Searching for up to 100 curated homologs for AZOBR_RS27990 FitnessBrowser__azobra:AZOBR_RS27990 (310 a.a.)
Found high-coverage hits (≥70%) to 41 curated proteins.
You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.
TC 3.A.1.1.37 / Q9WYB4 Predicted arabinoside porter. Regulated by arabinose-responsive regulator AraR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
35% identity, 84% coverage of query (149 bits)
HSERO_RS17005 ABC transporter for D-sorbitol/xylitol, permease component 1 from Herbaspirillum seropedicae SmR1
36% identity, 71% coverage of query (140 bits)
TC 3.A.1.1.41 / G4FGN7 ABC-type transporter, integral membrane subunit, component of Trehalose porter. Also binds sucrose (Boucher and Noll, 2011). Induced by glucose and trehalose. Directly regulated by trehalose-responsive regulator TreR from Thermotoga maritima (strain ATCC 43589 / MSB8 / DSM 3109 / JCM 10099)
33% identity, 86% coverage of query (131 bits)
SM_b21104 ABC transporter for L-Fucose, permease component 1 from Sinorhizobium meliloti 1021
31% identity, 75% coverage of query (120 bits)
TC 3.A.1.1.25 / Q72H67 Maltose transport system permease protein malF aka TT_C1628, component of The trehalose/maltose/sucrose/palatinose porter (TTC1627-9) plus MalK1 (ABC protein, shared with 3.A.1.1.24) (Silva et al. 2005; Chevance et al., 2006). The receptor (TTC1627) binds disaccharide alpha-glycosides, namely trehalose (alpha-1,1), sucrose (alpha-1,2), maltose (alpha-1,4), palatinose (alpha-1,6) and glucose from Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM 7039) (see paper)
35% identity, 72% coverage of query (117 bits)
TC 3.A.1.1.19 / Q8L125 PalF, component of Platinose (isomaltulose) (6-O-α-D-glucopyranosyl-D-fructofuranose) porter from Agrobacterium tumefaciens (see 3 papers)
30% identity, 95% coverage of query (116 bits)
SM_b20326 ABC transporter for D-trehalose/D-maltose/sucrose, permease component 1 (ThuF) from Sinorhizobium meliloti 1021
TC 3.A.1.1.17 / Q9R9Q6 ThuF aka RB0312 aka SMB20326, component of Trehalose/maltose/sucrose porter (trehalose inducible) from Rhizobium meliloti (Sinorhizobium meliloti) (see 3 papers)
35% identity, 74% coverage of query (116 bits)
MALF_THELN / O51924 Trehalose/maltose transport system permease protein MalF from Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) (see 3 papers)
37% identity, 70% coverage of query (112 bits)
Build an alignment for AZOBR_RS27990 and 8 homologs with ≥ 30% identity
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Q6MNM0 ABC-type maltose transporter (EC 7.5.2.1) from Bdellovibrio bacteriovorus (see paper)
TC 3.A.1.1.51 / Q6MNM0 Maltose - maltoheptose transporter, MalEFGK from Bdellovibrio bacteriovorus (strain ATCC 15356 / DSM 50701 / NCIB 9529 / HD100)
29% identity, 92% coverage of query (110 bits)
sugA / P9WG03 ABC-type trehalose transporter integral membrane protein from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see 2 papers)
SUGA_MYCTU / P9WG03 Trehalose transport system permease protein SugA from Mycobacterium tuberculosis (strain ATCC 25618 / H37Rv) (see paper)
TC 3.A.1.1.31 / O50452 PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGA, component of The trehalose-recycling ABC transporter, LpqY-SugA-SugB-SugC (essential for virulence) from Mycobacterium tuberculosis (see 2 papers)
32% identity, 92% coverage of query (109 bits)
Dshi_0548 ABC transporter for Xylitol, permease component 1 from Dinoroseobacter shibae DFL-12
33% identity, 78% coverage of query (107 bits)
7cagA / A0R2C2 Mycobacterium smegmatis lpqy-sugabc complex in the catalytic intermediate state (see paper)
31% identity, 87% coverage of query (106 bits)
TC 3.A.1.1.16 / Q8TZP9 MalF, component of Maltooligosaccharide porter (Maltose is not a substrate, but maltotriose is.) from Pyrococcus furiosus
31% identity, 70% coverage of query (100 bits)
TC 3.A.1.1.7 / O51924 MalF, component of Maltose/trehalose porter from Thermococcus litoralis (see paper)
37% identity, 70% coverage of query (99.8 bits)
MELD_BACSU / O34706 Melibiose/raffinose/stachyose import permease protein MelD from Bacillus subtilis (strain 168) (see paper)
30% identity, 70% coverage of query (97.8 bits)
PS417_22140 glucose/xylose ABC transporter, permease component 2 from Pseudomonas simiae WCS417
30% identity, 73% coverage of query (97.1 bits)
TC 3.A.1.1.30 / Q88P37 GtsB (GLcF), component of Glucose porter, GtsABCD from Pseudomonas putida (strain KT2440) (see paper)
31% identity, 73% coverage of query (96.3 bits)
TC 3.A.1.1.11 / Q93KC0 TogM, component of Saturated and unsaturated oligogalacturonide transporter, TogMNAB (transports di- to tetrasaccharide pectin degradation products which consist of D-galacuronate, sometimes with 4-deoxy-L-threo-5-hexosulose uronate at the reducing end of the oligosaccharide) (Hugouvieux-Cotte-Pattat et al. 2001). Regulated by pectin utilization regulator KdgR from Erwinia chrysanthemi (see paper)
28% identity, 85% coverage of query (95.5 bits)
TC 3.A.1.1.42 / TC 3.A.1.1.43 / Q9FBS6 Putative sugar-transporter integral membrane protein, component of α-glucoside uptake permease, Agl3E/Agl3F/Agl3G. Plays a role in normal morphogenesis and antibiotic production. Strongly induced by trehalose and melibiose, and weakly induced by lactose and glycerol but not glucose (Hillerich and Westpheling 2006).The operon is controlled by a GntR homologue, Agl3R, and downstream of the gntR from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
29% identity, 70% coverage of query (93.6 bits)
Ac3H11_2943 ABC transporter for D-Sorbitol, permease component 2 from Acidovorax sp. GW101-3H11
31% identity, 73% coverage of query (92.4 bits)
TC 3.A.1.1.28 / Q00750 MsmF aka SMU.879, component of The raffinose/stachyose transporter, MsmEFGK (MalK (3.A.1.1.27) can probably substitute for MsmK; Webb et al., 2008). This system may also transport melibiose, isomaltotriose and sucrose as well as isomaltosaccharides from Streptococcus mutans (see 2 papers)
32% identity, 71% coverage of query (91.7 bits)
TC 3.A.1.1.50 / Q5SLB6 Sugar ABC transporter, permease protein, component of Probable glycerophosphocholine (GPC) uptake porter (Chandravanshi et al. 2016). The system may include a receptor and three membrane proteins (of 378 aas and 6 TMSs, 299 aas and 7 TMSs, and 113 aas and 3 TMSs (?). The ATPase has not been identified from Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579)
28% identity, 77% coverage of query (87.8 bits)
SMc02872 ABC transporter for N-Acetyl-D-glucosamine, permease protein 1 from Sinorhizobium meliloti 1021
29% identity, 79% coverage of query (87.8 bits)
TC 3.A.1.1.48 / D6ZW63 MalF-type ABC sugar transport systems permease component, component of The lacto-N-biose I (LNB; Gal β-1,3-GlcNAc)/galacto-N-biose (GNB; Gal β-1,3-GalNAc) transporter from Bifidobacterium longum subsp. longum (strain JDM301)
26% identity, 97% coverage of query (87.0 bits)
GGTC_SYNY3 / Q55472 Osmoprotective compounds uptake permease protein GgtC from Synechocystis sp. (strain PCC 6803 / Kazusa) (see paper)
TC 3.A.1.1.32 / Q55472 Membrane bound sugar transport protein, component of The glucosylglycerol uptake transporter (functions in osmoprotection and also transports sucrose and trehalose (Mikkat and Hagemann, 2000) (most similar to 3.A.1.1.8) from Synechocystis sp. (strain PCC 6803) (see paper)
29% identity, 83% coverage of query (86.7 bits)
YcjO / b1311 putative ABC transporter membrane subunit YcjO from Escherichia coli K-12 substr. MG1655 (see 2 papers)
TC 3.A.1.1.46 / P0AFR7 Inner membrane ABC transporter permease protein YcjO, component of Probable glucoside uptake porter, YcjNOPV from Escherichia coli (strain K12)
30% identity, 73% coverage of query (85.1 bits)
TC 3.A.1.1.44 / Q9KZ07 Putative maltose permease, component of MalEFG (K unknown), involved in maltose and maltodextrin uptake from Streptomyces coelicolor (strain ATCC BAA-471 / A3(2) / M145)
28% identity, 84% coverage of query (82.8 bits)
mtlF / Q4KC56 polyol ABC-type transporter permease component MtlF from Pseudomonas fluorescens (strain ATCC BAA-477 / NRRL B-23932 / Pf-5) (see paper)
32% identity, 73% coverage of query (82.0 bits)
PS417_12710 ABC transporter for D-Mannitol and D-Sorbitol, permease component 2 from Pseudomonas simiae WCS417
30% identity, 94% coverage of query (81.6 bits)
AO356_00020 ABC transporter for D-Sorbitol, permease component 2 from Pseudomonas fluorescens FW300-N2C3
32% identity, 79% coverage of query (80.5 bits)
TC 3.A.1.1.18 / Q8RJU9 NgcF, component of N-Acetylglucosamine/N,N'-diacetyl chitobiose porter (NgcK (C) not identified) from Streptomyces olivaceoviridis (Streptomyces corchorusii) (see paper)
30% identity, 75% coverage of query (80.5 bits)
Pf6N2E2_1962 ABC transporter for D-sorbitol, permease component 1 from Pseudomonas fluorescens FW300-N2E2
32% identity, 79% coverage of query (80.5 bits)
TC 3.A.1.1.49 / O30492 MtlF, component of The polyol (mannitol, glucitol (sorbitol), arabitol (arabinitol; lyxitol)) uptake porter, MtlEFGK from Pseudomonas fluorescens
32% identity, 73% coverage of query (80.1 bits)
PGA1_c13200 ABC transporter for D-Sorbitol, permease component 2 from Phaeobacter inhibens BS107
32% identity, 89% coverage of query (79.7 bits)
TC 3.A.1.1.33 / Q8KN18 Putative sugar transporter integral membrane protein, component of The N,N'-diacetylchitobiose uptake transporter, DasABC/MsiK (MsiK energizes several ABC transporters (see 3.A.1.1.23)) from Streptomyces sp. 139 (see 2 papers)
27% identity, 83% coverage of query (75.1 bits)
PGA1_c27940 N-Acetyl-D-glucosamine ABC transport system, permease component 1 from Phaeobacter inhibens BS107
27% identity, 83% coverage of query (74.7 bits)
TC 3.A.1.1.22 / Q9X0T0 MalF1; aka Maltose ABC transporter, permease protein, component of The maltose, maltotriose, mannotetraose (MalE1)/maltose, maltotriose, trehalose (MalE2) porter (Nanavati et al., 2005). For MalG1 (823aas) and MalG2 (833aas), the C-terminal transmembrane domain with 6 putative TMSs is preceded by a single N-terminal TMS and a large (600 residue) hydrophilic region showing sequence similarity to MLP1 and 2 (9.A.14; e-12 & e-7) as well as other proteins from Thermotoga maritima (see paper)
30% identity, 76% coverage of query (74.7 bits)
SMc04258 ABC transporter for D-Cellobiose and D-Salicin, permease component 2 from Sinorhizobium meliloti 1021
27% identity, 70% coverage of query (73.6 bits)
BPHYT_RS16110 ABC transporter for D-Sorbitol, permease component 2 from Burkholderia phytofirmans PsJN
29% identity, 79% coverage of query (72.4 bits)
Dshi_1651 glucose/maltose/trehalose/sucrose ABC transporter, permease component 1 from Dinoroseobacter shibae DFL-12
29% identity, 92% coverage of query (72.0 bits)
TC 3.A.1.1.23 / Q9X9R6 CBP protein aka CebF, component of The cellobiose/cellotriose (and possibly higher cellooligosaccharides), CebEFGMsiK [MsiK functions to energize several ABC transporters including those for maltose/maltotriose and trehalose] from Streptomyces reticuli (see paper)
30% identity, 71% coverage of query (72.0 bits)
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Lawrence Berkeley National Laboratory