Searching for up to 100 curated homologs for AZOBR_RS01310 FitnessBrowser__azobra:AZOBR_RS01310 (313 a.a.)
Found high-coverage hits (≥70%) to 100 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
LDH_THET8 / Q5SJA1 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see 2 papers)
2e37C / Q5SJA1 Structure of tt0471 protein from thermus thermophilus
65% identity, 97% coverage of query (379 bits)
LDH_THECA / P06150 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Thermus caldophilus (see 3 papers)
65% identity, 97% coverage of query (377 bits)
3vphA L-lactate dehydrogenase from thermus caldophilus gk24 complexed with oxamate, nadh and fbp
65% identity, 97% coverage of query (377 bits)
3zznA 5-mutant (r79w, r151a, e279a, e299a,e313a) lactate-dehydrogenase from thermus thermophillus
65% identity, 97% coverage of query (375 bits)
2xxbA Penta-mutant of thermus thermophilus lactate dehydrogenase, complex with amp
65% identity, 97% coverage of query (375 bits)
LDH_THEAQ / P13715 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Thermus aquaticus (see paper)
62% identity, 98% coverage of query (374 bits)
LDH_DEIRA / P50933 L-lactate dehydrogenase; L-LDH; 2-ketoacid:NAD-dependent dehydrogenase; EC 1.1.1.27 from Deinococcus radiodurans (strain ATCC 13939 / DSM 20539 / JCM 16871 / CCUG 27074 / LMG 4051 / NBRC 15346 / NCIMB 9279 / VKM B-1422 / R1) (see paper)
51% identity, 96% coverage of query (270 bits)
B1A4R6 L-lactate dehydrogenase (EC 1.1.1.27) from Thermoanaerobacter ethanolicus (see paper)
41% identity, 98% coverage of query (266 bits)
1a5zA / P16115 Lactate dehydrogenase from thermotoga maritima (tmldh) (see paper)
45% identity, 98% coverage of query (263 bits)
LDH_THEMA / P16115 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see 2 papers)
45% identity, 98% coverage of query (263 bits)
P00345 L-lactate dehydrogenase (EC 1.1.1.27) from Priestia megaterium (see paper)
43% identity, 97% coverage of query (258 bits)
4ln1B / Q81EP4 Crystal structure of l-lactate dehydrogenase from bacillus cereus atcc 14579 complexed with calcium, nysgrc target 029452
43% identity, 98% coverage of query (258 bits)
E7CXT1 L-lactate dehydrogenase (EC 1.1.1.27) from Thermoanaerobacterium saccharolyticum (see paper)
40% identity, 98% coverage of query (256 bits)
B9MKZ8 L-lactate dehydrogenase (EC 1.1.1.27) from Caldicellulosiruptor bescii (see paper)
40% identity, 98% coverage of query (249 bits)
LDH_BACSU / P13714 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Bacillus subtilis (strain 168) (see paper)
41% identity, 96% coverage of query (247 bits)
1ldnA / P00344 Structure of a ternary complex of an allosteric lactate dehydrogenase from bacillus stearothermophilus at 2.5 angstroms resolution (see paper)
43% identity, 96% coverage of query (246 bits)
LDH_GEOSE / P00344 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Geobacillus stearothermophilus (Bacillus stearothermophilus) (see 3 papers)
43% identity, 96% coverage of query (246 bits)
3pqdB / P13714 Crystal structure of l-lactate dehydrogenase from bacillus subtilis complexed with fbp and NAD+
41% identity, 96% coverage of query (246 bits)
8ab3A / K9Z684 Crystal structure of the lactate dehydrogenase of cyanobacterium aponinum in complex with oxamate, nadh and fbp. (see paper)
41% identity, 97% coverage of query (241 bits)
W8CXQ9 L-lactate dehydrogenase (EC 1.1.1.27) from Weizmannia coagulans (see paper)
40% identity, 98% coverage of query (238 bits)
LDH1_STAAE / A6QDL6 L-lactate dehydrogenase 1; L-LDH 1; EC 1.1.1.27 from Staphylococcus aureus (strain Newman) (see paper)
LDH1_STAAC / Q5HJD7 L-lactate dehydrogenase 1; L-LDH 1; EC 1.1.1.27 from Staphylococcus aureus (strain COL) (see paper)
41% identity, 99% coverage of query (230 bits)
3h3jB / Q5HJD7 Crystal structure of lactate dehydrogenase mutant (a85r) from staphylococcus aureus complexed with NAD and pyruvate
40% identity, 99% coverage of query (228 bits)
3wswA / V5XPB8 Crystal structure of minor l-lactate dehydrogenase from enterococcus mundtii in the ligands-bound form (see paper)
41% identity, 98% coverage of query (227 bits)
Q8CMZ0 L-lactate dehydrogenase (EC 1.1.1.27) from Staphylococcus epidermidis (see paper)
39% identity, 98% coverage of query (227 bits)
A0A2U9AUU1 L-lactate dehydrogenase (EC 1.1.1.27) from Lacticaseibacillus casei (see paper)
39% identity, 98% coverage of query (226 bits)
ldh / AAA99896.1 L-lactate:NAD+ oxidoreductase from Lactococcus lactis (see 2 papers)
ldh / AAA25172.1 lactate dehydrogenase from Lactococcus lactis (see paper)
40% identity, 96% coverage of query (225 bits)
6j9tB Complex structure of lactobacillus casei lactate dehydrogenase with fructose-1,6-bisphosphate
39% identity, 98% coverage of query (225 bits)
ldh / P00343 L-lactate dehydrogenase subunit (EC 1.1.1.27) from Lactobacillus casei (see 2 papers)
LDH_LACCA / P00343 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Lacticaseibacillus casei (Lactobacillus casei) (see 3 papers)
39% identity, 98% coverage of query (224 bits)
ldhA L-lactate dehydrogenase 1; EC 1.1.1.27 from Lactococcus lactis subsp. lactis (see paper)
40% identity, 96% coverage of query (224 bits)
1llcA / P00343 Structure determination of the allosteric l-lactate dehydrogenase from lactobacillus casei at 3.0 angstroms resolution
39% identity, 98% coverage of query (223 bits)
LDH_LACLN / D8KFT1 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Lactococcus lactis subsp. cremoris (strain NZ9000) (see paper)
37% identity, 98% coverage of query (223 bits)
ldh / P26283 L-lactate dehydrogenase subunit (EC 1.1.1.27) from Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (see 4 papers)
P26283 L-lactate dehydrogenase (EC 1.1.1.27) from Streptococcus mutans serotype c (see paper)
40% identity, 96% coverage of query (222 bits)
3pqdD Crystal structure of l-lactate dehydrogenase from bacillus subtilis complexed with fbp and NAD+
38% identity, 96% coverage of query (222 bits)
LDH_STRPN / P0A3M9 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Streptococcus pneumoniae serotype 4 (strain ATCC BAA-334 / TIGR4) (see paper)
LDH_STRP2 / Q04K99 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Streptococcus pneumoniae serotype 2 (strain D39 / NCTC 7466) (see paper)
41% identity, 99% coverage of query (221 bits)
ldh2 / E8ME30 L-lactate dehydrogenase subunit (EC 1.1.1.27) from Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) (see 2 papers)
LDH2_BIFL2 / E8ME30 L-lactate dehydrogenase 2; L-LDH 2; FBP-dependent LDH; EC 1.1.1.27 from Bifidobacterium longum subsp. longum (strain ATCC 15707 / DSM 20219 / JCM 1217 / NCTC 11818 / E194b) (see 2 papers)
39% identity, 96% coverage of query (221 bits)
1lldA / E8ME30 Molecular basis of allosteric activation of bacterial l-lactate dehydrogenase (see paper)
39% identity, 96% coverage of query (221 bits)
1lthR T and r states in the crystals of bacterial l-lactate dehydrogenase reveal the mechanism for allosteric control
39% identity, 96% coverage of query (221 bits)
7epmA / P07864 Human ldhc complexed with NAD+ and ethylamino acetic acid (see paper)
39% identity, 96% coverage of query (218 bits)
ldh1 L-lactate dehydrogenase 1; EC 1.1.1.27 from Lactobacillus plantarum (see paper)
39% identity, 98% coverage of query (218 bits)
6h9sB / A9BGZ9 Crystal dimeric structure of petrotoga mobilis lactate dehydrogenase with nadh
37% identity, 100% coverage of query (217 bits)
LDH_LACPE / P56511 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Lactiplantibacillus pentosus (Lactobacillus pentosus) (see 2 papers)
ldh L-lactate dehydrogenase; EC 1.1.1.27 from Lactobacillus pentosus (see paper)
39% identity, 98% coverage of query (216 bits)
1ez4B / P56511 Crystal structure of non-allosteric l-lactate dehydrogenase from lactobacillus pentosus at 2.3 angstrom resolution (see paper)
39% identity, 98% coverage of query (216 bits)
LDH_PEDAC / Q59645 L-lactate dehydrogenase; L-LDH; EC 1.1.1.27 from Pediococcus acidilactici (see paper)
39% identity, 98% coverage of query (216 bits)
2ldbA Structure determination and refinement of bacillus stearothermophilus lactate dehydrogenase
40% identity, 96% coverage of query (216 bits)
LDH6A_HUMAN / Q6ZMR3 L-lactate dehydrogenase A-like 6A; LDHA-like protein 6A; EC 1.1.1.27 from Homo sapiens (Human) (see paper)
35% identity, 96% coverage of query (215 bits)
P07864 L-lactate dehydrogenase (EC 1.1.1.27) from Homo sapiens (see paper)
39% identity, 96% coverage of query (215 bits)
LDHA_PIG / P00339 L-lactate dehydrogenase A chain; LDH-A; LDH muscle subunit; LDH-M; EC 1.1.1.27 from Sus scrofa (Pig) (see paper)
P00339 L-lactate dehydrogenase (EC 1.1.1.27) from Sus scrofa (see paper)
38% identity, 96% coverage of query (215 bits)
A0A1A6GB48 L-lactate dehydrogenase (EC 1.1.1.27) from Enterococcus mundtii (see paper)
39% identity, 99% coverage of query (215 bits)
LDHA_HUMAN / P00338 L-lactate dehydrogenase A chain; LDH-A; Cell proliferation-inducing gene 19 protein; LDH muscle subunit; LDH-M; Renal carcinoma antigen NY-REN-59; EC 1.1.1.27 from Homo sapiens (Human) (see 5 papers)
P00338 L-lactate dehydrogenase (EC 1.1.1.27) from Homo sapiens (see 3 papers)
38% identity, 96% coverage of query (213 bits)
4qsmA / P00338 Crystal structure of human muscle l-lactate dehydrogenase in complex with inhibitor 2, 3-{[7-(2,4-dimethoxypyrimidin-5-yl)-3- sulfamoylquinolin-4-yl]amino}benzoic acid (see paper)
38% identity, 96% coverage of query (213 bits)
B7XH73 L-lactate dehydrogenase (EC 1.1.1.27) from Equus caballus (see paper)
38% identity, 96% coverage of query (213 bits)
7m2nA Crystal structure of human lactate dehydrogenase a with inhibitor compound 15
38% identity, 96% coverage of query (213 bits)
6bb2D Lactate dehydrogenase in complex with inhibitor (s)-5-((2- chlorophenyl)thio)-6'-(4-fluorophenoxy)-4-hydroxy-2-(thiophen-3-yl)- 2,3-dihydro-[2,2'-bipyridin]-6(1h)-one
38% identity, 96% coverage of query (213 bits)
6sbuA X-ray structure of human ldha with an allosteric inhibitor (compound 3)
38% identity, 96% coverage of query (213 bits)
6sbvA X-ray structure of human ldh-a with an allosteric inhibitor (compound 7)
38% identity, 96% coverage of query (213 bits)
5w8jA Crystal structure of lactate dehydrogenase a in complex with inhibitor compound 29
38% identity, 96% coverage of query (213 bits)
5w8iA Crystal structure of lactate dehydrogenase a in complex with inhibitor compound 23 and zinc
38% identity, 96% coverage of query (213 bits)
8fw6A Human lactate dehydrogenase a in complex with inhibitor chk-336
38% identity, 96% coverage of query (213 bits)
6q13A Crystal structure of ldha in complex with compound ncgc00420737-09 at 2.00 a resolution
38% identity, 96% coverage of query (213 bits)
6q0dA Crystal structure of ldha in complex with compound ncgc00384414-01 at 2.05 a resolution
38% identity, 96% coverage of query (213 bits)
6bb3A Lactate dehydrogenase in complex with inhibitor 3-((2-chlorophenyl) thio)-6-(6-((4-fluorophenyl)amino)pyridin-2-yl)-4-hydroxy-6- (thiophen-3-yl)-5,6-dihydro-2h-pyran-2-one
38% identity, 96% coverage of query (213 bits)
6badA Lactate dehydrogenase in complex with inhibitor (r)-3-((2- chlorophenyl)thio)-6-(3-((4-fluorophenyl)amino)phenyl)-4-hydroxy-6- (thiophen-3-yl)-5,6-dihydro-2h-pyran-2-one
38% identity, 96% coverage of query (213 bits)
5zjfA Ldha-ma
38% identity, 96% coverage of query (213 bits)
5w8lA Crystal structure of lactate dehydrogenase a in complex with inhibitor compound 59 and nadh
38% identity, 96% coverage of query (213 bits)
5w8hA Crystal structure of lactate dehydrogenase a in complex with inhibitor compound 11
38% identity, 96% coverage of query (213 bits)
5ixyA Lactate dehydrogenase in complex with hydroxylactam inhibitor compound 31: (2~{s})-5-(2-chlorophenyl)sulfanyl-2-(4-morpholin-4-ylphenyl)-4- oxidanyl-2-thiophen-3-yl-1,3-dihydropyridin-6-one
38% identity, 96% coverage of query (213 bits)
4zvvA Lactate dehydrogenase a in complex with a trisubstituted piperidine-2, 4-dione inhibitor gne-140
38% identity, 96% coverage of query (213 bits)
4r68A Lactate dehydrogenase in complex with inhibitor compound 31
38% identity, 96% coverage of query (213 bits)
4qo8A Lactate dehydrogenase a in complex with substituted 3-hydroxy-2- mercaptocyclohex-2-enone compound 104
38% identity, 96% coverage of query (213 bits)
4qo7A Lactate dehydrogenase a in complex with substituted 3-hydroxy-2- mercaptocyclohex-2-enone compound 7
38% identity, 96% coverage of query (213 bits)
4oknB Crystal structure of human muscle l-lactate dehydrogenase, ternary complex with nadh and oxalate
38% identity, 96% coverage of query (213 bits)
4oknA Crystal structure of human muscle l-lactate dehydrogenase, ternary complex with nadh and oxalate
38% identity, 96% coverage of query (213 bits)
4m49A Lactate dehydrogenase a in complex with a substituted pyrazine inhibitor compound 18
38% identity, 96% coverage of query (213 bits)
1i10A Human muscle l-lactate dehydrogenase m chain, ternary complex with nadh and oxamate
38% identity, 96% coverage of query (213 bits)
4qt0A Crystal structure of human muscle l-lactate dehydrogenase in complex with inhibitor 1, 3-{[3-carbamoyl-7-(2,4-dimethoxypyrimidin-5-yl) quinolin-4-yl]amino}benzoic acid
38% identity, 96% coverage of query (213 bits)
1ldbA / P00344 Structure determination and refinement of bacillus stearothermophilus lactate dehydrogenase (see paper)
40% identity, 96% coverage of query (211 bits)
LDHA_RABIT / P13491 L-lactate dehydrogenase A chain; LDH-A; LDH muscle subunit; LDH-M; EC 1.1.1.27 from Oryctolagus cuniculus (Rabbit) (see paper)
P13491 L-lactate dehydrogenase (EC 1.1.1.27) from Oryctolagus cuniculus (see 2 papers)
38% identity, 96% coverage of query (210 bits)
5kkcA L-lactate dehydrogenase from rabbit muscle with the inhibitor 6dhnad
38% identity, 96% coverage of query (210 bits)
5nqqC Rabbit muscle l-lactate dehydrogenase in complex with nadh and oxaloacetate
38% identity, 96% coverage of query (210 bits)
Ldha / P04642 lactate dehydrogenase subunit (EC 1.1.1.27) from Rattus norvegicus (see 3 papers)
37% identity, 96% coverage of query (209 bits)
Q0GND8 L-lactate dehydrogenase (EC 1.1.1.27) from Iguana iguana (see paper)
38% identity, 96% coverage of query (209 bits)
4ajlA Rat ldha in complex with 3-(ethylcarbamoylamino)-n-(2-methyl-1,3- benzothiazol-6-yl)propanamide
37% identity, 96% coverage of query (209 bits)
P04642 L-lactate dehydrogenase A chain; LDH-A; LDH muscle subunit; LDH-M; EC 1.1.1.27 from Rattus norvegicus (Rat)
37% identity, 96% coverage of query (209 bits)
4ajnA Rat ldha in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)-3-oxo-propyl)carbamoylamino)ethyl)phenyl)methyl) propanedioic acid
37% identity, 96% coverage of query (209 bits)
4al4A Rat ldha in complex with 2-((4-(2-((3-((2-methyl-1,3-benzothiazol-6- yl)amino)3-oxo-propyl)carbamoylamino)ethoxy) phenyl) methylpropanedioic acid
37% identity, 96% coverage of query (209 bits)
4ajoA Rat ldha in complex with 2-((4-(4-((3-((2-methyl-1,3-benzothiazol-6yl) amino)-3-oxo-propyl)amino)-4-oxo-butyl)phenyl)methyl)propanedioic acid
37% identity, 96% coverage of query (209 bits)
4aj4A Rat ldha in complex with 4-((2-allylsulfanyl-1,3-benzothizol-6-yl) amino)-4-oxo-butanoic acid
37% identity, 96% coverage of query (209 bits)
6p6uC Crystal structure of monoclinic rabbit muscle lactate dehydrogenase with four tetramers as the asymmetric unit
38% identity, 96% coverage of query (209 bits)
4ajiA Rat ldha in complex with 2-((3,4-dimethoxyphenyl)methyl))propanedioic acid
37% identity, 96% coverage of query (209 bits)
4ajhA Rat ldha in complex with n-(2-methyl-1,3-benzothiazol-6-yl)-3-ureido- propanamide and 2-(4-bromophenoxy)propanedioic acid
37% identity, 96% coverage of query (209 bits)
4ajeA Rat ldha in complex with 2-(4-bromophenoxy)propanedioic acid
37% identity, 96% coverage of query (209 bits)
4aj2A Rat ldha in complex with 5-(2-chlorophenyl)-1h-tetrazole
37% identity, 96% coverage of query (209 bits)
4aj1A Rat ldha in complex with n-(2-(methylamino)-1,3-benzothiazol-6-yl) acetamide
37% identity, 96% coverage of query (209 bits)
LDHA_SQUAC / P00341 L-lactate dehydrogenase A chain; LDH-A; LDH-M; EC 1.1.1.27 from Squalus acanthias (Spiny dogfish) (see paper)
38% identity, 96% coverage of query (208 bits)
Q0GND9 L-lactate dehydrogenase (EC 1.1.1.27) from Amblyrhynchus cristatus (see paper)
38% identity, 96% coverage of query (208 bits)
LDHA_MOUSE / P06151 L-lactate dehydrogenase A chain; LDH-A; LDH muscle subunit; LDH-M; EC 1.1.1.27 from Mus musculus (Mouse) (see paper)
37% identity, 96% coverage of query (206 bits)
LDH2_STAAE / A6QK89 L-lactate dehydrogenase 2; L-LDH 2; EC 1.1.1.27 from Staphylococcus aureus (strain Newman) (see paper)
LDH2_STAAC / Q5HCV0 L-lactate dehydrogenase 2; L-LDH 2; EC 1.1.1.27 from Staphylococcus aureus (strain COL) (see paper)
39% identity, 99% coverage of query (206 bits)
6baxA Lactate dehydrogenase in complex with inhibitor 6-(3-aminophenyl)-3- ((2-chlorophenyl)thio)-4-hydroxy-6-(thiophen-3-yl)-5,6-dihydro-2h- pyran-2-one
38% identity, 96% coverage of query (206 bits)
6bagA Lactate dehydrogenase in complex with inhibitor (r)-5-((2- chlorophenyl)thio)-6'-((4-fluorophenyl)amino)-4-hydroxy-2-(thiophen- 3-yl)-2,3-dihydro-[2,2'-bipyridin]-6(1h)-one
38% identity, 96% coverage of query (206 bits)
LDHB_HUMAN / P07195 L-lactate dehydrogenase B chain; LDH-B; LDH heart subunit; LDH-H; Renal carcinoma antigen NY-REN-46; EC 1.1.1.27 from Homo sapiens (Human) (see 11 papers)
35% identity, 96% coverage of query (205 bits)
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