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Searching for up to 100 curated homologs for AZOBR_RS02325 FitnessBrowser__azobra:AZOBR_RS02325 (503 a.a.)

Found high-coverage hits (≥70%) to 67 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Dpp / b3544 dipeptide ABC transporter periplasmic binding protein (EC 7.4.2.9) from Escherichia coli K-12 substr. MG1655 (see 18 papers)
dppA / P23847 dipeptide ABC transporter periplasmic binding protein (EC 7.4.2.9) from Escherichia coli (strain K12) (see 19 papers)
DPPA_ECOLI / P23847 Dipeptide-binding protein; DBP; Periplasmic dipeptide transport protein from Escherichia coli (strain K12) (see 8 papers)
dppA / GB|AAC76569.1 dipeptide ABC transporter, periplasmic dipeptide-binding protein DppA from Escherichia coli K12 (see 11 papers)
    32% identity, 78% coverage of query (196 bits)

1dppA / P23847 Dipeptide binding protein complex with glycyl-l-leucine (see paper)
    32% identity, 72% coverage of query (189 bits)

TC 3.A.1.5.39 / W0WL02 Periplasmic dipeptide transport protein, component of Di- and tri-peptide transporter, DppBCDF with periplasmic substrate binding receptors, A1, A3, A5, A7 and A9, each with differing specificities for peptides from Pseudomonas aeruginosa MH38
    32% identity, 83% coverage of query (182 bits)

DPPA4_PSEAB / A0A0H2ZGV7 Di/tripeptide-binding protein 4 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
    32% identity, 83% coverage of query (182 bits)

6hlxA / O50260 Structure of the pbp agaa in complex with agropinic acid from a.Tumefacien r10 (see paper)
    35% identity, 74% coverage of query (178 bits)

6ofqA / A0A1U9ISL1 Abc transporter-associated periplasmic binding protein dppa from helicobacter pylori in complex with peptide stsa (see paper)
    30% identity, 80% coverage of query (175 bits)

5f1qA / A0A0H2YM47 Crystal structure of periplasmic dipeptide transport protein from yersinia pestis
    30% identity, 77% coverage of query (173 bits)

3m8uA / B8F653 Crystal structure of glutathione-binding protein a (gbpa) from haemophilus parasuis sh0165 in complex with glutathione disulfide (gssg) (see paper)
    31% identity, 77% coverage of query (172 bits)

6tfxB / O50271 Structure in p21 form of the pbp/sbp moaa in complex with mannopinic acid from a.Tumefacien r10 (see paper)
    30% identity, 86% coverage of query (166 bits)

Build an alignment

Build an alignment for AZOBR_RS02325 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

GsiB / b0830 glutathione ABC transporter periplasmic binding protein (EC 7.4.2.10) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
gsiB / P75797 glutathione ABC transporter periplasmic binding protein (EC 7.4.2.10) from Escherichia coli (strain K12) (see 2 papers)
GSIB_ECOLI / P75797 Glutathione-binding protein GsiB from Escherichia coli (strain K12) (see 2 papers)
P75797 ABC-type glutathione transporter (EC 7.4.2.10) from Escherichia coli (see paper)
TC 3.A.1.5.11 / P75797 Putative binding protein yliB, component of Glutathione porter, YliABCD or GsiABCD from Escherichia coli (see 6 papers)
    29% identity, 94% coverage of query (166 bits)

6tfsA Structure in p3212 form of the pbp/sbp moaa in complex with glucopinic acid from a.Tumefacien r10
    30% identity, 86% coverage of query (166 bits)

6tfqA Structure in p3212 form of the pbp/sbp moaa in complex with mannopinic acid from a.Tumefacien r10
    30% identity, 86% coverage of query (166 bits)

TRPBP_PSEAE / Q9HVS4 Tripeptide-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    30% identity, 93% coverage of query (163 bits)

TC 3.A.1.5.39 / W0WLZ1 Periplasmic dipeptide transport protein, component of Di- and tri-peptide transporter, DppBCDF with periplasmic substrate binding receptors, A1, A3, A5, A7 and A9, each with differing specificities for peptides from Pseudomonas aeruginosa MH38
    30% identity, 91% coverage of query (163 bits)

TC 3.A.1.5.39 / W0WKZ8 Periplasmic dipeptide transport protein, component of Di- and tri-peptide transporter, DppBCDF with periplasmic substrate binding receptors, A1, A3, A5, A7 and A9, each with differing specificities for peptides from Pseudomonas aeruginosa MH38
    30% identity, 93% coverage of query (162 bits)

1uqwA / P75797 Crystal structure of ylib protein from escherichia coi
    29% identity, 90% coverage of query (161 bits)

DPPA1_PSEAB / A0A0H2ZGV2 Di/tripeptide-binding protein 1 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
    30% identity, 91% coverage of query (161 bits)

DPPA3_PSEAB / A0A0H2ZGN2 Di/tripeptide-binding protein 3 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
    30% identity, 89% coverage of query (161 bits)

DPPA2_PSEAB / A0A0H2ZGW2 Di/tripeptide-binding protein 2 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
    30% identity, 93% coverage of query (161 bits)

TC 3.A.1.5.39 / W0WJ85 Periplasmic dipeptide transport protein, component of Di- and tri-peptide transporter, DppBCDF with periplasmic substrate binding receptors, A1, A3, A5, A7 and A9, each with differing specificities for peptides from Pseudomonas aeruginosa MH38
    30% identity, 89% coverage of query (160 bits)

DIPBP_PSEAE / Q9HVS1 Dipeptide-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
    30% identity, 89% coverage of query (160 bits)

7kz9A Crystal structure of pseudomonas sp. Pdc86 substrate-binding protein aapf in complex with a signaling molecule heheaa (see paper)
    29% identity, 90% coverage of query (157 bits)

DdpA / b1487 putative D,D-dipeptide ABC transporter periplasmic binding protein from Escherichia coli K-12 substr. MG1655 (see 4 papers)
DDPA_ECOLI / P76128 Probable D,D-dipeptide-binding periplasmic protein DdpA from Escherichia coli (strain K12) (see paper)
ddpA / RF|NP_416004.1 dipeptide ABC transporter, permease protein DdpA from Escherichia coli K12 (see paper)
    30% identity, 92% coverage of query (155 bits)

DPPA5_PSEAB / A0A0H2ZI72 Probable di/tripeptide-binding protein 5 from Pseudomonas aeruginosa (strain UCBPP-PA14) (see paper)
    29% identity, 84% coverage of query (145 bits)

TC 3.A.1.5.20 / P42061 AppA, component of 5-6 amino acyl oligopeptide transporter AppA-F from Bacillus subtilis (see 2 papers)
    28% identity, 86% coverage of query (145 bits)

appA / GB|CAB12995.1 oligopeptide ABC transporter, oligopeptide-binding protein AppA from Bacillus subtilis (see 2 papers)
    27% identity, 86% coverage of query (142 bits)

1xocA / P42061 The structure of the oligopeptide-binding protein, appa, from bacillus subtilis in complex with a nonapeptide. (see paper)
    29% identity, 72% coverage of query (142 bits)

TC 3.A.1.5.39 / W0WQF0 Periplasmic dipeptide transport protein, component of Di- and tri-peptide transporter, DppBCDF with periplasmic substrate binding receptors, A1, A3, A5, A7 and A9, each with differing specificities for peptides from Pseudomonas aeruginosa MH38
    29% identity, 86% coverage of query (141 bits)

4qflA / A7Y7W1 Crystal structure of dipeptide binding protein from pseudoalteromonas sp. Sm9913 in complex with ala-phe (see paper)
    28% identity, 72% coverage of query (140 bits)

4qfpA Crystal structure of dipeptide binding protein from pseudoalteromonas sp. Sm9913 in complex with val-thr
    28% identity, 72% coverage of query (140 bits)

4qfoA Crystal structure of dipeptide binding protein from pseudoalteromonas sp. Sm9913 in complex with met-leu
    28% identity, 72% coverage of query (140 bits)

4qfnA Crystal structure of dipeptide binding protein from pseudoalteromonas sp. Sm9913 in complex with gly-glu
    28% identity, 72% coverage of query (140 bits)

OppA / b1243 oligopeptide ABC transporter periplasmic binding protein (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 19 papers)
oppA / P23843 oligopeptide ABC transporter periplasmic binding protein (EC 7.4.2.6) from Escherichia coli (strain K12) (see 20 papers)
TC 3.A.1.5.41 / P23843 Periplasmic oligopeptide-binding protein, component of Oligopeptide transporter, OppABCDF/MppA/YgiS from Escherichia coli (strain K12)
oppA / GB|BAA14775.2 periplasmic oligopeptide-binding protein from Escherichia coli K12 (see 7 papers)
    28% identity, 96% coverage of query (135 bits)

TC 3.A.1.5.1 / P06202 OppA aka STM1746, component of Oligopeptide porter (also takes up amino glycoside antibiotics such as kanamycin, streptomycin and neomycin as well as cell wall-derived peptides such as murein tripeptide). It transports substrate peptides of 2-5 amino acids with highest affinity for tripeptides. Also transports δ-aminolevulinic acid (ALA). [May be regulated by PTS Enzyme INtr-aspartokinase.] ATP-binding to OppDF may result in donation of peptide to OppBC and simultaneous release of OppA from Salmonella typhimurium (see 7 papers)
    27% identity, 91% coverage of query (135 bits)

1b05A / P06202 Structure of oligo-peptide binding protein complexed with lys-cys-lys (see paper)
    27% identity, 91% coverage of query (135 bits)

2rkmA Structure of oppa complexed with lys-lys
    27% identity, 91% coverage of query (135 bits)

1olcA Oligo-peptide binding protein (oppa) complexed with lys-lys- lys-ala
    27% identity, 91% coverage of query (135 bits)

Q5V9S2 ABC-type oligopeptide transporter (EC 7.4.2.6) from Vibrio fluvialis (see paper)
TC 3.A.1.5.22 / Q5V9S2 OppA, component of The peptide transporter OppA,B,C,D,F (influences biofilm formation; Lee et al., 2004). Similar to 3.A.1.5.1, OppA is similar to the Vibrio furnissii OppA that provides several functions: hemolysis, antibiotic resistance, and virulence from Vibrio fluvialis (see paper)
    27% identity, 91% coverage of query (134 bits)

Q0PRU9 ABC-type oligopeptide transporter (EC 7.4.2.6) from Vibrio furnissii (see paper)
    26% identity, 91% coverage of query (130 bits)

3tcfA / P23843 Crystal structure of e. Coli oppa complexed with endogenous ligands (see paper)
    28% identity, 83% coverage of query (130 bits)

TC 3.A.1.5.18 / O50927 OppA5, component of The oligopeptide transporter OppA1-5, B1, C1, DF (functions with five binding proteins of differing induction properties and peptide specificities; OppA1-3 are chromosomally encoded; OppA4 and 5 are plasmid encoded.) from Borrelia burgdorferi (Lyme disease spirochete) (see paper)
    30% identity, 78% coverage of query (127 bits)

YnaH / b1329 murein tripeptide ABC transporter periplasmic binding protein (EC 7.4.2.6) from Escherichia coli K-12 substr. MG1655 (see 10 papers)
mppA / P77348 murein tripeptide ABC transporter periplasmic binding protein (EC 7.4.2.6) from Escherichia coli (strain K12) (see 9 papers)
TC 3.A.1.5.1 / TC 3.A.1.5.41 / P77348 MppA aka B1329, component of Oligopeptide transporter, OppABCDF/MppA/YgiS from Escherichia coli (see 4 papers)
    26% identity, 96% coverage of query (127 bits)

2z23A / A0A0H2W5P5 Crystal structure of y.Pestis oligo peptide binding protein oppa with tri-lysine ligand (see paper)
    27% identity, 91% coverage of query (122 bits)

3o9pA / P77348 The structure of the escherichia coli murein tripeptide binding protein mppa (see paper)
    26% identity, 91% coverage of query (122 bits)

4gl8A / H7C7K8 X-ray crystal structure of a periplasmic oligopeptide-binding protein/oligopeptide abc transporter(oppaiv) from borrelia burgdorferi
    28% identity, 76% coverage of query (120 bits)

OPPA_BACSU / P24141 Oligopeptide-binding protein OppA; Stage 0 sporulation protein KA from Bacillus subtilis (strain 168) (see 5 papers)
    26% identity, 81% coverage of query (120 bits)

6dtgA / Q4QLH0 Crystal structure of haemophilus influenzae oppa complex with ylgangrgggs (see paper)
    26% identity, 76% coverage of query (118 bits)

8arnA / P24141 Crystal structure of the peptide binding protein, oppa, from bacillus subtilis in complex with an endogenous tetrapeptide (see paper)
    27% identity, 74% coverage of query (118 bits)

8cayA Pbp acca from a. Tumefaciens bo542 in complex with agrocinopine d-like
    29% identity, 71% coverage of query (110 bits)

8cawA / A0A2P0QK24 Pbp acca from a. Tumefaciens bo542 in complex with agrocin84 (see paper)
    29% identity, 71% coverage of query (110 bits)

8cb9A Pbp acca from a. Tumefaciens bo542 in complex with d-glucose-2- phosphate
    29% identity, 71% coverage of query (109 bits)

8cdoA Pbp acca-f144yg440q from a. Tumefaciens bo542 in complex with agrocinopinE C-like
    29% identity, 71% coverage of query (104 bits)

8ay0B / P26906 Crystal structure of the peptide binding protein dppe from bacillus subtilis in complex with murein tripeptide (see paper)
    26% identity, 71% coverage of query (102 bits)

7og0B / Q4QL73 Nontypeable haemophillus influenzae sapa in open and closed conformations, in complex with double stranded RNA (see paper)
    26% identity, 86% coverage of query (99.4 bits)

7ofwA Nontypeable haemophillus influenzae sapa in complex with heme
    26% identity, 86% coverage of query (98.2 bits)

4pfyA / Q9X0V0 Crystal structure of mannohexaose bound oligopeptide abc transporter, periplasmic oligopeptide-binding protein (tm1223) from thermotoga maritima at 1.5 a resolution (see paper)
    26% identity, 85% coverage of query (85.5 bits)

3zs6A / Q63ID0 The structural characterization of burkholderia pseudomallei oppa. (see paper)
    24% identity, 88% coverage of query (83.2 bits)

8i5jA Crystal structure of chitin oligosaccharide binding protein from vibrio cholera.
    24% identity, 79% coverage of query (80.9 bits)

4gfrA / Q9KUA3 Crystal structure of the liganded chitin oligasaccharide binding protein
    24% identity, 79% coverage of query (80.9 bits)

2wokA Clavulanic acid biosynthesis oligopeptide binding protein 2 complexed with bradykinin
    27% identity, 81% coverage of query (77.4 bits)

2wopA / Q8KRB4 Clavulanic acid biosynthesis oligopeptide binding protein 2 complexed with arginine (see paper)
    27% identity, 81% coverage of query (77.0 bits)

3rybA / A2RJ53 Lactococcal oppa complexed with slsqslsqs (see paper)
    24% identity, 84% coverage of query (75.9 bits)

4fajA / Q51643 Structure and mode of peptide binding of pheromone receptor prgz (see paper)
    23% identity, 71% coverage of query (74.7 bits)

7ebiA Chitin-specific solute binding protein from vibrio harveyi co- crystalized with chitotetraose. (see paper)
    23% identity, 79% coverage of query (72.4 bits)

5hm4B Crystal structure of oligopeptide abc transporter, periplasmic oligopeptide-binding protein (tm1226) from thermotoga maritima at 2.0 a resolution
    23% identity, 88% coverage of query (61.6 bits)

4pfwA Crystal structure of mannohexaose bound oligopeptide abc transporter, periplasmic oligopeptide-binding protein (tm1226) from thermotoga maritima at 2.2 a resolution
    23% identity, 88% coverage of query (61.6 bits)

4pfuB / G4FEC0 Crystal structure of mannobiose bound oligopeptide abc transporter, periplasmic oligopeptide-binding protein (tm1226) from thermotoga maritima at 2.05 a resolution (see paper)
    23% identity, 88% coverage of query (61.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory