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Searching for up to 100 curated homologs for AZOBR_RS29690 FitnessBrowser__azobra:AZOBR_RS29690 (789 a.a.)

Found high-coverage hits (≥70%) to 100 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

picA1 / A0A1X9WE62 picolinate 6-hydroxylase α subunit from Alcaligenes faecalis (see paper)
    53% identity, 97% coverage of query (850 bits)

spmA / F8G0N9 3-succinoylpyridine monooxygenase oxygenase subunit from Pseudomonas putida (strain DSM 28022 / S16) (see paper)
    51% identity, 98% coverage of query (747 bits)

1t3qB / P72224 Crystal structure of quinoline 2-oxidoreductase from pseudomonas putida 86 (see paper)
    37% identity, 97% coverage of query (457 bits)

P72224 quinoline 2-oxidoreductase (subunit 1/3) (EC 1.3.99.17) from Pseudomonas putida (see paper)
    37% identity, 97% coverage of query (456 bits)

AAK64263.1 ndhL from Paenarthrobacter nicotinovorans (see paper)
    35% identity, 98% coverage of query (430 bits)

CDHA_PSEU3 / D7REY3 Caffeine dehydrogenase subunit alpha; Caffeine dehydrogenase large subunit; EC 1.17.5.2 from Pseudomonas sp. (strain CBB1) (see paper)
    36% identity, 98% coverage of query (422 bits)

ndhC / Q59129 NdhC (EC 1.5.99.4) from Paenarthrobacter nicotinovorans (see 2 papers)
Q59129 nicotine dehydrogenase (EC 1.5.99.4) from Paenarthrobacter nicotinovorans (see 2 papers)
    35% identity, 98% coverage of query (421 bits)

D5G1Y2 anaerobic carbon-monoxide dehydrogenase (subunit 3/3) (EC 1.2.7.4) from Mycobacterium sp. (see paper)
    36% identity, 97% coverage of query (406 bits)

Q96XN5 glyceraldehyde dehydrogenase (FAD-containing) (subunit 3/3) (EC 1.2.99.8) from Sulfurisphaera tokodaii (see paper)
    33% identity, 95% coverage of query (367 bits)

1ffuB / P19913 Carbon monoxide dehydrogenase from hydrogenophaga pseudoflava which lacks the mo-pyranopterin moiety of the molybdenum cofactor (see paper)
    32% identity, 97% coverage of query (367 bits)

DCML_HYDPS / P19913 Carbon monoxide dehydrogenase large chain; CO dehydrogenase subunit L; CO-DH L; EC 1.2.5.3 from Hydrogenophaga pseudoflava (Pseudomonas carboxydoflava) (see paper)
P19913 aerobic carbon monoxide dehydrogenase (subunit 3/3) (EC 1.2.5.3) from Hydrogenophaga pseudoflava (see 2 papers)
    32% identity, 97% coverage of query (367 bits)

1ffvB Carbon monoxide dehydrogenase from hydrogenophaga pseudoflava
    32% identity, 97% coverage of query (367 bits)

F9VNL4 glyceraldehyde dehydrogenase (FAD-containing) (subunit 3/3) (EC 1.2.99.8) from Sulfurisphaera tokodaii (see paper)
    33% identity, 97% coverage of query (347 bits)

Q96Y29 glyceraldehyde dehydrogenase (FAD-containing) (subunit 3/3) (EC 1.2.99.8) from Sulfurisphaera tokodaii (see paper)
    32% identity, 97% coverage of query (336 bits)

7dqxD / Q933N0 Crystal structure of xanthine dehydrogenase family protein
    32% identity, 98% coverage of query (332 bits)

kdhC / Q933N0 ketone dehydrogenase large subunit (EC 1.5.99.14) from Paenarthrobacter nicotinovorans (see paper)
KDHC_PAENI / Q933N0 6-hydroxypseudooxynicotine dehydrogenase complex subunit gamma; Ketone dehydrogenase large molybdopterin subunit; EC 1.5.99.14 from Paenarthrobacter nicotinovorans (Arthrobacter nicotinovorans) (see 2 papers)
AAK64253.1 kdhL from Paenarthrobacter nicotinovorans (see paper)
kdhL / CAC37487.1 ketone dehydrogenase large subunit from Paenarthrobacter nicotinovorans (see paper)
    32% identity, 98% coverage of query (331 bits)

atcA / A0A127F6U7 1-testosterone hydratase/dehydrogenase α subunit (EC 1.17.99.11) from Steroidobacter denitrificans (see 2 papers)
A0A127F6U7 3-oxo-DELTA1-steroid hydratase/dehydrogenase (subunit 3/3) (EC 1.17.99.11) from Steroidobacter denitrificans (see paper)
    32% identity, 98% coverage of query (330 bits)

4zohA / Q96Y29 Crystal structure of glyceraldehyde oxidoreductase (see paper)
    33% identity, 95% coverage of query (330 bits)

SSO2639 / Q97VI4 glycolaldehyde oxidoreductase large subunit from Saccharolobus solfataricus (strain ATCC 35092 / DSM 1617 / JCM 11322 / P2) (see paper)
    31% identity, 98% coverage of query (327 bits)

DCML_AFIC5 / P19919 Carbon monoxide dehydrogenase large chain; CO dehydrogenase subunit L; CO-DH L; EC 1.2.5.3 from Afipia carboxidovorans (strain ATCC 49405 / DSM 1227 / KCTC 32145 / OM5) (Oligotropha carboxidovorans) (see 4 papers)
P19919 aerobic carbon monoxide dehydrogenase (subunit 3/3) (EC 1.2.5.3); anaerobic carbon-monoxide dehydrogenase (subunit 3/3) (EC 1.2.7.4) from Afipia carboxidovorans (see 3 papers)
    31% identity, 95% coverage of query (313 bits)

1n63B / P19919 Crystal structure of the cu,mo-co dehydrogenase (codh); carbon monoxide reduced state (see paper)
    31% identity, 95% coverage of query (313 bits)

1zxiB Reconstituted co dehydrogenase from oligotropha carboxidovorans
    31% identity, 95% coverage of query (313 bits)

1n62B Crystal structure of the mo,cu-co dehydrogenase (codh), n- butylisocyanide-bound state
    31% identity, 95% coverage of query (313 bits)

1n5wB Crystal structure of the cu,mo-co dehydrogenase (codh); oxidized form
    31% identity, 95% coverage of query (313 bits)

1n60B Crystal structure of the cu,mo-co dehydrogenase (codh); cyanide- inactivated form
    31% identity, 95% coverage of query (313 bits)

cutA / Q4J6M3 aldehyde dehydrogenase α subunit (EC 1.2.99.8) from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
CUTA_SULAC / Q4J6M3 Glyceraldehyde dehydrogenase large chain; Glyceraldehyde dehydrogenase subunit A; Glyceraldehyde dehydrogenase subunit alpha; EC 1.2.99.8 from Sulfolobus acidocaldarius (strain ATCC 33909 / DSM 639 / JCM 8929 / NBRC 15157 / NCIMB 11770) (see paper)
Q4J6M3 glyceraldehyde dehydrogenase (FAD-containing) (subunit 3/3) (EC 1.2.99.8) from Sulfolobus acidocaldarius (see paper)
    30% identity, 98% coverage of query (306 bits)

Build an alignment

Build an alignment for AZOBR_RS29690 and 26 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

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Change minimum %identity:

Additional hits (identity < 30%)

1rm6A / O33819 Structure of 4-hydroxybenzoyl-coa reductase from thauera aromatica (see paper)
    29% identity, 98% coverage of query (242 bits)

hcrA / O33819 4-hydroxybenzoyl-CoA reductase α subunit (EC 1.1.7.1) from Thauera aromatica (see paper)
HCRA_THAAR / O33819 4-hydroxybenzoyl-CoA reductase subunit alpha; 4-HBCR subunit alpha; EC 1.1.7.1 from Thauera aromatica (see 3 papers)
hcrA / CAA05038.1 4-Hydroxybenzoyl-CoA reductase alpha-subunit from Thauera aromatica (see paper)
    29% identity, 98% coverage of query (241 bits)

hcrA / Q5P3F3 4-hydroxybenzoyl-CoA reductase, α subunit (EC 1.1.7.1) from Aromatoleum aromaticum (strain EbN1) (see 3 papers)
    30% identity, 98% coverage of query (239 bits)

YgeS / b2866 putative xanthine dehydrogenase molybdenum-binding subunit XdhA (EC 1.17.1.4) from Escherichia coli K-12 substr. MG1655 (see 2 papers)
xdhA / Q46799 putative xanthine dehydrogenase molybdenum-binding subunit XdhA (EC 1.17.1.4) from Escherichia coli (strain K12) (see 2 papers)
XDHA_ECOLI / Q46799 Putative xanthine dehydrogenase molybdenum-binding subunit XdhA; EC 1.17.1.4 from Escherichia coli (strain K12) (see paper)
Q46799 xanthine dehydrogenase (subunit 2/2) (EC 1.17.1.4) from Escherichia coli (see paper)
xdhA xanthine dehydrogenase; EC 1.17.1.4 from Escherichia coli K12 (see paper)
    27% identity, 95% coverage of query (223 bits)

hbaC / Q6NC04 4-hydroxybenzoyl-CoA reductase HbaC subunit (EC 1.1.7.1) from Rhodopseudomonas palustris (strain ATCC BAA-98 / CGA009) (see 7 papers)
    27% identity, 95% coverage of query (221 bits)

1dgjA / Q9REC4 Crystal structure of the aldehyde oxidoreductase from desulfovibrio desulfuricans atcc 27774 (see paper)
    28% identity, 93% coverage of query (185 bits)

Q46509 aldehyde dehydrogenase (FAD-independent) (EC 1.2.99.7) from Megalodesulfovibrio gigas (see 4 papers)
4c7yA / Q46509 Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with sodium dithionite and sodium sulfide (see paper)
    27% identity, 94% coverage of query (183 bits)

4usaA Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with trans-cinnamaldehyde
    27% identity, 94% coverage of query (183 bits)

4us9A Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with 3- phenylpropionaldehyde
    27% identity, 94% coverage of query (183 bits)

4us8A Aldehyde oxidoreductase from desulfovibrio gigas (mop), soaked with benzaldehyde
    27% identity, 94% coverage of query (183 bits)

3fc4A Ethylene glycol inhibited form of aldehyde oxidoreductase from desulfovibrio gigas
    27% identity, 94% coverage of query (183 bits)

3fahA Glycerol inhibited form of aldehyde oxidoreductase from desulfovibrio gigas
    27% identity, 94% coverage of query (183 bits)

1sijA Crystal structure of the aldehyde dehydrogenase (a.K.A. Aor or mop) of desulfovibrio gigas covalently bound to [aso3]-
    27% identity, 94% coverage of query (183 bits)

Q46509 Aldehyde oxidoreductase; Molybdenum iron sulfur protein; EC 1.2.99.7 from Megalodesulfovibrio gigas (Desulfovibrio gigas)
    27% identity, 94% coverage of query (183 bits)

XDHD_BACSU / O32144 Probable xanthine dehydrogenase subunit D; XDHase subunit D; EC 1.17.1.4 from Bacillus subtilis (strain 168) (see paper)
pucD / GB|CAB15238.1 xanthine dehydrogenase subunit D; EC 1.17.1.4 from Bacillus subtilis (see paper)
    26% identity, 95% coverage of query (171 bits)

Dshi_2959 Xanthine dehydrogenase (EC 1.17.1.4) from Dinoroseobacter shibae DFL-12
    26% identity, 95% coverage of query (161 bits)

YgfN / b2881 fused putative xanthine/hypoxanthine oxidase: molybdopterin-binding subunit and Fe-S binding subunit from Escherichia coli K-12 substr. MG1655 (see 5 papers)
xdhD / Q46814 fused putative xanthine/hypoxanthine oxidase: molybdopterin-binding subunit and Fe-S binding subunit from Escherichia coli (strain K12) (see 5 papers)
XDHD_ECOLI / Q46814 Probable hypoxanthine oxidase XdhD; EC 1.-.-.- from Escherichia coli (strain K12) (see paper)
    24% identity, 97% coverage of query (159 bits)

Q5QE79 aldehyde oxidase (EC 1.2.3.1) from Rattus norvegicus (see paper)
    25% identity, 96% coverage of query (142 bits)

4uhxA Human aldehyde oxidase in complex with phthalazine and thioridazine
    24% identity, 95% coverage of query (140 bits)

8emtA / Q06278 Cryo-em analysis of the human aldehyde oxidase from liver (see paper)
    24% identity, 95% coverage of query (139 bits)

AOXA_MACFA / Q5FB27 Aldehyde oxidase 1; Azaheterocycle hydroxylase 1; EC 1.2.3.1; EC 1.17.3.- from Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey) (see paper)
Q5FB27 aldehyde oxidase (EC 1.2.3.1) from Macaca fascicularis (see 2 papers)
    24% identity, 95% coverage of query (139 bits)

AOX1 / Q06278 aldehyde oxidase monomer (EC 1.2.3.1) from Homo sapiens (see 5 papers)
AOXA_HUMAN / Q06278 Aldehyde oxidase; Aldehyde oxidase 1; Azaheterocycle hydroxylase; EC 1.2.3.1; EC 1.17.3.- from Homo sapiens (Human) (see 14 papers)
Q06278 aldehyde oxidase (EC 1.2.3.1) from Homo sapiens (see 5 papers)
    24% identity, 95% coverage of query (136 bits)

AOXD_CAVPO / H9TB18 Aldehyde oxidase 4; Aldehyde oxidase homolog 2; Azaheterocycle hydroxylase 4; Retinal oxidase; EC 1.2.3.1; EC 1.17.3.- from Cavia porcellus (Guinea pig) (see paper)
    25% identity, 93% coverage of query (136 bits)

7orcB / Q06278 Human aldehyde oxidase in complex with raloxifene (see paper)
    24% identity, 95% coverage of query (136 bits)

AOXD_MOUSE / Q3TYQ9 Aldehyde oxidase 4; Aldehyde oxidase homolog 2; Azaheterocycle hydroxylase 4; Retinal oxidase; EC 1.2.3.1; EC 1.17.3.- from Mus musculus (Mouse) (see 2 papers)
Q3TYQ9 aldehyde oxidase (EC 1.2.3.1) from Mus musculus (see 2 papers)
    25% identity, 96% coverage of query (136 bits)

AOXA_BOVIN / P48034 Aldehyde oxidase 1; Azaheterocycle hydroxylase 1; EC 1.2.3.1; EC 1.17.3.- from Bos taurus (Bovine) (see paper)
P48034 aldehyde oxidase (EC 1.2.3.1) from Bos taurus (see 3 papers)
    24% identity, 93% coverage of query (135 bits)

Q148T8 aldehyde oxidase (EC 1.2.3.1) from Mus musculus (see paper)
    25% identity, 96% coverage of query (135 bits)

Q8R387 aldehyde oxidase (EC 1.2.3.1) from Mus musculus (see paper)
    25% identity, 93% coverage of query (132 bits)

8emtB / Q06278 Cryo-em analysis of the human aldehyde oxidase from liver (see paper)
    24% identity, 95% coverage of query (132 bits)

AOXA_RAT / Q9Z0U5 Aldehyde oxidase 1; Azaheterocycle hydroxylase 1; EC 1.2.3.1; EC 1.17.3.- from Rattus norvegicus (Rat) (see 5 papers)
Q9Z0U5 aldehyde oxidase (EC 1.2.3.1) from Rattus norvegicus (see 4 papers)
    25% identity, 93% coverage of query (132 bits)

F6Y8K6 aldehyde oxidase (EC 1.2.3.1) from Callithrix jacchus (see paper)
    24% identity, 93% coverage of query (132 bits)

AOXA_MOUSE / O54754 Aldehyde oxidase 1; Azaheterocycle hydroxylase 1; Retinal oxidase; EC 1.2.3.1; EC 1.17.3.- from Mus musculus (Mouse) (see 8 papers)
O54754 aldehyde oxidase (EC 1.2.3.1) from Oryctolagus cuniculus (see paper)
    24% identity, 93% coverage of query (131 bits)

Q9VF53 aldehyde oxidase (EC 1.2.3.1); pyridoxal oxidase (EC 1.2.3.8) from Drosophila melanogaster (see 2 papers)
    24% identity, 87% coverage of query (130 bits)

Q2QB48 aldehyde oxidase (EC 1.2.3.1) from Canis lupus familiaris (see 2 papers)
    25% identity, 93% coverage of query (130 bits)

XDH_BLAAD / R4ZGN4 Xanthine dehydrogenase; XD; Xanthine oxidoreductase; Axorp; XOR; EC 1.17.1.4 from Blastobotrys adeninivorans (Yeast) (Arxula adeninivorans) (see 2 papers)
R4ZGN4 xanthine oxidase (EC 1.17.3.2) from Blastobotrys adeninivorans (see paper)
    26% identity, 87% coverage of query (129 bits)

7px0B / Q9VF53 Drosophila melanogaster aldehyde oxidase 1
    24% identity, 87% coverage of query (128 bits)

AOXA_CAVPO / H9TB17 Aldehyde oxidase 1; Azaheterocycle hydroxylase 1; EC 1.2.3.1; EC 1.17.3.- from Cavia porcellus (Guinea pig) (see 2 papers)
    24% identity, 95% coverage of query (127 bits)

A0A1S4F2J6 xanthine dehydrogenase (EC 1.17.1.4) from Aedes aegypti (see paper)
    25% identity, 88% coverage of query (126 bits)

XDH_DROME / P10351 Xanthine dehydrogenase; XD; Protein rosy locus; EC 1.17.1.4 from Drosophila melanogaster (Fruit fly) (see paper)
    26% identity, 91% coverage of query (126 bits)

1jroB / O54051 Crystal structure of xanthine dehydrogenase from rhodobacter capsulatus (see paper)
    27% identity, 96% coverage of query (126 bits)

2w54B Crystal structure of xanthine dehydrogenase from rhodobacter capsulatus in complex with bound inhibitor pterin-6-aldehyde
    27% identity, 96% coverage of query (126 bits)

2w3sB Crystal structure of xanthine dehydrogenase (desulfo form) from rhodobacter capsulatus in complex with xanthine
    27% identity, 96% coverage of query (126 bits)

2w3rB Crystal structure of xanthine dehydrogenase (desulfo form) from rhodobacter capsulatus in complex with hypoxanthine
    27% identity, 96% coverage of query (126 bits)

1jrpB Crystal structure of xanthine dehydrogenase inhibited by alloxanthine from rhodobacter capsulatus
    27% identity, 96% coverage of query (126 bits)

Q2QB50 aldehyde oxidase (EC 1.2.3.1) from Gallus gallus (see 3 papers)
    24% identity, 90% coverage of query (125 bits)

O54051 xanthine dehydrogenase (subunit 1/2) (EC 1.17.1.4) from Rhodobacter capsulatus (see 2 papers)
xdhB / CAA04470.2 xanthine dehydrogenase from Rhodobacter capsulatus (see paper)
    27% identity, 96% coverage of query (125 bits)

GAD3_CAEEL / Q960A1 Probable aldehyde oxidase gad-3; EC 1.2.3.1 from Caenorhabditis elegans (see paper)
Q960A1 aldehyde oxidase (EC 1.2.3.1) from Caenorhabditis elegans (see paper)
    23% identity, 94% coverage of query (123 bits)

3nrzC / P80457 Crystal structure of bovine xanthine oxidase in complex with hypoxanthine (see paper)
    25% identity, 93% coverage of query (120 bits)

3nrzL / P80457 Crystal structure of bovine xanthine oxidase in complex with hypoxanthine (see paper)
    25% identity, 93% coverage of query (120 bits)

3nvyC Crystal structure of bovine xanthine oxidase in complex with quercetin
    25% identity, 93% coverage of query (120 bits)

3nvwC Crystal structure of bovine xanthine oxidase in complex with guanine
    25% identity, 93% coverage of query (120 bits)

3eub4 Crystal structure of desulfo-xanthine oxidase with xanthine
    25% identity, 93% coverage of query (120 bits)

3sr6C Crystal structure of reduced bovine xanthine oxidase in complex with arsenite
    25% identity, 93% coverage of query (120 bits)

3nvzC Crystal structure of bovine xanthine oxidase in complex with indole-3- aldehyde
    25% identity, 93% coverage of query (120 bits)

3nvvC Crystal structure of bovine xanthine oxidase in complex with arsenite
    25% identity, 93% coverage of query (120 bits)

3ns1C Crystal structure of bovine xanthine oxidase in complex with 6- mercaptopurine
    25% identity, 93% coverage of query (120 bits)

3etrC Crystal structure of xanthine oxidase in complex with lumazine
    25% identity, 93% coverage of query (120 bits)

3b9jC Structure of xanthine oxidase with 2-hydroxy-6-methylpurine
    25% identity, 93% coverage of query (120 bits)

O61198 aldehyde oxidase (EC 1.2.3.1) from Caenorhabditis elegans (see paper)
    24% identity, 96% coverage of query (119 bits)

A0A1S4G2F8 xanthine dehydrogenase (EC 1.17.1.4) from Aedes aegypti (see paper)
    25% identity, 88% coverage of query (119 bits)

3ax7A / P80457 Bovine xanthine oxidase, protease cleaved form (see paper)
    25% identity, 93% coverage of query (119 bits)

5y6qC / Q84IX8 Crystal structure of an aldehyde oxidase from methylobacillus sp. Ky4400 (see paper)
    25% identity, 77% coverage of query (118 bits)

XDH_BOVIN / P80457 Xanthine dehydrogenase/oxidase; EC 1.17.1.4; EC 1.17.3.2 from Bos taurus (Bovine) (see 6 papers)
P80457 xanthine dehydrogenase (EC 1.17.1.4); xanthine oxidase (EC 1.17.3.2) from Bos taurus (see 15 papers)
    25% identity, 93% coverage of query (118 bits)

1fo4A / P80457 Crystal structure of xanthine dehydrogenase isolated from bovine milk (see paper)
    25% identity, 93% coverage of query (118 bits)

PS417_20890 Xanthine dehydrogenase (EC 1.17.1.4) from Pseudomonas simiae WCS417
    24% identity, 97% coverage of query (118 bits)

Q6GMC5 aldehyde oxidase (EC 1.2.3.1) from Xenopus laevis (see paper)
    24% identity, 98% coverage of query (118 bits)

3am9A Complex of bovine xanthine dehydrogenase and trihydroxy fyx-051
    25% identity, 93% coverage of query (118 bits)

3amzA Bovine xanthine oxidoreductase urate bound form
    25% identity, 93% coverage of query (118 bits)

1v97A Crystal structure of bovine milk xanthine dehydrogenase fyx-051 bound form
    25% identity, 93% coverage of query (118 bits)

3unaA Crystal structure of bovine milk xanthine dehydrogenase with NAD bound
    25% identity, 93% coverage of query (118 bits)

3bdjA Crystal structure of bovine milk xanthine dehydrogenase with a covalently bound oxipurinol inhibitor
    25% identity, 93% coverage of query (118 bits)

1vdvA Bovine milk xanthine dehydrogenase y-700 bound form
    25% identity, 93% coverage of query (118 bits)

AO1 / B0LAZ9 aldehyde oxidase (EC 1.2.3.1) from Pisum sativum (see paper)
B0LAZ9 aldehyde oxidase (EC 1.2.3.1) from Pisum sativum (see paper)
    23% identity, 86% coverage of query (117 bits)

A0A1L8D6P5 aldehyde oxidase (EC 1.2.3.1) from Plutella xylostella (see paper)
    23% identity, 91% coverage of query (117 bits)

Or start over

by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory