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Searching for up to 100 curated homologs for AZOBR_RS05920 FitnessBrowser__azobra:AZOBR_RS05920 (259 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

pcaL / AAC38246.1 3-oxoadipate enol-lactone hydrolase/4-carboxymuconolactone decarboxylase from Rhodococcus opacus (see paper)
    44% identity, 88% coverage of query (179 bits)

Q0SH24 3-oxoadipate enol-lactonase (EC 3.1.1.24); 4-carboxymuconolactone decarboxylase (EC 4.1.1.44) from Rhodococcus jostii (see paper)
    44% identity, 88% coverage of query (176 bits)

pcaD / AAF34270.1 beta-ketoadipate enol-lactone hydrolase from Agrobacterium tumefaciens (see 2 papers)
    36% identity, 98% coverage of query (159 bits)

catD / AAC46435.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 8 papers)
    38% identity, 88% coverage of query (158 bits)

AO353_17230 Beta-ketoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas fluorescens FW300-N2E3
    34% identity, 100% coverage of query (155 bits)

Q13KT2 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Paraburkholderia xenovorans (see 2 papers)
    34% identity, 97% coverage of query (154 bits)

2xuaH / Q13KT2 Crystal structure of the enol-lactonase from burkholderia xenovorans lb400 (see paper)
    34% identity, 96% coverage of query (152 bits)

pcaD / Q88N36 subunit of 3-oxoadipate enol-lactone hydrolase (EC 3.1.1.24) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 5 papers)
Q88N36 3-oxoadipate enol-lactonase (EC 3.1.1.24) from Pseudomonas putida (see paper)
    35% identity, 96% coverage of query (144 bits)

catD / BAA75208.1 b-ketoadipate enol-lactone hydrolase from Frateuria sp. ANA-18 (see paper)
catD / BAC82535.1 b-ketoadipate enol-lactone hydrolase from Frateuria sp. ANA-18 (see 3 papers)
    36% identity, 95% coverage of query (138 bits)

Build an alignment

Build an alignment for AZOBR_RS05920 and 9 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

pcaD / AAC37150.1 beta-ketoadipate enol-lactone hydrolase from Acinetobacter baylyi (see 11 papers)
    26% identity, 99% coverage of query (133 bits)

4uhdA Structural studies of a thermophilic esterase from thermogutta terrifontis (acetate bound)
    33% identity, 95% coverage of query (114 bits)

4uhfA / A0A0M3KKY6 Structural studies of a thermophilic esterase from thermogutta terrifontis (l37a mutant with butyrate bound) (see paper)
    33% identity, 95% coverage of query (113 bits)

4uheA Structural studies of a thermophilic esterase from thermogutta terrifontis (malate bound)
    33% identity, 95% coverage of query (113 bits)

EstN1 / K0IAM1 pimeloyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85) from Nitrososphaera gargensis (strain Ga9.2) (see paper)
    30% identity, 93% coverage of query (108 bits)

bioH / BAB39459.1 BioH from Kurthia sp. 538-KA26 (see paper)
    30% identity, 98% coverage of query (104 bits)

6eb3B Structural and enzymatic characterization of an esterase from a metagenomic library
    31% identity, 97% coverage of query (93.2 bits)

6eb3C Structural and enzymatic characterization of an esterase from a metagenomic library
    31% identity, 97% coverage of query (92.8 bits)

6eb3A Structural and enzymatic characterization of an esterase from a metagenomic library
    30% identity, 97% coverage of query (92.0 bits)

TGND_ACIAD / Q6F9F4 (E)-2-((N-methylformamido)methylene)succinate hydrolase; MFMS hydrolase; EC 3.5.1.- from Acinetobacter baylyi (strain ATCC 33305 / BD413 / ADP1) (see paper)
    27% identity, 95% coverage of query (85.9 bits)

flnE / BAC75995.1 meta cleavage compound hydrolase from Terrabacter sp. DBF63 (see paper)
    28% identity, 92% coverage of query (84.3 bits)

G3KFX4 2-hydroxymuconate-6-semialdehyde hydrolase (EC 3.7.1.9) from Pseudomonas sp. (see paper)
    31% identity, 96% coverage of query (77.4 bits)

Q8KT44 carboxylesterase (EC 3.1.1.1) from Lacticaseibacillus casei (see paper)
    24% identity, 92% coverage of query (76.6 bits)

3hi4A Switching catalysis from hydrolysis to perhydrolysis in p. Fluorescens esterase
    28% identity, 96% coverage of query (74.7 bits)

3heaA The l29p/l124i mutation of pseudomonas fluorescens esterase
    28% identity, 96% coverage of query (74.7 bits)

ESTE_PSEFL / P22862 Arylesterase; Aryl-ester hydrolase; Carboxylic acid perhydrolase; PFE; Putative bromoperoxidase; EC 3.1.1.2; EC 1.-.-.- from Pseudomonas fluorescens (see 8 papers)
GI|951089 arylesterase; EC 1.-.-.-; EC 3.1.1.2 from Pseudomonas fluorescens (see 3 papers)
AAB60168.1 esterase from Pseudomonas fluorescens (see 2 papers)
    28% identity, 96% coverage of query (74.3 bits)

3ia2A Pseudomonas fluorescens esterase complexed to the r-enantiomer of a sulfonate transition state analog
    28% identity, 96% coverage of query (74.3 bits)

lnmJ / Q8GGP2 leinamycin polyketide synthase LnmJ from Streptomyces atroolivaceus (see 5 papers)
    29% identity, 91% coverage of query (71.6 bits)

aamsh1 / Q988D4 2-(acetamidomethylene)succinate hydrolase monomer (EC 3.5.1.29) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (see 7 papers)
AAMHY_RHILO / Q988D4 2-(acetamidomethylene)succinate hydrolase; alpha-(N-acetylaminomethylene)succinic acid amidohydrolase; AAMS amidohydrolase; EC 3.5.1.29 from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099)) (see 2 papers)
Q988D4 2-(acetamidomethylene)succinate hydrolase (EC 3.5.1.29) from Mesorhizobium loti (see 2 papers)
    30% identity, 95% coverage of query (71.2 bits)

8pi1B / P22862 Bicyclic incypro pseudomonas fluorescens esterase (see paper)
    28% identity, 97% coverage of query (71.2 bits)

cpoL / PDB|1A88_A non-heme chloroperoxidase; EC 1.11.1.10 from Streptomyces lividans (see 2 papers)
cpoL / AAA18642.1 chloroperoxidase from Streptomyces lividans (see paper)
    29% identity, 84% coverage of query (71.2 bits)

todF / P23133 2-hydroxy-6-oxohepta-2,4-dienoate hydrolase (EC 3.7.1.25) from Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) (see paper)
TODF_PSEP1 / P23133 2-hydroxy-6-oxo-2,4-heptadienoate hydrolase; HOHH; EC 3.7.1.25 from Pseudomonas putida (strain ATCC 700007 / DSM 6899 / BCRC 17059 / F1) (see 2 papers)
    28% identity, 92% coverage of query (68.6 bits)

O73957 carboxylesterase (EC 3.1.1.1) from Sulfolobus acidocaldarius (see paper)
    25% identity, 95% coverage of query (68.2 bits)

5h3hB / K0ACL0 Esterase (eaest) from exiguobacterium antarcticum (see paper)
    25% identity, 95% coverage of query (67.8 bits)

D0EPY0 carboxylesterase (EC 3.1.1.1) from Bacillus subtilis (see paper)
    24% identity, 100% coverage of query (66.6 bits)

nahN / BAE92169.1 2-hydroxymuconic semialdehyde hydrolase NahN from Pseudomonas putida (see 2 papers)
    28% identity, 91% coverage of query (66.2 bits)

6i8wB / Q9KJG6 Crystal structure of a membrane phospholipase a, a novel bacterial virulence factor (see paper)
    27% identity, 92% coverage of query (65.9 bits)

Q9KJG6 triacylglycerol lipase (EC 3.1.1.3) from Pseudomonas aeruginosa (see paper)
    27% identity, 92% coverage of query (65.9 bits)

8agsAAA / A0A1U9WZ52 8agsAAA
    25% identity, 85% coverage of query (65.9 bits)

5ng7B Novel epoxide hydrolases belonging to the alpha/beta hydrolases superfamily in metagenomes from hot environments
    25% identity, 85% coverage of query (65.9 bits)

8agnAAA Alpha/beta epoxide hydrolase
    25% identity, 85% coverage of query (65.9 bits)

8agmAAA Alpha/beta epoxide hydrolase
    25% identity, 85% coverage of query (65.9 bits)

8agpAAA Alpha/beta epoxide hydrolase
    25% identity, 85% coverage of query (65.9 bits)

NAP_BACSU / P96688 Uncharacterized carboxylesterase nap; EC 3.1.1.1 from Bacillus subtilis (strain 168)
    23% identity, 100% coverage of query (65.1 bits)

hppC / AAB81313.1 2-hydroxy-6-ketonona-2,4-dienoate hydrolase from Rhodococcus globerulus (see paper)
    27% identity, 95% coverage of query (65.1 bits)

5z7xA / A0A0M4AMQ0 Crystal structure of striga hermonthica htl4 (shhtl4) (see paper)
    25% identity, 90% coverage of query (64.7 bits)

4ihaA Crystal structure of rice dwarf14 (d14) in complex with a gr24 hydrolysis intermediate
    28% identity, 90% coverage of query (64.7 bits)

4ccwA / Q59248 Crystal structure of naproxen esterase (carboxylesterase np) from bacillus subtilis (see paper)
    24% identity, 98% coverage of query (64.3 bits)

D14_ORYSJ / Q10QA5 Strigolactone esterase D14; Protein DWARF 14; Protein DWARF 88; Protein HIGH-TILLERING DWARF 2; EC 3.1.-.- from Oryza sativa subsp. japonica (Rice) (see 11 papers)
    28% identity, 90% coverage of query (64.3 bits)

5zhtA Crystal structure of osd14 in complex with covalently bound kk073
    28% identity, 90% coverage of query (64.3 bits)

5zhrA Crystal structure of osd14 in complex with covalently bound kk094
    28% identity, 90% coverage of query (64.3 bits)

5yz7A Crystal structure of osd14 in complex with d-ring-opened 7'-carba-4bd
    28% identity, 90% coverage of query (64.3 bits)

5zhsA Crystal structure of osd14 in complex with covalently bound kk052
    28% identity, 90% coverage of query (64.3 bits)

6ap8A Crystal structure of rice d14 bound to 2-(2-methyl-3-nitroanilino) benzoic acid
    28% identity, 90% coverage of query (64.3 bits)

5dj5A Crystal structure of rice dwarf14 in complex with synthetic strigolactone gr24
    28% identity, 90% coverage of query (64.3 bits)

6brtA / A0A0D9Z3K8 F-box protein cth with hydrolase (see paper)
    28% identity, 90% coverage of query (63.9 bits)

estRB8 / CAE54381.1 carboxylesterase, partial from Oleispira antarctica (see paper)
estRB8 / CAE54384.1 carboxylesterase from Oleispira antarctica (see paper)
    24% identity, 92% coverage of query (63.2 bits)

cpo / GI|151186 chloroperoxidase; EC 1.11.1.10 from Burkholderia pyrrocinia (see 2 papers)
cpo / AAA02837.1 chloroperoxidase from Burkholderia pyrrocinia (see paper)
    27% identity, 89% coverage of query (63.2 bits)

CEEH1_CAEEL / G5EBI4 Epoxide hydrolase 1; CEEH1; EC 3.3.2.10 from Caenorhabditis elegans (see paper)
    20% identity, 98% coverage of query (63.2 bits)

P25026 Non-heme chloroperoxidase; Chloride peroxidase; Chloroperoxidase P; CPO-P; EC 1.11.1.- from Burkholderia pyrrocinia (Pseudomonas pyrrocinia)
    27% identity, 89% coverage of query (63.2 bits)

4o08A Crystal structure of bacillus megaterium epoxide hydrolase in complex with an inhibitor
    21% identity, 98% coverage of query (61.6 bits)

2d0dA Crystal structure of a meta-cleavage product hydrolase (cumd) a129v mutant
    22% identity, 92% coverage of query (61.2 bits)

5cbkA / A0A0M5I297 Crystal structure of the strigolactone receptor shhtl5 from striga hermonthica (see paper)
    24% identity, 90% coverage of query (61.2 bits)

4io0A / G9BEX6 Crystal structure of f128a mutant of an epoxide hydrolase from bacillus megaterium complexed with its product (r)-3-[1]naphthyloxy- propane-1,2-diol (see paper)
    21% identity, 98% coverage of query (60.8 bits)

3r3xA Crystal structure of the fluoroacetate dehalogenase rpa1163 - asp110asn/bromoacetate
    24% identity, 92% coverage of query (60.5 bits)

4g9eA Crystal structures of n-acyl homoserine lactonase aidh complexed with n-butanoyl homoserine
    26% identity, 91% coverage of query (60.1 bits)

1iunB / P96965 Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant hexagonal (see paper)
    21% identity, 93% coverage of query (60.1 bits)

8dvcA Receptor shhtl5 from striga hermonthica in complex with strigolactone agonist gr24
    24% identity, 90% coverage of query (60.1 bits)

1ukaA Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with (s)-2-methylbutyrate
    22% identity, 92% coverage of query (59.7 bits)

1uk9A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with isovalerate
    22% identity, 92% coverage of query (59.7 bits)

1uk8A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-valerate
    22% identity, 92% coverage of query (59.7 bits)

1uk7A Crystal structure of a meta-cleavage product hydrolase (cumd) complexed with n-butyrate
    22% identity, 92% coverage of query (59.7 bits)

1iupA Meta-cleavage product hydrolase from pseudomonas fluorescens ip01 (cumd) s103a mutant complexed with isobutyrates
    22% identity, 92% coverage of query (59.7 bits)

D14_ARATH / Q9SQR3 Strigolactone esterase D14; Protein DWARF 14; AtD14; EC 3.1.-.- from Arabidopsis thaliana (Mouse-ear cress) (see 8 papers)
    23% identity, 90% coverage of query (58.9 bits)

4g8bA / D2J2T6 Crystal structures of n-acyl homoserine lactonase aidh s102g mutant complexed with n-hexanoyl homoserine lactone (see paper)
    26% identity, 91% coverage of query (58.5 bits)

6o5jA Crystal structure of dad2 bound to quinazolinone derivative
    25% identity, 91% coverage of query (58.2 bits)

6ap7A Crystal structure of dad2 in complex with 2-(2-methyl-3-nitroanilino) benzoic acid
    25% identity, 91% coverage of query (58.2 bits)

6ap6A / J9U5U9 Crystal structure of dad2 in complex with tolfenamic acid (see paper)
    25% identity, 91% coverage of query (58.2 bits)

MhpC / b0349 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
mhpC / P77044 2-hydroxy-6-ketonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (strain K12) (see 10 papers)
MHPC_ECOLI / P77044 2-hydroxy-6-oxononadienedioate/2-hydroxy-6-oxononatrienedioate hydrolase; 2-hydroxy-6-ketonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4,7-triene-1,9-dioic acid 5,6-hydrolase; 2-hydroxy-6-oxonona-2,4-diene-1,9-dioic acid 5,6-hydrolase; EC 3.7.1.14 from Escherichia coli (strain K12) (see 4 papers)
P77044 2-hydroxy-6-oxonona-2,4-dienedioate hydrolase (EC 3.7.1.14) from Escherichia coli (see 4 papers)
    27% identity, 95% coverage of query (57.0 bits)

DAD2_PETHY / J9U5U9 Probable strigolactone esterase DAD2; Protein DECREASED APICAL DOMINANCE 2; EC 3.1.-.- from Petunia hybrida (Petunia) (see paper)
    24% identity, 94% coverage of query (56.6 bits)

5dnuA / A0A0M3PN85 Crystal structure of striga kai2-like protein in complex with karrikin (see paper)
    23% identity, 95% coverage of query (55.8 bits)

4jymA / Q9SZU7 Crystal structure of kai2 in complex with 3-methyl-2h-furo[2,3- c]pyran-2-one (see paper)
    21% identity, 89% coverage of query (55.1 bits)

KAI2_ARATH / Q9SZU7 Probable esterase KAI2; Protein DWARF-14-like; Protein D14-like; Protein HYPOSENSITIVE TO LIGHT; Protein KARRIKIN INSENSITIVE 2 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
    21% identity, 89% coverage of query (54.7 bits)

5z7wB / A0A0M4AV81 Crystal structure of striga hermonthica htl1 (shhtl1) (see paper)
    23% identity, 94% coverage of query (54.3 bits)

BioB / b3412 pimeloyl-acyl carrier protein methyl ester esterase (EC 3.1.1.85; EC 3.1.1.1) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
bioH / P13001 pimeloyl-acyl carrier protein methyl ester esterase (EC 3.1.1.85; EC 3.1.1.1) from Escherichia coli (strain K12) (see 8 papers)
BIOH_ECOLI / P13001 Pimeloyl-[acyl-carrier protein] methyl ester esterase; Biotin synthesis protein BioH; Carboxylesterase BioH; EC 3.1.1.85 from Escherichia coli (strain K12) (see 4 papers)
P13001 carboxylesterase (EC 3.1.1.1); pimelyl-[acyl-carrier protein] methyl ester esterase (EC 3.1.1.85) from Escherichia coli (see paper)
    26% identity, 94% coverage of query (53.1 bits)

5jzbA Crystal structure of hsad bound to 3,5-dichlorobenzene sulphonamide
    27% identity, 95% coverage of query (52.0 bits)

1m33A / P13001 Crystal structure of bioh at 1.7 a (see paper)
    26% identity, 94% coverage of query (52.0 bits)

7zm4A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclipostin-like inhibitor cyc31
    27% identity, 95% coverage of query (52.0 bits)

7zm3A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclipostin-like inhibitor cyc17
    27% identity, 95% coverage of query (52.0 bits)

7zm2A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclophostin-like inhibitor cyc8b
    27% identity, 95% coverage of query (52.0 bits)

7zm1A Crystal structure of hsad from mycobacterium tuberculosis in complex with cyclophostin-like inhibitor cyc7b
    27% identity, 95% coverage of query (52.0 bits)

5jzsB Hsad bound to 3,5-dichloro-4-hydroxybenzoic acid
    27% identity, 95% coverage of query (52.0 bits)

5jz9A / P9WNH5 Crystal structure of hsad bound to 3,5-dichloro-4- hydroxybenzenesulphonic acid (see paper)
    27% identity, 95% coverage of query (52.0 bits)

hsaD / P9WNH5 4,5-9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase monomer (EC 3.7.1.17) from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
HSAD_MYCTU / P9WNH5 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase; 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase; HOPDA hydrolase; Meta-cleavage product hydrolase; MCP hydrolase; EC 3.7.1.17; EC 3.7.1.8 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 4 papers)
P9WNH5 2,6-dioxo-6-phenylhexa-3-enoate hydrolase (EC 3.7.1.8) from Mycobacterium tuberculosis (see paper)
    27% identity, 95% coverage of query (51.6 bits)

4etwA Structure of the enzyme-acp substrate gatekeeper complex required for biotin synthesis
    25% identity, 94% coverage of query (51.2 bits)

5hzgA / Q9SQR3 The crystal structure of the strigolactone-induced atd14-d3-ask1 complex (see paper)
    22% identity, 89% coverage of query (50.8 bits)

2wufB Crystal structure of s114a mutant of hsad from mycobacterium tuberculosis in complex with 4,9dsha
    27% identity, 95% coverage of query (50.8 bits)

2wueB Crystal structure of s114a mutant of hsad from mycobacterium tuberculosis in complex with hopoda
    27% identity, 95% coverage of query (50.8 bits)

2wugA Crystal structure of s114a mutant of hsad from mycobacterium tuberculosis in complex with hopda
    27% identity, 95% coverage of query (50.4 bits)

7k38A Crystal structure of pisum sativum kai2 in complex with gr24-ent5ds product (see paper)
    21% identity, 89% coverage of query (49.3 bits)

8hgwA / Q2MHH5 Crystal structure of mehph in complex with mbp (see paper)
    26% identity, 92% coverage of query (48.5 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory