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Searching for up to 100 curated homologs for AZOBR_RS05280 FitnessBrowser__azobra:AZOBR_RS05280 (232 a.a.)

Found high-coverage hits (≥70%) to 26 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

ald2 / Q2RXI1 5-(methylthio)ribulose-1-phosphate aldolase (EC 4.1.2.62) from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1) (see 2 papers)
ALD2_RHORT / Q2RXI1 5-methylthioribulose-1-phosphate/5-deoxyribulose-1-phosphate aldolase; EC 4.1.2.62 from Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1.1 / DSM 467 / LMG 4362 / NCIMB 8255 / S1) (see 2 papers)
    56% identity, 88% coverage of query (224 bits)

Prd / b2800 L-fuculose-phosphate aldolase (EC 4.1.2.17) from Escherichia coli K-12 substr. MG1655 (see 9 papers)
fucA / P0AB87 L-fuculose-phosphate aldolase (EC 4.1.2.17) from Escherichia coli (strain K12) (see 8 papers)
FUCA_ECOLI / P0AB87 L-fuculose phosphate aldolase; D-ribulose-phosphate aldolase; L-fuculose-1-phosphate aldolase; EC 4.1.2.17 from Escherichia coli (strain K12) (see 7 papers)
fucA / RF|NP_417280 L-fuculose-1-phosphate aldolase from Escherichia coli K12 (see 3 papers)
    48% identity, 90% coverage of query (196 bits)

BWI76_RS22915 L-fuculose phosphate aldolase (EC 4.1.2.17) from Klebsiella michiganensis M5al
    48% identity, 90% coverage of query (194 bits)

2fuaA / P0AB87 L-fuculose 1-phosphate aldolase crystal form t with cobalt (see paper)
    49% identity, 86% coverage of query (193 bits)

1dzuP L-fuculose-1-phosphate aldolase from escherichia coli mutant t26a
    49% identity, 86% coverage of query (193 bits)

4fuaA L-fuculose-1-phosphate aldolase complex with pgh
    49% identity, 85% coverage of query (192 bits)

7x78A L-fuculose 1-phosphate aldolase
    48% identity, 85% coverage of query (184 bits)

ald2 / J7RCN0 5-deoxyribulose 1-phosphate aldolase (EC 4.1.2.62) from Escherichia coli (see paper)
    44% identity, 88% coverage of query (166 bits)

ALD2_ECO45 / B7MMH7 5-methylthioribulose-1-phosphate/5-deoxyribulose-1-phosphate aldolase; EC 4.1.2.62 from Escherichia coli O45:K1 (strain S88 / ExPEC) (see paper)
    44% identity, 88% coverage of query (164 bits)

drdA / P0DTQ0 5-deoxy-D-ribulose 1-phosphate aldolase (EC 4.1.2.62) from Bacillus thuringiensis serovar kurstaki (strain ATCC 35866 / NRRL B-4488 / HD73) (see paper)
DRDA_BACT7 / P0DTQ0 5-deoxy-D-ribulose 1-phosphate aldolase; 5-deoxyribose disposal aldolase; EC 4.1.2.- from Bacillus thuringiensis serovar kurstaki (strain ATCC 35866 / NRRL B-4488 / HD73) (see paper)
P0DTQ0 5-deoxyribulose 1-phosphate aldolase (EC 4.1.2.62) from Bacillus thuringiensis serovar kurstaki (see paper)
    39% identity, 87% coverage of query (151 bits)

6btgA Crystal structure of deoxyribose-phosphate aldolase bound with dhap from bacillus thuringiensis (see paper)
    39% identity, 86% coverage of query (151 bits)

4c25A / A0A0H2US48 L-fuculose 1-phosphate aldolase (see paper)
    44% identity, 80% coverage of query (151 bits)

F8D9F5 D-ribulose 1-phosphate aldolase (EC 4.1.2.17) from Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) (see paper)
RU1PA_HALXS / F8D9F5 Ribulose-1-phosphate aldolase; Ru1P aldolase; EC 4.1.2.- from Halopiger xanaduensis (strain DSM 18323 / JCM 14033 / SH-6) (see paper)
    38% identity, 89% coverage of query (117 bits)

C4B4W3 L-ribulose-5-phosphate 4-epimerase (EC 5.1.3.4) from Corynebacterium glutamicum (see paper)
    32% identity, 80% coverage of query (88.6 bits)

BT1274 L-fuculose-1-phosphate aldolase FucA (4.1.2.17); D-ribulose-1-phosphate aldolase from Bacteroides thetaiotaomicron VPI-5482
    34% identity, 75% coverage of query (74.7 bits)

otnC / Q57199 3-dehydro-4-phosphotetronate decarboxylase (EC 4.1.1.104) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
OTNC_HAEIN / Q57199 3-oxo-tetronate 4-phosphate decarboxylase; EC 4.1.1.104 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
Q57199 3-dehydro-4-phosphotetronate decarboxylase (EC 4.1.1.104) from Haemophilus influenzae (see paper)
    31% identity, 80% coverage of query (69.3 bits)

OTNC_PECAS / Q6CZ24 3-oxo-tetronate 4-phosphate decarboxylase; EC 4.1.1.104 from Pectobacterium atrosepticum (strain SCRI 1043 / ATCC BAA-672) (Erwinia carotovora subsp. atroseptica) (see paper)
Q6CZ24 3-dehydro-4-phosphotetronate decarboxylase (EC 4.1.1.104) from Pectobacterium atrosepticum (see paper)
    31% identity, 78% coverage of query (67.0 bits)

Build an alignment

Build an alignment for AZOBR_RS05280 and 17 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

MJ1418 / Q58813 fuculose-1-phosphate aldolase subunit (EC 4.1.2.17) from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (see paper)
FUCA_METJA / Q58813 L-fuculose phosphate aldolase; L-fuculose-1-phosphate aldolase; EC 4.1.2.17 from Methanocaldococcus jannaschii (strain ATCC 43067 / DSM 2661 / JAL-1 / JCM 10045 / NBRC 100440) (Methanococcus jannaschii) (see 3 papers)
Q58813 L-fuculose-phosphate aldolase (EC 4.1.2.17) from Methanocaldococcus jannaschii (see paper)
    27% identity, 75% coverage of query (66.2 bits)

6voqA / Q0QC76 Crystal structure of ygbl, a putative aldolase/epimerase/decarboxylase from klebsiella pneumoniae
    29% identity, 75% coverage of query (63.5 bits)

ARAD_BACSU / P94525 L-ribulose-5-phosphate 4-epimerase; Phosphoribulose isomerase; EC 5.1.3.4 from Bacillus subtilis (strain 168) (see paper)
    28% identity, 80% coverage of query (61.2 bits)

4xxfA / A0A0J9X279 L-fuculose 1-phosphate aldolase from glaciozyma antarctica pi12 (see paper)
    28% identity, 74% coverage of query (58.5 bits)

novR / Q9L9F0 3-dimethylallyl-4-hydroxyphenylpyruvate oxygenase (EC 1.13.12.23; EC 1.13.11.83) from Streptomyces niveus (see paper)
    26% identity, 71% coverage of query (55.1 bits)

CLOR_STRRC / Q8GHB1 4-hydroxy-3-prenylphenylpyruvate oxygenase/4-hydroxy-3-prenylbenzoate synthase; Bifunctional non-heme iron oxygenase; Clorobiocin biosynthesis protein CloR; EC 1.13.11.83; EC 1.13.12.23 from Streptomyces roseochromogenus subsp. oscitans (see 2 papers)
Q8GHB1 4-hydroxy-3-prenylphenylpyruvate oxygenase (EC 1.13.11.83); 4-hydroxy-3-prenylbenzoate synthase (EC 1.13.12.23) from Streptomyces roseochromogenus (see 2 papers)
    27% identity, 71% coverage of query (55.1 bits)

Q9AGK2 3,4-dihydroxyphthalate decarboxylase (EC 4.1.1.69) from Arthrobacter keyseri (see paper)
    24% identity, 78% coverage of query (46.2 bits)

mlr6791 / Q988D0 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase monomer (EC 4.1.1.51) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (see paper)
HMPD_RHILO / Q988D0 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase; HMPDdc; EC 4.1.1.51 from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099)) (see paper)
    26% identity, 83% coverage of query (42.7 bits)

2z7bA / Q988D0 Crystal structure of mesorhizobium loti 3-hydroxy-2-methylpyridine-4, 5-dicarboxylate decarboxylase (see paper)
    26% identity, 83% coverage of query (42.7 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory