Searching for up to 100 curated homologs for AZOBR_RS11025 FitnessBrowser__azobra:AZOBR_RS11025 (481 a.a.)
Found high-coverage hits (≥70%) to 36 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
P33197 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Thermus thermophilus (see 2 papers)
icd / RF|YP_144801.1 isocitrate dehydrogenase (NADP(+)); EC 1.1.1.42 from Thermus thermophilus HB8 (see 2 papers)
44% identity, 98% coverage of query (353 bits)
2d1cA / P33197 Crystal structure of tt0538 protein from thermus thermophilus hb8
44% identity, 98% coverage of query (353 bits)
6lkyA / Q602J2 Crystal structure of isocitrate dehydrogenase from methylococcus capsulatus
48% identity, 70% coverage of query (286 bits)
6m3sB / A0A0H2XBX7 Dimeric isocitrate dehydrogenase from xanthomonas campestris pv. Campestris 8004
47% identity, 70% coverage of query (263 bits)
G1APK3 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Rhodotorula toruloides (see paper)
43% identity, 70% coverage of query (251 bits)
3blvC / P28834 Yeast isocitrate dehydrogenase with citrate bound in the regulatory subunits (see paper)
37% identity, 70% coverage of query (211 bits)
IDH1 / P28834 isocitrate dehydrogenase [NAD] α subunit (EC 1.1.1.286) from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (see paper)
IDH1_YEAST / P28834 Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see paper)
P28834 isocitrate dehydrogenase (NAD+) (EC 1.1.1.41) from Saccharomyces cerevisiae (see paper)
36% identity, 70% coverage of query (210 bits)
3blwA Yeast isocitrate dehydrogenase with citrate and amp bound in the regulatory subunits
37% identity, 70% coverage of query (210 bits)
3asjA / Q5SIJ1 Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor (see paper)
40% identity, 70% coverage of query (203 bits)
hicdh / Q5SIJ1 homoisocitrate dehydrogenase subunit (EC 1.1.1.87) from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET8 / Q5SIJ1 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC 27634 / DSM 579 / HB8) (see paper)
HICDH_THET2 / Q72IW9 Isocitrate/homoisocitrate dehydrogenase; Homoisocitrate dehydrogenase; HICDH; EC 1.1.1.286 from Thermus thermophilus (strain ATCC BAA-163 / DSM 7039 / HB27) (see 4 papers)
Q5SIJ1 homoisocitrate dehydrogenase (EC 1.1.1.87) from Thermus thermophilus (see paper)
40% identity, 70% coverage of query (203 bits)
4yb4A Crystal structure of homoisocitrate dehydrogenase from thermus thermophilus in complex with homoisocitrate, magnesium ion (ii) and nadh
40% identity, 70% coverage of query (203 bits)
3asjB Crystal structure of homoisocitrate dehydrogenase in complex with a designed inhibitor
40% identity, 70% coverage of query (203 bits)
2iv0A / O29610 Thermal stability of isocitrate dehydrogenase from archaeoglobus fulgidus studied by crystal structure analysis and engineering of chimers (see paper)
37% identity, 70% coverage of query (195 bits)
IDH1_SCHPO / O13696 Isocitrate dehydrogenase [NAD] subunit 1, mitochondrial; Isocitric dehydrogenase; NAD(+)-specific ICDH; EC 1.1.1.41 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
idh1 / RF|NP_594397.1 isocitrate dehydrogenase (NAD+) subunit 1 Idh1; EC 1.1.1.41 from Schizosaccharomyces pombe (see 3 papers)
35% identity, 70% coverage of query (194 bits)
IcdE / b1136 isocitrate dehydrogenase (EC 1.1.1.42) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
icd / P08200 isocitrate dehydrogenase (EC 1.1.1.42) from Escherichia coli (strain K12) (see 3 papers)
IDH_ECOLI / P08200 Isocitrate dehydrogenase [NADP]; IDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Escherichia coli (strain K12) (see 7 papers)
P08200 [Isocitrate dehydrogenase (NADP+)] kinase (EC 2.7.11.5) from Escherichia coli (see paper)
4aj3A / P08200 3d structure of e. Coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and NADP - the pseudo-michaelis complex (see paper)
35% identity, 70% coverage of query (181 bits)
4ajaA 3d structure of e. Coli isocitrate dehydrogenase in complex with isocitrate, calcium(ii) and thionadp
35% identity, 70% coverage of query (181 bits)
1bl5A Isocitrate dehydrogenase from e. Coli single turnover laue structure of rate-limited product complex, 10 msec time resolution
35% identity, 70% coverage of query (181 bits)
1ai3A Orbital steering in the catalytic power of enzymes: small structural changes with large catalytic consequences
35% identity, 70% coverage of query (181 bits)
1ai2A Isocitrate dehydrogenase complexed with isocitrate, NADP+, and calcium (flash-cooled)
35% identity, 70% coverage of query (181 bits)
IDH_HALVD / D4GU92 Isocitrate dehydrogenase [NADP]; IDH; ICDH; IDP; NADP(+)-specific ICDH; Oxalosuccinate decarboxylase; EC 1.1.1.42 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
34% identity, 70% coverage of query (179 bits)
1isoA Isocitrate dehydrogenase: structure of an engineered NADP+--> NAD+ specificity-reversal mutant
35% identity, 70% coverage of query (179 bits)
1hj6A Isocitrate dehydrogenase s113e mutant complexed with isopropylmalate, NADP+ and magnesium (flash-cooled)
35% identity, 70% coverage of query (179 bits)
4ajcA 3d structure of e. Coli isocitrate dehydrogenase k100m mutant in complex with alpha-ketoglutarate, calcium(ii) and adenine nucleotide phosphate
35% identity, 70% coverage of query (178 bits)
1cw4A Crystal structure of k230m isocitrate dehydrogenase in complex with alpha-ketoglutarate
35% identity, 70% coverage of query (178 bits)
1cw1A Crystal structure of isocitrate dehydrogenase mutant k230m bound to isocitrate and mn2+
35% identity, 70% coverage of query (178 bits)
1idcA Isocitrate dehydrogenase from e.Coli (mutant k230m), steady-state intermediate complex determined by laue crystallography
35% identity, 70% coverage of query (178 bits)
D0Z8Y6 isocitrate dehydrogenase (NADP+) (EC 1.1.1.42) from Edwardsiella tarda (see paper)
35% identity, 70% coverage of query (176 bits)
icdh / CAC80860.2 NADP-isocitrate dehydrogenase from Haloferax volcanii (see paper)
33% identity, 70% coverage of query (176 bits)
1groA Regulatory and catalytic mechanisms in escherichia coli isocitrate dehydrogenase: multiple roles for n115
34% identity, 70% coverage of query (175 bits)
icd / Q5UXA4 isocitrate dehydrogenase, NADP (EC 1.1.1.42) from Haloarcula marismortui (strain ATCC 43049 / DSM 3752 / JCM 8966 / VKM B-1809) (see 4 papers)
33% identity, 71% coverage of query (173 bits)
LYS12_YEAST / P40495 Homoisocitrate dehydrogenase, mitochondrial; HIcDH; EC 1.1.1.87 from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 8 papers)
P40495 homoisocitrate dehydrogenase (EC 1.1.1.87) from Saccharomyces cerevisiae (see 2 papers)
35% identity, 71% coverage of query (158 bits)
LEU32_ARATH / P93832 3-isopropylmalate dehydrogenase 2, chloroplastic; 3-IPM-DH 2; AtIMDH2; AtIMDH3; IMDH 2; Beta-IPM dehydrogenase 2; Isopropylmalate dehydrogenase 2; AtIMD2; EC 1.1.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
P93832 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Arabidopsis thaliana (see 4 papers)
32% identity, 71% coverage of query (147 bits)
IMDH3 / Q9FMT1 isopropylmalate dehydrogenase 3 (EC 1.1.1.85) from Arabidopsis thaliana (see paper)
LEU31_ARATH / Q9FMT1 3-isopropylmalate dehydrogenase 1, chloroplastic; 3-IPM-DH 1; AtIMDH1; IMDH 1; Beta-IPM dehydrogenase 1; Isopropylmalate dehydrogenase 1; AtIMD1; Methylthioalkylmalate dehydrogenase 1; EC 1.1.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 5 papers)
Q9FMT1 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Arabidopsis thaliana (see 4 papers)
31% identity, 71% coverage of query (140 bits)
LEU33_ARATH / Q9SA14 3-isopropylmalate dehydrogenase 3, chloroplastic; 3-IPM-DH 3; AtIMDH2; AtIMDH3; IMDH 3; Beta-IPM dehydrogenase 3; Isopropylmalate dehydrogenase 3; AtIMD3; EC 1.1.1.85 from Arabidopsis thaliana (Mouse-ear cress) (see 4 papers)
Q9SA14 3-isopropylmalate dehydrogenase (EC 1.1.1.85) from Arabidopsis thaliana (see 3 papers)
31% identity, 71% coverage of query (139 bits)
3vmkA / D2YZL2 3-isopropylmalate dehydrogenase from shewanella benthica db21 mt-2 (see paper)
30% identity, 70% coverage of query (127 bits)
P18869 3-isopropylmalate dehydrogenase; 3-IPM-DH; IMDH; Beta-IPM dehydrogenase; EC 1.1.1.85 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast)
30% identity, 70% coverage of query (105 bits)
Build an alignment for AZOBR_RS11025 and 36 homologs with ≥ 30% identity
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Lawrence Berkeley National Laboratory