Searching for up to 100 curated homologs for AZOBR_RS16920 FitnessBrowser__azobra:AZOBR_RS16920 (292 a.a.)
Found high-coverage hits (≥70%) to 81 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
HBD_BACSU / P45856 Probable 3-hydroxybutyryl-CoA dehydrogenase; Beta-hydroxybutyryl-CoA dehydrogenase; BHBD; EC 1.1.1.157 from Bacillus subtilis (strain 168) (see paper)
mmgB / GI|881605 3-hydroxybutyryl-CoA dehydrogenase from Bacillus subtilis (see paper)
55% identity, 97% coverage of query (327 bits)
hbd / P52041 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.35) from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / LMG 5710 / VKM B-1787) (see 2 papers)
HBD_CLOAB / P52041 3-hydroxybutyryl-CoA dehydrogenase; Beta-hydroxybutyryl-CoA dehydrogenase; BHBD; EC 1.1.1.157 from Clostridium acetobutylicum (strain ATCC 824 / DSM 792 / JCM 1419 / IAM 19013 / LMG 5710 / NBRC 13948 / NRRL B-527 / VKM B-1787 / 2291 / W) (see paper)
hbd 3-hydroxybutyryl-CoA dehydrogenase; EC 1.1.1.157 from Clostridium acetobutylicum (see paper)
56% identity, 97% coverage of query (326 bits)
hbd / Q8RMI3 3-hydroxybutyryl-CoA dehydrogenase subunit (EC 1.1.1.35) from Clostridium beijerinckii (see 3 papers)
54% identity, 97% coverage of query (326 bits)
6aa8E / P52041 Crystal structure of (s)-3-hydroxybutyryl-coenzymea dehydrogenase from clostridium acetobutylicum complexed with NAD+ (see paper)
56% identity, 96% coverage of query (326 bits)
C4IEM5 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Clostridium butyricum (see 2 papers)
4kugA / C4IEM5 Crystal structure of 3-hydroxybutylryl-coa dehydrogenase with NAD from clostridium butyricum
54% identity, 97% coverage of query (319 bits)
4kuhA Crystal structure of 3-hydroxybutylryl-coa dehydrogenase with acetoacetyl-coa from clostridium butyricum
53% identity, 96% coverage of query (316 bits)
A0A0E3GR61 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157) from Clostridium scatologenes (see paper)
53% identity, 96% coverage of query (312 bits)
HBD_SYNWW / Q0AVM2 3-hydroxybutyryl-CoA dehydrogenase; EC 1.1.1.35 from Syntrophomonas wolfei subsp. wolfei (strain DSM 2245B / Goettingen) (see paper)
50% identity, 95% coverage of query (298 bits)
Q0KEY8 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Cupriavidus necator (see 2 papers)
53% identity, 97% coverage of query (297 bits)
4pzdA / Q0KEY8 Crystal structure of (s)-3-hydroxybutyryl-coa dehydrogenase paah1 in complex with NAD+ (see paper)
53% identity, 97% coverage of query (296 bits)
4pzeA Crystal structure of (s)-3-hydroxybutyryl-coa dehydrogenase paah1 in complex with acetoacetyl-coa
53% identity, 97% coverage of query (296 bits)
mdpX / A2SP28 (S)-3-hydroxybutanoyl-CoA dehydrogeanse (EC 1.1.1.35) from Methylibium petroleiphilum (strain ATCC BAA-1232 / LMG 22953 / PM1) (see 2 papers)
50% identity, 95% coverage of query (286 bits)
gdnD / K4JH65 L-seryl-[seryl-carrier protein] dehydrogenase from Streptomyces sp. K01-0509 (see 2 papers)
44% identity, 97% coverage of query (236 bits)
FADB2_MYCTU / P9WNP7 3-hydroxybutyryl-CoA dehydrogenase; Beta-hydroxybutyryl-CoA dehydrogenase; BHBD; EC 1.1.1.157 from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 3 papers)
P9WNP7 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Mycobacterium tuberculosis (see paper)
41% identity, 96% coverage of query (234 bits)
Tfu_2399 / Q47M90 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Thermobifida fusca (strain YX) (see 3 papers)
41% identity, 99% coverage of query (225 bits)
P34439 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Caenorhabditis elegans (see 2 papers)
41% identity, 98% coverage of query (223 bits)
1f12A / Q16836 L-3-hydroxyacyl-coa dehydrogenase complexed with 3-hydroxybutyryl-coa (see paper)
41% identity, 96% coverage of query (216 bits)
HADH / Q16836 short-chain 3-hydroxyacyl-CoA dehydrogenase monomer (EC 1.1.1.35) from Homo sapiens (see 12 papers)
HCDH_HUMAN / Q16836 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; HCDH; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35 from Homo sapiens (Human) (see 5 papers)
41% identity, 96% coverage of query (216 bits)
1f0yA L-3-hydroxyacyl-coa dehydrogenase complexed with acetoacetyl-coa and NAD+
41% identity, 96% coverage of query (216 bits)
1f17A L-3-hydroxyacyl-coa dehydrogenase complexed with nadh
41% identity, 96% coverage of query (216 bits)
HCDH_PIG / P00348 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; HCDH; L-3-hydroxyacyl CoA dehydrogenase; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35 from Sus scrofa (Pig) (see 3 papers)
40% identity, 96% coverage of query (212 bits)
HCDH_MOUSE / Q61425 Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial; HCDH; Medium and short-chain L-3-hydroxyacyl-coenzyme A dehydrogenase; Short-chain 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35 from Mus musculus (Mouse) (see 2 papers)
40% identity, 96% coverage of query (210 bits)
D3RXI4 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) from Ferroglobus placidus (see paper)
39% identity, 99% coverage of query (209 bits)
YdbU / b1395 3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) from Escherichia coli K-12 substr. MG1655 (see 3 papers)
paaH / P76083 3-hydroxyadipyl-CoA dehydrogenase (EC 1.1.1.35) from Escherichia coli (strain K12) (see 3 papers)
PAAH_ECOLI / P76083 3-hydroxyadipyl-CoA dehydrogenase; EC 1.1.1.- from Escherichia coli (strain K12) (see 4 papers)
39% identity, 97% coverage of query (206 bits)
clbD / Q0P7J4 L-seryl-[peptidyl-carrier protein] 3-dehydrogenase ClbD from Escherichia coli (see paper)
40% identity, 96% coverage of query (205 bits)
paaH2 / Q0KCM8 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35) from Cupriavidus necator (strain ATCC 17699 / DSM 428 / KCTC 22496 / NCIMB 10442 / H16 / Stanier 337) (see paper)
37% identity, 97% coverage of query (194 bits)
zmaG / Q7BQ74 D-glyceryl/L-seryl-[acp] dehydrogenase from Bacillus cereus (see 2 papers)
38% identity, 96% coverage of query (192 bits)
HP15_2693 3-hydroxyacyl-CoA dehydrogenase PaaC (EC 1.1.1.-) from Marinobacter adhaerens HP15
36% identity, 99% coverage of query (187 bits)
dcaH / AAL09091.1 DcaH from Acinetobacter baylyi (see 11 papers)
37% identity, 96% coverage of query (185 bits)
8oqsB / O53872 Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-83
37% identity, 96% coverage of query (179 bits)
8oqqA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-79
37% identity, 96% coverage of query (179 bits)
8oqpA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-76
37% identity, 96% coverage of query (179 bits)
8oqvA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-109
37% identity, 96% coverage of query (179 bits)
8oqoA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-49
37% identity, 96% coverage of query (179 bits)
4b3iA Crystal structure of mycobacterium tuberculosis fatty acid beta- oxidation complex with coenzymea bound at the hydratase active sites
37% identity, 96% coverage of query (179 bits)
8oqlA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-1
37% identity, 96% coverage of query (179 bits)
8pf8A Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-72
37% identity, 96% coverage of query (179 bits)
8oquA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-92
37% identity, 96% coverage of query (179 bits)
8oqtA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-91
37% identity, 96% coverage of query (179 bits)
8oqnA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-53
37% identity, 96% coverage of query (179 bits)
8opvA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with resveratrol (fragment-b-h11)
37% identity, 96% coverage of query (179 bits)
8opuA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with sulfamethoxazole (fragment-b-e1)
37% identity, 96% coverage of query (179 bits)
8oqrA Structure of mycobacterium tuberculosis beta-oxidation trifunctional enzyme in complex with fragment-m-80
37% identity, 96% coverage of query (179 bits)
7o4uA Structure of the alpha subunit of mycobacterium tuberculosis beta- oxidation trifunctional enzyme in complex with oxidized nicotinamide adenine dinucleotide
37% identity, 96% coverage of query (179 bits)
Msed_0399 / A4YDS4 crotonyl-CoA hydratase/(S)-3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.35; EC 4.2.1.150) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see 3 papers)
A4YDS4 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); short-chain-enoyl-CoA hydratase (EC 4.2.1.150) from Metallosphaera sedula (see 2 papers)
37% identity, 95% coverage of query (178 bits)
Q88L88 long-chain-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211) from Pseudomonas putida (see paper)
37% identity, 96% coverage of query (178 bits)
fkbK / Q9KIE3 D-glyceryl-[acp] dehydrogenase from Streptomyces hygroscopicus subsp. ascomyceticus (see 3 papers)
39% identity, 95% coverage of query (171 bits)
6iunB / Q0KBG3 Crystal structure of enoyl-coa hydratase (ech) from ralstonia eutropha h16 in complex with NAD
33% identity, 99% coverage of query (151 bits)
fadB / Q9HZJ2 fatty acid oxidation complex α subunit (EC 1.1.1.35; EC 4.2.1.74) from Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C / PRS 101 / PAO1) (see 2 papers)
36% identity, 91% coverage of query (151 bits)
HADHA / P40939 mitochondrial trifunctional enzyme α subunit (EC 1.1.1.35; EC 4.2.1.17; EC 1.1.1.211) from Homo sapiens (see 5 papers)
ECHA_HUMAN / P40939 Trifunctional enzyme subunit alpha, mitochondrial; 78 kDa gastrin-binding protein; Monolysocardiolipin acyltransferase; TP-alpha; EC 2.3.1.-; EC 4.2.1.17; EC 1.1.1.211 from Homo sapiens (Human) (see 11 papers)
P40939 long-chain-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211) from Homo sapiens (see 6 papers)
32% identity, 97% coverage of query (150 bits)
asm13 / Q8KUG1 D-glyceryl-[acp] 3-dehydrogenase from Actinosynnema pretiosum subsp. auranticum (see 4 papers)
33% identity, 95% coverage of query (150 bits)
ECHA_RAT / Q64428 Trifunctional enzyme subunit alpha, mitochondrial; Monolysocardiolipin acyltransferase; TP-alpha; EC 2.3.1.-; EC 4.2.1.17; EC 1.1.1.211 from Rattus norvegicus (Rat) (see paper)
Q64428 long-chain-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.211); acetyl-CoA C-acyltransferase (EC 2.3.1.16) from Rattus norvegicus (see 6 papers)
34% identity, 97% coverage of query (149 bits)
HP15_1512 Enoyl-CoA hydratase (EC 4.2.1.17) from Marinobacter adhaerens HP15
32% identity, 95% coverage of query (148 bits)
MFPA_CUCSA / Q39659 Glyoxysomal fatty acid beta-oxidation multifunctional protein MFP-a; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Cucumis sativus (Cucumber) (see paper)
32% identity, 97% coverage of query (147 bits)
fadB / Q88L02 FadB (EC 5.3.3.8; EC 1.1.1.35; EC 5.1.2.3; EC 4.2.1.17; EC 1.1.1.36) from Pseudomonas putida (strain ATCC 47054 / DSM 6125 / CFBP 8728 / NCIMB 11950 / KT2440) (see 3 papers)
35% identity, 91% coverage of query (147 bits)
ECHA_MOUSE / Q8BMS1 Trifunctional enzyme subunit alpha, mitochondrial; Monolysocardiolipin acyltransferase; TP-alpha; EC 2.3.1.-; EC 4.2.1.17; EC 1.1.1.211 from Mus musculus (Mouse) (see paper)
34% identity, 97% coverage of query (146 bits)
FadJ / b2341 3-hydroxyacyl-CoA dehydrogenase FadJ (EC 1.1.1.35; EC 1.1.1.211; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8) from Escherichia coli K-12 substr. MG1655 (see 8 papers)
fadJ / P77399 multifunctional 3-hydroxyacyl-CoA dehydrogenase/3-hydroxyacyl-CoA epimerase/enoyl-CoA hydratase FadJ (EC 1.1.1.35; EC 4.2.1.17; EC 4.2.1.74; EC 5.1.2.3; EC 5.3.3.8) from Escherichia coli (strain K12) (see 6 papers)
FADJ_ECOLI / P77399 Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 1.1.1.35 from Escherichia coli (strain K12) (see 2 papers)
fadJ / RF|NP_416843 fatty acid oxidation complex subunit alpha; EC 1.1.1.35; EC 4.2.1.17; EC 5.1.2.3 from Escherichia coli K12 (see 8 papers)
34% identity, 91% coverage of query (146 bits)
6yswA / P77399 E. Coli anaerobic trifunctional enzyme subunit-alpha in complex with coenzyme a
34% identity, 91% coverage of query (146 bits)
1wdmA Fatty acid beta-oxidation multienzyme complex from pseudomonas fragi, form i (native3)
34% identity, 91% coverage of query (142 bits)
6tnmA / P21177 E. Coli aerobic trifunctional enzyme subunit-alpha (see paper)
33% identity, 98% coverage of query (142 bits)
OldB / b3846 multifunctional enoyl-CoA hydratase, 3-hydroxyacyl-CoA epimerase, Δ3-cis- Δ2-trans-enoyl-CoA isomerase, L-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35; EC 1.1.1.211; EC 4.2.1.17; EC 5.3.3.8; EC 5.1.2.3) from Escherichia coli K-12 substr. MG1655 (see 36 papers)
fadB / P21177 multifunctional enoyl-CoA hydratase, 3-hydroxyacyl-CoA epimerase, Δ3-cis- Δ2-trans-enoyl-CoA isomerase, L-3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35; EC 4.2.1.17; EC 4.2.1.74; EC 5.3.3.8; EC 5.1.2.3) from Escherichia coli (strain K12) (see 36 papers)
FADB_ECOLI / P21177 Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Escherichia coli (strain K12) (see 5 papers)
33% identity, 98% coverage of query (142 bits)
FADB_PSEFR / P28793 Fatty acid oxidation complex subunit alpha; EC 4.2.1.17; EC 5.1.2.3; EC 5.3.3.8; EC 1.1.1.35 from Pseudomonas fragi (see 2 papers)
1wdlA / P28793 Fatty acid beta-oxidation multienzyme complex from pseudomonas fragi, form ii (native4) (see paper)
34% identity, 91% coverage of query (141 bits)
3zwbA Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with 2trans-hexenoyl-coa
30% identity, 97% coverage of query (137 bits)
5omoA Crystal structure of rat peroxisomal multifunctional enzyme type-1 (rpmfe1) complexed with with 3s-hydroxy-decanoyl-coa and 3-keto- decanoyl-coa
30% identity, 97% coverage of query (136 bits)
5mgbA Crystal structure of rat peroxisomal multifunctional enzyme type-1 (rpmfe1) complexed with acetoacetyl-coa and NAD
30% identity, 97% coverage of query (136 bits)
3zwcA Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with 3s-hydroxy-decanoyl-coa
30% identity, 97% coverage of query (136 bits)
2x58A The crystal structure of mfe1 liganded with coa
30% identity, 97% coverage of query (136 bits)
3zwaA / P07896 Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with 3s-hydroxy-hexanoyl-coa (see paper)
30% identity, 97% coverage of query (136 bits)
3zw9A Crystal structure of rat peroxisomal multifunctional enzyme type 1 (rpmfe1) complexed with (2s,3s)-3-hydroxy-2-methylbutanoyl-coa
30% identity, 97% coverage of query (136 bits)
6zicAAA structure of rat peroxisomal multifunctional enzyme type-1 (rpmfe1) complexed with 3s-hydroxybutanoyl-coa and nadh'
30% identity, 97% coverage of query (135 bits)
6zibAAA structure of rat peroxisomal multifunctional enzyme type-1 (rpmfe1) complexed with acetoacetyl-coa and nadh'
30% identity, 97% coverage of query (134 bits)
Build an alignment for AZOBR_RS16920 and 71 homologs with ≥ 30% identity
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6z5oAAA Peroxisomal bifunctional enzyme
29% identity, 97% coverage of query (134 bits)
EHHADH / Q08426 peroxisomal bifunctional enzyme (EC 4.2.1.17; EC 1.1.1.35) from Homo sapiens (see 14 papers)
ECHP_HUMAN / Q08426 Peroxisomal bifunctional enzyme; PBE; PBFE; L-bifunctional protein; LBP; Multifunctional enzyme 1; MFE1; EC 4.2.1.17; EC 5.3.3.8; EC 1.1.1.35 from Homo sapiens (Human) (see 4 papers)
30% identity, 97% coverage of query (131 bits)
mlr6793 / Q988C8 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylate 5-dehydrogenase monomer (EC 1.2.1.100) from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (see 3 papers)
FHMCD_RHILO / Q988C8 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylate 5-dehydrogenase; FHMPC dehydrogenase; EC 1.2.1.100 from Mesorhizobium japonicum (strain LMG 29417 / CECT 9101 / MAFF 303099) (Mesorhizobium loti (strain MAFF 303099)) (see 2 papers)
Q988C8 4-pyridoxic acid dehydrogenase (EC 1.1.99.42); 5-formyl-3-hydroxy-2-methylpyridine 4-carboxylic acid 5-dehydrogenase (EC 1.2.1.100) from Mesorhizobium japonicum (see paper)
4om8A / Q988C8 Crystal structure of 5-formly-3-hydroxy-2-methylpyridine 4-carboxylic acid (fhmpc) 5-dehydrogenase, an NAD+ dependent dismutase. (see paper)
29% identity, 96% coverage of query (123 bits)
4dydA / B1P3E1 Substrate-directed dual catalysis of dicarbonyl compounds by diketoreductase (see paper)
29% identity, 97% coverage of query (122 bits)
3k6jA / O17762 Crystal structure of the dehydrogenase part of multifuctional enzyme 1 from c.Elegans
26% identity, 96% coverage of query (107 bits)
LCDH_PSESP / D7URM0 L-carnitine dehydrogenase; CDH; L-CDH; EC 1.1.1.108 from Pseudomonas sp. (see paper)
28% identity, 77% coverage of query (82.4 bits)
3f3sA / Q9Y2S2 The crystal structure of human lambda-crystallin, cryl1
25% identity, 76% coverage of query (62.8 bits)
CRYL1_HUMAN / Q9Y2S2 Lambda-crystallin homolog; L-gulonate 3-dehydrogenase; Gul3DH; EC 1.1.1.45 from Homo sapiens (Human) (see 2 papers)
25% identity, 76% coverage of query (62.8 bits)
3adpA / P14755 Crystal structure of the rabbit l-gulonate 3-dehydrogenase (nadh form)
26% identity, 76% coverage of query (58.9 bits)
CRYL1_RABIT / P14755 Lambda-crystallin; L-gulonate 3-dehydrogenase; Gul3DH; EC 1.1.1.45 from Oryctolagus cuniculus (Rabbit) (see paper)
P14755 L-gulonate 3-dehydrogenase (EC 1.1.1.45) from Oryctolagus cuniculus (see paper)
26% identity, 76% coverage of query (58.9 bits)
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Lawrence Berkeley National Laboratory