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Searching for up to 100 curated homologs for AZOBR_RS18740 FitnessBrowser__azobra:AZOBR_RS18740 (427 a.a.)

Found high-coverage hits (≥70%) to 30 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

7uoiA / A0A1S8KJG1 Crystallographic structure of dape from enterococcus faecium
    30% identity, 96% coverage of query (152 bits)

Q92Y75 acetylornithine deacetylase (EC 3.5.1.16) from Sinorhizobium meliloti (see paper)
    33% identity, 89% coverage of query (123 bits)

Build an alignment

Build an alignment for AZOBR_RS18740 and 2 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

5vo3A / P44514 Crystal structure of dape in complex with the products (succinic acid and diaminopimelic acid) (see paper)
    25% identity, 96% coverage of query (119 bits)

dapE / P44514 N-succinyl-L,L-diaminopimelate desuccinylase subunit (EC 3.5.1.18) from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see paper)
DAPE_HAEIN / P44514 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd) (see 7 papers)
P44514 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Haemophilus influenzae (see 3 papers)
    25% identity, 95% coverage of query (118 bits)

FAPD_BACSU / O31724 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase; Formylaminopyrimidine deformylase; Amidohydrolase YlmB; EC 3.5.1.- from Bacillus subtilis (strain 168) (see paper)
    27% identity, 98% coverage of query (114 bits)

DAPE_NEIMB / Q9JYL2 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Neisseria meningitidis serogroup B (strain MC58) (see paper)
Q9JYL2 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Neisseria meningitidis (see paper)
    27% identity, 91% coverage of query (107 bits)

4o23A / Q9JYL2 Crystal structure of mono-zinc form of succinyl diaminopimelate desuccinylase from neisseria meningitidis mc58 (see paper)
    27% identity, 91% coverage of query (106 bits)

4pqaA Crystal structure of succinyl-diaminopimelate desuccinylase from neisseria meningitidis mc58 in complex with the inhibitor captopril
    27% identity, 91% coverage of query (106 bits)

7t1qA / A3M8H2 Crystal structure of the succinyl-diaminopimelate desuccinylase (dape) from acinetobacter baumannii in complex with succinic acid
    28% identity, 89% coverage of query (105 bits)

7lgpB / P0AED8 Dape enzyme from shigella flexneri
    26% identity, 91% coverage of query (101 bits)

MsgB / b2472 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Escherichia coli K-12 substr. MG1655 (see 4 papers)
dapE / P0AED7 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Escherichia coli (strain K12) (see paper)
DAPE_ECOLI / P0AED7 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Escherichia coli (strain K12) (see paper)
dapE / RF|NP_416967 succinyl-diaminopimelate desuccinylase; EC 3.5.1.18 from Escherichia coli K12 (see 7 papers)
    26% identity, 91% coverage of query (101 bits)

YgeY / b2872 putative peptidase YgeY from Escherichia coli K-12 substr. MG1655 (see 3 papers)
    29% identity, 79% coverage of query (95.1 bits)

dapE / CAA08876.1 DapE from Bordetella pertussis (see paper)
    29% identity, 86% coverage of query (94.7 bits)

ylmB / Q9K9G9 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase from Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (see paper)
FAPD_HALH5 / Q9K9G9 N-formyl-4-amino-5-aminomethyl-2-methylpyrimidine deformylase; Formylaminopyrimidine deformylase; Amidohydrolase YlmB; EC 3.5.1.- from Halalkalibacterium halodurans (strain ATCC BAA-125 / DSM 18197 / FERM 7344 / JCM 9153 / C-125) (Bacillus halodurans) (see paper)
    25% identity, 96% coverage of query (94.0 bits)

DAPE_SALTY / Q8ZN75 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; Aspartyl peptidase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) (see paper)
    26% identity, 91% coverage of query (94.0 bits)

DAPE_VIBCH / Q9KQ52 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Vibrio cholerae serotype O1 (strain ATCC 39315 / El Tor Inaba N16961)
Q9KQ52 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Vibrio cholerae (see paper)
    27% identity, 91% coverage of query (90.5 bits)

C9K2Z6 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Streptomyces mobaraensis (see paper)
    27% identity, 78% coverage of query (85.5 bits)

argE / CAB95019.1 acetylornithinase (n2-acetyl-l-ornithine amidohydrolase) from Moritella abyssi (see paper)
    29% identity, 73% coverage of query (84.0 bits)

G8EJ32 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Heliothis virescens (see paper)
    25% identity, 74% coverage of query (80.1 bits)

A0A219YQV4 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Helicoverpa assulta (see paper)
    24% identity, 74% coverage of query (78.6 bits)

ArgE / b3957 acetylornithine deacetylase (EC 3.5.1.16) from Escherichia coli K-12 substr. MG1655 (see 6 papers)
argE / P23908 acetylornithine deacetylase (EC 3.5.1.16) from Escherichia coli (strain K12) (see 5 papers)
ARGE_ECOLI / P23908 Acetylornithine deacetylase; AO; Acetylornithinase; N-acetylornithinase; NAO; EC 3.5.1.16 from Escherichia coli (strain K12) (see 2 papers)
    27% identity, 90% coverage of query (78.2 bits)

7rsfA / P23908 Acetylornithine deacetylase from escherichia coli
    27% identity, 90% coverage of query (77.8 bits)

G8EJ34 N-acyl-aliphatic-L-amino acid amidohydrolase (EC 3.5.1.14) from Helicoverpa armigera (see paper)
    24% identity, 74% coverage of query (75.5 bits)

Echvi_3851 N-succinylcitrulline desuccinylase (EC 3.5.1.-) from Echinicola vietnamensis KMM 6221, DSM 17526
    25% identity, 82% coverage of query (74.7 bits)

DAPE_HELPY / O25002 Succinyl-diaminopimelate desuccinylase; SDAP desuccinylase; N-succinyl-LL-2,6-diaminoheptanedioate amidohydrolase; EC 3.5.1.18 from Helicobacter pylori (strain ATCC 700392 / 26695) (Campylobacter pylori) (see paper)
O25002 succinyl-diaminopimelate desuccinylase (EC 3.5.1.18) from Helicobacter pylori (see paper)
    26% identity, 74% coverage of query (74.3 bits)

N515DRAFT_3767 N-acetylcitrulline deacetylase (EC 3.5.1.-) from Dyella japonica UNC79MFTsu3.2
    25% identity, 93% coverage of query (64.7 bits)

lysK / Q4JAP7 [amino group carrier protein]-lysine/ornithine hydrolase (EC 3.5.1.130; EC 3.5.1.132) from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
    24% identity, 77% coverage of query (64.3 bits)

5k8pA Zn2+/tetrahedral intermediate-bound r289a 5-nitroanthranilate aminohydrolase
    24% identity, 82% coverage of query (52.4 bits)

5k8nA 5naa-bound 5-nitroanthranilate aminohydrolase
    24% identity, 82% coverage of query (52.0 bits)

naaA / D3WZ85 5-nitroanthranilate aminohydrolase (EC 3.5.99.8) from Bradyrhizobium sp. (see 2 papers)
NAAA_BRASZ / D3WZ85 5-nitroanthranilic acid aminohydrolase; 5-nitroanthranilic acid degradation protein A; 5NAA deaminase; EC 3.5.99.8 from Bradyrhizobium sp. (see 2 papers)
D3WZ85 5-nitroanthranilic acid aminohydrolase (EC 3.5.99.8) from Bradyrhizobium sp. (see 2 papers)
5k8oB / D3WZ85 Mn2+/5nsa-bound 5-nitroanthranilate aminohydrolase (see paper)
    24% identity, 82% coverage of query (51.6 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory