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Searching for up to 100 curated homologs for AZOBR_RS07885 FitnessBrowser__azobra:AZOBR_RS07885 (433 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

oxlT / Q51330 oxalate:formate antiporter from Oxalobacter formigenes (see 8 papers)
OXLT_OXAFO / Q51330 Oxalate:formate antiporter; OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein from Oxalobacter formigenes (see 5 papers)
    36% identity, 99% coverage of query (241 bits)

8hpkA / Q51330 Crystal structure of the bacterial oxalate transporter oxlt in an oxalate-bound occluded form (see paper)
    37% identity, 93% coverage of query (234 bits)

6zgsA / A0LNN5 Crystal structure of a mfs transporter with bound 3-phenylpropanoic acid at 2.39 angstroem resolution
    30% identity, 94% coverage of query (149 bits)

6zguA Crystal structure of a mfs transporter with bound 3-(2-methylphenyl) propanoic acid at 2.41 angstroem resolution
    30% identity, 94% coverage of query (149 bits)

6zgtA Crystal structure of a mfs transporter with bound 2-naphthoic acid at 2.39 angstroem resolution
    30% identity, 94% coverage of query (149 bits)

Build an alignment

Build an alignment for AZOBR_RS07885 and 5 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

SFMCT_SYNFM / A0LNN5 L-lactate transporter; SfMCT from Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) (see paper)
    29% identity, 93% coverage of query (145 bits)

6zgrA Crystal structure of a mfs transporter with bound 1- hydroxynaphthalene-2-carboxylic acid at 2.67 angstroem resolution
    30% identity, 94% coverage of query (140 bits)

6g9xA Crystal structure of a mfs transporter at 2.54 angstroem resolution
    30% identity, 94% coverage of query (138 bits)

6zguB Crystal structure of a mfs transporter with bound 3-(2-methylphenyl) propanoic acid at 2.41 angstroem resolution
    31% identity, 88% coverage of query (135 bits)

6zgtB Crystal structure of a mfs transporter with bound 2-naphthoic acid at 2.39 angstroem resolution
    31% identity, 88% coverage of query (135 bits)

6zgsB Crystal structure of a mfs transporter with bound 3-phenylpropanoic acid at 2.39 angstroem resolution
    31% identity, 88% coverage of query (135 bits)

6g9xB / A0LNN5 Crystal structure of a mfs transporter at 2.54 angstroem resolution (see paper)
    30% identity, 89% coverage of query (125 bits)

6zgrB Crystal structure of a mfs transporter with bound 1- hydroxynaphthalene-2-carboxylic acid at 2.67 angstroem resolution
    30% identity, 88% coverage of query (123 bits)

YhjX / b3547 putative transporter YhjX from Escherichia coli K-12 substr. MG1655 (see 10 papers)
YHJX_ECOLI / P37662 Uncharacterized MFS-type transporter YhjX from Escherichia coli (strain K12) (see 3 papers)
TC 2.A.1.11.3 / P37662 Inner membrane protein BtsT or YhjX (probably a pyruvate:proton symporter that can also function as an exporter) from Escherichia coli (strain K12) (see 4 papers)
    26% identity, 83% coverage of query (107 bits)

SAUU_CUPNH / Q0K843 Probable sulfoacetate transporter SauU from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (Ralstonia eutropha) (see paper)
    24% identity, 94% coverage of query (59.7 bits)

MOT13_HUMAN / Q7RTY0 Monocarboxylate transporter 13; MCT 13; Solute carrier family 16 member 13 from Homo sapiens (Human) (see paper)
TC 2.A.1.13.17 / Q7RTY0 Monocarboxylate transporter 13 (MCT 13) (Solute carrier family 16 member 13) from Homo sapiens (see 2 papers)
    25% identity, 78% coverage of query (50.8 bits)

FDB26_GIBM7 / W7MTI3 MFS-type transporter FVEG_12626; Fusarium detoxification of benzoxazolinone cluster 2 protein FVEG_12626; FDB2 cluster protein FVEG_12626 from Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) (see 2 papers)
    21% identity, 73% coverage of query (47.0 bits)

MOT2_HUMAN / O60669 Monocarboxylate transporter 2; MCT 2; Solute carrier family 16 member 7 from Homo sapiens (Human) (see 3 papers)
    24% identity, 82% coverage of query (47.0 bits)

TC 2.A.1.13.5 / O60669 Low affinity monocarboxylate transporter-2 (MCT2). Transports γ-hydroxybutyrate (Wang and Morris, 2007). MCT2 requires the ancillary protein, embigin (Q6PCB8; 8.A.23.1.2) for plasma membrane localization (Ovens et al., 2010). It is present in neurons but not astrocytes where the low affinity MCT1 and MCT4 predominate (Hertz and Dienel 2013). Partially localizes to the peroxysomal membrane (Visser et al. 2007). MCT1 is a negative regulator and MCT2 a positive regulator of osteoclast differentiation, while MCT2 is required for bone resorption by osteoclasts from Homo sapiens (Human) (see 2 papers)
    24% identity, 82% coverage of query (46.2 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory