Searching for up to 100 curated homologs for AZOBR_RS06620 FitnessBrowser__azobra:AZOBR_RS06620 (330 a.a.)

Found high-coverage hits (≥70%) to 20 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

NUPN_BACSU / O05252 ABC transporter guanosine-binding protein NupN from Bacillus subtilis (strain 168) (see 2 papers)
    34% identity, 97% coverage of query (173 bits)

7x0rB / A3DFS3 Crystal structure of substrate binding protein lbp complexed wtih guanosine from clostridium thermocellum (see paper)
    35% identity, 89% coverage of query (167 bits)

TC 3.A.1.2.17 / D2BKA1 Basic membrane lipoprotein, component of General nucleoside uptake porter, NupABC/BmpA (transports all common nucleosides as well as 5-fluorocytidine, inosine, deoxyuridine and xanthosine) (Martinussen et al., 2010) (Most similar to 3.A.1.2.12). NupA is 506aas with two ABC (C) domains. NupB has 8 predicted TMSs, NupC has 9 or 10 predicted TMSs in a 4 + 1 (or 2) + 4 arrangement from Lactococcus lactis subsp. lactis (strain KF147) (see 2 papers)
    33% identity, 98% coverage of query (153 bits)

TMPC_TREPA / P29724 Membrane lipoprotein TmpC; Membrane protein C; 35 kDa antigen; Lipoprotein TpN35; Purine nucleoside receptor A; PnrA from Treponema pallidum (strain Nichols) (see paper)
TC 3.A.1.2.10 / P29724 TmpC aka Membrane protein C aka 35 kDa antigen aka Lipoprotein TpN35, component of The purine nucleoside permease (probably transports guanosine, adenosine, 2'-deoxyguanosine, inosine and xanthosine with decreasing affinity in this order) from Treponema pallidum (see 2 papers)
    35% identity, 97% coverage of query (150 bits)

2fqwA / P29724 Pnra from treponema pallidum as purified from e. Coli (bound to inosine) (see paper)
    35% identity, 90% coverage of query (148 bits)

2fqyA Pnra from treponema pallidum complexed with adenosine.
    35% identity, 90% coverage of query (148 bits)

2fqxA Pnra from treponema pallidum complexed with guanosine
    35% identity, 90% coverage of query (148 bits)

BMPA_LACLM / A2RK47 ABC transporter nucleoside-binding protein BmpA from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    31% identity, 98% coverage of query (146 bits)

6shuA / E4S1L1 Borrelia burgdorferi bmpd nucleoside binding protein bound to adenosine (see paper)
    31% identity, 78% coverage of query (130 bits)

4pevA / Q9Y8P1 Crystal structure of abc transporter system solute-binding proteins from aeropyrum pernix k1
    30% identity, 88% coverage of query (129 bits)

6y9uA / A0A0H2UPF3 Crystal structure of pnra from s. Pneumoniae in complex with adenosine (see paper)
    34% identity, 89% coverage of query (125 bits)

6ya3A Crystal structure of pnra from s. Pneumoniae in complex with guanosine
    34% identity, 89% coverage of query (125 bits)

6yagA Crystal structure of pnra from s. Pneumoniae in complex with thymidine
    34% identity, 89% coverage of query (125 bits)

6ya4A Crystal structure of pnra from s. Pneumoniae in complex with cytidine
    34% identity, 89% coverage of query (125 bits)

6yabAAA Lipoprotein
    34% identity, 89% coverage of query (125 bits)

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Build an alignment for AZOBR_RS06620 and 15 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

3s99A / Q2YKI6 Crystal structure of a basic membrane lipoprotein from brucella melitensis, iodide soak
    25% identity, 75% coverage of query (79.0 bits)

6piiA / Q936X6 The evolving story of atzt, a periplasmic binding protein (see paper)
    24% identity, 77% coverage of query (75.1 bits)

6pi6A The evolving story of atzt, a periplasmic binding protein
    24% identity, 77% coverage of query (75.1 bits)

6piiC The evolving story of atzt, a periplasmic binding protein
    24% identity, 77% coverage of query (74.7 bits)

RFUA_TREPA / Q56328 ABC transporter riboflavin-binding protein RfuA; Membrane lipoprotein TpN38(b) from Treponema pallidum (strain Nichols) (see paper)
TC 3.A.1.2.28 / R9UW99 ABC superfamily ATP binding cassette transporter, membrane protein, component of Riboflavin uptake ABC transporter, RfuABCD from Treponema pallidum (strain Nichols)
    24% identity, 98% coverage of query (67.4 bits)

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