Searching for up to 100 curated homologs for AZOBR_RS26375 AZOBR_RS26375 hypothetical protein (293 a.a.)
Found high-coverage hits (≥70%) to 45 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
YISK_BACSU / O06724 Uncharacterized protein YisK from Bacillus subtilis (strain 168) (see paper)
54% identity, 83% coverage of query (259 bits)
6iymA / K0A9N9 Fumarylacetoacetate hydrolase (eafah) from psychrophilic exiguobacterium antarcticum (see paper)
42% identity, 99% coverage of query (204 bits)
dntG / Q8VUC7 2,4-dihydroxy-5-methyl-6-oxohexa-2,4-dienoate isomerase from Burkholderia cepacia (see 2 papers)
37% identity, 100% coverage of query (186 bits)
SM_b21112 L-2,4-diketo-3-deoxyrhamnonate hydrolase; 2,4-dioxopentanoate hydrolase from Sinorhizobium meliloti 1021
42% identity, 72% coverage of query (171 bits)
Y2993_MYCTU / I6Y276 Protein Rv2993c from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
39% identity, 94% coverage of query (167 bits)
6jvwB / G2IPX5 Crystal structure of maleylpyruvate hydrolase from sphingobium sp. Syk-6 in complex with manganese (ii) ion and pyruvate (see paper)
38% identity, 87% coverage of query (163 bits)
BPHYT_RS34210 2,4-diketo-3-deoxy-L-rhamnonate hydrolase (EC 3.7.1.-) from Burkholderia phytofirmans PsJN
40% identity, 73% coverage of query (162 bits)
3qdfA / B2HIH3 Crystal structure of 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase from mycobacterium marinum (see paper)
40% identity, 79% coverage of query (159 bits)
UGL_BURL3 / Q39BA7 Ureidoglycolate lyase; UGL; Ureidoglycolase; Ureidoglycolatase; Ureidoglycolate hydrolase; EC 4.3.2.3 from Burkholderia lata (strain ATCC 17760 / DSM 23089 / LMG 22485 / NCIMB 9086 / R18194 / 383) (see paper)
43% identity, 71% coverage of query (158 bits)
HSERO_RS06355 2,4-diketo-3-deoxy-L-fuconate hydrolase (EC 3.7.1.26) from Herbaspirillum seropedicae SmR1
41% identity, 72% coverage of query (156 bits)
lra6 / Q1NEI7 L-2,4-diketo-3-deoxyrhamnonate hydrolase (EC 3.7.1.26) from Sphingomonas sp. (strain SKA58) (see paper)
36% identity, 98% coverage of query (155 bits)
8gsrA / Q1NEI7 Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Apo-form) (see paper)
36% identity, 97% coverage of query (153 bits)
8gstC Crystal structure of l-2,4-diketo-3-deoxyrhamnonate hydrolase from sphingomonas sp. (Pyruvate bound-form)
36% identity, 97% coverage of query (153 bits)
6v77B / A0QTY3 Crystal structure of a putative hpce protein from mycobacterium smegmatis
37% identity, 99% coverage of query (152 bits)
3r6oA / B1MJ53 Crystal structure of a probable 2-hydroxyhepta-2,4-diene-1, 7- dioateisomerase from mycobacterium abscessus (see paper)
37% identity, 78% coverage of query (145 bits)
6j5xA / Q8NLC0 Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate (see paper)
34% identity, 80% coverage of query (144 bits)
6j5xB Crystal structure of fumarylpyruvate hydrolase from corynebacterium glutamicum in complex with mn2+ and pyruvate
34% identity, 80% coverage of query (144 bits)
4dbhA / Q8NQY2 Crystal structure of cg1458 with inhibitor (see paper)
36% identity, 79% coverage of query (142 bits)
FAHD1_ARATH / Q93ZE5 Probable acylpyruvase FAHD1, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 1; FAH domain-containing protein 1; EC 3.7.1.5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
38% identity, 73% coverage of query (140 bits)
FAHD1_MOUSE / Q8R0F8 Acylpyruvase FAHD1, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 1; Oxaloacetate decarboxylase; OAA decarboxylase; EC 3.7.1.5; EC 4.1.1.112 from Mus musculus (Mouse) (see 2 papers)
38% identity, 72% coverage of query (134 bits)
6sbiA / Q8R0F8 X-ray structure of murine fumarylacetoacetate hydrolase domain containing protein 1 (fahd1) in complex with inhibitor oxalate (see paper)
38% identity, 72% coverage of query (134 bits)
FAHD2_ARATH / Q9LUR3 Probable acylpyruvase FAHD2, mitochondrial; Fumarylacetoacetate hydrolase domain-containing protein 2; FAH domain-containing protein 2; EC 3.7.1.5 from Arabidopsis thaliana (Mouse-ear cress) (see paper)
37% identity, 73% coverage of query (127 bits)
HBZF_PSEAC / Q0QFQ3 Maleylpyruvate hydrolase; MPH11; EC 3.7.1.23 from Pseudomonas alcaligenes (see 3 papers)
Q0QFQ3 maleylpyruvate hydrolase (EC 3.7.1.23) from Pseudomonas alcaligenes (see paper)
hbzF / Q0QFQ3 maleylpyruvate hydrolase monomer (EC 3.7.1.23) from Pseudomonas alcaligenes (see 2 papers)
35% identity, 79% coverage of query (126 bits)
6j5yA / Q9I111 Crystal structure of fumarylpyruvate hydrolase from pseudomonas aeruginosa in complex with mn2+ and pyruvate (see paper)
37% identity, 74% coverage of query (123 bits)
naaD / F8QQ75 3-fumarylpyruvate hydrolase (EC 3.7.1.20) from Bradyrhizobium sp. JS329 (see paper)
36% identity, 74% coverage of query (123 bits)
CPH_NEONM / A0A3G9JYJ6 Caffeoylpyruvate hydrolase; CPH; Fungal bioluminescence cycle protein cph; EC 3.7.-.- from Neonothopanus nambi (Agaricus nambi) (see 2 papers)
35% identity, 80% coverage of query (117 bits)
FMP41_YEAST / P53889 Uncharacterized mitochondrial hydrolase FMP41; EC 3.-.-.- from Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) (see 4 papers)
31% identity, 75% coverage of query (110 bits)
YcgM / b1180 putative isomerase/hydrolase from Escherichia coli K-12 substr. MG1655 (see 2 papers)
33% identity, 75% coverage of query (110 bits)
1nkqA / P53889 Crystal structure of yeast ynq8, a fumarylacetoacetate hydrolase family protein
31% identity, 75% coverage of query (106 bits)
3v77A / D2YW46 Crystal structure of a putative fumarylacetoacetate isomerase/hydrolase from oleispira antarctica (see paper)
32% identity, 74% coverage of query (105 bits)
1nr9D / P76004 Crystal structure of escherichia coli 1262 (apc5008), putative isomerase
32% identity, 75% coverage of query (103 bits)
1nr9B / P76004 Crystal structure of escherichia coli 1262 (apc5008), putative isomerase
32% identity, 75% coverage of query (103 bits)
1nr9C / P76004 Crystal structure of escherichia coli 1262 (apc5008), putative isomerase
31% identity, 75% coverage of query (99.8 bits)
1nr9A / P76004 Crystal structure of escherichia coli 1262 (apc5008), putative isomerase
31% identity, 75% coverage of query (99.8 bits)
HPCE_ECOLX / P37352 Homoprotocatechuate catabolism bifunctional isomerase/decarboxylase; EC 5.3.3.10; EC 4.1.1.68 from Escherichia coli (see 2 papers)
31% identity, 73% coverage of query (87.8 bits)
hpaG / Q46978 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioate decarboxylase (EC 4.1.1.68) from Escherichia coli (see 2 papers)
30% identity, 73% coverage of query (85.5 bits)
1gttA / P37352 Crystal structure of hpce (see paper)
30% identity, 73% coverage of query (85.5 bits)
Build an alignment for AZOBR_RS26375 and 37 homologs with ≥ 30% identity
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FAHA_ASPFU / Q4WHT8 Fumarylacetoacetase fahA; Fumarylacetoacetate hydrolase fahA; L-tyrosine degradation gene cluster protein fahA; Pyomelanin biosynthesis cluster protein fahA; EC 3.7.1.2 from Aspergillus fumigatus (strain ATCC MYA-4609 / CBS 101355 / FGSC A1100 / Af293) (Neosartorya fumigata) (see 3 papers)
24% identity, 86% coverage of query (56.6 bits)
KDXD_HALVD / D4GP28 Probable 2-keto-3-deoxyxylonate dehydratase; KDXD; EC 4.2.1.141 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see 2 papers)
xacE / D4GP28 2-dehydro-3-deoxy-L-arabinonate dehydratase (EC 4.2.1.43; EC 4.2.1.141) from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (see 3 papers)
25% identity, 76% coverage of query (53.5 bits)
3bqbX / Q97UA0 Hexagonal kristal form of 2-keto-3-deoxyarabinonate dehydratase (see paper)
26% identity, 78% coverage of query (50.8 bits)
2q1cX 2-keto-3-deoxy-d-arabinonate dehydratase complexed with calcium and 2- oxobutyrate
26% identity, 78% coverage of query (50.8 bits)
2q1aX 2-keto-3-deoxy-d-arabinonate dehydratase complexed with magnesium and 2-oxobutyrate
26% identity, 78% coverage of query (50.8 bits)
KDAD_SACS2 / Q97UA0 2-dehydro-3-deoxy-D-arabinonate dehydratase; 2-keto-3-deoxy-D-arabinonate dehydratase; KdaD; EC 4.2.1.141 from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (Sulfolobus solfataricus) (see 2 papers)
Q97UA0 2-dehydro-3-deoxy-D-arabinonate dehydratase (EC 4.2.1.141) from Saccharolobus solfataricus (see 2 papers)
kdaD / Q97UA0 2-keto-3-deoxy-D-arabinonate dehydratase subunit (EC 4.2.1.141) from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see 2 papers)
26% identity, 78% coverage of query (50.4 bits)
2q1dX 2-keto-3-deoxy-d-arabinonate dehydratase complexed with magnesium and 2,5-dioxopentanoate
27% identity, 78% coverage of query (49.3 bits)
FAAA_EMENI / Q00770 Fumarylacetoacetase; FAA; Beta-diketonase; Fumarylacetoacetate hydrolase; EC 3.7.1.2 from Emericella nidulans (strain FGSC A4 / ATCC 38163 / CBS 112.46 / NRRL 194 / M139) (Aspergillus nidulans) (see paper)
22% identity, 82% coverage of query (45.4 bits)
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Lawrence Berkeley National Laboratory