Sites on a Tree

 

Searching for up to 100 curated homologs for AZOBR_RS25735 FitnessBrowser__azobra:AZOBR_RS25735 (537 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

AAS80455.1 α,α-trehalase / α-glucosidase (TTC0107) (EC 3.2.1.20|3.2.1.28) (see protein)
    55% identity, 98% coverage of query (559 bits)

Q5SL12 alpha-glucosidase (EC 3.2.1.20) from Thermus thermophilus HB8 (see paper)
BAD70304.1 α-glucosidase (TTHA0481) (EC 3.2.1.20) (see protein)
    55% identity, 98% coverage of query (557 bits)

BAB18518.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    55% identity, 98% coverage of query (555 bits)

AAD50603.1 α-glucosidase (EC 3.2.1.20) (see protein)
    54% identity, 98% coverage of query (553 bits)

AKA95141.1 α-glucosidase (TtAG) (EC 3.2.1.20) (see protein)
    54% identity, 98% coverage of query (549 bits)

BAL49684.1 α-glucosidase (AglA;HaG) (EC 3.2.1.20) (see protein)
    43% identity, 91% coverage of query (416 bits)

Shewana3_2311 Alpha-glucosidase (EC 3.2.1.20) from Shewanella sp. ANA-3
    40% identity, 96% coverage of query (415 bits)

3wy1A / H3K096 Crystal structure of alpha-glucosidase (see paper)
    43% identity, 90% coverage of query (412 bits)

3wy2A Crystal structure of alpha-glucosidase in complex with glucose
    43% identity, 90% coverage of query (412 bits)

3wy4A Crystal structure of alpha-glucosidase mutant e271q in complex with maltose
    43% identity, 90% coverage of query (411 bits)

PGA1_c07890 cytoplasmic trehalase (AlgA) from Phaeobacter inhibens BS107
    41% identity, 95% coverage of query (408 bits)

BAC87873.1 α-transglucosidase (XgtA) (EC 2.4.1.-) (see protein)
    43% identity, 93% coverage of query (405 bits)

Dshi_1649 alpha-glucosidase / maltase / trehalase / sucrase (EC 3.2.1.48; EC 3.2.1.20; EC 3.2.1.28) from Dinoroseobacter shibae DFL-12
    41% identity, 96% coverage of query (404 bits)

CAA60858.1 α-glucosidase (Agm2) (EC 3.2.1.20) (see protein)
    41% identity, 97% coverage of query (397 bits)

CAA54266.1 α-glucosidase (EC 3.2.1.20) (see protein)
CAA54266.1 alpha-glucosidase from Bacillus sp. (see paper)
    41% identity, 89% coverage of query (396 bits)

A0A223KY92 alpha-amylase (EC 3.2.1.1) from Sutcliffiella cohnii (see paper)
    40% identity, 93% coverage of query (396 bits)

Q9Z3R8 alpha-glucosidase (EC 3.2.1.20) from Sinorhizobium meliloti (see paper)
    43% identity, 89% coverage of query (396 bits)

Psest_0870 Alpha-glucosidase (EC 3.2.1.20) from Pseudomonas stutzeri RCH2
    44% identity, 91% coverage of query (391 bits)

bsPTRE / BAE45038.1 trehalose-6-phosphate hydrolase from Geobacillus stearothermophilus (see paper)
    37% identity, 97% coverage of query (389 bits)

BAE86927.1 α-glucosidase II (Hbg2;HBG-II;Loc411257) (EC 3.2.1.20) (see protein)
    41% identity, 91% coverage of query (387 bits)

ADD81256.1 α-amylase (Aamy1) (EC 3.2.1.20) (see protein)
    44% identity, 87% coverage of query (384 bits)

AAF71997.1 α-glucosidase (EC 3.2.1.20) (see protein)
    37% identity, 97% coverage of query (383 bits)

2ze0A / Q33E90 Alpha-glucosidase gsj (see paper)
    42% identity, 89% coverage of query (380 bits)

M1E1F6 isomaltulose synthase (EC 5.4.99.11) from Rhizobium sp. MX-45 (see paper)
    39% identity, 93% coverage of query (379 bits)

Q2PS28 isomaltulose synthase (EC 5.4.99.11) from Paraburkholderia acidicola (see 3 papers)
    39% identity, 93% coverage of query (379 bits)

MAL1_DROME / P07190 Maltase A1; Larval visceral protein H; EC 3.2.1.20 from Drosophila melanogaster (Fruit fly) (see paper)
AAF59089.3 α-glucosidase H (LvpH; RE72980p) (EC 3.2.1.20) (see protein)
    40% identity, 91% coverage of query (379 bits)

M1E1F7 isomaltulose synthase (EC 5.4.99.11) from Rhizobium sp. (see paper)
    39% identity, 93% coverage of query (378 bits)

Q33E90 alpha-glucosidase (EC 3.2.1.20) from Geobacillus sp. HTA-462 (see paper)
BAE48285.1 α-glucosidase (Gsj) (EC 3.2.1.20) (see protein)
    41% identity, 89% coverage of query (378 bits)

4h8vA / M1E1F6 Crystal structure of the trehalulose synthase mutb in complex with trehalulose
    39% identity, 93% coverage of query (378 bits)

BAA12704.1 α-glucosidase / exo-α-1,4-glucosidase (EC 3.2.1.20) (see protein)
    41% identity, 89% coverage of query (378 bits)

2pwdA Crystal structure of the trehalulose synthase mutb from pseudomonas mesoacidophila mx-45 complexed to the inhibitor deoxynojirmycin
    39% identity, 93% coverage of query (378 bits)

2pwgA Crystal structure of the trehalulose synthase mutb from pseudomonas mesoacidophila mx-45 complexed to the inhibitor castanospermine
    39% identity, 93% coverage of query (378 bits)

6k5pA / B0X223 Structure of mosquito-larvicidal binary toxin receptor, cqm1 (see paper)
    40% identity, 97% coverage of query (377 bits)

BAA11354.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    37% identity, 97% coverage of query (377 bits)

J9SJ08 alpha-glucosidase (EC 3.2.1.20); mannosyl-oligosaccharide alpha-1,3-glucosidase (EC 3.2.1.207) from Apis cerana indica (see paper)
    41% identity, 91% coverage of query (377 bits)

A0A222C758 4-alpha-glucanotransferase (EC 2.4.1.25) from Culex quinquefasciatus (see paper)
    40% identity, 98% coverage of query (377 bits)

CAA55409.1 α-1,4-glucosidase (MalA) (EC 3.2.1.20) (see protein)
    38% identity, 90% coverage of query (377 bits)

ABW98683.1 α-glucosidase / binding-toxin receptor (Agm3;AgAgm3) (EC 3.2.1.20) (see protein)
    43% identity, 91% coverage of query (377 bits)

ACN63343.1 sucrase / α-glucosidase II (JBgII;HBGaseII) (EC 3.2.1.20|3.2.1.-) (see protein)
    41% identity, 91% coverage of query (377 bits)

6k5pC Structure of mosquito-larvicidal binary toxin receptor, cqm1
    40% identity, 97% coverage of query (377 bits)

6k5pB Structure of mosquito-larvicidal binary toxin receptor, cqm1
    40% identity, 97% coverage of query (377 bits)

2pweA Crystal structure of the mutb e254q mutant in complex with the substrate sucrose
    39% identity, 93% coverage of query (377 bits)

O16G_PARTM / P29094 Oligo-1,6-glucosidase; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase; Sucrase-isomaltase; Isomaltase; EC 3.2.1.10 from Parageobacillus thermoglucosidasius (Geobacillus thermoglucosidasius) (see paper)
BAA01368.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    38% identity, 97% coverage of query (376 bits)

M1E1F3 isomaltulose synthase (EC 5.4.99.11) from Rhizobium sp. (see paper)
    39% identity, 93% coverage of query (376 bits)

2pwfA Crystal structure of the mutb d200a mutant in complex with glucose
    39% identity, 93% coverage of query (375 bits)

4ha1A Mutb inactive double mutant d200a-d415n in complex with isomaltulose
    39% identity, 93% coverage of query (374 bits)

MALT_CULPI / Q95WY5 Alpha-glucosidase; Binary toxin-binding alpha-glucosidase; Culex pipiens maltase 1; Cpm1; EC 3.2.1.20 from Culex pipiens (House mosquito) (see 2 papers)
AAL05443.1 α-glucosidase / maltase 1 (Cpm1) (binary toxin-binding) (EC 3.2.1.20) (see protein)
    39% identity, 98% coverage of query (373 bits)

4mazA The structure of mall mutant enzyme v200s from bacillus subtilus
    36% identity, 97% coverage of query (373 bits)

O16G1_BACSU / O06994 Oligo-1,6-glucosidase 1; Dextrin 6-alpha-D-glucanohydrolase; Oligosaccharide alpha-1,6-glucosidase 1; Sucrase-isomaltase 1; Isomaltase 1; EC 3.2.1.10 from Bacillus subtilis (strain 168) (see 3 papers)
CAB15461.1 α-1,6-glucosidase (MalL;YvdL;BSU34560) (EC 3.2.1.10) (see protein)
    36% identity, 97% coverage of query (372 bits)

7lv6B / O06994 The structure of mall mutant enzyme s536r from bacillus subtilis
    36% identity, 97% coverage of query (372 bits)

MAL3_DROME / P07192 Maltase A3; Larval visceral protein L; EC 3.2.1.20 from Drosophila melanogaster (Fruit fly) (see paper)
AAM50308.1 α-glucosidase L (LvpL) (EC 3.2.1.20) (see protein)
    39% identity, 97% coverage of query (370 bits)

CAA37583.1 oligo-α-1,6-glucosidase (MalL) (EC 3.2.1.10) (see protein)
    36% identity, 97% coverage of query (370 bits)

5wczA Crystal structure of wild-type mall from bacillus subtilis with ts analogue 1-deoxynojirimycin
    36% identity, 97% coverage of query (370 bits)

4m56A The structure of wild-type mall from bacillus subtilis
    36% identity, 97% coverage of query (370 bits)

AAB82328.1 α-glucosidase 2 (Mav2) (EC 3.2.1.20) (see protein)
    41% identity, 87% coverage of query (369 bits)

BAA11466.1 α-glucosidase III (Hbg3;HBG-III;Loc406131) (EC 3.2.1.20) (see protein)
    39% identity, 90% coverage of query (369 bits)

ADB11049.1 α-glucosidase III (EC 3.2.1.20) (see protein)
    39% identity, 90% coverage of query (369 bits)

ACE77085.1 oligosaccharide-producing multifunctional amylase (OPMA) (EC 2.4.1.-) (see protein)
    36% identity, 97% coverage of query (369 bits)

SLC31_HUMAN / Q07837 Amino acid transporter heavy chain SLC3A1; D2h; Neutral and basic amino acid transport protein; NBAT; Solute carrier family 3 member 1; b(0,+)-type amino acid transporter-related heavy chain; rBAT from Homo sapiens (Human) (see 24 papers)
    37% identity, 98% coverage of query (367 bits)

6li9A / Q07837 Heteromeric amino acid transporter b0,+at-rbat complex bound with arginine (see paper)
    37% identity, 98% coverage of query (367 bits)

AAB82327.1 α-glucosidase 1 (Mav1) (EC 3.2.1.20) (see protein)
    38% identity, 98% coverage of query (365 bits)

C1DMP8 isomaltulose synthase (EC 5.4.99.11) from Azotobacter vinelandii (see paper)
    40% identity, 97% coverage of query (365 bits)

ABB55878.1 sucrase / α-glucosidase (S1;APS1) (EC 3.2.1.20) (see protein)
    41% identity, 82% coverage of query (363 bits)

SLC31_RAT / Q64319 Amino acid transporter heavy chain SLC3A1; D2; Neutral and basic amino acid transport protein; NBAT; Solute carrier family 3 member 1; b(0,+)-type amino acid transporter-related heavy chain; NAA-TR; rBAT from Rattus norvegicus (Rat) (see 3 papers)
    37% identity, 97% coverage of query (362 bits)

ABO27432.1 α-glucosidase (EC 3.2.1.20) (see protein)
    39% identity, 90% coverage of query (362 bits)

AAP10934.1 oligo-α-1,6-glucosidase (BC4015) (EC 3.2.1.10) (see protein)
    35% identity, 97% coverage of query (362 bits)

Q9F4G4 oligo-1,6-glucosidase (EC 3.2.1.10) from Bacillus subtilis (see paper)
AAG23399.1 oligo-α-1,6-glucosidase (EC 3.2.1.10) (see protein)
    36% identity, 97% coverage of query (362 bits)

CAA02858.1 palatinase / trehalulose hydrolase (MutA) (EC 3.2.1.10|3.2.1.-) (see protein)
    41% identity, 89% coverage of query (361 bits)

8ibkA / A0A2Z5WH92 Crystal structure of bacillus sp. Ahu2216 gh13_31 alpha-glucosidase e256q/n258g in complex with maltotriose (see paper)
    37% identity, 93% coverage of query (360 bits)

Q6XNK5 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see paper)
    36% identity, 89% coverage of query (359 bits)

palI / Q9AI64 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see 2 papers)
Q9AI64 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see paper)
    36% identity, 89% coverage of query (357 bits)

MAL2_DROME / P07191 Maltase A2; Larval visceral protein D; EC 3.2.1.20 from Drosophila melanogaster (Fruit fly) (see paper)
AAF59088.1 α-glucosidase D (LvpD) (EC 3.2.1.20) (see protein)
    37% identity, 97% coverage of query (357 bits)

D9MPF2 isomaltulose synthase (EC 5.4.99.11) from Erwinia rhapontici (see 3 papers)
    36% identity, 89% coverage of query (357 bits)

BAG86620.1 trehalose-6-phosphate hydrolase (TreC;KP1_0530) (EC 3.2.1.93) (see protein)
    39% identity, 97% coverage of query (357 bits)

4howA / D9MPF2 The crystal structure of isomaltulose synthase from erwinia rhapontici nx5 (see paper)
    36% identity, 89% coverage of query (357 bits)

AAK27723.1 oligo α-glucosidase (AglA) (EC 3.2.1.10) (see protein)
    37% identity, 93% coverage of query (355 bits)

S5YEW8 isomaltulose synthase (EC 5.4.99.11) from Pectobacterium carotovorum (see paper)
    37% identity, 96% coverage of query (355 bits)

4hphA The crystal structure of isomaltulose synthase mutant e295q from erwinia rhapontici nx5 in complex with its natural substrate sucrose
    36% identity, 89% coverage of query (355 bits)

AAK28739.1 α-glucosidase (PalZ) (EC 3.2.1.20) (see protein)
    40% identity, 91% coverage of query (354 bits)

4hozA The crystal structure of isomaltulose synthase mutant d241a from erwinia rhapontici nx5 in complex with d-glucose
    36% identity, 89% coverage of query (354 bits)

treA / P39795 trehalose-6-phosphate hydrolase (EC 3.2.1.93) from Bacillus subtilis (strain 168) (see paper)
TREC_BACSU / P39795 Trehalose-6-phosphate hydrolase; Alpha,alpha-phosphotrehalase; Phospho-alpha-(1-1)-glucosidase; EC 3.2.1.93 from Bacillus subtilis (strain 168) (see 2 papers)
CAB12610.1 trehalose-6-phosphate hydrolase (TreA;BSU07810) (EC 3.2.1.93) (see protein)
    35% identity, 97% coverage of query (353 bits)

7nf6A / W5P8K2 Ovine b0,+at-rbat heterodimer (see paper)
    36% identity, 98% coverage of query (352 bits)

6lgbA Bombyx mori gh13 sucrose hydrolase complexed with glucose
    37% identity, 97% coverage of query (352 bits)

6lgaA / A0A077JI83 Bombyx mori gh13 sucrose hydrolase (see paper)
    37% identity, 97% coverage of query (351 bits)

SLC31_MOUSE / Q91WV7 Amino acid transporter heavy chain SLC3A1; D2; Neutral and basic amino acid transport protein; NBAT; Solute carrier family 3 member 1; b(0,+)-type amino acid transporter-related heavy chain; rBAT from Mus musculus (Mouse) (see 2 papers)
    36% identity, 98% coverage of query (351 bits)

6lgeA Bombyx mori gh13 sucrose hydrolase complexed with acarbose
    37% identity, 97% coverage of query (351 bits)

6lgdA Bombyx mori gh13 sucrose hydrolase complexed with 1,4-dideoxy-1,4- imino-d-arabinitol
    37% identity, 97% coverage of query (351 bits)

6lgcA Bombyx mori gh13 sucrose hydrolase complexed with 1-deoxynojirimycin
    37% identity, 97% coverage of query (351 bits)

Q65MI2 alpha,alpha-phosphotrehalase (EC 3.2.1.93) from Bacillus licheniformis (see 2 papers)
AAU39732.1 trehalose-6-P hydrolase (TreA;BlTreA;BLi00797;BL03069) (EC 3.2.1.93) (see protein)
    35% identity, 92% coverage of query (350 bits)

6lgiA Bombyx mori gh13 sucrose hydrolase mutant e322q covalent intermediate complexed with fructose
    36% identity, 97% coverage of query (350 bits)

6lgfA Bombyx mori gh13 sucrose hydrolase mutant d247n complexed with sucrose
    36% identity, 97% coverage of query (350 bits)

TreE / b4239 trehalose-6-phosphate hydrolase (EC 3.2.1.93) from Escherichia coli K-12 substr. MG1655 (see 7 papers)
treC / P28904 trehalose-6-phosphate hydrolase (EC 3.2.1.93) from Escherichia coli (strain K12) (see 4 papers)
TREC_ECOLI / P28904 Trehalose-6-phosphate hydrolase; Alpha,alpha-phosphotrehalase; EC 3.2.1.93 from Escherichia coli (strain K12) (see paper)
AAC77196.1 trehalose-6-phosphate hydrolase (TreC) (EC 3.2.1.93) (see protein)
    36% identity, 97% coverage of query (348 bits)

5brpA / Q65MI2 Crystal structure of bacillus licheniformis trehalose-6-phosphate hydrolase (trea), mutant r201q, in complex with png (see paper)
    35% identity, 92% coverage of query (348 bits)

B5ABD8 isomaltulose synthase (EC 5.4.99.11) from Enterobacter sp. FMB-1 (see 3 papers)
    35% identity, 96% coverage of query (348 bits)

agdF maltase MalT (AFU_orthologue; AFUA_8G07070) from Emericella nidulans (see paper)
    38% identity, 97% coverage of query (348 bits)

5do8B / Q8YAE6 1.8 angstrom crystal structure of listeria monocytogenes lmo0184 alpha-1,6-glucosidase (see paper)
    35% identity, 97% coverage of query (348 bits)

MALT_SCHPO / Q9P6J3 Alpha-glucosidase; Maltase; EC 3.2.1.20 from Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast) (see paper)
mal1 / RF|NP_595063.1 maltase alpha-glucosidase Mal1; EC 3.2.1.20 from Schizosaccharomyces pombe (see 2 papers)
    34% identity, 97% coverage of query (347 bits)

7p01A Structure of the maltase baag2 from blastobotrys adeninivorans in complex with acarbose (see paper)
    36% identity, 97% coverage of query (347 bits)

BAB59003.1 α-glucosidase / maltase (MalT;AO090038000234) (EC 3.2.1.20) (see protein)
    37% identity, 90% coverage of query (346 bits)

C0JP82 oligo-1,6-glucosidase (EC 3.2.1.10) from Bifidobacterium breve (see paper)
ACM89182.1 α-1,6-glucosidase 1 (Agl1; Bbr_1855) (EC 3.2.1.10|3.2.1.20) (see protein)
    38% identity, 94% coverage of query (345 bits)

Build an alignment

Build an alignment for AZOBR_RS25735 and 100 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory