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Searching for up to 100 curated homologs for AZOBR_RS08655 FitnessBrowser__azobra:AZOBR_RS08655 (340 a.a.)

Found high-coverage hits (≥70%) to 19 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

SMc02118 ABC transporter for L-Glutamine, L-Histidine, and other L-amino acids, periplasmic substrate-binding component from Sinorhizobium meliloti 1021
    64% identity, 100% coverage of query (462 bits)

AAPJ_RHIJ3 / Q52812 General L-amino acid-binding periplasmic protein AapJ from Rhizobium johnstonii (strain DSM 114642 / LMG 32736 / 3841) (Rhizobium leguminosarum bv. viciae) (see 2 papers)
TC 3.A.1.3.8 / Q52812 AapJ, component of General L-amino acid porter; transports basic and acidic amino acids preferentially, but also transports aliphatic amino acids (catalyzes both uptake and efflux) from Rhizobium leguminosarum (biovar viciae) (see 2 papers)
aapJ / CAA57933.1 general amino acid ABC type transporter from Rhizobium leguminosarum (see paper)
    65% identity, 100% coverage of query (458 bits)

4z9nB / A0A0M3KL33 Abc transporter / periplasmic binding protein from brucella ovis with glutathione bound
    62% identity, 93% coverage of query (414 bits)

Pf6N2E2_5402 ABC transporter for D-Alanine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E2
    57% identity, 99% coverage of query (405 bits)

TC 3.A.1.3.7 / Q52663 BztA, component of Glutamate/glutamine/aspartate/asparagine porter from Rhodobacter capsulatus (Rhodopseudomonas capsulata) (see paper)
    58% identity, 93% coverage of query (355 bits)

TC 3.A.1.3.18 / Q8YPM9 NatF, component of Acidic and neutral amino acid uptake transporter NatFGH/BgtA. BgtA is shared with BgtAB (see paper)
    50% identity, 95% coverage of query (336 bits)

cjaA / CAJ20048.1 glutamine-binding protein from Campylobacter jejuni (see paper)
    31% identity, 70% coverage of query (87.8 bits)

Build an alignment

Build an alignment for AZOBR_RS08655 and 7 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Additional hits (identity < 30%)

2ia4B / A0A0H2UXX1 Crystal structure of novel amino acid binding protein from shigella flexneri
    26% identity, 73% coverage of query (72.0 bits)

TC 3.A.1.3.16 / Q0P9X8 PEB1A, component of Uptake system for glutamate and aspartate from Campylobacter jejuni (see 2 papers)
peb1A / RF|YP_002344319.1 major cell-binding factor from Campylobacter jejuni (see 3 papers)
peb1 / AAA02919.1 major cell-binding factor from Campylobacter jejuni (see paper)
    25% identity, 78% coverage of query (71.6 bits)

2vhaA Debp
    26% identity, 73% coverage of query (71.6 bits)

2v25A / Q0P9X8 Structure of the campylobacter jejuni antigen peb1a, an aspartate and glutamate receptor with bound aspartate (see paper)
    25% identity, 73% coverage of query (70.5 bits)

AO356_00480 ABC transporter for D-Glucosamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2C3
    25% identity, 81% coverage of query (68.9 bits)

8ovoA / P37902,P42212 X-ray structure of the sf-iglusnfr-s72a in complex with l-aspartate
    26% identity, 73% coverage of query (68.6 bits)

GltI / b0655 glutamate/aspartate ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
GltI / P37902 glutamate/aspartate ABC transporter periplasmic binding protein (EC 7.4.2.1) from Escherichia coli (strain K12) (see 3 papers)
GLTI_ECOLI / P37902 Glutamate/aspartate import solute-binding protein from Escherichia coli (strain K12) (see 3 papers)
TC 3.A.1.3.4 / P37902 YBEJ aka GltI aka B0655, component of Glutamate/aspartate porter from Escherichia coli (see 6 papers)
gltI / GB|BAA35307.2 glutamate-aspartate periplasmic-binding protein from Escherichia coli K12 (see 6 papers)
    26% identity, 73% coverage of query (67.0 bits)

AO353_16290 ABC transporter for L-aspartate, L-asparagine, L-glutamate, and L-glutamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
    28% identity, 73% coverage of query (66.2 bits)

AO353_21710 ABC transporter for D-glucosamine, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N2E3
    27% identity, 71% coverage of query (64.7 bits)

Pf1N1B4_771 ABC transporter for L-asparagine and L-glutamate, periplasmic substrate-binding component from Pseudomonas fluorescens FW300-N1B4
    28% identity, 70% coverage of query (63.2 bits)

GASBP_PSEAE / Q9I402 L-glutamate/L-aspartate-binding protein from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see paper)
TC 3.A.1.3.22 / Q9I402 Probable binding protein component of ABC transporter, component of Amino acid transporter, AatJMQP. Probably transports L-glutamic acid, D-glutamine acid, L-glutamine and N-acetyl L-glutamic acid (Johnson et al. 2008). Very similar to 3.A.1.3.19 of P. putida from Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
    26% identity, 73% coverage of query (56.2 bits)

PfGW456L13_4770 ABC transporter for L-Asparagine and possibly other L-amino acids, periplasmic substrate-binding component from Pseudomonas fluorescens GW456-L13
    28% identity, 70% coverage of query (55.1 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory