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Searching for up to 100 curated homologs for Ac3H11_1189 FitnessBrowser__acidovorax_3H11:Ac3H11_1189 (317 a.a.)

Found high-coverage hits (≥70%) to 12 curated proteins.

You can add additional sequences or change the %identity threshold for inclusion. Once you have selected sequences, you can build an alignment and a tree.

Hits with ≥ 30% identity

Q93PS4 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase (EC 1.1.1.312) from Comamonas testosteroni (see paper)
    85% identity, 99% coverage of query (571 bits)

proD / Q75T27 α-hydroxy-γ-carboxymuconate ε-semialdehyde dehydrogenase subunit (EC 1.1.1.312) from Pseudomonas straminea (see 2 papers)
proD / BAD04059.1 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase from Pseudomonas straminea (see paper)
    85% identity, 99% coverage of query (568 bits)

ligC / Q9KWL3 LigC (EC 1.1.1.312) from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see paper)
LIGC_SPHSK / Q9KWL3 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase; CHMS dehydrogenase; 2-hydroxy-4-carboxymuconate semialdehyde hemiacetal dehydrogenase; EC 1.1.1.312 from Sphingobium sp. (strain NBRC 103272 / SYK-6) (see paper)
ligC / BAA97119.1 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase from Sphingomonas paucimobilis (see 3 papers)
ligC / BAB88744.1 4-carboxy-2-hydroxymuconate-6-semialdehyde dehydrogenase from Sphingomonas paucimobilis (see 5 papers)
    75% identity, 98% coverage of query (496 bits)

Build an alignment

Build an alignment for Ac3H11_1189 and 3 homologs with ≥ 30% identity

Select sequences

Add sequences from UniProt, PDB, RefSeq, or MicrobesOnline (separate identifiers with commas or spaces):

Or download the sequences

Change minimum %identity:

Additional hits (identity < 30%)

Echvi_3375 predicted 3-ketohexose reductase from Echinicola vietnamensis KMM 6221, DSM 17526
    29% identity, 85% coverage of query (91.3 bits)

Q7NQL0 UDP-N-acetyl-2-amino-2-deoxyglucuronate dehydrogenase (EC 1.1.1.335) from Chromobacterium violaceum (see paper)
    25% identity, 72% coverage of query (68.9 bits)

3q2iA / Q7NQL0 Crystal structure of the wlba dehydrognase from chromobactrium violaceum in complex with nadh and udp-glcnaca at 1.50 a resolution (see paper)
    25% identity, 72% coverage of query (68.9 bits)

3q2kC / Q79H45 Crystal structure of the wlba dehydrogenase from bordetella pertussis in complex with nadh and udp-glcnaca (see paper)
    24% identity, 72% coverage of query (68.2 bits)

3ceaA / F9ULF9 Crystal structure of myo-inositol 2-dehydrogenase (np_786804.1) from lactobacillus plantarum at 2.40 a resolution
    22% identity, 71% coverage of query (61.6 bits)

3m2tA / Q7NY68 The crystal structure of dehydrogenase from chromobacterium violaceum
    23% identity, 97% coverage of query (55.8 bits)

Q8NTY7 inositol 2-dehydrogenase (EC 1.1.1.18) from Corynebacterium glutamicum (see paper)
    25% identity, 73% coverage of query (52.0 bits)

XDH2_HALVD / D4GP30 D-xylose 1-dehydrogenase (NADP(+)) 2; XDH 2; EC 1.1.1.179 from Haloferax volcanii (strain ATCC 29605 / DSM 3757 / JCM 8879 / NBRC 14742 / NCIMB 2012 / VKM B-1768 / DS2) (Halobacterium volcanii) (see paper)
D4GP30 D-xylose 1-dehydrogenase (NADP+, D-xylono-1,5-lactone-forming) (EC 1.1.1.179) from Haloferax volcanii (see paper)
    25% identity, 74% coverage of query (46.6 bits)

6norA / Q70KD1 Crystal structure of gend2 from gentamicin a biosynthesis in complex with NAD (see paper)
    23% identity, 86% coverage of query (45.4 bits)

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by Morgan Price, Arkin group
Lawrence Berkeley National Laboratory