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Searching for up to 100 curated homologs for AZOBR_RS20225 FitnessBrowser__azobra:AZOBR_RS20225 (777 a.a.)

Found high-coverage hits (≥70%) to 5 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

FADN_BACSU / O32178 Probable 3-hydroxyacyl-CoA dehydrogenase; EC 1.1.1.35 from Bacillus subtilis (strain 168) (see paper)
    39% identity, 100% coverage of query (497 bits)

Q0KEG0 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); enoyl-CoA hydratase (EC 4.2.1.17) from Cupriavidus necator (see paper)
    34% identity, 100% coverage of query (402 bits)

corN / D7RK19 (3S,5E,8E)-3-hydroxy-5-methyldeca-5,8-dienoyl-[CorL PKS] dehydratase from Corallococcus coralloides (see 2 papers)
    32% identity, 100% coverage of query (316 bits)

Build an alignment

Build an alignment for AZOBR_RS20225 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

D3RXI4 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); 3-hydroxybutyryl-CoA dehydratase (EC 4.2.1.55) from Ferroglobus placidus (see paper)
    27% identity, 79% coverage of query (168 bits)

Msed_0399 / A4YDS4 crotonyl-CoA hydratase/(S)-3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.35; EC 4.2.1.150) from Metallosphaera sedula (strain ATCC 51363 / DSM 5348 / JCM 9185 / NBRC 15509 / TH2) (see 3 papers)
A4YDS4 3-hydroxybutyryl-CoA dehydrogenase (EC 1.1.1.157); 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35); short-chain-enoyl-CoA hydratase (EC 4.2.1.150) from Metallosphaera sedula (see 2 papers)
    24% identity, 78% coverage of query (122 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory