Sites on a Tree

 

Searching for up to 100 curated homologs for AZOBR_RS05475 FitnessBrowser__azobra:AZOBR_RS05475 (359 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

6fahE / H6LGM8 Molecular basis of the flavin-based electron-bifurcating caffeyl-coa reductase reaction (see paper)
    47% identity, 93% coverage of query (305 bits)

CARE_ACEWD / H6LGM8 Caffeyl-CoA reductase-Etf complex subunit CarE; Electron transfer flavoprotein large subunit; ETFLS; Electron transfer flavoprotein subunit alpha; Alpha-ETF; EC 1.3.1.108 from Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) (see paper)
H6LGM8 caffeoyl-CoA reductase (subunit 1/3) (EC 1.3.1.108) from Acetobacterium woodii (see paper)
    47% identity, 93% coverage of query (305 bits)

7koeB / R4P3F4 Electron bifurcating flavoprotein fix/etfabcx (see paper)
    50% identity, 91% coverage of query (277 bits)

Q18AQ5 butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin) (subunit 1/3) (EC 1.3.1.109) from Clostridioides difficile (see paper)
    42% identity, 94% coverage of query (266 bits)

5ol2A / A0A125V455 The electron transferring flavoprotein/butyryl-coa dehydrogenase complex from clostridium difficile (see paper)
    42% identity, 94% coverage of query (266 bits)

D2RIQ3 butanoyl-CoA dehydrogenase complex (NAD+, ferredoxin) (subunit 2/3) (EC 1.3.1.109); short-chain acyl-CoA dehydrogenase (EC 1.3.8.1) from Acidaminococcus fermentans (see paper)
    43% identity, 90% coverage of query (258 bits)

4kpuA / D2RIQ3 Electron transferring flavoprotein of acidaminococcus fermentans: towards a mechanism of flavin-based electron bifurcation (see paper)
    43% identity, 90% coverage of query (258 bits)

acrA / G3KIM6 electron-transferring flavoprotein α subunit from Anaerotignum propionicum (see paper)
ETFA_ANAPI / G3KIM6 Acryloyl-CoA reductase electron transfer subunit beta; Electron transfer flavoprotein large subunit; ETFLS; Electron transfer flavoprotein subunit beta; Beta-ETF from Anaerotignum propionicum (Clostridium propionicum) (see paper)
G3KIM6 acrylyl-CoA reductase (NADH) (EC 1.3.1.95) from Anaerotignum propionicum (see paper)
    41% identity, 92% coverage of query (253 bits)

7qh2A / H6LBB1 Cryo-em structure of ldh-etfab complex from acetobacterium woodii (see paper)
    39% identity, 90% coverage of query (235 bits)

LCTC_ACEWD / H6LBB1 Lactate dehydrogenase (NAD(+),ferredoxin) subunit LctC; Electron transfer flavoprotein large subunit; Electron transfer flavoprotein subunit alpha; EtfA; Lactate dehydrogenase-Etf complex subunit LctC; EC 1.1.1.436 from Acetobacterium woodii (strain ATCC 29683 / DSM 1030 / JCM 2381 / KCTC 1655 / WB1) (see paper)
H6LBB1 lactate dehydrogenase (NAD+, ferredoxin) (subunit 2/3) (EC 1.3.1.110) from Acetobacterium woodii (see paper)
    39% identity, 90% coverage of query (234 bits)

ETFA_SYNWW / Q0AZ33 Electron transfer flavoprotein subunit alpha from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) (see 2 papers)
    38% identity, 91% coverage of query (211 bits)

Build an alignment

Build an alignment for AZOBR_RS05475 and 11 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

ETFA_ARATH / Q9C6I6 Electron transfer flavoprotein subunit alpha, mitochondrial; Alpha-ETF from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    28% identity, 91% coverage of query (133 bits)

YaaR / b0042 putative electron transfer flavoprotein FixB from Escherichia coli K-12 substr. MG1655 (see 7 papers)
FIXB_ECOLI / P31574 Protein FixB from Escherichia coli (strain K12) (see paper)
    31% identity, 86% coverage of query (127 bits)

YdiR / b1698 putative electron transfer flavoprotein subunit YdiR from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    31% identity, 93% coverage of query (124 bits)

5ow0A / Q39VG4 Crystal structure of an electron transfer flavoprotein from geobacter metallireducens (see paper)
    28% identity, 87% coverage of query (113 bits)

ETFA_METME / P53571 Electron transfer flavoprotein subunit alpha; Alpha-ETF; Electron transfer flavoprotein large subunit; ETFLS from Methylophilus methylotrophus (Bacterium W3A1) (see 2 papers)
AAA64953.1 electron transfer flavoprotein large subunit from Methylophilus methylotrophus W3A1 (see paper)
    29% identity, 88% coverage of query (112 bits)

3clrD / P53571 Crystal structure of the r236a etf mutant from m. Methylotrophus (see paper)
    28% identity, 88% coverage of query (109 bits)

ETFA_CHRSD / Q1QYV9 Electron transfer flavoprotein subunit alpha; Alpha-ETF from Chromohalobacter salexigens (strain ATCC BAA-138 / DSM 3043 / CIP 106854 / NCIMB 13768 / 1H11) (see paper)
    29% identity, 85% coverage of query (90.5 bits)

YgcQ / b2769 putative flavoprotein from Escherichia coli K-12 substr. MG1655 (see paper)
    25% identity, 70% coverage of query (67.0 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory