Searching for up to 100 curated homologs for AZOBR_RS21180 FitnessBrowser__azobra:AZOBR_RS21180 (760 a.a.)

Found high-coverage hits (≥70%) to 18 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

PFLB_STAAC / Q5HJF4 Formate acetyltransferase; Pyruvate formate-lyase; EC 2.3.1.54 from Staphylococcus aureus (strain COL) (see paper)
    66% identity, 97% coverage of query (1025 bits)

1h16A Pyruvate formate-lyase (e.Coli) in complex with pyruvate and coa
    65% identity, 97% coverage of query (1007 bits)

Pfl / b0903 pyruvate formate-lyase from Escherichia coli K-12 substr. MG1655 (see 3 papers)
pflB / P09373 pyruvate formate-lyase from Escherichia coli (strain K12) (see 28 papers)
PFLB_ECOLI / P09373 Formate acetyltransferase 1; Pyruvate formate-lyase 1; EC 2.3.1.54 from Escherichia coli (strain K12) (see 3 papers)
P09373 formate C-acetyltransferase (EC 2.3.1.54) from Escherichia coli (see 10 papers)
    65% identity, 97% coverage of query (1006 bits)

1cm5A / P09373 Crystal structure of c418a,c419a mutant of pfl from e.Coli (see paper)
    65% identity, 97% coverage of query (999 bits)

TDCE_ECOLI / P42632 PFL-like enzyme TdcE; Keto-acid formate acetyltransferase; Keto-acid formate-lyase; Ketobutyrate formate-lyase; KFL; Pyruvate formate-lyase; PFL; EC 2.3.1.-; EC 2.3.1.54 from Escherichia coli (strain K12) (see paper)
tdcE / EW|b3114 pyruvate formate-lyase 4/2-ketobutyrate formate-lyase from Escherichia coli K12 (see paper)
    64% identity, 98% coverage of query (978 bits)

pfl / Q46266 pyruvate formate-lyase subunit (EC 2.3.1.54) from Clostridium pasteurianum (see 6 papers)
Q46266 formate C-acetyltransferase (EC 2.3.1.54) from Clostridium pasteurianum (see paper)
    63% identity, 97% coverage of query (956 bits)

PFL1 / Q1RS83 pyruvate formate lyase (EC 2.3.1.54) from Chlamydomonas reinhardtii (see 6 papers)
Q1RS83 formate C-acetyltransferase (EC 2.3.1.54) from Chlamydomonas reinhardtii (see paper)
    60% identity, 95% coverage of query (920 bits)

pfl / Q59934 pyruvate formate-lyase subunit (EC 2.3.1.54) from Streptococcus mutans serotype c (strain ATCC 700610 / UA159) (see 2 papers)
    44% identity, 97% coverage of query (619 bits)

O66391 formate C-acetyltransferase (EC 2.3.1.54) from Streptococcus equinus (see paper)
    43% identity, 97% coverage of query (613 bits)

Q5M2Y4 formate C-acetyltransferase (EC 2.3.1.54) from Streptococcus thermophilus (see paper)
    43% identity, 97% coverage of query (608 bits)

A0A0H2ZQE4 formate C-acetyltransferase (EC 2.3.1.54) from Streptococcus pneumoniae (see paper)
    42% identity, 97% coverage of query (596 bits)

pfl / CAA03991.1 pyruvate formate-lyase from Lactococcus lactis (see paper)
    41% identity, 99% coverage of query (577 bits)

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Build an alignment for AZOBR_RS21180 and 12 homologs with ≥ 30% identity

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Additional hits (identity < 30%)

1r9dA / Q8GEZ8 Glycerol bound form of the b12-independent glycerol dehydratase from clostridium butyricum (see paper)
    27% identity, 86% coverage of query (189 bits)

Q8GEZ8 glycerol dehydratase (EC 4.2.1.30) from Clostridium butyricum (see 2 papers)
    27% identity, 86% coverage of query (189 bits)

YijL / b3951 putative formate acetyltransferase 2 from Escherichia coli K-12 substr. MG1655 (see 4 papers)
    25% identity, 88% coverage of query (146 bits)

t4LhypD / Q180C6 trans-4-hydroxy-L-proline dehydratase (EC 4.2.1.172) from Clostridioides difficile (strain 630) (see paper)
    25% identity, 71% coverage of query (137 bits)

HYPD_CLODI / A0A031WDE4 Trans-4-hydroxy-L-proline dehydratase; Glycyl radical enzyme; Hyp dehydratase; EC 4.2.1.172 from Clostridioides difficile (Peptoclostridium difficile) (see paper)
6vxeA / A0A031WDE4 Crystal structure of hydroxyproline dehydratase (hypd) from clostridioides difficile with substrate trans-4-hydroxy-l-proline bound (see paper)
    25% identity, 71% coverage of query (137 bits)

hpfG / A0A318FL05 (2S)-3-sulfopropanediol dehydratase (EC 4.2.1.177) from Klebsiella oxytoca (see paper)
HPFG_KLEOX / A0A318FL05 (2S)-3-sulfopropanediol dehydratase; (S)-DHPS dehydratase; EC 4.2.1.177 from Klebsiella oxytoca (see paper)
A0A318FL05 (2S)-3-sulfopropanediol dehydratase (EC 4.2.1.177) from Klebsiella oxytoca (see paper)
    24% identity, 76% coverage of query (111 bits)

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