits)
Build an alignment for AO356_28690 and 1 homologs with ≥ 30% identity
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C5ARG4 indolepyruvate decarboxylase (EC 4.1.1.74) from Methylorubrum extorquens (see paper)
26% identity, 100% coverage of query (145 bits)
dpgB / A3RJV5 benzoylformate decarboxylase monomer (EC 4.1.1.7) from Stutzerimonas stutzeri (see paper)
25% identity, 97% coverage of query (120 bits)
7orxCCC / Q0SCE8 jostii RHA1 thiamine diphosphate-dependent 4-hydroxybenzoylformate decarboxylase
26% identity, 97% coverage of query (118 bits)
4q9dB / A0QSU7 X-ray structure of a putative thiamin diphosphate-dependent enzyme isolated from mycobacterium smegmatis (see paper)
26% identity, 96% coverage of query (118 bits)
6a50A Structure of benzoylformate decarboxylases in complex with cofactor tpp
25% identity, 97% coverage of query (116 bits)
mdlC / P20906 MdlC (EC 4.1.1.7) from Pseudomonas putida (see 2 papers)
P20906 benzoylformate decarboxylase (EC 4.1.1.7) from Pseudomonas putida (see 16 papers)
25% identity, 97% coverage of query (115 bits)
3fznA Intermediate analogue in benzoylformate decarboxylase
25% identity, 97% coverage of query (115 bits)
1bfdA Benzoylformate decarboxylase from pseudomonas putida
25% identity, 97% coverage of query (115 bits)
3f6bX Crystal structure of benzoylformate decarboxylase in complex with the pyridyl inhibitor paa
25% identity, 97% coverage of query (115 bits)
5deiA Benzoylformate decarboxylase from pseudomonas putida
25% identity, 97% coverage of query (115 bits)
3fsjX Crystal structure of benzoylformate decarboxylase in complex with the inhibitor mbp
25% identity, 97% coverage of query (115 bits)
1mczA Benzoylformate decarboxylase from pseudomonas putida complexed with an inhibitor, r-mandelate
25% identity, 97% coverage of query (115 bits)
1pi3A E28q mutant benzoylformate decarboxylase from pseudomonas putida
24% identity, 97% coverage of query (114 bits)
6qsiA / Q4KB02 Pseudomonas fluorescens pf-5 thiamine diphosphate-dependent 4- hydroxybenzoylformate decarboxylase (see paper)
27% identity, 97% coverage of query (108 bits)
bfd / CAK95977.1 benzoylformate decarboxylase from Pseudomonas putida (see paper)
26% identity, 97% coverage of query (104 bits)
ILVG_ECOLI / P0DP90 Acetolactate synthase isozyme 2 large subunit; AHAS-II; ALS-II; Acetohydroxy-acid synthase II large subunit; EC 2.2.1.6 from Escherichia coli (strain K12) (see 2 papers)
ilvG / GB|CAA28573.1 acetolactate synthase isozyme 2 large subunit; EC 2.2.1.6 from Escherichia coli K12 (see 8 papers)
24% identity, 100% coverage of query (103 bits)
bfd / CAK95976.1 benzoylformate decarboxylase from Pseudomonas putida (see paper)
26% identity, 96% coverage of query (102 bits)
IlvB / b3671 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
ilvB / P08142 acetohydroxy acid synthase I subunit IlvB (EC 2.2.1.6) from Escherichia coli (strain K12) (see 4 papers)
P08142 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Escherichia coli (see paper)
22% identity, 100% coverage of query (80.1 bits)
Q8U2A4 acetolactate synthase (EC 2.2.1.6) from Pyrococcus furiosus (see paper)
22% identity, 100% coverage of query (77.4 bits)
A5X300 acetolactate synthase (EC 2.2.1.6) from Oryza sativa Indica Group (see paper)
25% identity, 99% coverage of query (77.0 bits)
ILVB_ARATH / P17597 Acetolactate synthase, chloroplastic; AtALS; Acetohydroxy-acid synthase; Protein CHLORSULFURON RESISTANT 1; EC 2.2.1.6 from Arabidopsis thaliana (Mouse-ear cress) (see 16 papers)
P17597 acetolactate synthase (EC 2.2.1.6) from Arabidopsis thaliana (see 8 papers)
23% identity, 99% coverage of query (74.7 bits)
7tzzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase p197t mutant in complex with bispyribac-sodium
23% identity, 99% coverage of query (74.7 bits)
4k9qA / A4SXU0 The crystal structure of benzoylformate decarboxylase from polynucleobacter necessarius
25% identity, 95% coverage of query (74.3 bits)
5k2oA / P17597 Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, pyrithiobac (see paper)
23% identity, 99% coverage of query (74.3 bits)
Q6K2E8 acetolactate synthase (EC 2.2.1.6) from Oryza sativa (see paper)
25% identity, 99% coverage of query (74.3 bits)
8et4A Crystal structure of wild-type arabidopsis thaliana acetohydroxyacid synthase in complex with amidosulfuron
23% identity, 99% coverage of query (74.3 bits)
5wj1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a triazolopyrimidine herbicide, penoxsulam
23% identity, 99% coverage of query (74.3 bits)
5k6tA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, propoxycarbazone-sodium
23% identity, 99% coverage of query (74.3 bits)
5k6rA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylamino-carbonyl-triazolinone herbicide, thiencarbazone-methyl
23% identity, 99% coverage of query (74.3 bits)
1z8nA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with an imidazolinone herbicide, imazaquin
23% identity, 99% coverage of query (74.3 bits)
1yi1A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, tribenuron methyl
23% identity, 99% coverage of query (74.3 bits)
1yi0A Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, sulfometuron methyl
23% identity, 99% coverage of query (74.3 bits)
1yhzA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, chlorsulfuron
23% identity, 99% coverage of query (74.3 bits)
1yhyA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide, metsulfuron methyl
23% identity, 99% coverage of query (74.3 bits)
1ybhA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a sulfonylurea herbicide chlorimuron ethyl
23% identity, 99% coverage of query (74.3 bits)
V5Q0Z4 acetolactate synthase (EC 2.2.1.6) from Myosoton aquaticum (see paper)
23% identity, 99% coverage of query (73.9 bits)
5k3sA Crystal structure of arabidopsis thaliana acetohydroxyacid synthase in complex with a pyrimidinyl-benzoate herbicide, bispyribac-sodium
23% identity, 99% coverage of query (73.9 bits)
3ea4A Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron-ester
23% identity, 99% coverage of query (73.9 bits)
3e9yA Arabidopsis thaliana acetohydroxyacid synthase in complex with monosulfuron
23% identity, 99% coverage of query (73.9 bits)
6lpiB / P08142 Crystal structure of ahas holo-enzyme (see paper)
22% identity, 94% coverage of query (73.6 bits)
Q5M4L0 acetolactate synthase (EC 2.2.1.6) from Streptococcus thermophilus (see paper)
22% identity, 100% coverage of query (73.2 bits)
Q42768 acetolactate synthase (EC 2.2.1.6) from Gossypium hirsutum (see paper)
23% identity, 99% coverage of query (72.8 bits)
Q5VB42 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
22% identity, 99% coverage of query (72.0 bits)
Q836A5 acetolactate synthase (EC 2.2.1.6) from Enterococcus faecalis (see 2 papers)
21% identity, 99% coverage of query (71.6 bits)
A0A0M3TGF7 acetolactate synthase (EC 2.2.1.6) from Poa annua (see paper)
25% identity, 99% coverage of query (70.9 bits)
A0A0M4NDK0 acetolactate synthase (EC 2.2.1.6) from Poa annua (see paper)
25% identity, 99% coverage of query (70.9 bits)
SYNPCC7002_A2770 / B1XMM5 2-oxoglutarate decarboxylase monomer (EC 4.1.1.71) from Synechococcus sp. (strain ATCC 27264 / PCC 7002 / PR-6) (see 2 papers)
B1XMM5 oxoglutarate dehydrogenase (succinyl-transferring) (EC 1.2.4.2) from Synechococcus sp. PCC 7002 (see paper)
23% identity, 99% coverage of query (68.9 bits)
Q5VB49 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
23% identity, 99% coverage of query (68.9 bits)
Q5VB44 acetolactate synthase (EC 2.2.1.6) from Helianthus annuus (see paper)
23% identity, 99% coverage of query (68.2 bits)
4qq8C / Q9F4L3 Crystal structure of the formolase fls in space group p 43 21 2 (see paper)
23% identity, 100% coverage of query (67.8 bits)
P09114 Acetolactate synthase 2, chloroplastic; ALS II; Acetohydroxy-acid synthase II; Acetolactate synthase II; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
23% identity, 99% coverage of query (67.8 bits)
P09342 Acetolactate synthase 1, chloroplastic; ALS I; Acetohydroxy-acid synthase I; Acetolactate synthase I; EC 2.2.1.6 from Nicotiana tabacum (Common tobacco)
23% identity, 99% coverage of query (67.8 bits)
4feeA High-resolution structure of pyruvate oxidase in complex with reaction intermediate 2-hydroxyethyl-thiamin diphosphate carbanion-enamine, crystal b (see paper)
22% identity, 98% coverage of query (67.4 bits)
thzk0150 / BAO66169.1 2-hydroxy-4-methyl-2-(2-phenylacetyl)pentanoic acid synthase from Thermosporothrix hazakensis (see paper)
22% identity, 99% coverage of query (67.4 bits)
1powA The refined structures of a stabilized mutant and of wild-type pyruvate oxidase from lactobacillus plantarum
22% identity, 98% coverage of query (67.4 bits)
K7TWQ8 acetolactate synthase (EC 2.2.1.6) from Zea mays (see paper)
24% identity, 99% coverage of query (67.0 bits)
ILVB1_MYCTU / P9WG41 Acetolactate synthase large subunit IlvB1; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WG41 acetolactate synthase (subunit 2/2) (EC 2.2.1.6) from Mycobacterium tuberculosis (see paper)
22% identity, 89% coverage of query (67.0 bits)
P37063 pyruvate oxidase (EC 1.2.3.3) from Lactiplantibacillus plantarum (see 2 papers)
22% identity, 98% coverage of query (67.0 bits)
1y9dD / P37063 Pyruvate oxidase variant v265a from lactobacillus plantarum (see paper)
22% identity, 99% coverage of query (66.2 bits)
Hacl1 / Q8CHM7 2-hydroxyacyl-CoA lyase 1 subunit (EC 4.1.2.63) from Rattus norvegicus (see 3 papers)
HACL1_RAT / Q8CHM7 2-hydroxyacyl-CoA lyase 1; 2-hydroxyphytanoyl-CoA lyase; 2-HPCL; Phytanoyl-CoA 2-hydroxylase 2; EC 4.1.2.63 from Rattus norvegicus (Rat) (see paper)
Q8CHM7 2-hydroxyacyl-CoA lyase (EC 4.1.2.63) from Rattus norvegicus (see 5 papers)
21% identity, 100% coverage of query (66.2 bits)
2ezuA Pyruvate oxidase variant f479w in complex with reaction intermediate 2-acetyl-thiamin diphosphate
22% identity, 98% coverage of query (66.2 bits)
2ez9A Pyruvate oxidase variant f479w in complex with reaction intermediate analogue 2-phosphonolactyl-thiamin diphosphate
22% identity, 98% coverage of query (66.2 bits)
2ez8A Pyruvate oxidase variant f479w in complex with reaction intermediate 2-lactyl-thiamin diphosphate
22% identity, 98% coverage of query (66.2 bits)
2ez4B Pyruvate oxidase variant f479w
22% identity, 98% coverage of query (66.2 bits)
3d7kA Crystal structure of benzaldehyde lyase in complex with the inhibitor mbp
24% identity, 100% coverage of query (65.9 bits)
als / Q7DAV2 α-acetolactate synthase subunit (EC 2.2.1.6) from Lactococcus lactis subsp. lactis (strain IL1403) (see 2 papers)
Q7DAV2 acetolactate synthase (EC 2.2.1.6) from Lactococcus lactis (see paper)
22% identity, 100% coverage of query (65.1 bits)
5dx6B / P27696 Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
21% identity, 99% coverage of query (64.7 bits)
ilvB / AAB38426.1 acetolactate synthase from Mycobacterium avium (see paper)
22% identity, 89% coverage of query (62.0 bits)
1ozgA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactor and with an unusual intermediate
21% identity, 99% coverage of query (61.2 bits)
Q5S3P7 acetolactate synthase (EC 2.2.1.6) from Streptomyces cinnamonensis (see 2 papers)
ilvB / AAV52901.1 acetohydroxy acid synthase large subunit from Streptomyces cinnamonensis (see paper)
21% identity, 98% coverage of query (60.8 bits)
budB / P27696 catabolic acetolactate synthase (EC 2.2.1.6) from Klebsiella pneumoniae (see 2 papers)
21% identity, 99% coverage of query (60.5 bits)
5dx6A Acetolactate synthase from klebsiella pneumoniae soaked with beta- fluoropyruvate
21% identity, 99% coverage of query (60.5 bits)
HACL1 / Q9UJ83 2-hydroxyacyl-CoA lyase 1 (EC 4.1.2.63) from Homo sapiens (see 7 papers)
HACL1_HUMAN / Q9UJ83 2-hydroxyacyl-CoA lyase 1; 2-hydroxyphytanoyl-CoA lyase; 2-HPCL; Phytanoyl-CoA 2-hydroxylase 2; EC 4.1.2.63 from Homo sapiens (Human) (see 3 papers)
Q9UJ83 2-hydroxyacyl-CoA lyase (EC 4.1.2.63) from Homo sapiens (see 3 papers)
21% identity, 100% coverage of query (59.7 bits)
1ozfA The crystal structure of klebsiella pneumoniae acetolactate synthase with enzyme-bound cofactors
21% identity, 99% coverage of query (59.7 bits)
A4YXN1 oxalyl-CoA decarboxylase (EC 4.1.1.8) from Bradyrhizobium japonicum (see paper)
22% identity, 99% coverage of query (59.3 bits)
HACL1_MOUSE / Q9QXE0 2-hydroxyacyl-CoA lyase 1; 2-hydroxyphytanoyl-CoA lyase; 2-HPCL; Phytanoyl-CoA 2-hydroxylase 2; EC 4.1.2.63 from Mus musculus (Mouse) (see 2 papers)
Q9QXE0 2-hydroxyacyl-CoA lyase (EC 4.1.2.63) from Mus musculus (see 2 papers)
21% identity, 100% coverage of query (58.9 bits)
5d6rB Acetolactate synthase from klebsiella pneumoniae in complex with mechanism-based inhibitor
21% identity, 99% coverage of query (58.9 bits)
5wdgA Acetolactate synthase from klebsiella pneumoniae in complex with a reaction intermediate
21% identity, 99% coverage of query (58.5 bits)
P42463 acetolactate synthase (EC 2.2.1.6) from Corynebacterium glutamicum (see paper)
21% identity, 87% coverage of query (58.2 bits)
4rjiC Acetolactate synthase from bacillus subtilis bound to thdp - crystal form i (see paper)
20% identity, 99% coverage of query (58.2 bits)
4rjkF Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
20% identity, 99% coverage of query (58.2 bits)
ILVG_MYCTU / P9WG39 Acetolactate synthase large subunit IlvG; ALS; Acetohydroxy-acid synthase large subunit; AHAS; EC 2.2.1.6 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
P9WG39 acetolactate synthase (EC 2.2.1.6) from Mycobacterium tuberculosis (see 2 papers)
23% identity, 100% coverage of query (57.8 bits)
4rjkG Acetolactate synthase from bacillus subtilis bound to lthdp - crystal form ii
20% identity, 99% coverage of query (57.8 bits)
6xn8A / A0A1H8YFL8 Crystal structure of 2-hydroxyacyl coa lyase (hacl) from rhodospirillales bacterium urhd0017
22% identity, 100% coverage of query (53.9 bits)
5npuA Inferred ancestral pyruvate decarboxylase (see paper)
23% identity, 97% coverage of query (53.1 bits)
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Lawrence Berkeley National Laboratory