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Searching for up to 100 curated homologs for AZOBR_RS00065 FitnessBrowser__azobra:AZOBR_RS00065 (276 a.a.)

Found high-coverage hits (≥70%) to 41 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

UgpE / b3451 sn-glycerol 3-phosphate ABC transporter membrane subunit UgpE (EC 7.6.2.10) from Escherichia coli K-12 substr. MG1655 (see paper)
UgpE / P10906 sn-glycerol 3-phosphate ABC transporter membrane subunit UgpE (EC 7.6.2.10) from Escherichia coli (strain K12) (see 20 papers)
UGPE_ECOLI / P10906 sn-glycerol-3-phosphate transport system permease protein UgpE from Escherichia coli (strain K12) (see 5 papers)
P10906 ABC-type glycerol 3-phosphate transporter (EC 7.6.2.10) from Escherichia coli (see paper)
TC 3.A.1.1.3 / P10906 UgpE aka B3451, component of Glycerol-phosphate porter. Transports both glycerol-3-P and glycerol-3-P diesters including glycerophosphocholine but not glycerol-2-P from Escherichia coli (see 5 papers)
    57% identity, 100% coverage of query (320 bits)

TC 3.A.1.1.4 / P29824 LacG, component of Lactose porter from Agrobacterium radiobacter (see paper)
    32% identity, 100% coverage of query (144 bits)

G9MB86 ABC-type glycerol 3-phosphate transporter (subunit 1/3) (EC 7.6.2.10) from Thermus thermophilus (see paper)
    38% identity, 78% coverage of query (137 bits)

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Build an alignment for AZOBR_RS00065 and 3 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

ARAQ_BACSU / P94530 Arabinooligosaccharides transport system permease protein AraQ from Bacillus subtilis (strain 168) (see 3 papers)
TC 3.A.1.1.34 / P94530 L-arabinose transport system permease protein AraQ, component of The arabinosaccharide transporter AraNPQMsmX. Transports α-1,5-arabinooligosaccharides, at least up to four L-arabinosyl units; the key transporter for α-1,5-arabinotriose and α-1,5-arabinotetraose, but not for α-1,5-arabinobiose which is transported by AraE. MsmX is also used by the MdxEFG-MsmX system (3.A.1.1.36) (Ferreira and Sá-Nogueira, 2010). Involved in the uptake of pectin oligosaccharides with either MsmX or YurJ as the ATPase from Bacillus subtilis (see 5 papers)
    28% identity, 96% coverage of query (136 bits)

SM_b21654 ABC transporter for Lactose, permease component 2 from Sinorhizobium meliloti 1021
    33% identity, 96% coverage of query (132 bits)

TC 3.A.1.1.50 / Q5SLB5 Sugar ABC transporter, permease protein, component of Probable glycerophosphocholine (GPC) uptake porter (Chandravanshi et al. 2016). The system may include a receptor and three membrane proteins (of 378 aas and 6 TMSs, 299 aas and 7 TMSs, and 113 aas and 3 TMSs (?). The ATPase has not been identified from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
    30% identity, 83% coverage of query (119 bits)

TC 3.A.1.1.39 / Q9WYR1 Alpha-1,4-digalacturonate porter (Nanavati et al., 2006). Regulated by pectin utilization regulon UxaR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    29% identity, 94% coverage of query (113 bits)

TC 3.A.1.1.18 / Q8RJU8 NgcG, component of N-Acetylglucosamine/N,N'-diacetyl chitobiose porter (NgcK (C) not identified) from Streptomyces olivaceoviridis (Streptomyces corchorusii) (see paper)
    28% identity, 98% coverage of query (111 bits)

TC 3.A.1.1.24 / Q72KX4 Sugar transport system permease protein aka TT_C0326, component of The glucose/mannose porter TTC0326-8 plus MalK1 (ABC protein, shared with 3.A.1.1.25) from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
    30% identity, 97% coverage of query (107 bits)

Ac3H11_2065 glucose ABC transporter, permease component 2 from Acidovorax sp. GW101-3H11
    28% identity, 96% coverage of query (106 bits)

TC 3.A.1.1.30 / Q88P36 GtsC (GLcG), component of Glucose porter, GtsABCD from Pseudomonas putida (strain KT2440) (see paper)
    29% identity, 72% coverage of query (106 bits)

PS417_22135 glucose/xylose ABC transporter, permease component 1 from Pseudomonas simiae WCS417
    28% identity, 72% coverage of query (106 bits)

TC 3.A.1.1.23 / Q9X9R5 CBP protein aka CebG, component of The cellobiose/cellotriose (and possibly higher cellooligosaccharides), CebEFGMsiK [MsiK functions to energize several ABC transporters including those for maltose/maltotriose and trehalose] from Streptomyces reticuli (see paper)
    26% identity, 98% coverage of query (105 bits)

TC 3.A.1.1.48 / D6ZW62 Permease of ABC transporter for sugars, component of The lacto-N-biose I (LNB; Gal β-1,3-GlcNAc)/galacto-N-biose (GNB; Gal β-1,3-GalNAc) transporter from Bifidobacterium longum subsp. longum (strain JDM301)
    30% identity, 93% coverage of query (103 bits)

TC 3.A.1.1.20 / Q7WWQ8 Transmembrane permease MsmG, component of The fructooligosaccharide porter, MsmEFGK from Lactobacillus acidophilus (see 2 papers)
msmG / GI|33149340 transmembrane permease MsmG from Lactobacillus acidophilus (see paper)
    25% identity, 79% coverage of query (103 bits)

SMc04257 ABC transporter for D-Cellobiose and D-Salicin, permease component 1 from Sinorhizobium meliloti 1021
    28% identity, 98% coverage of query (99.0 bits)

PfGW456L13_1896 ABC transporter for D-Galactose and D-Glucose, permease component 2 from Pseudomonas fluorescens GW456-L13
    26% identity, 73% coverage of query (98.6 bits)

TC 3.A.1.1.41 / G4FGN6 ABC-type transporter, integral membrane subunit, component of Trehalose porter. Also binds sucrose (Boucher and Noll, 2011). Induced by glucose and trehalose. Directly regulated by trehalose-responsive regulator TreR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
    28% identity, 92% coverage of query (96.7 bits)

smoH / Q7CS31 ABC-type 3-(6-sulfo-α-D-quinovosyl)-sn-glycerol transporter permease subunit from Agrobacterium fabrum (strain C58 / ATCC 33970) (see paper)
    28% identity, 83% coverage of query (94.7 bits)

GGTD_SYNY3 / Q55473 Osmoprotective compounds uptake permease protein GgtD from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
TC 3.A.1.1.32 / Q55473 Membrane bound sugar transport protein, component of The glucosylglycerol uptake transporter (functions in osmoprotection and also transports sucrose and trehalose (Mikkat and Hagemann, 2000) (most similar to 3.A.1.1.8) from Synechocystis sp. (strain PCC 6803) (see paper)
    32% identity, 72% coverage of query (94.4 bits)

TC 3.A.1.1.44 / Q9KZ08 Putative maltose permease, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
    31% identity, 71% coverage of query (94.0 bits)

MALG_THELN / Q7LYX6 Trehalose/maltose transport system permease protein MalG from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 3 papers)
TC 3.A.1.1.7 / O51925 MalG aka PF1741, component of Maltose/trehalose porter (see paper)
    27% identity, 98% coverage of query (94.0 bits)

NGCG_STRCO / O50501 Diacetylchitobiose uptake system permease protein NgcG from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145) (see paper)
    28% identity, 95% coverage of query (92.0 bits)

TC 3.A.1.1.6 / Q48397 CymG, component of Cyclodextrin porter from Klebsiella oxytoca (see paper)
    27% identity, 99% coverage of query (90.9 bits)

PGA1_c27950 N-Acetyl-D-glucosamine ABC transport system, permease component 2 from Phaeobacter inhibens BS107
    26% identity, 98% coverage of query (90.1 bits)

MELC_BACSU / O34518 Melibiose/raffinose/stachyose import permease protein MelC from Bacillus subtilis (strain 168) (see paper)
    29% identity, 83% coverage of query (89.4 bits)

TC 3.A.1.1.26 / O06991 MalG aka yvdI, component of The maltose porter, MdxEFG and MsmX from Bacillus subtilis (see 2 papers)
    28% identity, 80% coverage of query (86.7 bits)

TC 3.A.1.1.12 / Q9AI66 PalG, component of Palatinose (isomaltulose; 6-O-α-D-glucopyranosyl-D-fructose) uptake porter from Erwinia rhapontici (see paper)
    27% identity, 95% coverage of query (85.9 bits)

Q9X2F5 ABC-type maltose transporter (subunit 1/2) (EC 7.5.2.1) from Thermotoga maritima (see paper)
TC 3.A.1.1.22 / Q9X2F5 MalG2; aka Maltose ABC transporter, permease protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
    26% identity, 81% coverage of query (84.0 bits)

SM_b21105 ABC transporter for L-Fucose, permease component 2 from Sinorhizobium meliloti 1021
    29% identity, 74% coverage of query (83.6 bits)

Q9X0S9 ABC-type maltose transporter (subunit 2/2) (EC 7.5.2.1) from Thermotoga maritima (see paper)
TC 3.A.1.1.22 / Q9X0S9 MalG1; aka Maltose ABC transporter, permease protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
    28% identity, 72% coverage of query (80.5 bits)

SMc02871 ABC transporter for N-Acetyl-D-glucosamine, permease protein 2 from Sinorhizobium meliloti 1021
    26% identity, 96% coverage of query (80.5 bits)

BWI76_RS01820 maltose ABC transporter, permease component 2 (MalG) from Klebsiella michiganensis M5al
    27% identity, 96% coverage of query (79.0 bits)

XACI_HALVD / D4GP37 Xylose/arabinose import permease protein XacI from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    23% identity, 93% coverage of query (77.4 bits)

Pf1N1B4_5114 sucrose ABC transporter, permease component 2 from Pseudomonas fluorescens FW300-N1B4
    29% identity, 81% coverage of query (77.4 bits)

MalG / b4032 maltose ABC transporter membrane subunit MalG (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
MalG / P68183 maltose ABC transporter membrane subunit MalG (EC 7.5.2.1) from Escherichia coli (strain K12) (see 6 papers)
MALG_ECOLI / P68183 Maltose/maltodextrin transport system permease protein MalG from Escherichia coli (strain K12) (see 5 papers)
P68183 ABC-type maltose transporter (subunit 2/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68183 Maltose transport system permease protein MalG aka B4032, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 13 papers)
malG / RF|NP_418456 maltose transport system permease protein malG from Escherichia coli K12 (see 15 papers)
    29% identity, 74% coverage of query (77.0 bits)

sugB / P9WG01 ABC-type trehalose transporter integral membrane protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGB_MYCTU / P9WG01 Trehalose transport system permease protein SugB from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
TC 3.A.1.1.31 / O50453 PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGB, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 3 papers)
    28% identity, 73% coverage of query (75.9 bits)

BPHYT_RS16105 ABC transporter for D-Sorbitol, permease component 1 from Burkholderia phytofirmans PsJN
    30% identity, 72% coverage of query (75.5 bits)

TC 3.A.1.1.14 / Q97UF3 AraU, component of Arabinose, fructose, xylose porter from Sulfolobus solfataricus (see paper)
    24% identity, 92% coverage of query (74.7 bits)

TC 3.A.1.1.27 / Q8DT26 MalG, component of Maltose/Maltotriose/maltodextrin (up to 7 glucose units) transporters MalXFGK (MsmK (3.A.1.1.28) can probably substitute for MalK; Webb et al., 2008) from Streptococcus mutans (see paper)
    27% identity, 96% coverage of query (73.6 bits)

TC 3.A.1.1.10 / Q9KWT7 AlgM2, component of Alginate (MW 27,000 Da) (and Alginate oligosaccharides) uptake porter. Sphingomonas species A1 is a 'pit-forming' bacterium that directly incorporates alginate into its cytoplasm through a pit-dependent transport system, termed a 'superchannel' (Murata et al., 2008). The pit is a novel organ acquired through the fluidity and reconstitution of cell surface molecules, and through cooperation with the transport machinery in the cells. It confers upon bacterial cells a more efficient way to secure and assimilate macromolecules from Sphingomonas sp (see paper)
    25% identity, 78% coverage of query (72.0 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory