Sites on a Tree

 

Searching for up to 100 curated homologs for AZOBR_RS06955 FitnessBrowser__azobra:AZOBR_RS06955 (362 a.a.)

Found high-coverage hits (≥70%) to 7 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

TSGBD_HALVD / D4GPW2 Glucose ABC transporter permease protein TsgB13 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
    39% identity, 96% coverage of query (214 bits)

NUPP_BACSU / O05254 Guanosine ABC transporter permease protein NupP from Bacillus subtilis (strain 168) (see paper)
    31% identity, 91% coverage of query (143 bits)

TC 3.A.1.2.12 / Q8DU38 RnsC, component of The (deoxy)ribonucleoside permease; probably takes up all deoxy- and ribonucleosides (cytidine, uridine, adenosine and toxic analogues, fluorocytidine and fluorouridine tested), but not ribose or nucleobases from Streptococcus mutans (see paper)
    30% identity, 93% coverage of query (142 bits)

NUPB_LACLM / A2RKA6 Nucleoside ABC transporter permease protein NupB from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
TC 3.A.1.2.17 / A2RKA6 Purine/cytidine ABC transporter permease protein, component of General nucleoside uptake porter, NupABC/BmpA (transports all common nucleosides as well as 5-fluorocytidine, inosine, deoxyuridine and xanthosine) (Martinussen et al., 2010) (Most similar to 3.A.1.2.12). NupA is 506aas with two ABC (C) domains. NupB has 8 predicted TMSs, NupC has 9 or 10 predicted TMSs in a 4 + 1 (or 2) + 4 arrangement from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    30% identity, 88% coverage of query (130 bits)

Build an alignment

Build an alignment for AZOBR_RS06955 and 4 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

TC 3.A.1.2.10 / O83342 Ribose/galactose ABC transporter, permease protein aka RbsC-1, component of The purine nucleoside permease (probably transports guanosine, adenosine, 2'-deoxyguanosine, inosine and xanthosine with decreasing affinity in this order) from Treponema pallidum (see paper)
    29% identity, 93% coverage of query (128 bits)

TC 3.A.1.2.12 / Q8DU39 RnsD, component of The (deoxy)ribonucleoside permease; probably takes up all deoxy- and ribonucleosides (cytidine, uridine, adenosine and toxic analogues, fluorocytidine and fluorouridine tested), but not ribose or nucleobases from Streptococcus mutans (see paper)
    27% identity, 70% coverage of query (59.7 bits)

NUPC_LACLM / A2RKA5 Nucleoside ABC transporter permease protein NupC from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
TC 3.A.1.2.17 / A2RKA5 Purine/cytidine ABC transporter permease protein, component of General nucleoside uptake porter, NupABC/BmpA (transports all common nucleosides as well as 5-fluorocytidine, inosine, deoxyuridine and xanthosine) (Martinussen et al., 2010) (Most similar to 3.A.1.2.12). NupA is 506aas with two ABC (C) domains. NupB has 8 predicted TMSs, NupC has 9 or 10 predicted TMSs in a 4 + 1 (or 2) + 4 arrangement from Lactococcus lactis subsp. cremoris (strain MG1363) (see paper)
    25% identity, 70% coverage of query (56.2 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory