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Searching for up to 100 curated homologs for AZOBR_RS11740 FitnessBrowser__azobra:AZOBR_RS11740 (383 a.a.)

Found high-coverage hits (≥70%) to 31 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

XDH_PAENI / Q8GAK6 D-xylose dehydrogenase; NADP-dependent D-xylose dehydrogenase; EC 1.1.1.179 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see paper)
    60% identity, 98% coverage of query (468 bits)

Build an alignment

Build an alignment for AZOBR_RS11740 and 1 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

6a3jC / F0M433 Levoglucosan dehydrogenase, complex with nadh and l-sorbose (see paper)
    22% identity, 87% coverage of query (77.4 bits)

Asphe3_10730 / F0M433 levoglucosan dehydrogenase monomer (EC 1.1.1.425) from Pseudarthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3) (see 2 papers)
LGDH_PSEPM / F0M433 Levoglucosan dehydrogenase; LGDH; 1,6-anhydro-beta-D-glucose dehydrogenase; PpLGDH; EC 1.1.1.425 from Pseudarthrobacter phenanthrenivorans (strain DSM 18606 / JCM 16027 / LMG 23796 / Sphe3) (Arthrobacter phenanthrenivorans) (see paper)
F0M433 levoglucosan dehydrogenase (EC 1.1.1.425) from Pseudarthrobacter phenanthrenivorans (see paper)
    22% identity, 87% coverage of query (73.6 bits)

6a3iA Levoglucosan dehydrogenase, complex with nadh and levoglucosan
    22% identity, 87% coverage of query (73.2 bits)

1zh8A / Q9WYE8 Crystal structure of oxidoreductase (tm0312) from thermotoga maritima at 2.50 a resolution
    23% identity, 86% coverage of query (66.2 bits)

HSERO_RS12095 Myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Herbaspirillum seropedicae SmR1
    25% identity, 85% coverage of query (65.9 bits)

2o4uX / Q9TQS6 Crystal structure of mammalian dimeric dihydrodiol dehydrogenase (see paper)
    22% identity, 77% coverage of query (64.7 bits)

DHDH_MACFU / Q7JK39 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; Jmo2DD; EC 1.3.1.20; EC 1.1.1.179 from Macaca fuscata fuscata (Japanese macaque) (see 3 papers)
DHDH_MACFA / Q9TQS6 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; Cmo2DD; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; EC 1.3.1.20; EC 1.1.1.179 from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
Q9TQS6 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179); trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Macaca fascicularis (see 2 papers)
    22% identity, 77% coverage of query (64.7 bits)

2poqX Dimeric dihydrodiol dehydrogenase complexed with inhibitor, isoascorbic acid
    22% identity, 77% coverage of query (64.7 bits)

APSD_PARG4 / B1G894 D-apiose dehydrogenase; EC 1.1.1.420 from Paraburkholderia graminis (strain ATCC 700544 / DSM 17151 / LMG 18924 / NCIMB 13744 / C4D1M) (see paper)
    27% identity, 90% coverage of query (63.5 bits)

iolG / Q9WYP5 myo-inositol 2-dehydrogenase (EC 1.1.1.18) from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
IOLG_THEMA / Q9WYP5 Myo-inositol 2-dehydrogenase; EC 1.1.1.18 from Thermotoga maritima (strain ATCC 43589 / DSM 3109 / JCM 10099 / NBRC 100826 / MSB8) (see paper)
Q9WYP5 D-chiro-inositol 1-dehydrogenase (EC 1.1.1.369) from Thermotoga maritima (see paper)
    24% identity, 89% coverage of query (63.2 bits)

SM_b20330 glucoside 3-dehydrogenase; active on raffinose or trehalose (thuB) (EC 1.1.99.13) from Sinorhizobium meliloti 1021
    27% identity, 85% coverage of query (62.8 bits)

Q5R5J5 trans-1,2-dihydrobenzene-1,2-diol dehydrogenase (EC 1.3.1.20) from Pongo abelii (see paper)
    21% identity, 77% coverage of query (58.5 bits)

6jw7A / Q6L737 The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin a (see paper)
    25% identity, 83% coverage of query (57.4 bits)

6jw8A The crystal structure of kand2 in complex with nadh and 3"-deamino-3"- hydroxykanamycin b
    25% identity, 83% coverage of query (57.4 bits)

6jw6A The crystal structure of kand2 in complex with NAD
    25% identity, 83% coverage of query (57.0 bits)

5a03C / Q9A8X3 Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose (see paper)
    22% identity, 86% coverage of query (56.2 bits)

5a06A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with sorbitol
    22% identity, 86% coverage of query (56.2 bits)

5a05A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with maltotriose
    22% identity, 86% coverage of query (56.2 bits)

5a04A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glucose
    22% identity, 86% coverage of query (56.2 bits)

5a03E Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with xylose
    22% identity, 86% coverage of query (56.2 bits)

5a02A Crystal structure of aldose-aldose oxidoreductase from caulobacter crescentus complexed with glycerol
    22% identity, 86% coverage of query (56.2 bits)

iolW / O32223 scyllo-inositol dehydrogenase (NADP+) (EC 1.1.1.371) from Bacillus subtilis (strain 168) (see paper)
IOLW_BACSU / O32223 scyllo-inositol 2-dehydrogenase (NADP(+)) IolW; NADP(+)-dependent scyllo-inositol dehydrogenase 1; NADP(+)-dependent SI dehydrogenase 1; EC 1.1.1.371 from Bacillus subtilis (strain 168) (see 3 papers)
O32223 scyllo-inositol 2-dehydrogenase (NADP+) (EC 1.1.1.371) from Bacillus subtilis (see 2 papers)
    24% identity, 72% coverage of query (55.8 bits)

DHDH_HUMAN / Q9UQ10 Trans-1,2-dihydrobenzene-1,2-diol dehydrogenase; D-xylose 1-dehydrogenase; D-xylose-NADP dehydrogenase; Dimeric dihydrodiol dehydrogenase; Hum2DD; EC 1.3.1.20; EC 1.1.1.179 from Homo sapiens (Human) (see paper)
    21% identity, 77% coverage of query (55.5 bits)

6norA / Q70KD1 Crystal structure of gend2 from gentamicin a biosynthesis in complex with NAD (see paper)
    24% identity, 86% coverage of query (48.5 bits)

1evjA Crystal structure of glucose-fructose oxidoreductase (gfor) delta1-22 s64d
    22% identity, 86% coverage of query (48.5 bits)

apsD / B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium radiobacter (strain K84 / ATCC BAA-868) (see paper)
APSD_RHIR8 / B9JK80 D-apiose dehydrogenase; EC 1.1.1.420 from Rhizobium rhizogenes (strain K84 / ATCC BAA-868) (Agrobacterium radiobacter) (see paper)
B9JK80 D-apiose dehydrogenase (EC 1.1.1.420) from Agrobacterium tumefaciens (see paper)
    22% identity, 87% coverage of query (47.0 bits)

5uhwA / B9JK80 Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+ and magnesium
    22% identity, 87% coverage of query (46.6 bits)

5uiaA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, r-2,3-dihydroxyisovalerate and magnesium
    22% identity, 87% coverage of query (46.6 bits)

5ui9A Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, 2 -hydroxy-2-hydroxymethyl propanoic acid and magnesium
    22% identity, 87% coverage of query (46.6 bits)

5uhzA Crystal structure of an oxidoreductase from agrobacterium radiobacter in complex with NAD+, d-apionate and magnesium
    22% identity, 87% coverage of query (46.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory