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Searching for up to 100 curated homologs for AZOBR_RS08245 FitnessBrowser__azobra:AZOBR_RS08245 (294 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

Removed hits that are identical to the query, leaving 99

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

braF / CAB75551.1 ATPase from Rhizobium leguminosarum bv. viciae (see 2 papers)
    66% identity, 90% coverage of query (371 bits)

Pf6N2E2_2925 ABC transporter for L-leucine/L-isoleucine/L-phenylalanine/D-alanine, ATPase component 1 LivG from Pseudomonas fluorescens FW300-N2E2
    54% identity, 88% coverage of query (284 bits)

TC 3.A.1.4.8 / P21629 High-affinity branched-chain amino acid transport ATP-binding protein BraF, component of Branched chain amino acid uptake transporter. Transports alanine from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    53% identity, 89% coverage of query (283 bits)

LivG / b3455 branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG (EC 7.4.2.2) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
LivG / P0A9S7 branched chain amino acid/phenylalanine ABC transporter ATP binding subunit LivG (EC 7.4.2.2) from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.4.1 / P0A9S7 High-affinity branched-chain amino acid transport ATP-binding protein LivG aka B3455, component of Leucine; leucine/isoleucine/valine porter from Escherichia coli (see 4 papers)
    53% identity, 89% coverage of query (274 bits)

TC 3.A.1.4.10 / Q8DQH8 ABC transporter ATP-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    48% identity, 88% coverage of query (224 bits)

Ac3H11_1693 ABC transporter for glutamine/isoleucine/leucine/phenylalanine/proline/serine/tyrosine, ATPase component 1 from Acidovorax sp. GW101-3H11
    45% identity, 88% coverage of query (213 bits)

HSERO_RS00895 L-proline ABC transporter, ATPase component 1 from Herbaspirillum seropedicae SmR1
    46% identity, 88% coverage of query (205 bits)

TC 3.A.1.4.11 / Q6N8W1 Putative branched-chain amino acid transport system ATP-binding protein, component of The phenylpropeneoid uptake porter, CouPSTW from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009)
    46% identity, 89% coverage of query (195 bits)

PGA1_c12640 D-lactate transporter, ATP-binding component from Phaeobacter inhibens BS107
    37% identity, 88% coverage of query (169 bits)

TC 3.A.1.4.6 / Q7A2H0 NatA, component of The neutral amino acid permease, N-1 (transports pro, phe, leu, gly, ala, ser, gln and his, but gln and his are not transported via NatB) (see paper)
    38% identity, 88% coverage of query (158 bits)

TC 3.A.1.4.2 / Q55164 NatA aka BRAF aka SLR0467, component of Leucine/proline/alanine/serine/glycine (and possibly histidine) porter, NatABCDE (see paper)
    37% identity, 89% coverage of query (153 bits)

TC 3.A.1.4.3 / Q8VM83 BraF aka Bra2F, component of General L- (and D-)amino acid uptake porter (transports acidic, basic, polar, semipolar and hydrophobic amino acids). The amino and carboxyl groups do not need to be α since γ-aminobutyric acid (GABA) is a substrate. The system may function with additional binding proteins since L-alanine uptake is not dependent on BraC from Rhizobium leguminosarum (biovar viciae) (see paper)
    34% identity, 88% coverage of query (148 bits)

TC 3.A.1.4.9 / Q0S719 ABC amino acid transporter, ATP-binding, component of Uptake transporter, CamABCD of cholate (steroid) metabolites, 1β(2'-propanoate)-3aα-H-4α(3"(R)-hydroxy-3"-propanoate)-7aβ-methylhexahydro-5-indanone and a desaturated analog from Rhodococcus sp. (strain RHA1)
    37% identity, 91% coverage of query (142 bits)

TC 3.A.1.4.7 / Q92TN3 ABC transporter, ATP-binding protein, component of The protocatechuate (3,4-dihydroxybenzoate) uptake porter, PcaMNVWX from Rhizobium meliloti (strain 1021)
    36% identity, 90% coverage of query (137 bits)

1g6hA / Q58663 Crystal structure of the adp conformation of mj1267, an atp-binding cassette of an abc transporter (see paper)
    33% identity, 89% coverage of query (133 bits)

1g9xB Characterization of the twinning structure of mj1267, an atp-binding cassette of an abc transporter
    33% identity, 89% coverage of query (130 bits)

TC 3.A.1.4.10 / Q8DQH7 ABC transporter ATP-binding protein-branched chain amino acid transport, component of The branched chain hydrophobic amino acid transporter, LivJFGHM from Streptococcus pneumoniae (strain ATCC BAA-255 / R6)
    33% identity, 88% coverage of query (120 bits)

TC 3.A.1.2.22 / Q8G3R0 ATP binding protein of ABC transporter for pentoses, component of ABC sugar transporter that plays a role in the probiotic benefits through acetate production from Bifidobacterium longum (strain NCC 2705)
    34% identity, 81% coverage of query (118 bits)

AO356_00465 ABC transporter for D-Glucosamine, putative ATPase component from Pseudomonas fluorescens FW300-N2C3
    30% identity, 84% coverage of query (112 bits)

Pf6N2E2_2050 ABC transporter for D-Glucosamine, putative ATPase component from Pseudomonas fluorescens FW300-N2E2
    30% identity, 84% coverage of query (112 bits)

TC 3.A.1.4.5 / Q8NRV8 UrtD, component of The high affinity urea/thiourea/hydroxyurea porter from Corynebacterium glutamicum (see paper)
    33% identity, 87% coverage of query (110 bits)

Build an alignment

Build an alignment for AZOBR_RS08245 and 21 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

YhdZ / b3271 putative ABC transporter ATP-binding subunit YhdZ from Escherichia coli K-12 substr. MG1655 (see 4 papers)
yhdZ / RF|NP_417737 uncharacterized amino-acid ABC transporter ATP-binding protein yhdZ from Escherichia coli K12 (see 3 papers)
    27% identity, 88% coverage of query (110 bits)

4yerA / Q9X1C3 Crystal structure of an abc transporter atp-binding protein (tm_1403) from thermotoga maritima msb8 at 2.35 a resolution
    30% identity, 84% coverage of query (105 bits)

6mjpA / O30650 Lptb(e163q)fgc from vibrio cholerae (see paper)
    27% identity, 88% coverage of query (103 bits)

4ymuJ / Q8RCC2 Crystal structure of an amino acid abc transporter complex with arginines and atps (see paper)
    28% identity, 83% coverage of query (103 bits)

6s8nB Cryo-em structure of lptb2fgc in complex with lipopolysaccharide
    30% identity, 88% coverage of query (103 bits)

6s8gA Cryo-em structure of lptb2fgc in complex with amp-pnp
    30% identity, 88% coverage of query (103 bits)

6mbnA / P0A9V1 Lptb e163q in complex with atp (see paper)
    29% identity, 88% coverage of query (102 bits)

Q8TTZ3 ABC-type molybdate transporter (EC 7.3.2.5) from Methanosarcina acetivorans (see paper)
3d31A / Q8TTZ3 Modbc from methanosarcina acetivorans (see paper)
    30% identity, 85% coverage of query (101 bits)

6mhzA Vanadate trapped cryo-em structure of e.Coli lptb2fg transporter
    30% identity, 87% coverage of query (100 bits)

7ahhC Opua inhibited inward-facing, sbd docked
    26% identity, 91% coverage of query (99.4 bits)

7aheC / Q9KIF7 Opua inhibited inward facing (see paper)
    26% identity, 91% coverage of query (99.4 bits)

7d0aB Acinetobacter mlafedb complex in adp-vanadate trapped vclose conformation
    29% identity, 84% coverage of query (99.0 bits)

7d08B / A0A086HZU3 Acinetobacter mlafedb complex in atp-bound vtrans1 conformation (see paper)
    29% identity, 84% coverage of query (99.0 bits)

6b89A E. Coli lptb in complex with adp and novobiocin
    29% identity, 87% coverage of query (98.6 bits)

4p31A Crystal structure of a selenomethionine derivative of e. Coli lptb in complex with adp-magensium
    29% identity, 87% coverage of query (98.6 bits)

7ahdC Opua (e190q) occluded
    27% identity, 82% coverage of query (97.8 bits)

6z5uK Cryo-em structure of the a. Baumannii mlabdef complex bound to appnhp
    29% identity, 83% coverage of query (97.8 bits)

PotA / b1126 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11; EC 7.6.2.16) from Escherichia coli K-12 substr. MG1655 (see 5 papers)
PotA / P69874 spermidine preferential ABC transporter ATP binding subunit (EC 7.6.2.11) from Escherichia coli (strain K12) (see 5 papers)
POTA_ECOLI / P69874 Spermidine/putrescine import ATP-binding protein PotA; EC 7.6.2.11 from Escherichia coli (strain K12) (see 6 papers)
TC 3.A.1.11.1 / P69874 Spermidine/putrescine import ATP-binding protein PotA aka B1126, component of Polyamine (putrescine/spermidine) uptake porter from Escherichia coli (see 9 papers)
potA / MB|P69874 spermidine/putrescine ABC transporter, ATP-binding protein PotA; EC 3.6.3.31 from Escherichia coli K12 (see 10 papers)
    27% identity, 91% coverage of query (97.4 bits)

6b8bA E. Coli lptb in complex with adp and a novobiocin derivative
    29% identity, 87% coverage of query (97.1 bits)

1ji0A / Q9X0M3 Crystal structure analysis of the abc transporter from thermotoga maritima
    26% identity, 89% coverage of query (94.7 bits)

4u00A / Q5SJ55 Crystal structure of ttha1159 in complex with adp (see paper)
    29% identity, 85% coverage of query (92.8 bits)

8i6rB / Q9I6C0 Cryo-em structure of pseudomonas aeruginosa ftse(e163q)x/envc complex with atp in peptidisc (see paper)
    28% identity, 82% coverage of query (92.4 bits)

1vciA / O57758 Crystal structure of the atp-binding cassette of multisugar transporter from pyrococcus horikoshii ot3 complexed with atp (see paper)
    23% identity, 88% coverage of query (89.4 bits)

3c4jA Abc protein artp in complex with atp-gamma-s
    26% identity, 83% coverage of query (89.4 bits)

3c41J / D0VWX4 Abc protein artp in complex with amp-pnp/mg2+
    26% identity, 83% coverage of query (89.4 bits)

2olkA Abc protein artp in complex with adp-beta-s
    26% identity, 83% coverage of query (89.4 bits)

2oljA Abc protein artp in complex with adp/mg2+
    26% identity, 83% coverage of query (89.4 bits)

HISP_SALTY / P02915 Histidine/lysine/arginine/ornithine transport ATP-binding protein HisP; EC 7.4.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see 4 papers)
TC 3.A.1.3.1 / P02915 HisP aka STM2351, component of Histidine/arginine/lysine/ornithine porter (Heuveling et al. 2014). In contrast to some homologous homodimeric systems, the heterodimeric histidine transporter of Salmonella enterica Typhimurium from Salmonella typhimurium (see 3 papers)
RF|NP_461293.1 histidine transport atp-binding protein hisp from Salmonella enterica subsp. enterica serovar Typhimurium (see 4 papers)
    28% identity, 87% coverage of query (87.8 bits)

7z15I / P16678 E. Coli c-p lyase bound to a phnk/phnl dual abc dimer and adp + pi (see paper)
    29% identity, 85% coverage of query (87.4 bits)

1b0uA / P02915 Atp-binding subunit of the histidine permease from salmonella typhimurium (see paper)
    29% identity, 86% coverage of query (87.4 bits)

7z18I E. Coli c-p lyase bound to a phnk abc dimer and atp
    29% identity, 85% coverage of query (87.0 bits)

7z16I E. Coli c-p lyase bound to phnk/phnl dual abc dimer with amppnp and phnk e171q mutation
    28% identity, 85% coverage of query (86.3 bits)

3puyA Crystal structure of an outward-facing mbp-maltose transporter complex bound to amp-pnp after crystal soaking of the pretranslocation state
    25% identity, 92% coverage of query (85.5 bits)

3puxA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-bef3
    25% identity, 92% coverage of query (85.5 bits)

3puwA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-alf4
    25% identity, 92% coverage of query (85.5 bits)

3puvA Crystal structure of an outward-facing mbp-maltose transporter complex bound to adp-vo4
    25% identity, 92% coverage of query (85.5 bits)

MalK / b4035 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli K-12 substr. MG1655 (see 31 papers)
MalK / P68187 maltose ABC transporter ATP binding subunit (EC 7.5.2.1) from Escherichia coli (strain K12) (see 29 papers)
MALK_ECOLI / P68187 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Escherichia coli (strain K12) (see 6 papers)
P68187 ABC-type maltose transporter (subunit 3/3) (EC 7.5.2.1) from Escherichia coli (see paper)
TC 3.A.1.1.1 / P68187 Maltose/maltodextrin import ATP-binding protein MalK aka B4035, component of Maltooligosaccharide porter. The 3-D structure has been reported by Oldham et al. (2007). An altering access mechanism has been suggested for the maltose transporter resulting from rigid-body rotations (Khare et al., 2009). Bordignon et al. (2010) and Schneider et al. (2012) have reviewed the extensive knowledge available on MalEFGK2, its mode of action and its regulatory interactions from Escherichia coli (see 17 papers)
malK / RF|NP_418459 maltose/maltodextrin import ATP-binding protein malK; EC 3.6.3.19 from Escherichia coli K12 (see 18 papers)
    25% identity, 92% coverage of query (85.5 bits)

1q12A Crystal structure of the atp-bound e. Coli malk
    25% identity, 92% coverage of query (85.5 bits)

2awnB / P68187 Crystal structure of the adp-mg-bound e. Coli malk (crystallized with atp-mg) (see paper)
    25% identity, 92% coverage of query (85.5 bits)

4hluA / Q9WY65 Structure of the ecfa-a' heterodimer bound to adp (see paper)
    30% identity, 84% coverage of query (84.3 bits)

5x40A / O68106 Structure of a cbio dimer bound with amppcp (see paper)
    30% identity, 87% coverage of query (84.3 bits)

ECFA1_STRT2 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA1; ECF transporter A component EcfA1; EC 7.-.-.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M243 Energy-coupling factor transporter ATP-binding protein EcfA 2, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
    30% identity, 78% coverage of query (84.0 bits)

ABCAC_MOUSE / E9Q876 Glucosylceramide transporter ABCA12; ATP-binding cassette sub-family A member 12; EC 7.6.2.1 from Mus musculus (Mouse) (see 9 papers)
    26% identity, 80% coverage of query (83.6 bits)

8bmpB / Q1GBI9 Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp (see paper)
    28% identity, 82% coverage of query (83.6 bits)

5d3mB Folate ecf transporter: amppnp bound state
    28% identity, 82% coverage of query (83.6 bits)

1oxvD Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    27% identity, 86% coverage of query (82.8 bits)

1oxvA Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus
    27% identity, 86% coverage of query (82.8 bits)

GLCV_SACS2 / Q97UY8 Glucose import ATP-binding protein GlcV; EC 7.5.2.- from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 3 papers)
TC 3.A.1.1.13 / Q97UY8 GlcV, component of Glucose, mannose, galactose porter from Sulfolobus solfataricus (see 3 papers)
1oxuA / Q97UY8 Crystal structure of glcv, the abc-atpase of the glucose abc transporter from sulfolobus solfataricus (see paper)
    27% identity, 86% coverage of query (82.8 bits)

8igqA / O05779 Cryo-em structure of mycobacterium tuberculosis adp bound ftsex/ripc complex in peptidisc (see paper)
    27% identity, 82% coverage of query (82.8 bits)

8iddA Cryo-em structure of mycobacterium tuberculosis atp bound ftsex/ripc complex in peptidisc
    27% identity, 82% coverage of query (82.8 bits)

FTSE_MYCTA / A5U7B7 Cell division ATP-binding protein FtsE from Mycobacterium tuberculosis (strain ATCC 25177 / H37Ra) (see 2 papers)
    27% identity, 82% coverage of query (82.4 bits)

RbsA / b3749 ribose ABC transporter ATP binding subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
RbsA / P04983 ribose ABC transporter ATP binding subunit from Escherichia coli (strain K12) (see 2 papers)
RBSA_ECOLI / P04983 Ribose import ATP-binding protein RbsA; EC 7.5.2.7 from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.2.1 / P04983 RbsA aka B3749, component of Ribose porter from Escherichia coli (see 6 papers)
rbsA / GB|AAC76772.1 ribose transport, ATP-binding protein RbsA; EC 3.6.3.17 from Escherichia coli K12 (see 7 papers)
    26% identity, 92% coverage of query (82.4 bits)

8bmsB Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
    28% identity, 82% coverage of query (82.4 bits)

MALK_SALTY / P19566 Maltose/maltodextrin import ATP-binding protein MalK; EC 7.5.2.1 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    25% identity, 92% coverage of query (82.4 bits)

8bmsA Cryo-em structure of the mutant solitary ecf module 2eq in msp2n2 lipid nanodiscs in the atpase closed and atp-bound conformation
    25% identity, 83% coverage of query (81.6 bits)

7chaI / Q9HVW1 Cryo-em structure of p.Aeruginosa mlafebd with amppnp (see paper)
    26% identity, 89% coverage of query (81.6 bits)

5xu1B / Q8DQF8 Structure of a non-canonical abc transporter from streptococcus pneumoniae r6 (see paper)
    27% identity, 75% coverage of query (81.3 bits)

4zirA Crystal structure of ecfaa' heterodimer bound to amppnp
    29% identity, 84% coverage of query (80.9 bits)

5d3mA / Q1GBJ0 Folate ecf transporter: amppnp bound state (see paper)
    26% identity, 83% coverage of query (80.5 bits)

MetN / b0199 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
MetN / P30750 L-methionine/D-methionine ABC transporter ATP binding subunit (EC 7.4.2.11) from Escherichia coli (strain K12) (see 3 papers)
METN_ECOLI / P30750 Methionine import ATP-binding protein MetN; EC 7.4.2.11 from Escherichia coli (strain K12) (see 7 papers)
P30750 ABC-type methionine transporter (subunit 2/2) (EC 7.4.2.11) from Escherichia coli (see 3 papers)
TC 3.A.1.24.1 / P30750 MetN, D-methionine transport ATP-binding protein, component of The L- and D-methionine porter (also transports formyl-L-methionine and other methionine derivatives) (Zhang et al., 2003). The 3.7A structure of MetNI has been solved. An allosteric regulatory mechanism operates at the level of transport activity, so increased intracellular levels of the transported ligand stabilize an inward-facing, ATPase-inactive state of MetNI to inhibit further ligand translocation into the cell from Escherichia coli (see 5 papers)
    29% identity, 80% coverage of query (79.7 bits)

8bmpA Cryo-em structure of the folate-specific ecf transporter complex in msp2n2 lipid nanodiscs bound to atp and adp
    27% identity, 78% coverage of query (79.7 bits)

7w79A Heme exporter hrtba in complex with mn-amppnp
    28% identity, 72% coverage of query (79.3 bits)

7w78A / Q6NEF2 Heme exporter hrtba in complex with mg-amppnp (see paper)
    28% identity, 72% coverage of query (79.0 bits)

ABCAD_MOUSE / Q5SSE9 ATP-binding cassette sub-family A member 13; EC 7.6.2.- from Mus musculus (Mouse) (see 3 papers)
    29% identity, 79% coverage of query (79.0 bits)

6cvlD / P30750 Crystal structure of the escherichia coli atpgs-bound metni methionine abc transporter in complex with its metq binding protein (see paper)
    29% identity, 80% coverage of query (79.0 bits)

3tuzC Inward facing conformations of the metni methionine abc transporter: cy5 semet soak crystal form
    29% identity, 80% coverage of query (79.0 bits)

3tuiC Inward facing conformations of the metni methionine abc transporter: cy5 native crystal form
    29% identity, 80% coverage of query (79.0 bits)

8hplC / A0R2C0 Lpqy-sugabc in state 1 (see paper)
    27% identity, 80% coverage of query (79.0 bits)

8hprC Lpqy-sugabc in state 4
    27% identity, 80% coverage of query (78.6 bits)

8hprD Lpqy-sugabc in state 4
    27% identity, 80% coverage of query (78.6 bits)

6xjiC / X5EJW5 Pmtcd abc exporter at c1 symmetry (see paper)
    26% identity, 81% coverage of query (78.2 bits)

6xjhC Pmtcd abc exporter without the basket domain at c2 symmetry
    26% identity, 81% coverage of query (77.8 bits)

P9WQK5 Uncharacterized ABC transporter ATP-binding protein Rv0073 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv)
    27% identity, 79% coverage of query (75.9 bits)

6z67B Ftse structure of streptococcus pneumoniae in complex with amppnp at 2.4 a resolution
    26% identity, 78% coverage of query (75.9 bits)

6z4wA / Q8DQH4 Ftse structure from streptococcus pneumoniae in complex with adp (space group p 1) (see paper)
    26% identity, 78% coverage of query (75.9 bits)

1g291 / Q9YGA6 Malk (see paper)
    25% identity, 82% coverage of query (75.5 bits)

ECFA2_STRT2 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA2; ECF transporter A component EcfA2; EC 3.6.3.- from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311) (see paper)
TC 3.A.1.25.6 / Q5M244 Energy-coupling factor transporter ATP-binding protein EcfA 1, component of Riboflavin ECF transport system, EcfAA'T/RibU from Streptococcus thermophilus (strain ATCC BAA-250 / LMG 18311)
    28% identity, 81% coverage of query (75.5 bits)

2d62A / O57933 Crystal structure of multiple sugar binding transport atp- binding protein
    25% identity, 82% coverage of query (75.1 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory