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Searching for up to 100 curated homologs for AZOBR_RS19085 FitnessBrowser__azobra:AZOBR_RS19085 (362 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

LOX_ALIDK / F4G5A4 L-lactate oxidase; LOX; Glycolate oxidase; EC 1.1.3.-; EC 1.1.3.15 from Alicycliphilus denitrificans (strain DSM 14773 / CIP 107495 / K601) (see paper)
    47% identity, 98% coverage of query (288 bits)

LOX_NOSS1 / Q8Z0C8 L-lactate oxidase; LOX; Glyoxylate oxidase; No-LOX; EC 1.1.3.-; EC 1.2.3.5 from Nostoc sp. (strain PCC 7120 / SAG 25.82 / UTEX 2576) (see 2 papers)
Q8Z0C8 L-lactate oxidase (EC 1.1.3.2) from Nostoc sp. PCC 7120 = FACHB-418 (see paper)
    47% identity, 98% coverage of query (263 bits)

Q7FAS1 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Oryza sativa Japonica Group (see paper)
    43% identity, 98% coverage of query (260 bits)

HAOX2_HUMAN / Q9NYQ3 2-Hydroxyacid oxidase 2; HAOX2; (S)-2-hydroxy-acid oxidase, peroxisomal; Cell growth-inhibiting gene 16 protein; Long chain alpha-hydroxy acid oxidase; Long-chain L-2-hydroxy acid oxidase; EC 1.1.3.15 from Homo sapiens (Human) (see paper)
Q9NYQ3 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Homo sapiens (see paper)
    40% identity, 96% coverage of query (251 bits)

GLO2_ARATH / Q9LRS0 Glycolate oxidase 2; AtGLO2; GOX2; (S)-2-hydroxy-acid oxidase GLO2; Short chain alpha-hydroxy acid oxidase GLO2; EC 1.1.3.15 from Arabidopsis thaliana (Mouse-ear cress) (see 2 papers)
    40% identity, 98% coverage of query (251 bits)

GLO1_ORYSJ / Q10CE4 Glycolate oxidase 1; GOX 1; OsGLO1; Peroxisomal (S)-2-hydroxy-acid oxidase GLO1; Short chain alpha-hydroxy acid oxidase GLO1; EC 1.1.3.15 from Oryza sativa subsp. japonica (Rice) (see 4 papers)
Q10CE4 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Oryza sativa Japonica Group (see paper)
    43% identity, 91% coverage of query (250 bits)

HAOX2_MOUSE / Q9NYQ2 2-Hydroxyacid oxidase 2; HAOX2; (S)-2-hydroxy-acid oxidase, peroxisomal; Medium chain alpha-hydroxy acid oxidase; Medium-chain L-2-hydroxy acid oxidase; EC 1.1.3.15 from Mus musculus (Mouse) (see paper)
Q9NYQ2 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Mus musculus (see paper)
    41% identity, 96% coverage of query (249 bits)

Q8H3I4 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Oryza sativa Japonica Group (see paper)
    43% identity, 91% coverage of query (248 bits)

GLO1_ARATH / Q9LRR9 Glycolate oxidase 1; AtGLO1; GOX1; (S)-2-hydroxy-acid oxidase GLO1; Short chain alpha-hydroxy acid oxidase GLO1; EC 1.1.3.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9LRR9 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Arabidopsis thaliana (see paper)
    42% identity, 92% coverage of query (247 bits)

HAOX2_RAT / Q07523 2-Hydroxyacid oxidase 2; HAOX2; (S)-2-hydroxy-acid oxidase, peroxisomal; Long chain alpha-hydroxy acid oxidase; Long-chain L-2-hydroxy acid oxidase; LCHAO; EC 1.1.3.15 from Rattus norvegicus (Rat) (see 5 papers)
    39% identity, 96% coverage of query (245 bits)

GOX1_MAIZE / A0A3L6E0R4 Glycolate oxidase 1; GOX; EC 1.1.3.15 from Zea mays (Maize) (see 2 papers)
    44% identity, 91% coverage of query (245 bits)

E1AXT8 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Nicotiana benthamiana (see 2 papers)
    40% identity, 98% coverage of query (244 bits)

LOX_ROSS0 / B7RR92 L-lactate oxidase; LOX; (S)-2-hydroxy-acid oxidase; EC 1.1.3.-; EC 1.1.3.15 from Roseobacter sp. (strain GAI101) (see paper)
    46% identity, 95% coverage of query (244 bits)

B9S0Y9 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Ricinus communis (see paper)
    40% identity, 98% coverage of query (244 bits)

B9ST74 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Ricinus communis (see paper)
    42% identity, 90% coverage of query (243 bits)

5zbmB / E1AXT8 Structure of glycolate oxidase containing fmn from nicotiana benthamiana (see paper)
    41% identity, 97% coverage of query (242 bits)

HAOX2_ARATH / Q24JJ8 Peroxisomal (S)-2-hydroxyacid oxidase GLO3; Glycolate oxidase 3; AtGLO3; GOX 3; Short chain alpha-hydroxy acid oxidase GLO3; lHAOX2; EC 1.1.3.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q24JJ8 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Arabidopsis thaliana (see paper)
    43% identity, 90% coverage of query (241 bits)

HAOX1_ARATH / Q9LJH5 Peroxisomal (S)-2-hydroxyacid oxidase GLO4; Glycolate oxidase 4; AtGLO4; GOX 4; lHAOX1; EC 1.1.3.15 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
Q9LJH5 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Arabidopsis thaliana (see paper)
    42% identity, 90% coverage of query (240 bits)

GOX_SPIOL / P05414 Glycolate oxidase; GAO; GOX; Short chain alpha-hydroxy acid oxidase; EC 1.1.3.15 from Spinacia oleracea (Spinach) (see 5 papers)
P05414 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Spinacia oleracea (see paper)
    40% identity, 97% coverage of query (240 bits)

5qieA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z2856434894
    39% identity, 96% coverage of query (239 bits)

7r4oA Structure of human hydroxyacid oxidase 1 bound with 2-((4h-1,2,4- triazol-3-yl)thio)-1-(4-(3-chlorophenyl)piperazin-1-yl)ethan-1-one
    39% identity, 96% coverage of query (239 bits)

7r4nA Structure of human hydroxyacid oxidase 1 bound with 5-bromo-n-methyl- 1h-indazole-3-carboxamide
    39% identity, 96% coverage of query (239 bits)

3sgzA / Q07523 High resolution crystal structure of rat long chain hydroxy acid oxidase in complex with the inhibitor 4-carboxy-5-[(4-chiorophenyl) sulfanyl]-1, 2, 3-thiadiazole. (see paper)
    39% identity, 96% coverage of query (238 bits)

1al7A Three-dimensional structures of glycolate oxidase with bound active- site inhibitors
    40% identity, 97% coverage of query (238 bits)

6gmcA 1.2 a resolution structure of human hydroxyacid oxidase 1 bound with fmn and 4-carboxy-5-[(4-chlorophenyl)sulfanyl]-1,2,3-thiadiazole
    38% identity, 96% coverage of query (238 bits)

HAOX1_MOUSE / Q9WU19 2-Hydroxyacid oxidase 1; HAOX1; Glycolate oxidase; GOX; Glyoxylate oxidase; EC 1.1.3.15; EC 1.2.3.5 from Mus musculus (Mouse) (see paper)
Q9WU19 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Mus musculus (see 3 papers)
    37% identity, 98% coverage of query (237 bits)

HAOX1_HUMAN / Q9UJM8 2-Hydroxyacid oxidase 1; HAOX1; Glycolate oxidase; GO; GOX; Glyoxylate oxidase; EC 1.1.3.15; EC 1.2.3.5 from Homo sapiens (Human) (see 4 papers)
Q9UJM8 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Homo sapiens (see 2 papers)
    38% identity, 98% coverage of query (236 bits)

LOX_LYSSC / B1HZY7 L-lactate oxidase; LOX; (S)-2-hydroxy-acid oxidase; EC 1.1.3.-; EC 1.1.3.15 from Lysinibacillus sphaericus (strain C3-41) (see paper)
    40% identity, 93% coverage of query (235 bits)

5qihA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z2697514548
    39% identity, 96% coverage of query (235 bits)

5qidA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z1787627869
    39% identity, 96% coverage of query (235 bits)

5qicA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z30620520
    39% identity, 96% coverage of query (235 bits)

5qibA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with fmopl000388a
    39% identity, 96% coverage of query (235 bits)

2rduA Crystal structure of human glycolate oxidase in complex with glyoxylate
    38% identity, 96% coverage of query (235 bits)

5qigA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z1407672867
    38% identity, 96% coverage of query (235 bits)

5qifA Pandda analysis group deposition of models with modelled events (e.G. Bound ligands) -- crystal structure of hao1 in complex with z31792168
    38% identity, 96% coverage of query (235 bits)

2rdwA Crystal structure of human glycolate oxidase in complex with sulfate
    38% identity, 96% coverage of query (235 bits)

6gmbA / Q9UJM8 Structure of human hydroxyacid oxidase 1 bound with fmn and glycolate
    38% identity, 96% coverage of query (234 bits)

1al8A Three-dimensional structure of glycolate oxidase with bound active- site inhibitors
    40% identity, 97% coverage of query (234 bits)

2w0uA Crystal structure of human glycolate oxidase in complex with the inhibitor 5-[(4-chlorophenyl)sulfanyl]- 1,2,3-thiadiazole-4- carboxylate.
    38% identity, 96% coverage of query (233 bits)

5zzqA / O52792 The crystal structure of mandelate oxidase with (s)-4-hydroxymandelic acid (see paper)
    43% identity, 93% coverage of query (230 bits)

HMO_AMYOR / O52792 4-hydroxymandelate oxidase; EC 1.1.3.46 from Amycolatopsis orientalis (Nocardia orientalis) (see 3 papers)
O52792 4-hydroxymandelate oxidase (EC 1.1.3.46) from Amycolatopsis orientalis (see 2 papers)
    43% identity, 93% coverage of query (230 bits)

6a08A / O52792 The crystal structure of mandelate oxidase with benzoyl-formic acid (see paper)
    43% identity, 93% coverage of query (229 bits)

7r4pA / Q9UJM8 Structure of human hydroxyacid oxidase 1 bound with 6-amino-1-benzyl- 5-(methylamino)pyrimidine-2,4(1h,3h)-dione
    38% identity, 96% coverage of query (229 bits)

6a24A The crystal structure of mandelate oxidase with 3-fluoropyruvate
    43% identity, 93% coverage of query (229 bits)

6a01A The crystal structure of mandelate oxidase y128f with 3,3-difluoro-2, 2-dihydroxy-3-phenylpropionic acid
    42% identity, 93% coverage of query (228 bits)

6a1aA Mandelate oxidase mutant-y128f with 4-hydroxymandelic acid
    42% identity, 93% coverage of query (228 bits)

6w4cA Crystal structure of hao1 in complex with indazole acid inhibitor - compound 5
    38% identity, 96% coverage of query (228 bits)

LOX_CHLRE / F8WQN2 L-lactate oxidase; LOX; Cr-LOX; EC 1.1.3.- from Chlamydomonas reinhardtii (Chlamydomonas smithii) (see paper)
F8WQN2 L-lactate oxidase (EC 1.1.3.2) from Chlamydomonas reinhardtii (see paper)
    41% identity, 88% coverage of query (226 bits)

7m2oA Crystal structure of human glycolate oxidase with inhibitor compound 15
    38% identity, 96% coverage of query (226 bits)

2rdtA Crystal structure of human glycolate oxidase (go) in complex with cdst
    38% identity, 96% coverage of query (226 bits)

6a1wA Mandelate oxidase with the enoyl fmn epoxide adduct
    42% identity, 93% coverage of query (226 bits)

6a00A The crystal structure of mandelate oxidase with (s)-2-phenylpropionate
    42% identity, 93% coverage of query (226 bits)

5zzrA The crystal structure of mandelate oxidase with (s)-mandelic acid
    42% identity, 93% coverage of query (226 bits)

5zztA The crystal structure of mandelate oxidase with 3,3-difluoro-2- hydroxy-3-phenylpropionic acid
    42% identity, 93% coverage of query (226 bits)

6w44A Crystal structure of hao1 in complex with indazole acid inhibitor - compound 4
    38% identity, 96% coverage of query (226 bits)

6a1bA Mandelate oxidase mutant-y128f with 3,3,3-trifluoro-2,2- dihydroxypropanoic acid
    42% identity, 93% coverage of query (225 bits)

6a11A Mandelate oxidase mutant-y128f with phenylpyruvic acid
    42% identity, 93% coverage of query (225 bits)

5zzxA The crystal structure of mandelate oxidase mutant y128f with (r)- mandelic acid
    42% identity, 93% coverage of query (225 bits)

6a36A Mandelate oxidase mutant-y128f with the 3-fluoropyruvic acid fmn adduct
    42% identity, 93% coverage of query (225 bits)

6a21A Mandelate oxidase mutant-y128f with the n5-malonyl-fmn adduct
    42% identity, 93% coverage of query (225 bits)

6a0bA The crystal structure of mandelate oxidase mutant y128f with (r)-3,3, 3-trifluoro-2-hydroxy-propionic acid
    42% identity, 93% coverage of query (225 bits)

6a1nA Mandelate oxidase mutant-y128f with (2r,3s)-3-fluoro-2-hydroxy-3- phenylpropanoic acid
    42% identity, 93% coverage of query (225 bits)

6a0gA The crystal structure of mandelate oxidase mutant y128f with b- phenyllactate
    42% identity, 93% coverage of query (225 bits)

6a23A Mandelate oxidase mutant-y128f with the n5-benzyl-fmn adduct
    42% identity, 93% coverage of query (225 bits)

6a1hA Mandelate oxidase mutant-y128f with 5-deazariboflavin mononucleotide
    42% identity, 93% coverage of query (225 bits)

6a0oA Mandelate oxidase mutant-y128f with benzaldehyde
    42% identity, 93% coverage of query (225 bits)

6a1rA Mandelate oxidase mutant-y128f with the n5-phenylacetyl-fmn adduct
    42% identity, 93% coverage of query (225 bits)

2j6xD The crystal structure of lactate oxidase
    36% identity, 98% coverage of query (224 bits)

7bsrA Mandelate oxidase with the 2-hydroxy-3-oxosuccinic acid
    42% identity, 93% coverage of query (224 bits)

6a39A The crystal structure of mandelate oxidase y128f with c4a-malic acid- monooxide-fmn adduct
    42% identity, 93% coverage of query (224 bits)

6a0mA Mandelate oxidase mutant-y128f with 2-phenylacetic acid
    42% identity, 93% coverage of query (224 bits)

FUB9_FUSO4 / A0A0D2YG00 Oxidase FUB9; Fusaric acid biosynthesis protein 9; EC 1.-.-.- from Fusarium oxysporum f. sp. lycopersici (strain 4287 / CBS 123668 / FGSC 9935 / NRRL 34936) (Fusarium vascular wilt of tomato) (see 8 papers)
    38% identity, 95% coverage of query (223 bits)

6a3tA The crystal structure of mandelate oxidase r163l with 2-hydroxy- phenylacetamide
    42% identity, 93% coverage of query (223 bits)

6w45A Crystal structure of hao1 in complex with biaryl acid inhibitor - compound 3
    37% identity, 96% coverage of query (223 bits)

6a4hA Mandelate oxidase mutant-y128f with the peroxide fmn adduct
    42% identity, 93% coverage of query (222 bits)

G4V4S8 4-hydroxymandelate oxidase (EC 1.1.3.46) from Amycolatopsis orientalis (see 2 papers)
    42% identity, 93% coverage of query (220 bits)

FUB9_GIBM7 / W7NCP1 Oxidase FUB9; Fusaric acid biosynthesis protein 9; EC 1.-.-.- from Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus) (Fusarium verticillioides) (see 9 papers)
    38% identity, 95% coverage of query (219 bits)

6a3dA The crystal structure of mandelate oxidase y128f with 4-br-2-hydroxy- methylphenylacetate
    43% identity, 88% coverage of query (218 bits)

2j6xH / Q44467 The crystal structure of lactate oxidase (see paper)
    35% identity, 98% coverage of query (217 bits)

lctO / D4YFM2 lactate oxidase monomer (EC 1.1.3.2) from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see 29 papers)
D4YFM2 L-lactate oxidase (EC 1.1.3.2) from Aerococcus viridans (see 2 papers)
    34% identity, 98% coverage of query (216 bits)

2e77A Crystal structure of l-lactate oxidase with pyruvate complex
    35% identity, 98% coverage of query (216 bits)

4rjeA Aerococcus viridans l-lactate oxidase mutant
    36% identity, 98% coverage of query (215 bits)

LOX_AERVM / Q44467 L-lactate oxidase; LOD; LOX; Lactate oxidase; EC 1.1.3.- from Aerococcus viridans (strain ATCC 11563 / DSM 20340 / CCUG 4311 / JCM 20461 / NBRC 12219 / NCTC 8251 / M1) (see 11 papers)
Q44467 L-lactate dehydrogenase (EC 1.1.1.27); L-lactate oxidase (EC 1.1.3.2) from Aerococcus viridans (see 18 papers)
2du2A / Q44467 Crystal structure analysis of the l-lactate oxidase (see paper)
    34% identity, 98% coverage of query (212 bits)

LOX_LACJE / A0A5N1I561 L-lactate oxidase; LOX; (S)-2-hydroxy-acid oxidase; EC 1.1.3.-; EC 1.1.3.15 from Lactobacillus jensenii (see paper)
    36% identity, 91% coverage of query (211 bits)

A0A0P0KG57 4-hydroxymandelate oxidase (EC 1.1.3.46) from Streptomyces sp. (see paper)
    44% identity, 93% coverage of query (211 bits)

6r9vA / E0NE46 Crystal structure of pediococcus acidilactici lactate oxidase a94g mutant (see paper)
    35% identity, 98% coverage of query (209 bits)

Q9CG58 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15) from Lactococcus lactis (see 2 papers)
    38% identity, 91% coverage of query (208 bits)

6m73A / I6SYK8 Crystal structure of enterococcus hirae l-lactate oxidase in complex with d-lactate form ligand
    34% identity, 96% coverage of query (206 bits)

6a4gA Mandelate oxidase mutant-y128f with the monooxide fmn adduct
    42% identity, 88% coverage of query (205 bits)

LOX_LENH9 / C0XIJ3 L-lactate oxidase; LOX; EC 1.1.3.- from Lentilactobacillus hilgardii (strain ATCC 8290 / DSM 20176 / CCUG 30140 / JCM 1155 / KCTC 3500 / NBRC 15886 / NCIMB 8040 / NRRL B-1843 / 9) (see paper)
    35% identity, 98% coverage of query (204 bits)

FUB9_GIBF5 / S0DRI9 Oxidase FUB9; Fusaric acid biosynthesis protein 9; EC 1.-.-.- from Gibberella fujikuroi (strain CBS 195.34 / IMI 58289 / NRRL A-6831) (Bakanae and foot rot disease fungus) (Fusarium fujikuroi) (see 8 papers)
    37% identity, 95% coverage of query (203 bits)

W1QKE8 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) from Ogataea angusta (see 2 papers)
    35% identity, 97% coverage of query (201 bits)

SM_b20850 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) from Sinorhizobium meliloti 1021
    35% identity, 88% coverage of query (199 bits)

QULF_PENCI / P0DUR7 FMN-dependent alpha-hydroxy acid dehydrogenase qulF; Quinolactacin A2 biosynthesis cluster protein F; EC 1.13.12.- from Penicillium citrinum (see paper)
    33% identity, 98% coverage of query (199 bits)

LOX_STRIN / O33655 L-lactate oxidase; LOX; EC 1.1.3.- from Streptococcus iniae (Streptococcus shiloi) (see paper)
O33655 L-lactate oxidase (EC 1.1.3.2) from Streptococcus iniae (see paper)
    33% identity, 98% coverage of query (197 bits)

A9QH69 (S)-2-hydroxy-acid oxidase (EC 1.1.3.15); L-lactate oxidase (EC 1.1.3.2) from Streptococcus iniae (see paper)
    34% identity, 96% coverage of query (196 bits)

Q9Z4X8 4-hydroxymandelate oxidase (EC 1.1.3.46) from Streptomyces coelicolor (see paper)
    47% identity, 94% coverage of query (196 bits)

2nliB / Q44467 Crystal structure of the complex between l-lactate oxidase and a substrate analogue at 1.59 angstrom resolution (see paper)
    34% identity, 98% coverage of query (195 bits)

A0A099P7X2 L-lactate dehydrogenase (cytochrome) (EC 1.1.2.3) from Pichia kudriavzevii (see paper)
    35% identity, 94% coverage of query (191 bits)

YKN3_SCHPO / Q9HDX2 FMN-dependent alpha-hydroxy acid dehydrogenase PB1A11.03; EC 1.13.12.- from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
    32% identity, 98% coverage of query (185 bits)

Build an alignment

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory