Searching for up to 100 curated homologs for AZOBR_RS07945 FitnessBrowser__azobra:AZOBR_RS07945 (432 a.a.)
Found high-coverage hits (≥70%) to 21 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
oxlT / Q51330 oxalate:formate antiporter from Oxalobacter formigenes (see 8 papers)
OXLT_OXAFO / Q51330 Oxalate:formate antiporter; OFA; Oxalate:formate antiport protein; Oxalate:formate exchange protein from Oxalobacter formigenes (see 5 papers)
36% identity, 98% coverage of query (238 bits)
8hpkA / Q51330 Crystal structure of the bacterial oxalate transporter oxlt in an oxalate-bound occluded form (see paper)
36% identity, 93% coverage of query (233 bits)
6zgsA / A0LNN5 Crystal structure of a mfs transporter with bound 3-phenylpropanoic acid at 2.39 angstroem resolution
31% identity, 94% coverage of query (159 bits)
6zguA Crystal structure of a mfs transporter with bound 3-(2-methylphenyl) propanoic acid at 2.41 angstroem resolution
31% identity, 94% coverage of query (159 bits)
6zgtA Crystal structure of a mfs transporter with bound 2-naphthoic acid at 2.39 angstroem resolution
31% identity, 94% coverage of query (159 bits)
SFMCT_SYNFM / A0LNN5 L-lactate transporter; SfMCT from Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB) (see paper)
30% identity, 95% coverage of query (150 bits)
6zgrA Crystal structure of a mfs transporter with bound 1- hydroxynaphthalene-2-carboxylic acid at 2.67 angstroem resolution
31% identity, 94% coverage of query (148 bits)
6g9xA Crystal structure of a mfs transporter at 2.54 angstroem resolution
31% identity, 94% coverage of query (145 bits)
6zguB Crystal structure of a mfs transporter with bound 3-(2-methylphenyl) propanoic acid at 2.41 angstroem resolution
31% identity, 88% coverage of query (143 bits)
6zgtB Crystal structure of a mfs transporter with bound 2-naphthoic acid at 2.39 angstroem resolution
31% identity, 88% coverage of query (143 bits)
6zgsB Crystal structure of a mfs transporter with bound 3-phenylpropanoic acid at 2.39 angstroem resolution
31% identity, 88% coverage of query (143 bits)
6g9xB / A0LNN5 Crystal structure of a mfs transporter at 2.54 angstroem resolution (see paper)
30% identity, 89% coverage of query (134 bits)
6zgrB Crystal structure of a mfs transporter with bound 1- hydroxynaphthalene-2-carboxylic acid at 2.67 angstroem resolution
30% identity, 88% coverage of query (129 bits)
Build an alignment for AZOBR_RS07945 and 13 homologs with ≥ 30% identity
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YhjX / b3547 putative transporter YhjX from Escherichia coli K-12 substr. MG1655 (see 10 papers)
YHJX_ECOLI / P37662 Uncharacterized MFS-type transporter YhjX from Escherichia coli (strain K12) (see 3 papers)
TC 2.A.1.11.3 / P37662 Inner membrane protein BtsT or YhjX (probably a pyruvate:proton symporter that can also function as an exporter) from Escherichia coli (strain K12) (see 4 papers)
26% identity, 87% coverage of query (114 bits)
TC 2.A.1.11.5 / Q08791 MFS-type transporter YcxA (ORF5) of 408 aas and 12 TMSs from Bacillus subtilis (strain 168) (see 4 papers)
23% identity, 94% coverage of query (60.1 bits)
MOT2_HUMAN / O60669 Monocarboxylate transporter 2; MCT 2; Solute carrier family 16 member 7 from Homo sapiens (Human) (see 3 papers)
23% identity, 83% coverage of query (53.1 bits)
MOT12_HUMAN / Q6ZSM3 Monocarboxylate transporter 12; MCT 12; Creatine transporter 2; CRT2; Solute carrier family 16 member 12 from Homo sapiens (Human) (see 7 papers)
21% identity, 78% coverage of query (52.0 bits)
TC 2.A.1.13.5 / O60669 Low affinity monocarboxylate transporter-2 (MCT2). Transports γ-hydroxybutyrate (Wang and Morris, 2007). MCT2 requires the ancillary protein, embigin (Q6PCB8; 8.A.23.1.2) for plasma membrane localization (Ovens et al., 2010). It is present in neurons but not astrocytes where the low affinity MCT1 and MCT4 predominate (Hertz and Dienel 2013). Partially localizes to the peroxysomal membrane (Visser et al. 2007). MCT1 is a negative regulator and MCT2 a positive regulator of osteoclast differentiation, while MCT2 is required for bone resorption by osteoclasts from Homo sapiens (Human) (see 2 papers)
23% identity, 83% coverage of query (51.6 bits)
MFS1_OPHS1 / A0A0C4VYV1 MFS-type transporter 1 from Ophiocordyceps sp. (strain BCC 1869) (Entomopathogenic fungus) (see 5 papers)
24% identity, 77% coverage of query (50.8 bits)
TC 2.A.1.8.11 / Q93PW1 NarK, component of The 24 TMS, 2 domain, NarK1-NarK2 porter (NarK1 = a NO3-/H+ symporter; NarK2 = a NO3-/NO2- antiporter) from Paracoccus pantotrophus (Thiosphaera pantotropha) (see paper)
25% identity, 94% coverage of query (48.9 bits)
MOT12_RAT / D4A734 Monocarboxylate transporter 12; MCT 12; Solute carrier family 16 member 12 from Rattus norvegicus (Rat) (see 3 papers)
22% identity, 74% coverage of query (48.5 bits)
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Lawrence Berkeley National Laboratory