Searching for up to 100 curated homologs for AO356_29245 FitnessBrowser__pseudo5_N2C3_1:AO356_29245 (447 a.a.)
Found high-coverage hits (≥70%) to 52 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 2.A.1.15.5 / O30513 Benzoate porter, BenK from Acinetobacter calcoaceticus (see 2 papers)
42% identity, 97% coverage of query (371 bits)
TC 2.A.1.15.7 / Q6FBB3 Aromatic compound (benzoate) uptake transporter of 450 aas from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1)
41% identity, 97% coverage of query (337 bits)
PCAK_ACIAD / Q43975 4-hydroxybenzoate transporter PcaK; 4-HB transporter from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
31% identity, 87% coverage of query (196 bits)
Build an alignment for AO356_29245 and 3 homologs with ≥ 30% identity
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NIAP_ACIAD / Q6FFF7 Niacin transporter NiaP from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
28% identity, 94% coverage of query (192 bits)
genK / Q8NLB7 gentisate transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see 3 papers)
GENK_CORGL / Q8NLB7 Gentisate transporter from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / BCRC 11384 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
31% identity, 89% coverage of query (186 bits)
TC 2.A.1.15.3 / Q46M63 2,4-Dichlorophenoxyacetate porter (see 5 papers)
32% identity, 96% coverage of query (185 bits)
GALT_PSEPU / E8ZB61 Gallate transporter; Gallate permease from Pseudomonas putida (Arthrobacter siderocapsulatus) (see paper)
galT / CBJ94499.1 gallic acid permease from Pseudomonas putida (see paper)
30% identity, 89% coverage of query (177 bits)
proT / BAB32694.1 putative transporter from Pseudomonas straminea (see 2 papers)
29% identity, 96% coverage of query (176 bits)
PCAK_PSEPU / Q51955 4-hydroxybenzoate transporter PcaK from Pseudomonas putida (Arthrobacter siderocapsulatus) (see 3 papers)
TC 2.A.1.15.1 / Q51955 4-Hydroxybenzoate/protocatechuate porter from Pseudomonas putida (see paper)
pcaK / AAA85137.1 PcaK from Pseudomonas putida (see paper)
29% identity, 96% coverage of query (168 bits)
TC 2.A.1.15.6 / O24842 Vanillate porter, VanK (see 4 papers)
30% identity, 87% coverage of query (165 bits)
MHBT_KLEOX / Q5EXK5 3-hydroxybenzoate transporter MhbT from Klebsiella oxytoca (see paper)
28% identity, 94% coverage of query (162 bits)
TC 2.A.1.15.14 / Q8VUZ0 Probable uptake transporter for 2,4-dichlorophenoxyacetic acid (2,4-D), CadK from Bradyrhizobium sp. HW13
29% identity, 92% coverage of query (159 bits)
TC 2.A.1.15.4 / P94131 cis,cis-muconate porter, MucK from Acinetobacter calcoaceticus (see 2 papers)
mucK / AAC27117.1 cis,cis-muconate transport protein MucK from Acinetobacter baylyi (see paper)
29% identity, 83% coverage of query (143 bits)
YaiK / b0353 3-hydroxyphenylpropionate/3-hydroxycinnamate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpT / P77589 3-hydroxyphenylpropionate/3-hydroxycinnamate:H+ symporter from Escherichia coli (strain K12) (see 2 papers)
MHPT_ECOLI / P77589 3-(3-hydroxy-phenyl)propionate transporter; 3HPP transporter; 3-(3-hydroxy-phenyl)propionate:H(+) symporter; 3HPP:H(+) symporter from Escherichia coli (strain K12) (see 2 papers)
TC 2.A.1.15.2 / P77589 MhpT. A specific 3-(3-hydroxyphenyl)propionate (3HPP) transporter; vital for E. coli K-12 W3110 to grow on this substrate from Escherichia coli (see 3 papers)
30% identity, 92% coverage of query (138 bits)
NIAP_BACSU / O34691 Putative niacin/nicotinamide transporter NiaP from Bacillus subtilis (strain 168) (see paper)
TC 2.A.1.82.4 / O34691 Niacin uptake porter NiaP from Bacillus subtilis (see 2 papers)
26% identity, 91% coverage of query (131 bits)
YaaU / b0045 putative transporter YaaU from Escherichia coli K-12 substr. MG1655 (see 4 papers)
28% identity, 95% coverage of query (127 bits)
TC 2.A.1.15.11 / Q6M372 The Vanillate porter, VanK from Corynebacterium glutamicum (strain ATCC 13032 / DSM 20300 / JCM 1318 / LMG 3730 / NCIMB 10025) (see paper)
27% identity, 93% coverage of query (127 bits)
YgcS / b2771 putative transporter YgcS from Escherichia coli K-12 substr. MG1655 (see 2 papers)
TC 2.A.1.1.95 / Q46909 Inner membrane metabolite transport protein YgcS from Escherichia coli (strain K12) (see 3 papers)
30% identity, 88% coverage of query (119 bits)
NanX / b4279 sialic acid transporter NanX from Escherichia coli K-12 substr. MG1655 (see 5 papers)
nanX / P39352 sialic acid transporter NanX from Escherichia coli (strain K12) (see 4 papers)
YJHB_ECOLI / P39352 Putative metabolite transport protein YjhB from Escherichia coli (strain K12) (see paper)
26% identity, 82% coverage of query (114 bits)
TC 2.A.1.15.8 / O24723 Probable 1-hydroxy-2-naphthoate transporter, orf1 (see paper)
25% identity, 89% coverage of query (99.4 bits)
NanT / b3224 N-acetylneuraminate:H+ symporter from Escherichia coli K-12 substr. MG1655 (see 10 papers)
nanT / P41036 N-acetylneuraminate:H+ symporter from Escherichia coli (strain K12) (see 16 papers)
NANT_ECOLI / P41036 Sialic acid transporter NanT; Sialic acid permease; Sialic acid/H(+) symporter from Escherichia coli (strain K12) (see 4 papers)
TC 2.A.1.12.1 / P41036 The sialic acid porter, NanT. N-acetylneuraminic acid (Neu5Ac) serves as a sole source of carbon and nitrogen for E. coli. It is a mucus-derived carbon source in the mammalian gut. NanT can also take up and allow efficient growth on the related sialic acids, N-glycolylneuraminic acid (Neu5Gc) and 3-keto-3-deoxy-d-glycero-d-galactonononic acid (KDN) from Escherichia coli (see 4 papers)
24% identity, 87% coverage of query (93.6 bits)
SVOP_BOVIN / Q1JP63 Synaptic vesicle 2-related protein; SV2-related protein from Bos taurus (Bovine) (see paper)
22% identity, 81% coverage of query (93.2 bits)
SVOP_XENLA / Q2XWK0 Synaptic vesicle 2-related protein; SV2-related protein from Xenopus laevis (African clawed frog) (see paper)
22% identity, 81% coverage of query (91.7 bits)
TC 2.A.1.82.1 / F2CRE4 The barley copper uptake porter, CT-1 of 749 aas; nearly identical to the wheat orthologue from Hordeum vulgare var. distichum
24% identity, 87% coverage of query (88.2 bits)
SVOP_RAT / Q9Z2I7 Synaptic vesicle 2-related protein; SV2-related protein from Rattus norvegicus (Rat) (see paper)
22% identity, 86% coverage of query (85.9 bits)
TC 2.A.1.1.120 / E1WAV3 Major myo-inositol transporter, IolT1, of 456 aas from Salmonella typhimurium (strain SL1344)
24% identity, 79% coverage of query (85.5 bits)
TC 2.A.1.82.3 / Q8BFT9 Synaptic vesicle 2-related protein (SV2-related protein), SVOP from Mus musculus (see 4 papers)
22% identity, 86% coverage of query (85.5 bits)
TC 2.A.1.15.9 / O51798 Probable 4-methylmuconolactone transporter, MmlH from Ralstonia eutropha (strain JMP134) (Alcaligenes eutrophus) (see paper)
23% identity, 82% coverage of query (83.6 bits)
CCNA_00857 D-xylose transporter from Caulobacter crescentus NA1000
23% identity, 86% coverage of query (80.5 bits)
Ga0059261_1777 D-fructose transporter, sugar porter family from Sphingomonas koreensis DSMZ 15582
23% identity, 78% coverage of query (79.3 bits)
S22AG_HUMAN / Q86VW1 Solute carrier family 22 member 16; Carnitine transporter 2; CT2; Fly-like putative transporter 2; FLIPT2; Flipt 2; Organic cation transporter OKB1; Organic cation/carnitine transporter 6 from Homo sapiens (Human) (see 7 papers)
TC 2.A.1.19.12 / Q86VW1 The high affinity L-carnitine transporter, CT2, present in the luminal membranes of epididymal epithelia and Sertoli cells of the testis (Enomoto et al., 2002b) (see 9 papers)
28% identity, 74% coverage of query (79.0 bits)
TC 2.A.1.1.53 / Q8NTX0 Myo-Inositol uptake porter, IolT1 (Km=0.2mM) from Corynebacterium glutamicum (Brevibacterium flavum) (see paper)
24% identity, 79% coverage of query (77.8 bits)
TC 2.A.1.1.42 / Q8G3X1 The D-glucose:H+ symporter, GlcP (glucose uptake is inhibited by 2-deoxyglucose, mannose and galactose) from Bifidobacterium longum (see paper)
25% identity, 81% coverage of query (76.3 bits)
S22A6_PSEAM / O57379 Solute carrier family 22 member 6; Organic anion transporter 1; Renal organic anion transporter 1; ROAT1; fROAT1 from Pseudopleuronectes americanus (Winter flounder) (Pleuronectes americanus) (see paper)
24% identity, 74% coverage of query (71.6 bits)
PHO84 / P25297 phosphate transporter phoT from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see 76 papers)
PHO84_YEAST / P25297 Inorganic phosphate transporter PHO84 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P25297 ABC-type phosphate transporter (EC 7.3.2.1) from Saccharomyces cerevisiae (see paper)
TC 2.A.1.9.1 / P25297 High affinity Pi from Saccharomyces cerevisiae (Baker's yeast) (see 7 papers)
PHO84 / GB|CAA89157.1 inorganic phosphate transporter PHO84 from Saccharomyces cerevisiae (see paper)
26% identity, 76% coverage of query (70.9 bits)
8bw7A Cryo-em structure of rat slc22a6 bound to alpha-ketoglutaric acid
23% identity, 74% coverage of query (67.0 bits)
S22A6_MOUSE / Q8VC69 Solute carrier family 22 member 6; Kidney-specific transport protein; Novel kidney transcript; mNKT; Organic anion transporter 1; mOAT1; Renal organic anion transporter 1; mROAT1 from Mus musculus (Mouse) (see 6 papers)
23% identity, 74% coverage of query (64.7 bits)
8bvsA Cryo-em structure of rat slc22a6 bound to tenofovir
23% identity, 74% coverage of query (64.7 bits)
8bvtA / O35956 Cryo-em structure of rat slc22a6 bound to probenecid (see paper)
23% identity, 74% coverage of query (64.3 bits)
Q9VCA2 Organic cation transporter protein from Drosophila melanogaster (Fruit fly)
26% identity, 74% coverage of query (62.0 bits)
S22A6_HUMAN / Q4U2R8 Solute carrier family 22 member 6; Organic anion transporter 1; hOAT1; PAH transporter; hPAHT; Renal organic anion transporter 1; hROAT1 from Homo sapiens (Human) (see 20 papers)
TC 2.A.1.19.31 / Q4U2R8 Solute carrier family 22 member 6 (Organic anion transporter 1) (hOAT1) (PAH transporter) (hPAHT) (Renal organic anion transporter 1) (hROAT1), from Homo sapiens (see 17 papers)
24% identity, 74% coverage of query (62.0 bits)
S22AB_HUMAN / Q9NSA0 Solute carrier family 22 member 11; Organic anion transporter 4; OAT4; Organic anion:dicarboxylate exchanger OAT4 from Homo sapiens (Human) (see 11 papers)
TC 2.A.1.19.10 / Q9NSA0 The apical proximal tubular kidney/placenta organic anion transporter 4, Oat4 (Slc22a11) (transports estrone sulfate (Km = 1 µM), dehydroepiandrosterone sulfate (Km = 60µM), many anionic drugs, diuretics, bile salts, urate and ochratoxin A). Catalyzes Na+-independent efflux, possibly using glutamate as a counter anion in an exchange reaction, especially in the placenta from Homo sapiens (Human) (see 7 papers)
SLC22A11 / GB|BAA95316.1 solute carrier family 22 member 11 from Homo sapiens
23% identity, 82% coverage of query (54.7 bits)
O42885 Putative inorganic phosphate transporter C8E4.01c from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
22% identity, 83% coverage of query (54.3 bits)
S22A7_HUMAN / Q9Y694 Solute carrier family 22 member 7; Novel liver transporter; NLT; Organic anion transporter 2; hOAT2 from Homo sapiens (Human) (see 9 papers)
TC 2.A.1.19.25 / Q9Y694 Solute carrier family 22 member 7 (liver transporter) (Organic anion transporter 2) (hOAT2), transports cyclic nucleotodes and the anti-viral drug, acyclovir (Dahlin et al. 2013). Expressed in liver, kidney, brain and red blood cells from Homo sapiens (see 9 papers)
23% identity, 74% coverage of query (51.2 bits)
S22A2_HUMAN / O15244 Solute carrier family 22 member 2; Organic cation transporter 2; hOCT2 from Homo sapiens (Human) (see 25 papers)
TC 2.A.1.19.30 / O15244 Solute carrier family 22 member 2 (Organic cation transporter 2) (hOCT2) from Homo sapiens (see 23 papers)
23% identity, 76% coverage of query (48.9 bits)
7zhaA / O75751 Structure of human oct3 in complex with inhibitor decynium-22 (see paper)
25% identity, 76% coverage of query (48.5 bits)
YAEC_SCHPO / Q09852 Putative inorganic phosphate transporter C23D3.12 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
24% identity, 84% coverage of query (47.8 bits)
VGLU2_RAT / Q9JI12 Vesicular glutamate transporter 2; VGluT2; Differentiation-associated BNPI; Differentiation-associated Na(+)-dependent inorganic phosphate cotransporter; Solute carrier family 17 member 6 from Rattus norvegicus (Rat) (see 10 papers)
TC 2.A.1.14.16 / Q9JI12 The broad specificity brain synaptic vesicle anion transporter (transports glutamate in a Δψ-dependent fashion requiring Cl- but phosphate by a Na+-dependent mechanism via a different pathway/mechanism from Rattus norvegicus (see 8 papers)
23% identity, 78% coverage of query (47.0 bits)
7t3nA / Q9JI12 R184q/e191q mutant of rat vesicular glutamate transporter 2 (vglut2)
23% identity, 78% coverage of query (47.0 bits)
7zh6A Structure of human oct3 in complex with inhibitor corticosterone
24% identity, 76% coverage of query (46.6 bits)
S22A3_HUMAN / O75751 Solute carrier family 22 member 3; Extraneuronal monoamine transporter; EMT; Organic cation transporter 3; OCT3 from Homo sapiens (Human) (see 11 papers)
TC 2.A.1.19.24 / O75751 Solute carrier family 22 member 3 (Extraneuronal monoamine transporter) (EMT) (Organic cation transporter 3) from Homo sapiens (see 3 papers)
25% identity, 76% coverage of query (45.1 bits)
8et9A / O15244 Cryo-em structure of the organic cation transporter 2 in complex with 1-methyl-4-phenylpyridinium (see paper)
21% identity, 90% coverage of query (44.3 bits)
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Lawrence Berkeley National Laboratory